FGFBP1 (fibroblast growth factor binding protein 1) - Rat Genome Database

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Gene: FGFBP1 (fibroblast growth factor binding protein 1) Canis lupus familiaris
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Symbol: FGFBP1
Name: fibroblast growth factor binding protein 1
RGD ID: 12377426
Description: ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); INVOLVED IN cell-cell signaling (ortholog); fibroblast growth factor receptor signaling pathway (ortholog); myoblast proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); Joubert syndrome 1 (ortholog); FOUND IN cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fibroblast growth factor-binding protein 1; LOC488818
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1364,447,441 - 64,450,529 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl364,449,411 - 64,450,178 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha366,965,564 - 66,968,653 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0364,926,048 - 64,929,145 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl364,926,126 - 64,929,135 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1364,415,415 - 64,418,508 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0364,619,531 - 64,622,601 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0364,979,762 - 64,982,848 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FGFBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1364,447,441 - 64,450,529 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl364,449,411 - 64,450,178 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha366,965,564 - 66,968,653 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0364,926,048 - 64,929,145 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl364,926,126 - 64,929,135 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1364,415,415 - 64,418,508 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0364,619,531 - 64,622,601 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0364,979,762 - 64,982,848 (+)NCBIUU_Cfam_GSD_1.0
FGFBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38415,935,577 - 15,938,740 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl415,935,577 - 15,938,740 (-)EnsemblGRCh38hg38GRCh38
GRCh37415,937,200 - 15,940,363 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36415,546,290 - 15,549,069 (-)NCBINCBI36Build 36hg18NCBI36
Build 34415,613,462 - 15,616,240NCBI
Celera416,401,736 - 16,404,515 (-)NCBICelera
Cytogenetic Map4p15.32NCBI
HuRef415,286,779 - 15,289,950 (-)NCBIHuRef
CHM1_1415,934,975 - 15,938,146 (-)NCBICHM1_1
T2T-CHM13v2.0415,917,258 - 15,920,421 (-)NCBIT2T-CHM13v2.0
Fgfbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39544,136,200 - 44,139,173 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl544,136,200 - 44,139,121 (-)EnsemblGRCm39 Ensembl
GRCm38543,978,858 - 43,981,828 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl543,978,858 - 43,981,779 (-)EnsemblGRCm38mm10GRCm38
MGSCv37544,370,099 - 44,373,001 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36544,267,108 - 44,270,010 (-)NCBIMGSCv36mm8
Celera541,407,787 - 41,410,689 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map523.95NCBI
Fgfbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81471,316,171 - 71,319,965 (+)NCBIGRCr8
mRatBN7.21467,103,686 - 67,107,492 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1467,104,545 - 67,107,496 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1471,512,780 - 71,513,862 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01472,786,550 - 72,787,632 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01469,223,205 - 69,224,287 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01471,647,429 - 71,650,359 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1471,649,274 - 71,650,354 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01471,677,999 - 71,680,898 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41472,242,271 - 72,243,353 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11472,244,661 - 72,245,742 (+)NCBI
Celera1466,064,463 - 66,065,545 (+)NCBICelera
Cytogenetic Map14q21NCBI
Fgfbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554808,088,670 - 8,091,882 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554808,088,670 - 8,091,882 (+)NCBIChiLan1.0ChiLan1.0
FGFBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2316,215,547 - 16,218,445 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1416,413,185 - 16,416,084 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0410,374,303 - 10,377,210 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1415,671,157 - 15,674,063 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl415,671,516 - 15,672,220 (-)Ensemblpanpan1.1panPan2
LOC101976958
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528558,328,351 - 58,331,287 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647712,030,140 - 12,032,626 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGFBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl811,186,368 - 11,189,241 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1811,186,360 - 11,189,317 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2810,836,810 - 10,839,763 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGFBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12734,274,489 - 34,277,672 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2734,276,611 - 34,277,315 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604781,008,181 - 81,011,393 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in FGFBP1
46 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 2 6 6 6
Low 5 7 1 1 5 4
Below cutoff 13 5 6 5 1 9 8

Sequence


RefSeq Acc Id: ENSCAFT00000024255   ⟹   ENSCAFP00000022519
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl364,449,411 - 64,450,178 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845002207   ⟹   ENSCAFP00845001744
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl364,926,126 - 64,929,135 (+)Ensembl
RefSeq Acc Id: XM_005618560   ⟹   XP_005618617
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1364,447,441 - 64,450,529 (+)NCBI
Dog10K_Boxer_Tasha366,965,564 - 66,968,653 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038471187   ⟹   XP_038327115
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1364,415,415 - 64,418,508 (+)NCBI
RefSeq Acc Id: XM_038532107   ⟹   XP_038388035
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0364,979,762 - 64,982,848 (+)NCBI
RefSeq Acc Id: XM_038596363   ⟹   XP_038452291
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0364,619,531 - 64,622,601 (+)NCBI
RefSeq Acc Id: XM_038660559   ⟹   XP_038516487
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0364,926,048 - 64,929,145 (+)NCBI
RefSeq Acc Id: XP_005618617   ⟸   XM_005618560
- UniProtKB: A0A8P0SJZ4 (UniProtKB/TrEMBL),   A0A8C0SCP9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000022519   ⟸   ENSCAFT00000024255
RefSeq Acc Id: XP_038327115   ⟸   XM_038471187
RefSeq Acc Id: XP_038452291   ⟸   XM_038596363
RefSeq Acc Id: XP_038516487   ⟸   XM_038660559
- UniProtKB: A0A8I3MH10 (UniProtKB/TrEMBL),   A0A8C0KER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038388035   ⟸   XM_038532107
- UniProtKB: A0A8C0SCP9 (UniProtKB/TrEMBL),   A0A8P0SJZ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845001744   ⟸   ENSCAFT00845002207


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015272 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002699 UniProtKB/TrEMBL
  ENSCAFG00040012148 UniProtKB/TrEMBL
  ENSCAFG00845001279 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000024255.5 UniProtKB/TrEMBL
  ENSCAFT00030005014.1 UniProtKB/TrEMBL
  ENSCAFT00040022415.1 UniProtKB/TrEMBL
  ENSCAFT00845002207 ENTREZGENE
  ENSCAFT00845002207.1 UniProtKB/TrEMBL
InterPro FGF1-bd UniProtKB/TrEMBL
KEGG Report cfa:488818 UniProtKB/TrEMBL
NCBI Gene LOC488818 ENTREZGENE
PANTHER FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 1 UniProtKB/TrEMBL
  PTHR15258 UniProtKB/TrEMBL
Pfam FGF-BP1 UniProtKB/TrEMBL
UniProt A0A8C0KER1 ENTREZGENE
  A0A8C0SCP9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MH10 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SJZ4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:49742 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-12 FGFBP1  fibroblast growth factor binding protein 1  LOC488818  fibroblast growth factor-binding protein 1  Symbol and/or name change 5135510 APPROVED