ASB7 (ankyrin repeat and SOCS box containing 7) - Rat Genome Database

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Gene: ASB7 (ankyrin repeat and SOCS box containing 7) Canis lupus familiaris
Analyze
Symbol: ASB7
Name: ankyrin repeat and SOCS box containing 7
RGD ID: 12382530
Description: ENCODES a protein that exhibits transcription cis-regulatory region binding (inferred); INVOLVED IN intracellular signal transduction (inferred); positive regulation of transcription by RNA polymerase II (inferred); protein ubiquitination (inferred); ASSOCIATED WITH chromosome 15q26-qter deletion syndrome (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ankyrin repeat and SOCS box protein 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1340,365,515 - 40,415,345 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl340,320,391 - 40,414,671 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha343,056,940 - 43,106,762 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0340,765,981 - 40,815,813 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl340,765,986 - 40,815,776 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1340,299,788 - 40,349,605 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0340,530,394 - 40,580,210 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0340,737,640 - 40,787,467 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ASB7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1340,365,515 - 40,415,345 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl340,320,391 - 40,414,671 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha343,056,940 - 43,106,762 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0340,765,981 - 40,815,813 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl340,765,986 - 40,815,776 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1340,299,788 - 40,349,605 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0340,530,394 - 40,580,210 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0340,737,640 - 40,787,467 (-)NCBIUU_Cfam_GSD_1.0
ASB7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3815100,602,589 - 100,651,701 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl15100,602,589 - 100,651,701 (+)EnsemblGRCh38hg38GRCh38
GRCh3715101,142,794 - 101,191,906 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361598,960,358 - 99,007,174 (+)NCBINCBI36Build 36hg18NCBI36
Celera1577,556,003 - 77,605,160 (+)NCBICelera
Cytogenetic Map15q26.3NCBI
HuRef1577,264,124 - 77,313,303 (+)NCBIHuRef
CHM1_115100,983,741 - 101,032,887 (+)NCBICHM1_1
T2T-CHM13v2.01598,357,248 - 98,406,286 (+)NCBIT2T-CHM13v2.0
Asb7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39766,294,220 - 66,339,601 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl766,294,313 - 66,339,344 (-)EnsemblGRCm39 Ensembl
GRCm38766,644,565 - 66,689,879 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl766,644,565 - 66,689,596 (-)EnsemblGRCm38mm10GRCm38
MGSCv37773,789,451 - 73,834,447 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36766,526,736 - 66,568,424 (-)NCBIMGSCv36mm8
Celera764,094,087 - 64,139,864 (-)NCBICelera
Cytogenetic Map7CNCBI
cM Map736.03NCBI
Asb7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81129,621,462 - 129,677,788 (-)NCBIGRCr8
mRatBN7.21120,222,835 - 120,267,411 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1120,222,745 - 120,267,282 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1128,223,699 - 128,265,296 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01135,395,133 - 135,436,728 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01128,199,488 - 128,240,900 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,545,671 - 127,599,257 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,554,785 - 127,599,257 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01128,623,601 - 128,674,470 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41121,091,586 - 121,142,773 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11121,179,169 - 121,210,981 (-)NCBI
Celera1112,419,585 - 112,470,051 (-)NCBICelera
Cytogenetic Map1q22NCBI
Asb7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541627,610,011 - 27,649,356 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541627,610,011 - 27,649,186 (+)NCBIChiLan1.0ChiLan1.0
ASB7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21690,194,669 - 90,243,989 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11593,894,996 - 93,944,336 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01579,328,868 - 79,378,039 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11598,616,797 - 98,734,650 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1598,616,797 - 98,666,094 (+)Ensemblpanpan1.1panPan2
Asb7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640143,128,581 - 143,165,827 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364833,168,137 - 3,205,880 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364833,165,577 - 3,205,878 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASB7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1139,191,572 - 139,240,185 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11139,191,407 - 139,240,206 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21155,395,977 - 155,444,625 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ASB7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12919,065,756 - 19,115,156 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2919,075,293 - 19,115,216 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605927,428,775 - 27,478,213 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asb7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247684,083,190 - 4,122,705 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247684,083,278 - 4,122,706 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ASB7
372 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 5 22 6 6 6 6 4 12 8 10 6
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000016975   ⟹   ENSCAFP00000015703
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl340,368,660 - 40,414,671 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000090406   ⟹   ENSCAFP00000062769
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl340,320,391 - 40,414,671 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845001960   ⟹   ENSCAFP00845001539
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl340,765,986 - 40,815,776 (-)Ensembl
RefSeq Acc Id: XM_038471735   ⟹   XP_038327663
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1340,299,788 - 40,349,605 (-)NCBI
RefSeq Acc Id: XM_038532661   ⟹   XP_038388589
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0340,737,640 - 40,787,467 (-)NCBI
RefSeq Acc Id: XM_038596966   ⟹   XP_038452894
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0340,530,394 - 40,580,210 (-)NCBI
RefSeq Acc Id: XM_038661176   ⟹   XP_038517104
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0340,765,981 - 40,815,813 (-)NCBI
RefSeq Acc Id: XM_545824   ⟹   XP_545824
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1340,365,515 - 40,415,345 (-)NCBI
Dog10K_Boxer_Tasha343,056,940 - 43,106,762 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_545824   ⟸   XM_545824
- UniProtKB: A0A8C0M0M5 (UniProtKB/TrEMBL),   A0A8C0L2K2 (UniProtKB/TrEMBL),   A0A8I3MDK9 (UniProtKB/TrEMBL),   A0A8C0RAA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000062769   ⟸   ENSCAFT00000090406
RefSeq Acc Id: ENSCAFP00000015703   ⟸   ENSCAFT00000016975
RefSeq Acc Id: XP_038327663   ⟸   XM_038471735
RefSeq Acc Id: XP_038452894   ⟸   XM_038596966
RefSeq Acc Id: XP_038517104   ⟸   XM_038661176
- UniProtKB: A0A8C0M0M5 (UniProtKB/TrEMBL),   A0A8C0L2K2 (UniProtKB/TrEMBL),   A0A8I3MDK9 (UniProtKB/TrEMBL),   A0A8C0RAA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038388589   ⟸   XM_038532661
- UniProtKB: A0A8C0L2K2 (UniProtKB/TrEMBL),   A0A8C0M0M5 (UniProtKB/TrEMBL),   A0A8C0RAA0 (UniProtKB/TrEMBL),   A0A8I3MDK9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845001539   ⟸   ENSCAFT00845001960
Protein Domains
SOCS box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010679 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030001475 UniProtKB/TrEMBL
  ENSCAFG00040023047 UniProtKB/TrEMBL
  ENSCAFG00845001149 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000016975.5 UniProtKB/TrEMBL
  ENSCAFT00030002629.1 UniProtKB/TrEMBL
  ENSCAFT00030002634.1 UniProtKB/TrEMBL
  ENSCAFT00040042834.1 UniProtKB/TrEMBL
  ENSCAFT00845001960 ENTREZGENE
  ENSCAFT00845001960.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  SOCS box UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  ASB7_SOCS UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
  SOCS_box-like_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:488707 UniProtKB/TrEMBL
NCBI Gene ASB7 ENTREZGENE
PANTHER ANK_REP_REGION DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  ANKYRIN REPEAT PROTEIN UniProtKB/TrEMBL
  MYOTROPHIN UniProtKB/TrEMBL
  MYOTROPHIN-RELATED UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
Superfamily-SCOP SSF158235 UniProtKB/TrEMBL
  SSF48403 UniProtKB/TrEMBL
UniProt A0A8C0L2K2 ENTREZGENE
  A0A8C0M0M5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RAA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MDK9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:38167 ENTREZGENE