PSMB7 (proteasome 20S subunit beta 7) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: PSMB7 (proteasome 20S subunit beta 7) Canis lupus familiaris
Analyze
Symbol: PSMB7
Name: proteasome 20S subunit beta 7
RGD ID: 12389471
Description: ENCODES a protein that exhibits hydrolase activity (inferred); threonine-type endopeptidase activity (inferred); INVOLVED IN proteolysis involved in protein catabolic process (inferred); ASSOCIATED WITH coat/hair pigmentation trait; atrial fibrillation (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta-type proteasome 7 subunit; proteasome (prosome, macropain) subunit, beta type, 7; proteasome subunit beta 7; proteasome subunit beta type-7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1958,529,646 - 58,593,016 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl958,529,723 - 58,593,016 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha957,726,668 - 57,789,932 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0959,449,060 - 59,512,699 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl959,449,136 - 59,512,699 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1958,207,216 - 58,270,483 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0958,523,766 - 58,587,042 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0958,614,281 - 58,677,679 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Experimental Data Annotations    Click to see Annotation Detail View

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
coat/hair pigmentation trait  IAGP 12801476Coat colour, harlequinOMIAPMID:3998446 more ...

Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Experimental Data Annotations     Click to see Annotation Detail View

Vertebrate Trait

References
Additional References at PubMed
PMID:21256207  


Genomics

Comparative Map Data
PSMB7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1958,529,646 - 58,593,016 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl958,529,723 - 58,593,016 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha957,726,668 - 57,789,932 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0959,449,060 - 59,512,699 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl959,449,136 - 59,512,699 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1958,207,216 - 58,270,483 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0958,523,766 - 58,587,042 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0958,614,281 - 58,677,679 (+)NCBIUU_Cfam_GSD_1.0
PSMB7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389124,353,465 - 124,415,442 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl9124,353,465 - 124,415,444 (-)EnsemblGRCh38hg38GRCh38
GRCh379127,115,744 - 127,177,721 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369126,155,565 - 126,217,542 (-)NCBINCBI36Build 36hg18NCBI36
Build 349124,195,298 - 124,257,275NCBI
Celera997,762,981 - 97,824,932 (-)NCBICelera
Cytogenetic Map9q33.3NCBI
HuRef996,700,699 - 96,790,409 (-)NCBIHuRef
CHM1_19127,264,760 - 127,326,757 (-)NCBICHM1_1
T2T-CHM13v2.09136,551,512 - 136,613,496 (-)NCBIT2T-CHM13v2.0
Psmb7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,478,058 - 38,533,964 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl238,478,048 - 38,534,099 (-)EnsemblGRCm39 Ensembl
GRCm38238,588,046 - 38,643,952 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl238,588,036 - 38,644,087 (-)EnsemblGRCm38mm10GRCm38
MGSCv37238,443,566 - 38,499,426 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36238,410,055 - 38,465,915 (-)NCBIMGSCv36mm8
Celera240,309,890 - 40,367,955 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.42NCBI
Psmb7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2322,357,777 - 22,417,748 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl322,354,698 - 22,417,937 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx325,825,962 - 25,885,969 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0334,410,959 - 34,470,964 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0332,223,450 - 32,283,379 (-)NCBIRnor_WKY
Rnor_6.0322,890,072 - 22,951,718 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl322,871,105 - 22,952,063 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0328,115,649 - 28,176,245 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4318,384,197 - 18,451,208 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1318,280,569 - 18,347,580 (-)NCBI
Celera320,792,720 - 20,851,768 (-)NCBICelera
Cytogenetic Map3q12NCBI
Psmb7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554193,706,226 - 3,761,780 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554193,706,273 - 3,761,603 (+)NCBIChiLan1.0ChiLan1.0
PSMB7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19123,995,678 - 124,057,491 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9123,995,678 - 124,057,483 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0995,475,378 - 95,540,314 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Psmb7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947192,866,027 - 192,921,441 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648712,631,612 - 12,689,936 (-)EnsemblSpeTri2.0
SpeTri2.0NW_00493648712,634,561 - 12,689,914 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSMB7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1265,172,237 - 265,235,387 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11265,172,257 - 265,235,389 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21298,943,412 - 299,006,545 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PSMB7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11213,722,982 - 13,790,427 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1213,728,724 - 13,793,290 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660792,286,572 - 2,349,790 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psmb7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476010,678,673 - 10,738,009 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476010,678,800 - 10,738,008 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PSMB7
582 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000032210   ⟹   ENSCAFP00000029995
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl958,529,723 - 58,593,016 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000080009   ⟹   ENSCAFP00000055819
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl958,529,723 - 58,593,016 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845018883   ⟹   ENSCAFP00845014752
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl959,449,136 - 59,512,699 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845018928   ⟹   ENSCAFP00845014790
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl959,449,136 - 59,512,699 (+)Ensembl
RefSeq Acc Id: NM_001284453   ⟹   NP_001271382
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1958,529,723 - 58,593,016 (+)NCBI
Dog10K_Boxer_Tasha957,726,668 - 57,789,932 (+)NCBI
ROS_Cfam_1.0959,449,136 - 59,512,699 (+)NCBI
UMICH_Zoey_3.1958,207,216 - 58,270,483 (+)NCBI
UNSW_CanFamBas_1.0958,523,766 - 58,587,042 (+)NCBI
UU_Cfam_GSD_1.0958,614,281 - 58,677,679 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038674899   ⟹   XP_038530827
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0959,449,060 - 59,512,698 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001271382 (Get FASTA)   NCBI Sequence Viewer  
  XP_038530827 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ADU04474 (Get FASTA)   NCBI Sequence Viewer  
  ADU04475 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001271382   ⟸   NM_001284453
- UniProtKB: E7BUQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000055819   ⟸   ENSCAFT00000080009
RefSeq Acc Id: ENSCAFP00000029995   ⟸   ENSCAFT00000032210
RefSeq Acc Id: XP_038530827   ⟸   XM_038674899
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MIH2 (UniProtKB/TrEMBL),   A0A8I3N5F1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845014752   ⟸   ENSCAFT00845018883
RefSeq Acc Id: ENSCAFP00845014790   ⟸   ENSCAFT00845018928
Protein Domains
Pr_beta_C

Promoters
RGD ID:13684845
Promoter ID:EPDNEW_C2915
Type:multiple initiation site
Name:PSMB7_1
Description:Canis lupus familiaris proteasome subunit beta 7 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1958,529,726 - 58,529,786EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020224 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030005606 UniProtKB/TrEMBL
  ENSCAFG00040001269 UniProtKB/TrEMBL
  ENSCAFG00845010709 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000029995.5 UniProtKB/TrEMBL
  ENSCAFP00000055819.1 UniProtKB/TrEMBL
  ENSCAFP00030008987.1 UniProtKB/TrEMBL
  ENSCAFP00040002029 UniProtKB/TrEMBL
  ENSCAFP00040002050 UniProtKB/TrEMBL
  ENSCAFP00845014752 ENTREZGENE
  ENSCAFP00845014752.1 UniProtKB/TrEMBL
  ENSCAFP00845014790 ENTREZGENE
  ENSCAFP00845014790.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000032210.5 UniProtKB/TrEMBL
  ENSCAFT00000080009.2 UniProtKB/TrEMBL
  ENSCAFT00030010261.1 UniProtKB/TrEMBL
  ENSCAFT00040002374 UniProtKB/TrEMBL
  ENSCAFT00040002395 UniProtKB/TrEMBL
  ENSCAFT00845018883 ENTREZGENE
  ENSCAFT00845018883.1 UniProtKB/TrEMBL
  ENSCAFT00845018928 ENTREZGENE
  ENSCAFT00845018928.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.20.10 UniProtKB/TrEMBL
InterPro Ntn_hydrolases_N UniProtKB/TrEMBL
  Pept_T1A_subB UniProtKB/TrEMBL
  Proteasome_beta7 UniProtKB/TrEMBL
  Proteasome_bsu_C UniProtKB/TrEMBL
  Proteasome_bsu_CS UniProtKB/TrEMBL
  Proteasome_sua/b UniProtKB/TrEMBL
  Proteasome_suB-type UniProtKB/TrEMBL
KEGG Report cfa:100686423 UniProtKB/TrEMBL
NCBI Gene PSMB7 ENTREZGENE
PANTHER PTHR11599:SF42 UniProtKB/TrEMBL
Pfam Pr_beta_C UniProtKB/TrEMBL
  Proteasome UniProtKB/TrEMBL
PRINTS PROTEASOME UniProtKB/TrEMBL
PROSITE PROTEASOME_BETA_1 UniProtKB/TrEMBL
  PROTEASOME_BETA_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF56235 UniProtKB/TrEMBL
UniProt A0A8C0MIH2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PVP5_CANLF UniProtKB/TrEMBL
  A0A8I3N5F1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SPM9_CANLF UniProtKB/TrEMBL
  E2RPC6_CANLF UniProtKB/TrEMBL
  E7BUQ0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E7BUP9 UniProtKB/TrEMBL
VGNC ID VGNC:55791 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-17 PSMB7  proteasome 20S subunit beta 7  PSMB7  proteasome subunit beta 7  Symbol and/or name change 5135510 APPROVED