PHETA1 (PH domain containing endocytic trafficking adaptor 1) - Rat Genome Database

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Gene: PHETA1 (PH domain containing endocytic trafficking adaptor 1) Canis lupus familiaris
Analyze
Symbol: PHETA1
Name: PH domain containing endocytic trafficking adaptor 1
RGD ID: 12383763
Description: ENCODES a protein that exhibits protein homodimerization activity (inferred); INVOLVED IN endosome organization (inferred); receptor recycling (inferred); retrograde transport, endosome to Golgi (inferred); ASSOCIATED WITH Colorectal Neoplasms (ortholog); genetic disease (ortholog); FOUND IN clathrin-coated vesicle (inferred); cytoplasmic vesicle (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAM109A; family with sequence similarity 109 member A; sesquipedalian-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1269,003,005 - 9,010,411 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha269,156,360 - 9,173,161 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0269,253,171 - 9,269,978 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1269,209,252 - 9,226,004 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0269,271,435 - 9,288,239 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0269,224,897 - 9,241,700 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PHETA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1269,003,005 - 9,010,411 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha269,156,360 - 9,173,161 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0269,253,171 - 9,269,978 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1269,209,252 - 9,226,004 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0269,271,435 - 9,288,239 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0269,224,897 - 9,241,700 (-)NCBIUU_Cfam_GSD_1.0
PHETA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812111,360,679 - 111,369,095 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12111,360,651 - 111,369,121 (-)EnsemblGRCh38hg38GRCh38
GRCh3712111,798,483 - 111,806,899 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612110,282,866 - 110,291,308 (-)NCBINCBI36Build 36hg18NCBI36
Celera12111,424,946 - 111,433,416 (-)NCBICelera
Cytogenetic Map12q24.12NCBI
HuRef12108,813,227 - 108,821,697 (-)NCBIHuRef
CHM1_112111,766,415 - 111,774,885 (-)NCBICHM1_1
T2T-CHM13v2.012111,341,175 - 111,349,591 (-)NCBIT2T-CHM13v2.0
Pheta1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395121,987,060 - 121,992,667 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5121,987,047 - 121,992,695 (+)EnsemblGRCm39 Ensembl
GRCm385121,848,997 - 121,854,604 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5121,848,984 - 121,854,632 (+)EnsemblGRCm38mm10GRCm38
MGSCv375122,299,037 - 122,304,608 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365122,109,645 - 122,115,216 (+)NCBIMGSCv36mm8
Celera5118,939,405 - 118,944,976 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.01NCBI
Pheta1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81240,372,553 - 40,378,321 (-)NCBIGRCr8
mRatBN7.21234,711,831 - 34,717,601 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1234,711,810 - 34,717,081 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,884,850 - 35,889,973 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01236,496,064 - 36,501,187 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,548,532 - 35,553,655 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01240,225,316 - 40,230,573 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,226,593 - 40,227,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01242,096,273 - 42,101,523 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41235,917,800 - 35,921,702 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11235,780,477 - 35,785,128 (-)NCBI
Celera1236,377,385 - 36,382,642 (-)NCBICelera
Cytogenetic Map12q16NCBI
Pheta1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554828,052,534 - 8,058,004 (-)NCBIChiLan1.0ChiLan1.0
PHETA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210119,421,903 - 119,430,569 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112119,418,831 - 119,426,948 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012108,928,091 - 108,936,858 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112112,323,498 - 112,332,138 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12112,325,501 - 112,328,545 (-)Ensemblpanpan1.1panPan2
Pheta1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118155,405,405 - 155,412,594 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365584,066,832 - 4,073,906 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHETA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1432,593,719 - 32,600,693 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11432,585,108 - 32,600,708 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21434,587,387 - 34,596,307 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHETA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111106,614,002 - 106,622,512 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11106,616,004 - 106,616,747 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037138,476,567 - 138,484,776 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pheta1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474720,771,674 - 20,779,254 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PHETA1
91 total Variants

Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014107831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038436682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038436683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038511598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038511599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038575090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038575091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038639278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038639279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005302320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005315183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005345402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005379160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005412988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_038436682   ⟹   XP_038292610
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0269,262,646 - 9,269,978 (-)NCBI
RefSeq Acc Id: XM_038436683   ⟹   XP_038292611
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0269,262,646 - 9,269,912 (-)NCBI
RefSeq Acc Id: XM_038459477   ⟹   XP_038315405
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha269,165,830 - 9,173,161 (-)NCBI
RefSeq Acc Id: XM_038511598   ⟹   XP_038367526
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1269,218,690 - 9,226,004 (-)NCBI
RefSeq Acc Id: XM_038511599   ⟹   XP_038367527
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1269,218,690 - 9,225,938 (-)NCBI
RefSeq Acc Id: XM_038575090   ⟹   XP_038431018
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0269,234,367 - 9,241,700 (-)NCBI
RefSeq Acc Id: XM_038575091   ⟹   XP_038431019
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0269,234,367 - 9,241,634 (-)NCBI
RefSeq Acc Id: XM_038639278   ⟹   XP_038495206
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0269,280,907 - 9,288,239 (-)NCBI
RefSeq Acc Id: XM_038639279   ⟹   XP_038495207
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0269,280,907 - 9,288,173 (-)NCBI
RefSeq Acc Id: XR_005302320
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0269,253,171 - 9,269,971 (-)NCBI
RefSeq Acc Id: XR_005315183
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha269,156,360 - 9,173,154 (-)NCBI
RefSeq Acc Id: XR_005345402
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1269,209,252 - 9,225,997 (-)NCBI
RefSeq Acc Id: XR_005379160
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0269,224,897 - 9,241,693 (-)NCBI
RefSeq Acc Id: XR_005412988
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0269,271,435 - 9,288,232 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038367526   ⟸   XM_038511598
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038367527   ⟸   XM_038511599
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038495206   ⟸   XM_038639278
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038495207   ⟸   XM_038639279
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038292610   ⟸   XM_038436682
- Peptide Label: isoform X1
- UniProtKB: A0A8C0P3E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038292611   ⟸   XM_038436683
- Peptide Label: isoform X2
- UniProtKB: A0A8I3S6Z6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315405   ⟸   XM_038459477
- Peptide Label: isoform X3
- UniProtKB: A0A8I3S6Z6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431018   ⟸   XM_038575090
- Peptide Label: isoform X1
- UniProtKB: A0A8C0P3E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431019   ⟸   XM_038575091
- Peptide Label: isoform X2
- UniProtKB: A0A8I3S6Z6 (UniProtKB/TrEMBL)
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00030022097 UniProtKB/TrEMBL
  ENSCAFG00845029033 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030040566.1 UniProtKB/TrEMBL
  ENSCAFT00845051358.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro Boi1/Boi2-like UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene FAM109A ENTREZGENE
PANTHER PTHR22902 UniProtKB/TrEMBL
  SESQUIPEDALIAN-1 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A8C0P3E4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S6Z6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:52931 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-06 PHETA1  PH domain containing endocytic trafficking adaptor 1  FAM109A  family with sequence similarity 109 member A  Symbol and/or name change 5135510 APPROVED