HNRNPL (heterogeneous nuclear ribonucleoprotein L)

Gene: HNRNPL (heterogeneous nuclear ribonucleoprotein L) Canis lupus familiaris

Analyze

Symbol:

HNRNPL

Name:

heterogeneous nuclear ribonucleoprotein L

RGD ID:

12385822

Description:

ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); mRNA CDS binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); circadian rhythm (ortholog); negative regulation of mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH brain cancer (ortholog); Breast Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); pronucleus (ortholog); synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

HNRPL

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	114,267,195 - 114,279,107 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	114,267,210 - 114,278,837 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	113,668,694 - 113,682,944 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	114,867,366 - 114,881,619 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	114,869,714 - 114,881,615 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	114,424,849 - 114,439,087 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	114,060,575 - 114,072,464 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	115,054,052 - 115,068,304 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

brain cancer (ISO)

Breast Neoplasms (ISO)

Disease Progression (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

lung cancer (ISO)

maturity-onset diabetes of the young type 1 (ISO)

Sertoli cell-only syndrome (ISO)

Stomach Neoplasms (ISO)

systemic scleroderma (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to amino acid starvation (ISO)

circadian rhythm (ISO)

mRNA processing (IEA)

negative regulation of DNA-templated transcription (IEA)

negative regulation of mRNA splicing, via spliceosome (ISO)

positive regulation of mRNA binding (ISO)

positive regulation of translation (ISO)

regulation of alternative mRNA splicing, via spliceosome (IEA)

regulation of RNA splicing (IEA)

response to peptide (ISO)

Cellular Component

chromatin (IEA)

cytoplasm (IEA)

nucleoplasm (IEA)

nucleus (IEA)

perinuclear region of cytoplasm (ISO)

pronucleus (ISO)

ribonucleoprotein complex (IEA)

ribonucleoprotein granule (IEA)

synapse (ISO)

Molecular Function

mRNA 3'-UTR binding (ISO)

mRNA binding (IEA)

mRNA CDS binding (ISO)

nucleic acid binding (IEA)

pre-mRNA intronic binding (IEA)

protein binding (ISO)

RNA binding (IEA)

transcription cis-regulatory region binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

spliceosome pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

HNRNPL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	114,267,195 - 114,279,107 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	114,267,210 - 114,278,837 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	113,668,694 - 113,682,944 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	114,867,366 - 114,881,619 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	114,869,714 - 114,881,615 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	114,424,849 - 114,439,087 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	114,060,575 - 114,072,464 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	115,054,052 - 115,068,304 (+)	NCBI		UU_Cfam_GSD_1.0

HNRNPL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	38,836,370 - 38,852,347 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	38,836,370 - 38,852,347 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	39,327,010 - 39,342,987 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	44,018,868 - 44,034,819 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	44,018,868 - 44,032,457	NCBI
Celera	19	36,129,470 - 36,145,420 (-)	NCBI		Celera
Cytogenetic Map	19	q13.2	NCBI
HuRef	19	35,773,794 - 35,789,557 (-)	NCBI		HuRef
CHM1_1	19	39,327,480 - 39,343,450 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	41,640,403 - 41,656,404 (-)	NCBI		T2T-CHM13v2.0

Hnrnpl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	28,507,971 - 28,521,693 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	28,507,966 - 28,521,691 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	28,808,546 - 28,822,268 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	28,808,541 - 28,822,266 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	29,595,909 - 29,607,285 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	28,519,673 - 28,531,004 (+)	NCBI		MGSCv36	mm8
Celera	7	23,371,763 - 23,383,139 (+)	NCBI		Celera
Cytogenetic Map	7	B1	NCBI
cM Map	7	16.93	NCBI

Hnrnpl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	93,226,373 - 93,239,084 (+)	NCBI		GRCr8
mRatBN7.2	1	84,098,558 - 84,111,568 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	84,100,879 - 84,111,553 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	89,510,654 - 89,521,604 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	97,969,995 - 97,980,674 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	91,266,512 - 91,277,462 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	86,994,090 - 87,006,776 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	86,996,093 - 87,006,776 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	88,174,400 - 88,187,394 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	83,919,015 - 83,929,698 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	84,005,781 - 84,007,795 (+)	NCBI
Celera	1	78,491,204 - 78,501,887 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

Hnrnpl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	670,559 - 683,540 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	668,177 - 683,540 (+)	NCBI	ChiLan1.0	ChiLan1.0

HNRNPL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	45,140,619 - 45,158,142 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	47,011,145 - 47,027,200 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	35,943,720 - 35,959,795 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	44,493,832 - 44,509,183 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

Hnrnpl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	13,365,722 - 13,378,495 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936661	1,793,801 - 1,806,579 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936661	1,793,791 - 1,806,564 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HNRNPL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	47,643,566 - 47,657,833 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	47,643,561 - 47,655,856 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	43,180,634 - 43,194,945 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HNRNPL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	33,452,705 - 33,469,070 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	33,452,852 - 33,466,284 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	11,466,361 - 11,483,112 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hnrnpl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	12,206,252 - 12,218,173 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	12,206,278 - 12,220,679 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in HNRNPL
105 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	22	6	6	6	6	6	12	8	10	6
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005616609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022425852	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038451841	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038451843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038451854	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038468187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038468188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038468189	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038468190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038468191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038528943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038528944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038528945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038528946	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038528947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038593221	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038657043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038657045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038657046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038657047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038657048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	MH785188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000009103 ⟹ ENSCAFP00000008442

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	1	114,267,210 - 114,278,837 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845008796 ⟹ ENSCAFP00845006933

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	1	114,869,714 - 114,881,615 (+)	Ensembl

RefSeq Acc Id:

XM_005616609 ⟹ XP_005616666

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	114,267,195 - 114,279,107 (+)	NCBI
Dog10K_Boxer_Tasha	1	113,671,048 - 113,682,944 (+)	NCBI

Sequence:

show sequence

GGGTTCTGCGCCGCCATGTCGCGGAGGCTGCTGCCCCGGGCGGAGAAGCGGCGTCGGCGGCTGG
AGCAGAGGCAGCAGCCGGACGAGCAGCGGAGGCGGTCGGGAGCGATGGTGAAGATGGCGGCGGC
GGGCGGCGGAGGCGGCGGTGGCCGCTACTACGGCGGCGGCAGTGAGGGCGGCCGAGCCCCTAAG
CGGCTCAAGACGGACAACGCTGGCGACCAGCACGGAGGCGGTGGCGGCGGCGGTGGAGGAGCCG
GGGCGGCGGGCGGCGGCGGCGGGGAGAACTACGATGACCCACACAAAACCCCTGCCTCCCCGGT
TGTTCACATCAGGGGCTTGATTGACGGCGTGGTGGAAGCTGACCTTGTGGAGGCCTTGCAGGAA
TTTGGACCCATCAGCTATGTGGTAGTAATGCCTAAAAAGAGACAAGCGTTGGTGGAGTTTGAAG
ACGTGCTGGGGGCTTGCAACGCTGTGAACTACGCAGCTGACAACCAAATCTACATTGCTGGCCA
CCCGGCTTTTGTCAATTACTCTACCAGCCAGAAGATCTCCCGGCCCGGGGACTCAGATGACTCC
CGGAGCGTCAACAGCGTGCTTCTCTTTACCATCTTGAACCCGATCTATTCCATTACCACGGATG
TTCTTTACACTATCTGCAACCCTTGTGGTCCTGTCCAGAGAATTGTTATTTTCCGGAAGAATGG
AGTCCAGGCCATGGTGGAATTTGACTCTGTGCAGAGTGCCCAGCGGGCCAAGGCCTCGCTCAAT
GGGGCTGATATTTACTCGGGTTGTTGCACTCTGAAGATTGAATATGCGAAGCCCACACGCTTGA
ATGTGTTCAAGAACGATCAGGATACTTGGGACTACACAAATCCCAATCTCAGTGGACAAGGTGA
CCCTGGCAGCAACCCTAACAAACGCCAGAGACAGCCCCCTCTCCTGGGAGATCACCCCGCAGAA
TATGGAGGGCCCCACGGTGGGTACCACAGCCATTACCATGATGAGGGCTACGGGCCCCCCCCAC
CTCACTACGAAGGGAGAAGGATGGGCCCACCAGTGGGGGGTCACCGTCGGGGCCCAAGTCGCTA
CGGCCCCCAGTATGGGCACCCCCCACCCCCTCCCCCACCACCCGAGTATGGCCCCCACGCCGAC
AGCCCTGTGCTCATGGTCTATGGCTTGGATCAATCTAAGATGAACTGTGATCGGGTCTTCAATG
TCTTCTGCTTGTATGGCAATGTGGAGAAGGTGAAATTCATGAAAAGCAAGCCGGGGGCCGCCAT
GGTGGAGATGGCTGATGGCTATGCTGTGGACCGGGCCATCACTCACCTCAACAACAACTTCATG
TTCGGCCAGAAGCTGAACGTCTGTGTCTCCAAGCAACCGGCCATCATGCCCGGGCAGTCTTACG
GGCTAGAGGACGGGTCCTGCAGTTATAAAGACTTCAGCGAATCCAGGAACAATCGGTTCTCTAC
TCCGGAGCAGGCAGCCAAGAATCGCATCCAGCACCCTAGCAACGTGCTACACTTCTTCAATGCA
CCTCTGGAGGTGACCGAGGAGAACTTCTTCGAGATCTGCGATGAGCTGGGAGTGAAACGGCCAT
CTTCTGTGAAAGTATTCTCAGGCAAAAGTGAACGCAGCTCCTCTGGGCTGCTGGAGTGGGAATC
CAAGAGCGATGCCCTGGAGACTTTGGGCTTCCTGAATCATTACCAGATGAAAAACCCAAATGGT
CCATACCCTTACACTCTGAAGTTGTGTTTCTCCACTGCTCAGCACGCCTCCTAATAGGTGCCCA
GGAAGAGTCCCATCTGAGCAGGAAAACATTTTTCCTTTATGCTGTTTGTTTTGTTTTTTTGTTT
TTTGTTTTTTTTCTTTTTTTTTCCTTTGCAAAAGTTCCTGTATTCCTTTTTTTAAATGCTAGGT
TAGTGGGCTTAACCATAACGGAAACGCTGGAAGTCTGGAGGGGGAGGGGAAGGGGACCTGATAT
CTCCCAAGATTAACCTTCACTTTTTAAAGAATTATTGTACATGTGATTTTTTTTTCCTGTTCAT
ACATTTGTGCTGCCCGTGTACTCTTAGCACATTTCAATAAAATTGTTTGGAAAATAAA

hide sequence

RefSeq Acc Id:

XM_022425852 ⟹ XP_022281560

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	114,267,931 - 114,279,107 (+)	NCBI
Dog10K_Boxer_Tasha	1	113,671,774 - 113,682,944 (+)	NCBI

Sequence:

show sequence

CTATTAAATCTTTATCGCGTCATGGTTCGTGTCGACACAGAAGTTGATCTACTTTGAGCATGTT
CCCCGAGAACAGACTGTGTCCCCGTTTTTGTGGGCTGTGAAAACCAGAAGAAAGGCTTGCGAAA
GGTCTTTTGAGCCGTGTGGGAATTGAACTAAGCTTTGGAACCATCACAAGTTTGCTTAAAAGTA
CCGGGGCTTAAGTGGGAGAACTACGATGACCCACACAAAACCCCTGCCTCCCCGGTTGTTCACA
TCAGGGGCTTGATTGACGGCGTGGTGGAAGCTGACCTTGTGGAGGCCTTGCAGGAATTTGGACC
CATCAGCTATGTGGTAGTAATGCCTAAAAAGAGACAAGCGTTGGTGGAGTTTGAAGACGTGCTG
GGGGCTTGCAACGCTGTGAACTACGCAGCTGACAACCAAATCTACATTGCTGGCCACCCGGCTT
TTGTCAATTACTCTACCAGCCAGAAGATCTCCCGGCCCGGGGACTCAGATGACTCCCGGAGCGT
CAACAGCGTGCTTCTCTTTACCATCTTGAACCCGATCTATTCCATTACCACGGATGTTCTTTAC
ACTATCTGCAACCCTTGTGGTCCTGTCCAGAGAATTGTTATTTTCCGGAAGAATGGAGTCCAGG
CCATGGTGGAATTTGACTCTGTGCAGAGTGCCCAGCGGGCCAAGGCCTCGCTCAATGGGGCTGA
TATTTACTCGGGTTGTTGCACTCTGAAGATTGAATATGCGAAGCCCACACGCTTGAATGTGTTC
AAGAACGATCAGGATACTTGGGACTACACAAATCCCAATCTCAGTGGACAAGGTGACCCTGGCA
GCAACCCTAACAAACGCCAGAGACAGCCCCCTCTCCTGGGAGATCACCCCGCAGAATATGGAGG
GCCCCACGGTGGGTACCACAGCCATTACCATGATGAGGGCTACGGGCCCCCCCCACCTCACTAC
GAAGGGAGAAGGATGGGCCCACCAGTGGGGGGTCACCGTCGGGGCCCAAGTCGCTACGGCCCCC
AGTATGGGCACCCCCCACCCCCTCCCCCACCACCCGAGTATGGCCCCCACGCCGACAGCCCTGT
GCTCATGGTCTATGGCTTGGATCAATCTAAGATGAACTGTGATCGGGTCTTCAATGTCTTCTGC
TTGTATGGCAATGTGGAGAAGGTGAAATTCATGAAAAGCAAGCCGGGGGCCGCCATGGTGGAGA
TGGCTGATGGCTATGCTGTGGACCGGGCCATCACTCACCTCAACAACAACTTCATGTTCGGCCA
GAAGCTGAACGTCTGTGTCTCCAAGCAACCGGCCATCATGCCCGGGCAGTCTTACGGGCTAGAG
GACGGGTCCTGCAGTTATAAAGACTTCAGCGAATCCAGGAACAATCGGTTCTCTACTCCGGAGC
AGGCAGCCAAGAATCGCATCCAGCACCCTAGCAACGTGCTACACTTCTTCAATGCACCTCTGGA
GGTGACCGAGGAGAACTTCTTCGAGATCTGCGATGAGCTGGGAGTGAAACGGCCATCTTCTGTG
AAAGTATTCTCAGGCAAAAGTGAACGCAGCTCCTCTGGGCTGCTGGAGTGGGAATCCAAGAGCG
ATGCCCTGGAGACTTTGGGCTTCCTGAATCATTACCAGATGAAAAACCCAAATGGTCCATACCC
TTACACTCTGAAGTTGTGTTTCTCCACTGCTCAGCACGCCTCCTAATAGGTGCCCAGGAAGAGT
CCCATCTGAGCAGGAAAACATTTTTCCTTTATGCTGTTTGTTTTGTTTTTTTGTTTTTTGTTTT
TTTTCTTTTTTTTTCCTTTGCAAAAGTTCCTGTATTCCTTTTTTTAAATGCTAGGTTAGTGGGC
TTAACCATAACGGAAACGCTGGAAGTCTGGAGGGGGAGGGGAAGGGGACCTGATATCTCCCAAG
ATTAACCTTCACTTTTTAAAGAATTATTGTACATGTGATTTTTTTTTCCTGTTCATACATTTGT
GCTGCCCGTGTACTCTTAGCACATTTCAATAAAATTGTTTGGAAAATAAA

hide sequence

RefSeq Acc Id:

XM_038451841 ⟹ XP_038307769

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	1	113,671,033 - 113,682,944 (+)	NCBI

RefSeq Acc Id:

XM_038451843 ⟹ XP_038307771

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	1	113,668,818 - 113,682,944 (+)	NCBI

RefSeq Acc Id:

XM_038451854 ⟹ XP_038307782

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	1	113,668,694 - 113,682,944 (+)	NCBI

RefSeq Acc Id:

XM_038468187 ⟹ XP_038324115

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	1	114,427,182 - 114,439,087 (+)	NCBI

RefSeq Acc Id:

XM_038468188 ⟹ XP_038324116

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	1	114,427,197 - 114,439,087 (+)	NCBI

RefSeq Acc Id:

XM_038468189 ⟹ XP_038324117

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	1	114,424,971 - 114,439,087 (+)	NCBI

RefSeq Acc Id:

XM_038468190 ⟹ XP_038324118

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	1	114,427,923 - 114,439,087 (+)	NCBI

RefSeq Acc Id:

XM_038468191 ⟹ XP_038324119

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	1	114,424,849 - 114,439,087 (+)	NCBI

RefSeq Acc Id:

XM_038528943 ⟹ XP_038384871

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	1	115,056,390 - 115,068,304 (+)	NCBI

RefSeq Acc Id:

XM_038528944 ⟹ XP_038384872

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	1	115,056,405 - 115,068,304 (+)	NCBI

RefSeq Acc Id:

XM_038528945 ⟹ XP_038384873

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	1	115,054,176 - 115,068,304 (+)	NCBI

RefSeq Acc Id:

XM_038528946 ⟹ XP_038384874

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	1	115,057,131 - 115,068,304 (+)	NCBI

RefSeq Acc Id:

XM_038528947 ⟹ XP_038384875

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	1	115,054,052 - 115,068,304 (+)	NCBI

RefSeq Acc Id:

XM_038593221 ⟹ XP_038449149

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	1	114,060,575 - 114,072,464 (+)	NCBI

RefSeq Acc Id:

XM_038657043 ⟹ XP_038512971

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	114,869,705 - 114,881,619 (+)	NCBI

RefSeq Acc Id:

XM_038657045 ⟹ XP_038512973

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	114,869,720 - 114,881,619 (+)	NCBI

RefSeq Acc Id:

XM_038657046 ⟹ XP_038512974

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	114,867,490 - 114,881,619 (+)	NCBI

RefSeq Acc Id:

XM_038657047 ⟹ XP_038512975

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	114,870,445 - 114,881,619 (+)	NCBI

RefSeq Acc Id:

XM_038657048 ⟹ XP_038512976

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	114,867,366 - 114,881,619 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005616666	(Get FASTA)	NCBI Sequence Viewer
	XP_022281560	(Get FASTA)	NCBI Sequence Viewer
	XP_038307769	(Get FASTA)	NCBI Sequence Viewer
	XP_038307771	(Get FASTA)	NCBI Sequence Viewer
	XP_038307782	(Get FASTA)	NCBI Sequence Viewer
	XP_038324115	(Get FASTA)	NCBI Sequence Viewer
	XP_038324116	(Get FASTA)	NCBI Sequence Viewer
	XP_038324117	(Get FASTA)	NCBI Sequence Viewer
	XP_038324118	(Get FASTA)	NCBI Sequence Viewer
	XP_038324119	(Get FASTA)	NCBI Sequence Viewer
	XP_038384871	(Get FASTA)	NCBI Sequence Viewer
	XP_038384872	(Get FASTA)	NCBI Sequence Viewer
	XP_038384873	(Get FASTA)	NCBI Sequence Viewer
	XP_038384874	(Get FASTA)	NCBI Sequence Viewer
	XP_038384875	(Get FASTA)	NCBI Sequence Viewer
	XP_038449149	(Get FASTA)	NCBI Sequence Viewer
	XP_038512971	(Get FASTA)	NCBI Sequence Viewer
	XP_038512973	(Get FASTA)	NCBI Sequence Viewer
	XP_038512974	(Get FASTA)	NCBI Sequence Viewer
	XP_038512975	(Get FASTA)	NCBI Sequence Viewer
	XP_038512976	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000008442.3
	ENSCAFP00030025543.1
	ENSCAFP00040016604.1
	ENSCAFP00845006933
	ENSCAFP00845006933.1
GenBank Protein	QCB64959	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005616666 ⟸ XM_005616609
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0R2Z4 (UniProtKB/TrEMBL), A0A8C0S671 (UniProtKB/TrEMBL), A0A8I3MVT0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTD NAGDQHGGGGGGGGGAGAAGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPIS YVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNS VLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIY SGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPH GGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEYGPHADSPVLM VYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKL NVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVT EENFFEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYT LKLCFSTAQHAS hide sequence

RefSeq Acc Id:

XP_022281560 ⟸ XM_022425852

- Peptide Label:

isoform X3

- Sequence:

show sequence

MPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLF
TILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCC
TLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYH
SHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEYGPHADSPVLMVYGL
DQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCV
SKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENF
FEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLC
FSTAQHAS

hide sequence

RefSeq Acc Id:

ENSCAFP00000008442 ⟸ ENSCAFT00000009103

RefSeq Acc Id:	XP_038324119 ⟸ XM_038468191
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038324117 ⟸ XM_038468189
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038324115 ⟸ XM_038468187
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038324116 ⟸ XM_038468188
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038324118 ⟸ XM_038468190
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038449149 ⟸ XM_038593221
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038512976 ⟸ XM_038657048
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0KTX8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038512974 ⟸ XM_038657046
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038512971 ⟸ XM_038657043
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0KTX8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038512973 ⟸ XM_038657045
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0R2Z4 (UniProtKB/TrEMBL), A0A8C0S671 (UniProtKB/TrEMBL), A0A8I3MVT0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038512975 ⟸ XM_038657047
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038307782 ⟸ XM_038451854
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0KTX8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038307771 ⟸ XM_038451843
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038307769 ⟸ XM_038451841
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0KTX8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038384875 ⟸ XM_038528947
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0KTX8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038384873 ⟸ XM_038528945
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038384871 ⟸ XM_038528943
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0KTX8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038384872 ⟸ XM_038528944
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0R2Z4 (UniProtKB/TrEMBL), A0A8C0S671 (UniProtKB/TrEMBL), A0A8I3MVT0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038384874 ⟸ XM_038528946
- Peptide Label:	isoform X3

RefSeq Acc Id:

ENSCAFP00845006933 ⟸ ENSCAFT00845008796

Protein Domains

RRM

Promoters

RGD ID:

13682321

Promoter ID:

EPDNEW_C388

Type:

initiation region

Name:

HNRNPL_1

Description:

heterogeneous nuclear ribonucleoprotein L

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	114,267,236 - 114,267,296	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000005652	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030015920	UniProtKB/TrEMBL
	ENSCAFG00040010281	UniProtKB/TrEMBL
	ENSCAFG00845004919	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000009103.5	UniProtKB/TrEMBL
	ENSCAFT00030029301.1	UniProtKB/TrEMBL
	ENSCAFT00040019134.1	UniProtKB/TrEMBL
	ENSCAFT00845008796	ENTREZGENE
	ENSCAFT00845008796.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/TrEMBL
InterPro	HnRNP-L/PTB	UniProtKB/TrEMBL
	hnRNP-L_RRM3	UniProtKB/TrEMBL
	hnRNPL_RRM1	UniProtKB/TrEMBL
	hnRNPL_RRM2	UniProtKB/TrEMBL
	hnRNPL_RRM4	UniProtKB/TrEMBL
	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	PTBP1_RRM	UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/TrEMBL
	RRM_dom	UniProtKB/TrEMBL
KEGG Report	cfa:100855936	UniProtKB/TrEMBL
NCBI Gene	HNRNPL	ENTREZGENE
PANTHER	HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L	UniProtKB/TrEMBL
	MATRIN 3/NUCLEAR PROTEIN 220-RELATED	UniProtKB/TrEMBL
Pfam	RRM_1	UniProtKB/TrEMBL
	RRM_5	UniProtKB/TrEMBL
	RRM_8	UniProtKB/TrEMBL
PROSITE	RRM	UniProtKB/TrEMBL
SMART	RRM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/TrEMBL
UniProt	A0A4D6FT72_CANLF	UniProtKB/TrEMBL
	A0A8C0KTX8	ENTREZGENE
	A0A8C0R2Z4	ENTREZGENE
	A0A8C0S671	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MVT0	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:54847	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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