GATA5 (GATA binding protein 5) - Rat Genome Database

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Gene: GATA5 (GATA binding protein 5) Canis lupus familiaris
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Symbol: GATA5
Name: GATA binding protein 5
RGD ID: 12382402
Description: ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (inferred); DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN cardiac jelly development (ortholog); cellular response to BMP stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); ASSOCIATED WITH acute myocardial infarction (ortholog); aortic valve disease 1 (ortholog); ARTERIAL DISSECTION (ortholog); FOUND IN chromatin (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor GATA-5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12446,417,404 - 46,427,617 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2446,417,391 - 46,429,858 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2445,668,394 - 45,678,477 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02447,288,132 - 47,298,276 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2447,288,119 - 47,298,250 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12446,389,267 - 46,399,377 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02446,512,623 - 46,522,731 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,266,944 - 47,277,059 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GATA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12446,417,404 - 46,427,617 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2446,417,391 - 46,429,858 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2445,668,394 - 45,678,477 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02447,288,132 - 47,298,276 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2447,288,119 - 47,298,250 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12446,389,267 - 46,399,377 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02446,512,623 - 46,522,731 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,266,944 - 47,277,059 (-)NCBIUU_Cfam_GSD_1.0
GATA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382062,463,497 - 62,475,995 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2062,463,497 - 62,475,995 (-)EnsemblGRCh38hg38GRCh38
GRCh372061,038,553 - 61,051,051 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362060,471,948 - 60,484,421 (-)NCBINCBI36Build 36hg18NCBI36
Build 342060,471,948 - 60,484,421NCBI
Celera2057,773,808 - 57,786,309 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2057,816,177 - 57,828,255 (-)NCBIHuRef
CHM1_12060,939,508 - 60,951,981 (-)NCBICHM1_1
T2T-CHM13v2.02064,260,442 - 64,272,970 (-)NCBIT2T-CHM13v2.0
Gata5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392179,966,881 - 179,977,296 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2179,966,926 - 179,976,492 (-)EnsemblGRCm39 Ensembl
GRCm382180,325,088 - 180,335,503 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2180,325,133 - 180,334,699 (-)EnsemblGRCm38mm10GRCm38
MGSCv372180,059,793 - 180,069,384 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362180,254,541 - 180,264,081 (-)NCBIMGSCv36mm8
Celera2184,410,037 - 184,419,626 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2102.85NCBI
Gata5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83187,796,140 - 187,804,327 (-)NCBIGRCr8
mRatBN7.23167,418,563 - 167,426,751 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3167,418,565 - 167,426,751 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3171,795,150 - 171,803,330 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03180,754,236 - 180,762,416 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03177,419,481 - 177,427,668 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03175,701,278 - 175,709,465 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3175,701,280 - 175,709,465 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03181,406,297 - 181,414,484 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43169,385,321 - 169,393,508 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3165,153,452 - 165,161,639 (+)NCBICelera
Cytogenetic Map3q43NCBI
Gata5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555281,595,231 - 1,604,979 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555281,595,231 - 1,604,979 (+)NCBIChiLan1.0ChiLan1.0
GATA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22168,248,336 - 68,260,825 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12068,241,456 - 68,253,945 (-)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl2060,148,359 - 60,158,886 (-)Ensemblpanpan1.1panPan2
Gata5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640194,607,468 - 194,616,966 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651410,061,675 - 10,070,541 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651410,061,675 - 10,070,541 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GATA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1761,824,899 - 61,834,267 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11761,824,891 - 61,834,742 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21769,233,783 - 69,243,866 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GATA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121,756,911 - 1,769,452 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21,757,420 - 1,768,143 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605049,698,289 - 49,710,923 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gata5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474128,310,201 - 28,321,095 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474128,310,679 - 28,322,209 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GATA5
284 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 1
Low 1 11 6 6 6 6 3 5
Below cutoff 3 5 10 5 6 2 2

Sequence


RefSeq Acc Id: ENSCAFT00000020138   ⟹   ENSCAFP00000018678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2446,417,391 - 46,429,858 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000061115   ⟹   ENSCAFP00000059793
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2446,417,391 - 46,429,858 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845030456   ⟹   ENSCAFP00845023888
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2447,288,119 - 47,298,250 (-)Ensembl
RefSeq Acc Id: XM_038434287   ⟹   XP_038290215
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02447,288,132 - 47,298,276 (-)NCBI
RefSeq Acc Id: XM_038509448   ⟹   XP_038365376
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12446,389,267 - 46,399,377 (-)NCBI
RefSeq Acc Id: XM_038572804   ⟹   XP_038428732
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02447,266,944 - 47,277,059 (-)NCBI
RefSeq Acc Id: XM_038637081   ⟹   XP_038493009
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02446,512,623 - 46,522,731 (-)NCBI
RefSeq Acc Id: XM_543086   ⟹   XP_543086
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12446,417,404 - 46,427,617 (-)NCBI
Dog10K_Boxer_Tasha2445,668,394 - 45,678,477 (-)NCBI
Sequence:
RefSeq Acc Id: XP_543086   ⟸   XM_543086
- UniProtKB: A0A8C0JHZ7 (UniProtKB/TrEMBL),   A0A8C0N6R0 (UniProtKB/TrEMBL),   A0A8I3RZQ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000018678   ⟸   ENSCAFT00000020138
RefSeq Acc Id: ENSCAFP00000059793   ⟸   ENSCAFT00000061115
RefSeq Acc Id: XP_038365376   ⟸   XM_038509448
RefSeq Acc Id: XP_038493009   ⟸   XM_038637081
RefSeq Acc Id: XP_038290215   ⟸   XM_038434287
- UniProtKB: A0A8C0JHZ7 (UniProtKB/TrEMBL),   A0A8C0N6R0 (UniProtKB/TrEMBL),   A0A8I3RZQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038428732   ⟸   XM_038572804
- UniProtKB: A0A8C0JHZ7 (UniProtKB/TrEMBL),   A0A8C0N6R0 (UniProtKB/TrEMBL),   A0A8I3RZQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845023888   ⟸   ENSCAFT00845030456
Protein Domains
GATA-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012709 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030012418 UniProtKB/TrEMBL
  ENSCAFG00845017212 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020138.6 UniProtKB/TrEMBL
  ENSCAFT00030023039.1 UniProtKB/TrEMBL
  ENSCAFT00845030456 ENTREZGENE
  ENSCAFT00845030456.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.50.10 UniProtKB/TrEMBL
InterPro GATA_N UniProtKB/TrEMBL
  TF_GATA_4/5/6 UniProtKB/TrEMBL
  Transcription_factor_GATA UniProtKB/TrEMBL
  Znf_GATA UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/TrEMBL
KEGG Report cfa:485961 UniProtKB/TrEMBL
NCBI Gene GATA5 ENTREZGENE
PANTHER PTHR10071 UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR GATA-5 UniProtKB/TrEMBL
Pfam GATA UniProtKB/TrEMBL
  GATA-N UniProtKB/TrEMBL
PIRSF TF_GATA_4/5/6 UniProtKB/TrEMBL
PRINTS GATAZNFINGER UniProtKB/TrEMBL
PROSITE GATA_ZN_FINGER_1 UniProtKB/TrEMBL
  GATA_ZN_FINGER_2 UniProtKB/TrEMBL
SMART ZnF_GATA UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A0A8C0JHZ7 ENTREZGENE
  A0A8C0N6R0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RZQ7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:41124 ENTREZGENE