TMF1 (TATA element modulatory factor 1) - Rat Genome Database

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Gene: TMF1 (TATA element modulatory factor 1) Canis lupus familiaris
Analyze
Symbol: TMF1
Name: TATA element modulatory factor 1
RGD ID: 12383506
Description: ENCODES a protein that exhibits nuclear androgen receptor binding (inferred); nuclear receptor coactivator activity (inferred); INVOLVED IN acrosome assembly (ortholog); apoptotic process (ortholog); cellular response to organic cyclic compound (ortholog); ASSOCIATED WITH genetic disease (ortholog); polycystic ovary syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TATA element modulatory factor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12022,684,150 - 22,716,107 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2022,684,159 - 22,714,432 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2022,658,805 - 22,690,795 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02022,710,043 - 22,742,243 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2022,710,062 - 22,742,235 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12022,403,879 - 22,435,817 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02022,747,315 - 22,779,308 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02022,817,189 - 22,849,345 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202   PMID:37756605  


Genomics

Comparative Map Data
TMF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12022,684,150 - 22,716,107 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2022,684,159 - 22,714,432 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2022,658,805 - 22,690,795 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02022,710,043 - 22,742,243 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2022,710,062 - 22,742,235 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12022,403,879 - 22,435,817 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02022,747,315 - 22,779,308 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02022,817,189 - 22,849,345 (+)NCBIUU_Cfam_GSD_1.0
TMF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38369,019,827 - 69,052,333 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl369,019,827 - 69,052,339 (-)EnsemblGRCh38hg38GRCh38
GRCh37369,068,978 - 69,101,484 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36369,151,668 - 69,184,174 (-)NCBINCBI36Build 36hg18NCBI36
Build 34369,155,017 - 69,183,927NCBI
Celera368,997,084 - 69,029,590 (-)NCBICelera
Cytogenetic Map3p14.1NCBI
HuRef369,070,037 - 69,102,555 (-)NCBIHuRef
CHM1_1369,020,189 - 69,052,693 (-)NCBICHM1_1
T2T-CHM13v2.0369,056,599 - 69,089,119 (-)NCBIT2T-CHM13v2.0
Tmf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39697,128,911 - 97,156,107 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl697,129,958 - 97,156,083 (-)EnsemblGRCm39 Ensembl
GRCm38697,151,950 - 97,179,151 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl697,152,997 - 97,179,122 (-)EnsemblGRCm38mm10GRCm38
MGSCv37697,101,944 - 97,129,118 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36697,120,729 - 97,144,587 (-)NCBIMGSCv36mm8
Celera699,011,031 - 99,037,969 (-)NCBICelera
Cytogenetic Map6D3NCBI
cM Map644.89NCBI
Tmf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84131,316,630 - 131,345,666 (-)NCBIGRCr8
mRatBN7.24129,759,952 - 129,785,705 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4129,763,114 - 129,785,629 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4135,187,721 - 135,210,260 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04130,968,762 - 130,991,302 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04129,586,707 - 129,609,247 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04129,521,986 - 129,546,024 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4129,521,991 - 129,544,506 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04194,025,425 - 194,047,939 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44131,876,012 - 131,898,533 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14132,128,029 - 132,143,297 (-)NCBI
Celera4118,639,134 - 118,661,654 (-)NCBICelera
Cytogenetic Map4q34NCBI
Tmf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542118,810,199 - 18,837,761 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542118,810,199 - 18,837,767 (+)NCBIChiLan1.0ChiLan1.0
TMF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2268,970,671 - 69,009,943 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1368,977,647 - 69,014,709 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0368,955,866 - 68,988,353 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1370,322,814 - 70,355,433 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl370,322,814 - 70,355,460 (-)Ensemblpanpan1.1panPan2
Tmf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049421,577,538 - 1,602,016 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366031,577,486 - 1,602,250 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366031,577,519 - 1,602,022 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1350,444,256 - 50,477,291 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11350,442,017 - 50,477,363 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21355,527,055 - 55,558,194 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12230,048,269 - 30,078,600 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2230,045,685 - 30,078,414 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041136,713,836 - 136,746,704 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247733,587,753 - 3,618,089 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TMF1
449 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 14 3 5 8 8 10
Low 4 5 8 6 3 6 1 6 4 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000010573   ⟹   ENSCAFP00000009803
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2022,684,159 - 22,714,432 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000063869   ⟹   ENSCAFP00000058574
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2022,684,159 - 22,714,432 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000070241   ⟹   ENSCAFP00000066485
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2022,684,159 - 22,714,432 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000083702   ⟹   ENSCAFP00000065979
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2022,684,159 - 22,714,096 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845019113   ⟹   ENSCAFP00845014931
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2022,710,062 - 22,741,123 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845019168   ⟹   ENSCAFP00845014976
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2022,710,062 - 22,741,123 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845019198   ⟹   ENSCAFP00845014997
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2022,710,096 - 22,742,235 (+)Ensembl
RefSeq Acc Id: XM_005632274   ⟹   XP_005632331
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12022,684,150 - 22,716,107 (+)NCBI
Dog10K_Boxer_Tasha2022,658,805 - 22,690,795 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038427176   ⟹   XP_038283104
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02022,710,043 - 22,742,243 (+)NCBI
RefSeq Acc Id: XM_038502926   ⟹   XP_038358854
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12022,403,879 - 22,435,817 (+)NCBI
RefSeq Acc Id: XM_038565875   ⟹   XP_038421803
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02022,817,189 - 22,849,345 (+)NCBI
RefSeq Acc Id: XM_038629994   ⟹   XP_038485922
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02022,747,315 - 22,779,308 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005632331   ⟸   XM_005632274
- UniProtKB: A0A8C0MUU7 (UniProtKB/TrEMBL),   A0A8C0MZW0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000066485   ⟸   ENSCAFT00000070241
RefSeq Acc Id: ENSCAFP00000058574   ⟸   ENSCAFT00000063869
RefSeq Acc Id: ENSCAFP00000009803   ⟸   ENSCAFT00000010573
RefSeq Acc Id: ENSCAFP00000065979   ⟸   ENSCAFT00000083702
RefSeq Acc Id: XP_038358854   ⟸   XM_038502926
RefSeq Acc Id: XP_038485922   ⟸   XM_038629994
RefSeq Acc Id: XP_038283104   ⟸   XM_038427176
- UniProtKB: A0A8C0MUU7 (UniProtKB/TrEMBL),   A0A8C0MZW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038421803   ⟸   XM_038565875
- UniProtKB: A0A8C0MZW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845014997   ⟸   ENSCAFT00845019198
RefSeq Acc Id: ENSCAFP00845014931   ⟸   ENSCAFT00845019113
RefSeq Acc Id: ENSCAFP00845014976   ⟸   ENSCAFT00845019168
Protein Domains
TATA element modulatory factor 1 TATA binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006553 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030009407 UniProtKB/TrEMBL
  ENSCAFG00845010825 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000010573.5 UniProtKB/TrEMBL
  ENSCAFT00000063869.2 UniProtKB/TrEMBL
  ENSCAFT00000070241.2 UniProtKB/TrEMBL
  ENSCAFT00000083702.2 UniProtKB/TrEMBL
  ENSCAFT00030017405.1 UniProtKB/TrEMBL
  ENSCAFT00030017523.1 UniProtKB/TrEMBL
  ENSCAFT00030017699.1 UniProtKB/TrEMBL
  ENSCAFT00030017757.1 UniProtKB/TrEMBL
  ENSCAFT00845019113.1 UniProtKB/TrEMBL
  ENSCAFT00845019168.1 UniProtKB/TrEMBL
  ENSCAFT00845019198 ENTREZGENE
  ENSCAFT00845019198.1 UniProtKB/TrEMBL
InterPro TMF_DNA-bd UniProtKB/TrEMBL
  TMF_TATA-bd UniProtKB/TrEMBL
NCBI Gene TMF1 ENTREZGENE
PANTHER TATA ELEMENT MODULATORY FACTOR UniProtKB/TrEMBL
  TATA ELEMENT MODULATORY FACTOR TMF1 UniProtKB/TrEMBL
Pfam TMF_DNA_bd UniProtKB/TrEMBL
  TMF_TATA_bd UniProtKB/TrEMBL
UniProt A0A8C0MR04_CANLF UniProtKB/TrEMBL
  A0A8C0MUU7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MV39_CANLF UniProtKB/TrEMBL
  A0A8C0MZW0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N745_CANLF UniProtKB/TrEMBL
  A0A8I3NBI9_CANLF UniProtKB/TrEMBL
  A0A8I3NGC0_CANLF UniProtKB/TrEMBL
  A0A8P0N954_CANLF UniProtKB/TrEMBL
  A0A8P0PF03_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0PEG4 UniProtKB/TrEMBL
VGNC ID VGNC:47620 ENTREZGENE