OPRK1 (opioid receptor kappa 1) - Rat Genome Database

Name: OPRK1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: OPRK1 (opioid receptor kappa 1) Canis lupus familiaris

Analyze

Symbol:

OPRK1

Name:

opioid receptor kappa 1

RGD ID:

12384361

Description:

ENCODES a protein that exhibits opioid receptor activity (ortholog); receptor serine/threonine kinase binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting opioid receptor signaling pathway (ortholog); behavioral response to cocaine (ortholog); cellular response to glucose stimulus (ortholog); PARTICIPATES IN nalbuphine pharmacodynamics pathway; ASSOCIATED WITH Cardiac Arrhythmias (ortholog); Cocaine-Related Disorders (ortholog); conditioned taste aversion (ortholog); FOUND IN axon terminus (ortholog); cytosol (ortholog); dendrite (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

kappa-type opioid receptor; kappa-type opioid receptor 1

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	OPRK1 (opioid receptor kappa 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Oprk1 (opioid receptor, kappa 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Oprk1 (opioid receptor, kappa 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Oprk1 (opioid receptor kappa 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	OPRK1 (opioid receptor kappa 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Oprk1 (opioid receptor kappa 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	OPRK1 (opioid receptor kappa 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	OPRK1 (opioid receptor kappa 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Oprk1 (opioid receptor kappa 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	29	5,025,786 - 5,051,919 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	29	5,022,270 - 5,054,223 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cardiac Arrhythmias (ISO)

Cocaine-Related Disorders (ISO)

Experimental Diabetes Mellitus (ISO)

heroin dependence (ISO)

Hyperalgesia (ISO)

Hyperphagia (ISO)

myocardial infarction (ISO)

Pain (ISO)

schizophrenia (ISO)

visual epilepsy (ISO)

withdrawal disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-inhibiting opioid receptor signaling pathway (ISO)

behavioral response to cocaine (ISO)

cellular response to glucose stimulus (ISO)

cellular response to lipopolysaccharide (ISO)

conditioned place preference (ISO)

defense response to virus (ISO)

eating behavior (ISO)

estrous cycle (ISO)

immune response (ISO)

locomotory behavior (ISO)

maternal behavior (ISO)

negative regulation of luteinizing hormone secretion (ISO)

neuropeptide signaling pathway (IBA)

opioid receptor signaling pathway (IBA)

phospholipase C-activating G protein-coupled receptor signaling pathway (ISO)

positive regulation of dopamine secretion (ISO)

positive regulation of eating behavior (ISO)

positive regulation of locomotion (ISO)

positive regulation of neuronal action potential (ISO)

positive regulation of p38MAPK cascade (ISO)

positive regulation of potassium ion transmembrane transport (ISO)

regulation of saliva secretion (ISO)

regulation of sensory perception of pain (ISO)

response to acrylamide (ISO)

response to auditory stimulus (ISO)

response to cocaine (ISO)

response to estrogen (ISO)

response to ethanol (ISO)

response to insulin (ISO)

response to morphine (ISO)

response to radiation (ISO)

sensory perception of pain (IBA)

sensory perception of temperature stimulus (ISO)

Cellular Component

axon terminus (ISO)

cytosol (ISO)

dendrite (ISO)

integral component of membrane (ISO)

integral component of plasma membrane (IBA)

integral component of postsynaptic membrane (ISO)

integral component of presynaptic membrane (ISO)

integral component of synaptic vesicle membrane (ISO)

neuron projection (IBA)

neuronal cell body (ISO)

nucleoplasm (ISO)

perikaryon (ISO)

plasma membrane (ISO)

synapse (ISO)

Molecular Function

dynorphin receptor activity (IBA)

G protein-coupled receptor activity (IBA)

neuropeptide binding (IBA)

opioid receptor activity (ISO)

peptide binding (IBA)

protein binding (ISO)

receptor serine/threonine kinase binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

nalbuphine pharmacodynamics pathway (ISO)

References

Genomics

Comparative Map Data

OPRK1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	29	5,025,786 - 5,051,919 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	29	5,022,270 - 5,054,223 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

OPRK1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	8	53,225,716 - 53,251,697 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p13 Ensembl	8	53,225,724 - 53,251,637 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	8	53,225,724 - 53,251,637 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	8	54,138,276 - 54,164,257 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	54,300,829 - 54,326,747 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	8	54,304,325 - 54,326,525	NCBI
Celera	8	50,129,111 - 50,155,030 (-)	NCBI
Cytogenetic Map	8	q11.23	NCBI
HuRef	8	49,605,704 - 49,631,623 (-)	NCBI		HuRef
CHM1_1	8	54,189,898 - 54,215,870 (-)	NCBI		CHM1_1

Oprk1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	5,658,673 - 5,676,357 (+)	NCBI	GRCm39		mm39
GRCm38	1	5,588,450 - 5,606,134 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	5,588,466 - 5,606,131 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	5,578,574 - 5,592,947 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	1	5,578,574 - 5,592,947 (+)	NCBI			mm8
Celera	1	5,572,638 - 5,587,007 (+)	NCBI		Celera
Cytogenetic Map	1	A1	NCBI
cM Map	1	1.89	NCBI

Oprk1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	5	13,742,655 - 13,760,460 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	13,744,658 - 13,760,305 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	18,519,763 - 18,534,188 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	14,040,848 - 14,055,273 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	5	14,037,659 - 14,055,460 (-)	NCBI
Celera	5	13,240,420 - 13,258,214 (-)	NCBI		Celera
Cytogenetic Map	5	q12	NCBI

Oprk1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955454	12,744,765 - 12,752,226 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955454	12,741,577 - 12,751,282 (-)	NCBI	ChiLan1.0	ChiLan1.0

OPRK1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	8	47,030,643 - 47,056,577 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	47,029,313 - 47,056,577 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	8	49,650,844 - 49,677,494 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

Oprk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936496	280,593 - 305,900 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OPRK1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	77,399,198 - 77,426,522 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	77,399,298 - 77,429,025 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	84,469,581 - 84,499,310 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OPRK1
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	49,337,308 - 49,364,724 (-)	NCBI
ChlSab1.1 Ensembl	8	49,341,427 - 49,362,947 (-)	Ensembl

Oprk1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624735	2,301,248 - 2,325,678 (+)	NCBI

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium									5
Low			7						6
Below cutoff	5	3	10	4	6	4	1	1	1	8	2	3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001314092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038441075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000364	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KP676947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCAFT00000047718 ⟹ ENSCAFP00000041119

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	29	5,025,786 - 5,051,919 (-)	Ensembl

RefSeq Acc Id:

NM_001314092 ⟹ NP_001301021

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	29	5,025,786 - 5,051,879 (-)	NCBI

Sequence:

show sequence

ATGGAGTCCCCGGTCCAGATCTTTCGCGGGGAGCCGGGCCCCACCTGCTCCGCGAGCACCTGCC
TGCTCCCCAACGGCAGCGGCTGGCTGCCCGGCTGGGCCGAGACGGAAGGCAACCACAGCGGCGG
CTCCGAGGGCGCGCAGCTCGAGTCCGCGCACATCTCTCCCGCCATCCCCGTCATCATCACGGCT
GTCTACTCCGTGGTGTTCGTCGTGGGCTTGGTGGGCAACTCCCTGGTCATGTTCGTGATCATCC
GATACACAAAGATGAAGACAGCAACCAACATTTATATATTTAACCTGGCGTTGGCGGATGCTTT
AGTTACTACAACCATGCCCTTCCAGAGCACGGTCTATCTGATGAATTCCTGGCCATTTGGGGAT
GTGCTGTGCAAGATAGTTATTTCCATTGATTATTATAACATGTTTACCAGCATATTCACCTTGA
CCATGATGAGTGTGGACCGATACATTGCTGTGTGCCATCCTGTCAAGGCTTTAGACTTTCGCAC
ACCCATGAAGGCAAAGATCATCAACATCTGTATTTGGCTCTTATCGTCATCTGTTGGCATATCT
GCAATAGTTCTTGGAGGGACCAAAGTCAGGGAAGATGTGGATGTCATCGAGTGCTCCTTGCAAT
TCCCAGATGATGATTACTCCTGGTGGGACCTCTTCATGAAGATCTGTGTCTTCATCTTTGCCTT
TGTGATCCCTGTCCTCATCATCATCATCTGTTACACCCTGATGATCCTACGTTTGAAGAGCGTC
CGACTCCTTTCTGGCTCCCGAGAGAAAGATCGCAACCTTCGTCGGATCACCAGGCTGGTCCTTG
TGGTGGTGGCAGTCTTTATCATCTGTTGGACACCCATTCACATTTTCATCCTTGTGGAAGCTCT
GGGGAATGCCTCTCACAGCACAGCTGCCCTCTCCAGCTATTACTTCTGCATTGCCTTGGGTTAC
ACCAACAGCAGTCTGAACCCCATTCTCTATGCCTTTCTTGATGAAAACTTCAAGCGGTGTTTCA
GGGACTTCTGCTTTCCAATTAAGATGAGGATGGAGCGACAGAGCACTAGTAGAGTCAGAAATAC
AGTTCAGGATCCTGCTTACATGAGGGATGTTGATGGGCTAAATAAACCAGTATGA

hide sequence

RefSeq Acc Id:

XM_544080 ⟹ XP_544080

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	29	5,022,270 - 5,054,223 (-)	NCBI

Sequence:

show sequence

CGATCTTAGGGTCCTGGGATCCAGCCCCACGTTGGGATCCAGCAGGGAGTCTGCTTCTCCCTTT
TCTATTCTTTTTTTGTCCTTTCCAAATAACCCCTTCTATATATGTTTTGTCCTTCGGGGAAGAG
TGGCTCTGTAATTGTTCCCTTATATGAAATCACTCTGTGTAATCAGCATATGGTAAGAGACAGA
AACACCTGTGTTTGAGCTCAATTCAGTAATGTTACCAGCTGTATAAGCCACCTGTGTACTAAAT
TTAACAACAAAAACTAACCAATACAGTGAGTGCAAAAGGACAGACATCGTAAATACTCCTTCAA
AAGTGTGTTGAACAGAGACAGTTGTATGTATTTTCAATGCATGAAATCATAAATAGGTAGTAGA
CAGAAAGATAGATGAATAATTCTTTCCTAGCTATTTTCCTTTAACATACTCTTTTTATTTTCTT
TGTTGGATACTGCTTAGTTTTCAAACAAAATGTCTTCCTGGGTTGGTTTGGTGGTAACCTGGGA
TCCCTTTGGCAGGAAATGAGCTCCCAAACAACTGGAGATTTATCTGGAGAAGATTTGTCAGCCA
TCTTCCTAACAGAGAAGGACCCTCAGGCACATGGAGATTCCATCATTCCCATGTTTTGTTATCT
TCTAAAGAAAATCTGCAATCAAAACCTAAAAAAAATGTAAGATCTGATAATACTTTTCAAAACA
CCAATGGCCCCAGGGTTGGAGAGATGTTGTGGGGGCAAAGAAGAGCTTTCCTGTTGTTCTTCGA
ATCACATTGCCAAGAAGAGCTGTGTATTTCGAGGTTGTAGTAAGATTCTGGTGGTCAAATGCCT
TTTTGGGAGTCACAATATCTGAAACAAGGTGGAAGCTCTCTTCTGCGGTCAACTGATGAATGGA
ATGACTGTATAGGCATCCTGATTCCTGTACCCAGTCTGGAAAGGGGAACTTCTCCACTGTCCTT
CAGTGGCTGAGTCCTGGCTCCCCTGTACAGCCAACTTTGGCCTTCCTTCCTTGTCTTCATCATC
CCCTGGGTCTCTTTGCCTGAGGGGACATTTCAGCAGAATCTGACAGATATCCTTGGACTGGTGG
AGTTATGCACAGAAATGATGATGACTGAACTTCTCCATGAGGGTTCAGGTTCTTGGGGGCTCTA
TAAAGAAGGCATCCCAGTGAAGGGAAAGTGGATTTGCAGGGATTAATAAAAGAGAAAGACAATG
TCAACTCCCGGCCCAGCGCCGAGGCCTGAGTAAGGAGAGTGTCTTACTCATTGCAGGTAATAAC
CACGAAATACGGATAATACCTGAGATGCCAGTCTGTGTGTCATCTCAGAGAAGAATGAAAGGAA
CAGAATGAACAGAAATATTCTATTTACGTATATTAAATCGTTAATATCTGATGGCCCGGTCTTA
CTCTAATTGGATTGTTTTGCCACTTTATTTGGATGCGTCATTCAGAATTTCTCCTCTCTTGAAA
GAAGACATGTCTTGAGAACGATGCCCACAGTAGCTCTAGACTTTATTATGAATAATCCAGATGC
ATAATCGCACTGAGGAGGCACACCCTTACTGCTAAAGCTAATCCGCACAGCTGCTAGTCTTAGG
GCCGCCCAGGAGAGGCTGATTGAGGCTCTGGGTAGTTGGTGGTCGGGGAGCCTCGGCTGGGGGC
GCGGCCCGGGCAGGGGCGGGGCGCCGGGGAGCTCCCCGCCCGCCGAGCCCGCGCGCTCCGAGTC
CTTGCAGCGCACGCCTGGCTGAGCCGCCGCGGGCCGTGGGAGCCGCGCTGAGCCGCGCTGAGCC
GCGCTGAGCCGCGGGGACCGGGCTGGGCTGAGAAGGTGCCTCATCCAGGGCGCCGAGCTGCGGG
CGCGCCGCGACTCCAGGGCTGAGACCGCTGCGCGGGTCTCCGGGAGCCGGAGGTTCTGCCTCTG
CTCGCCCTGCACCTGCGGCCGCCGGACCATGGAGTCCCCGGTCCAGATCTTTCGCGGGGAGCCG
GGCCCCACCTGCTCCGCGAGCACCTGCCTGCTCCCCAACGGCAGCGGCTGGCTGCCCGGCTGGG
CCGAGACGGAAGGCAACCACAGCGGCGGCTCCGAGGGCGCGCAGCTCGAGTCCGCGCACATCTC
TCCCGCCATCCCCGTCATCATCACGGCTGTCTACTCCGTGGTGTTCGTCGTGCGCTTGGTGGGC
AACTCCCTGGTCATGTTCGTGATCATCCGATACACAAAGATGAAGACAGCAACCAACATTTATA
TATTTAACCTGGCGTTGGCGGATGCTTTAGTTACTACAACCATGCCCTTCCAGAGCACGGTCTA
TCTGATGAATTCCTGGCCATTTGGGGATGTGCTGTGCAAGATAGTCATTTCCATTGATTATTAT
AACATGTTTACCAGCATATTCACCTTGACCATGATGAGTGTGGACCGATACATTGCTGTGTGCC
ATCCTGTCAAGGCTTTAGACTTTCGCACACCCATGAAGGCAAAGATCATCAACATCTGTATTTG
GCTCTTATCGTCATCTGTTGGCATATCTGCAATAGTTCTTGGAGGGACCAAAGTCAGGGAAGAT
GTGGATGTCATCGAGTGCTCCTTGCAATTCCCAGATGATGATTACTCCTGGTGGGACCTCTTCA
TGAAGATCTGTGTCTTCATCTTTGCCTTTGTGATCCCTGTCCTCATCATCATCATCTGTTACAC
CCTGATGATCCTACGTTTGAAGAGCGTCCGACTCCTTTCTGGCTCCCGAGAGAAAGATCGCAAC
CTTCGTCGGATCACCAGGCTGGTCCTTGTGGTGGTGGCAGTCTTTATCATCTGTTGGACACCCA
TTCACATTTTCATCCTTGTGGAAGCTCTGGGGAATGCCTCTCACAGCACAGCTGCCCTCTCCAG
CTATTACTTCTGCATTGCCTTGGGTTACACCAACAGCAGTCTGAACCCCATTCTCTATGCCTTT
CTTGATGAAAACTTCAAGCGGTGTTTCAGGGACTTCTGCTTTCCAATTAAGATGAGGATGGAGC
GACAGAGCACTAGTAGAGTCAGAAATACAGTTCAGGATCCTGCTTACATGAGGGATGTTGATGG
GCTAAATAAACCAGTATGACTAGTCGTGGAGATGTCTTCTTACAGTTCTTCAGGAAGAGAAGAG
TTTAATGATCTCGGGTTAACTCAGATTAGTACTGAAGTCTAACATGGAAAGATAGAATTTTTAA
CTAACTTTTAGAAATCTCATGGTCTGAAGTCATAAGATGCAGACTGGGTCTGCCACCCAGGTCA
GTGGAAGCATCAAGGTTGTAGGGATGGAGTACAAAAGAATCGAGTAAGCAAATACAGCCCCTTT
CTAAGGCAGGGAAGAAAGGCGGACTCTCAGTTCCTTTGATGAACAAAGAAACAAGCCTTTTTCT
TCTGGTCACCTAGATTTAGTTCAGGACCCATCTGCTGTGGCTTTCCCATGCAATGTGGTTCCAA
AAGCTCTGTTTAGAAAAAAGGACAAGAAAAAAAATATTGGTTTTAGAGCTTAGTGGGCATCTCA
TCCAGATGCTTTACATTGATAACAACACCCTGAATAAAAACAAACACCATTTCCAGGGCACATG
TCCAGCTCACTTTATGCTATACACACACATGTAGTGTGGCTGTGTGGTGACAATTCTGGTTTAG
ATATGGCTTGGACCTACACCTTAGGTGTCTGATGTTCATGTATAATAGGAAATTATCTTGATAT
TTATGAAGTTATTTAAACTGCAAAGGGTGGTTTCCAACATAGCTTAATTTCTTAAAAGGCACAG
TTTGTTTTGCAGCATGCTATTCAGATACATAATTTCATAATAACGCATGTCCTTATGTCAAGAA
ATATAAAGTGATTCAAATATCATTGAAAGTATCTATAGTTTCATCTGTAAATAATAGGATACAT
GCAAATAAAGACTGGGCTTGCCTCTCATATGGGCACTTTCCCGAGGACACACTAACAATATCCC
CTGAGTTACTGACAGTTGATGTGGAAACATTTTGTGGCAACTGAGCTTCTCTCTGGGAATCAGC
CAGGCGTTGTCTCTTTCAGACACTAAGCACCAGTTAGTCCTTCAGTGGTGCTCCTAACTCATGT
GTTAATCAATCATGAAATATTTCACTCATTCCCAGGTTGTTAACTTGGCAGAATCTAATTTATA
TGCAGCATCTCTTCATGAATATATAGCTGTTACCAAATTCTCTCTATCCTTGGATGGAGGGCAT
TTGACTCATGTTGATCTTGGGCTAGGATTTTGTCACTTTTGGCAGAAAGTAGAAATGTTCCTAA
TCGTGGGCTGAACAAGGACATTATGTCACCCGTGGTGCTTGGACATACCTTGCACTGTATTCTG
AAGAGCATTCCAGTTGAGGATAATGCCATGAGCAGCATATTTAGGATAATTTGTCTAAAACTTC
CAGATGATATATTAATTTCCTCATCTTTCTCCTGAAACTTATGATTTCAGAGGTAATGGCTTTT
TTCCTGTAATTTACCTGGGCAGAAAAAAGAGATAATTTAGAAATAACACCAGTCTCTTCTCTTC
TTTAAGCCTATATGTTCTCAGGGCAGCACCCTTTGGAATTTAATGGGAAAATCAAATGTATAGA
CCTACCTACTCATAGACATCATTACACCTATAATTTATGTTCGCTGTGTACTTTCTATCTTGTG
TGTTCTTTCTCTTCTTTTGGAAACAAACCTTGCATTGAAGGCTTCATATGCGGCTTAAGAATTT
TACTATGATGATGTTTGTCTACATTCCAGATTTTCATGGCACCTAACAGATGACTTAAGGCAGA
AAGGCAGGGTTCTTCTGAATGAACCCAAAGTGCTCTTTTGAGCATTTCTTAAATTCCACTGATT
TTCTTTGGTGTTCTTGTATTCTTATAACTAATGTAGATAGGAATGGCTTTAAATATTGGTTGGC
ATTCACCTCATGGTTATAAATCTTGGCTATCACACAGAAGGGATATTTATACAGAGAGTAATTT
CAGTTACAAGCCATACTGATGTGAGAAATATAAAAATCTCTTTATTGAACAGTAAGACCCAAAG
GATTTTTTTGAAGGATTCTTATGCAGTGCAAAAATATACAATTGTGAAATGGAATTATAGTAAT
TATAGTAATGGATTCTCTTTCAGTTAGCACCCCATGTACCCTTATGGCATTTGTTGCCATTATT
GGAGTCTGAACTTTAGCCAGATTATCCTGCATGTCTTTGTATCTAAGTTTGCAGCCCAAGGAGA
GAGAGAAGTAGCTCTGAGTGCCCATGAGAGATGTTCTAAGTTTCTCTATTATTGTGAACACCAA
TTTCTTCAAACTGGAAGGGGAGAGAGGGTGGCTTTGTAATTTCAGGGCACTGCTTTAAGGAATG
AAAAAGTGAATGATATATGTTAGAGAAAATACCACTTACACAAAGTATTCATTTGTCAAAAGTG
TGTATGTTTGCACACATGCACATGCACGTGTAAGTGAGTGTATGTGGCTATGTGTGCATAAAAT
GTATGTGTGCTTGTGTGATCATGTAGGCATTCATATGTGAAATTGTGAGCGAATGTTTTTCTGT
ATATGCATTATGTATGTGCATGCATGTATGTGTGTGAATATATGTGTGAGATTGTGTATGTATA
TGTGAATACACATGTTTGAACATGTGAGTATGCATGAGTATTTGTGTGTGATCATGTATGCATG
TATGCATGAGTATGACTATATGTGTGTGCATGTGTGTGATTATGTGTGCATATGCATGCATGTG
TGTGTGAGATTATGTTTGTCTGTGTCCCATGTCTTGATATTCCTGCTGTCTCATCACAGCAAGG
AGGGCACACTGTTTGCTGTGTCTTTTTGAGACCAGAACTGTGTGTATCTAACCTCAAGATCAAC
TCGACATAAATTCCATATTCCCACCCTGATGACTTCTGGAAGCTAAGATCTAGTGAGGGATAGT
AAAAAGATACAGAGAAAGGTAGCAGCCATACAGGAGGCAGCAATGAGGATGAAAACACATAATT
CTAACTCGGGGGAGACTGGCATTAATGTCTCAGAAATACTGTTAAAAGTCTAAGAGCGTCCCCT
ATGCAAAGAGGTTAAGTCAAAACTCAAAGCATAATGCTAAAAAAGAAACACAGTTTGGGAAGGT
AGTTTTGAAAAAAAAATCAAGGAATATTCATATAAATCTTAAGAAAGTGGTTCTATTCTATGAT
GCAAATACAAGTTACTAAATATATAGAGCCATTATTGGACAATTTATAGATGTTTCATCTAGTA
TAATGAGATGAATAACTGGAATAAAAGGAATACGTTGGCTGGATCTAAATTAGACCTTCTTAAA
AAGAAAACTCTGATAAGGCTGTAAGTCCATCCAATGAGATTTGTTTTCTAAACAAGAGCTGTTT
GGAAGAATCAGTATAAATATGAAAATCCCATTCCCAAAGGGCATAAACCTGTTTGCTCTTAGGC
AGTTTTCTTCTCTGAAACAAAAGTATACTCATATATTCTTTATTGTGTATTATTTTTATTTTGA
ACTTTTGGAAGATGACAACTATGCATTGTATATAAGATTGTGTATCTTGCAGTAAAATAAAAAT
TGCACCTGCTCCAAA

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Protein Sequences


Protein RefSeqs	NP_001301021	(Get FASTA)	NCBI Sequence Viewer
	XP_038297003	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AKE49504	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_544080 ⟸ XM_544080

- Peptide Label:

isoform X1

- Sequence:

show sequence

MESPVQIFRGEPGPTCSASTCLLPNGSGWLPGWAETEGNHSGGSEGAQLESAHISPAIPVIITA
VYSVVFVVRLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGD
VLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPMKAKIINICIWLLSSSVGIS
AIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIICYTLMILRLKSV
RLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGNASHSTAALSSYYFCIALGY
TNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRDVDGLNKPV

hide sequence

RefSeq Acc Id:

NP_001301021 ⟸ NM_001314092

- UniProtKB:

A0A0F6TN93 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MESPVQIFRGEPGPTCSASTCLLPNGSGWLPGWAETEGNHSGGSEGAQLESAHISPAIPVIITA
VYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGD
VLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPMKAKIINICIWLLSSSVGIS
AIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIICYTLMILRLKSV
RLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGNASHSTAALSSYYFCIALGY
TNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRDVDGLNKPV

hide sequence

RefSeq Acc Id:

ENSCAFP00000041119 ⟸ ENSCAFT00000047718

Protein Domains

G_PROTEIN_RECEP_F1_2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000032542	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSCAFP00000041119	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000047718	ENTREZGENE, UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	Kappa_opi_rcpt	UniProtKB/TrEMBL
	Opioid_rcpt	UniProtKB/TrEMBL
KEGG Report	cfa:486951	UniProtKB/TrEMBL
NCBI Gene	OPRK1	ENTREZGENE
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	KAPPAOPIOIDR	UniProtKB/TrEMBL
	OPIOIDR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
UniProt	A0A0F6TN93	ENTREZGENE, UniProtKB/TrEMBL
	J9P639_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:44133	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - SMPDB