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Gene: ADSL (adenylosuccinate lyase) Canis lupus familiaris
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Symbol: ADSL
Name: adenylosuccinate lyase
Description: ENCODES a protein that exhibits (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity (inferred); N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (inferred); nucleic acid binding (inferred); INVOLVED IN 'de novo' AMP biosynthetic process (inferred); 'de novo' IMP biosynthetic process (inferred); miRNA mediated inhibition of translation (inferred); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); autistic disorder (ortholog); breast cancer (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Orthologs:
Homo sapiens (human) : ADSL (adenylosuccinate lyase)  HGNC  Alliance
Mus musculus (house mouse) : Adsl (adenylosuccinate lyase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adsl (adenylosuccinate lyase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adsl (adenylosuccinate lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : ADSL (adenylosuccinate lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adsl (adenylosuccinate lyase)
Sus scrofa (pig) : ADSL (adenylosuccinate lyase)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11024,813,854 - 24,832,115 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog Cytomap10 NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations

Genomics

Comparative Map Data

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on ADSL
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12385465
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-10-22
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.