OPRK1 (opioid receptor kappa 1) - Rat Genome Database
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Gene: OPRK1 (opioid receptor kappa 1) Canis lupus familiaris
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Symbol: OPRK1
Name: opioid receptor kappa 1
RGD ID: 12384361
Description: ENCODES a protein that exhibits opioid receptor activity (ortholog); receptor serine/threonine kinase binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting opioid receptor signaling pathway (ortholog); behavioral response to cocaine (ortholog); cellular response to glucose stimulus (ortholog); PARTICIPATES IN nalbuphine pharmacodynamics pathway; ASSOCIATED WITH Cardiac Arrhythmias (ortholog); Cocaine-Related Disorders (ortholog); conditioned taste aversion (ortholog); FOUND IN axon terminus (ortholog); cytosol (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: kappa-type opioid receptor; kappa-type opioid receptor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl295,025,786 - 5,051,919 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1295,022,270 - 5,054,223 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
OPRK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl295,025,786 - 5,051,919 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1295,022,270 - 5,054,223 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
OPRK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl853,225,716 - 53,251,697 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl853,225,724 - 53,251,637 (-)EnsemblGRCh38hg38GRCh38
GRCh38853,225,724 - 53,251,637 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37854,138,276 - 54,164,257 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36854,300,829 - 54,326,747 (-)NCBINCBI36hg18NCBI36
Build 34854,304,325 - 54,326,525NCBI
Celera850,129,111 - 50,155,030 (-)NCBI
Cytogenetic Map8q11.23NCBI
HuRef849,605,704 - 49,631,623 (-)NCBIHuRef
CHM1_1854,189,898 - 54,215,870 (-)NCBICHM1_1
Oprk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915,658,673 - 5,676,357 (+)NCBIGRCm39mm39
GRCm3815,588,450 - 5,606,134 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15,588,466 - 5,606,131 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715,578,574 - 5,592,947 (+)NCBIGRCm37mm9NCBIm37
MGSCv3615,578,574 - 5,592,947 (+)NCBImm8
Celera15,572,638 - 5,587,007 (+)NCBICelera
Cytogenetic Map1A1NCBI
cM Map11.89NCBI
Oprk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0513,742,655 - 13,760,460 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl513,744,658 - 13,760,305 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0518,519,763 - 18,534,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4514,040,848 - 14,055,273 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1514,037,659 - 14,055,460 (-)NCBI
Celera513,240,420 - 13,258,214 (-)NCBICelera
Cytogenetic Map5q12NCBI
Oprk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545412,744,765 - 12,752,226 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545412,741,577 - 12,751,282 (-)NCBIChiLan1.0ChiLan1.0
OPRK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1847,030,643 - 47,056,577 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl847,029,313 - 47,056,577 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0849,650,844 - 49,677,494 (-)NCBIMhudiblu_PPA_v0panPan3
Oprk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936496280,593 - 305,900 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OPRK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl477,399,198 - 77,426,522 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1477,399,298 - 77,429,025 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2484,469,581 - 84,499,310 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OPRK1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1849,337,308 - 49,364,724 (-)NCBI
ChlSab1.1 Ensembl849,341,427 - 49,362,947 (-)Ensembl
Oprk1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247352,301,248 - 2,325,678 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5
Low 7 6
Below cutoff 5 3 10 4 6 4 1 1 1 8 2 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000047718   ⟹   ENSCAFP00000041119
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl295,025,786 - 5,051,919 (-)Ensembl
RefSeq Acc Id: NM_001314092   ⟹   NP_001301021
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1295,025,786 - 5,051,879 (-)NCBI
Sequence:
RefSeq Acc Id: XM_544080   ⟹   XP_544080
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1295,022,270 - 5,054,223 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001301021 (Get FASTA)   NCBI Sequence Viewer  
  XP_038297003 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AKE49504 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_544080   ⟸   XM_544080
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001301021   ⟸   NM_001314092
- UniProtKB: A0A0F6TN93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000041119   ⟸   ENSCAFT00000047718
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000032542 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000041119 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000047718 ENTREZGENE, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Kappa_opi_rcpt UniProtKB/TrEMBL
  Opioid_rcpt UniProtKB/TrEMBL
KEGG Report cfa:486951 UniProtKB/TrEMBL
NCBI Gene OPRK1 ENTREZGENE
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  KAPPAOPIOIDR UniProtKB/TrEMBL
  OPIOIDR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
UniProt A0A0F6TN93 ENTREZGENE, UniProtKB/TrEMBL
  J9P639_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:44133 ENTREZGENE