ESPNL (espin like) - Rat Genome Database

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Gene: ESPNL (espin like) Canis lupus familiaris
Analyze
Symbol: ESPNL
Name: espin like
RGD ID: 12376405
Description: ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); INVOLVED IN actin filament bundle assembly (inferred); sensory perception of sound (inferred); ASSOCIATED WITH Bethlem Myopathy 1A (ortholog); chromosome 2q37 deletion syndrome (ortholog); D-2-hydroxyglutaric aciduria 1 (ortholog); FOUND IN stereocilium tip (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: espin-like; espin-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12548,609,340 - 48,634,397 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2549,105,311 - 49,132,935 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02548,995,197 - 49,023,042 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2548,995,158 - 49,021,659 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12548,870,291 - 48,897,694 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02548,658,916 - 48,686,318 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02548,891,219 - 48,918,851 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ESPNL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12548,609,340 - 48,634,397 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2549,105,311 - 49,132,935 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02548,995,197 - 49,023,042 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2548,995,158 - 49,021,659 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12548,870,291 - 48,897,694 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02548,658,916 - 48,686,318 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02548,891,219 - 48,918,851 (+)NCBIUU_Cfam_GSD_1.0
ESPNL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,100,340 - 238,133,287 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,100,340 - 238,133,287 (+)EnsemblGRCh38hg38GRCh38
GRCh372239,008,981 - 239,041,928 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,673,690 - 238,706,667 (+)NCBINCBI36Build 36hg18NCBI36
Celera2232,721,894 - 232,754,471 (+)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2230,800,976 - 230,833,055 (+)NCBIHuRef
CHM1_12239,014,636 - 239,047,034 (+)NCBICHM1_1
T2T-CHM13v2.02238,590,236 - 238,623,038 (+)NCBIT2T-CHM13v2.0
Espnl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39191,249,845 - 91,277,130 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl191,249,797 - 91,276,028 (+)EnsemblGRCm39 Ensembl
GRCm38191,322,075 - 91,348,303 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl191,322,075 - 91,348,306 (+)EnsemblGRCm38mm10GRCm38
MGSCv37193,218,652 - 93,244,880 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36193,152,481 - 93,178,709 (+)NCBIMGSCv36mm8
Celera194,259,186 - 94,285,436 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map146.08NCBI
Espnl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8999,358,907 - 99,385,439 (+)NCBIGRCr8
mRatBN7.2991,912,038 - 91,936,803 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl991,912,049 - 91,935,292 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9100,338,818 - 100,362,060 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09105,474,578 - 105,497,820 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09103,838,173 - 103,861,427 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0998,459,175 - 98,484,930 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl998,460,177 - 98,483,419 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0998,136,139 - 98,161,479 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4990,547,266 - 90,570,761 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera989,453,359 - 89,476,315 (+)NCBICelera
Cytogenetic Map9q36NCBI
Espnl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555422,430,712 - 2,453,361 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555422,430,610 - 2,453,738 (-)NCBIChiLan1.0ChiLan1.0
ESPNL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213140,731,545 - 140,764,431 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B140,746,512 - 140,779,398 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B125,331,809 - 125,364,719 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B244,182,671 - 244,214,248 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B244,182,781 - 244,214,009 (+)Ensemblpanpan1.1panPan2
Espnl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303190,558,612 - 190,590,062 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936525352,389 - 380,214 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936525352,389 - 380,214 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESPNL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15137,675,710 - 137,706,662 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115137,674,867 - 137,706,968 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215152,084,342 - 152,114,957 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ESPNL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110124,122,495 - 124,152,355 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10124,123,379 - 124,152,127 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604075,265,583 - 75,295,437 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Espnl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248473,279,555 - 3,298,589 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248473,279,022 - 3,299,321 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ESPNL
520 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00845052528   ⟹   ENSCAFP00845041218
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2548,995,158 - 49,021,659 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845052541   ⟹   ENSCAFP00845041230
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2548,995,792 - 49,021,659 (+)Ensembl
RefSeq Acc Id: XM_038435926   ⟹   XP_038291854
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02548,995,197 - 49,023,042 (+)NCBI
RefSeq Acc Id: XM_038458771   ⟹   XP_038314699
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2549,105,311 - 49,132,935 (+)NCBI
RefSeq Acc Id: XM_038510848   ⟹   XP_038366776
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12548,870,291 - 48,897,694 (+)NCBI
RefSeq Acc Id: XM_038574347   ⟹   XP_038430275
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02548,891,219 - 48,918,851 (+)NCBI
RefSeq Acc Id: XM_038638584   ⟹   XP_038494512
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02548,658,916 - 48,686,318 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038366776   ⟸   XM_038510848
RefSeq Acc Id: XP_038494512   ⟸   XM_038638584
RefSeq Acc Id: XP_038291854   ⟸   XM_038435926
- UniProtKB: A0A8I3Q0W0 (UniProtKB/TrEMBL),   A0A8P0PJ49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038314699   ⟸   XM_038458771
- UniProtKB: A0A8I3Q0W0 (UniProtKB/TrEMBL),   A0A8P0PJ49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038430275   ⟸   XM_038574347
RefSeq Acc Id: ENSCAFP00845041230   ⟸   ENSCAFT00845052541
RefSeq Acc Id: ENSCAFP00845041218   ⟸   ENSCAFT00845052528


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000058917 UniProtKB/TrEMBL
  ENSCAFG00845029664 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000100398.1 UniProtKB/TrEMBL
  ENSCAFT00000107211.1 UniProtKB/TrEMBL
  ENSCAFT00845052528 ENTREZGENE
  ENSCAFT00845052528.1 UniProtKB/TrEMBL
  ENSCAFT00845052541.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
NCBI Gene ESPNL ENTREZGENE
PANTHER ESPIN UniProtKB/TrEMBL
  ESPIN-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A8I3Q0W0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q0X1_CANLF UniProtKB/TrEMBL
  A0A8P0PJ49 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TJB8_CANLF UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-20 ESPNL  espin like    espin-like  Symbol and/or name change 5135510 APPROVED