WASHC5 (WASH complex subunit 5) - Rat Genome Database

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Gene: WASHC5 (WASH complex subunit 5) Canis lupus familiaris
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Symbol: WASHC5
Name: WASH complex subunit 5
RGD ID: 12374340
Description: INVOLVED IN endosomal transport (ortholog); lysosome organization (ortholog); positive regulation of neuron projection development (ortholog); PARTICIPATES IN retromer-mediated pathway; ASSOCIATED WITH genetic disease (ortholog); hereditary spastic paraplegia (ortholog); hereditary spastic paraplegia 10 (ortholog); FOUND IN neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: KIAA0196; WASH complex subunit strumpellin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11323,019,422 - 23,078,073 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1323,019,636 - 23,078,280 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1322,983,619 - 23,042,271 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01323,361,232 - 23,419,922 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1323,361,234 - 23,419,935 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11323,081,984 - 23,140,611 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01323,191,178 - 23,249,843 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01323,434,176 - 23,492,905 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
early endosome  (IEA)
endosome  (IBA,IEA)
neuronal cell body  (ISO)
WASH complex  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
WASHC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11323,019,422 - 23,078,073 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1323,019,636 - 23,078,280 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1322,983,619 - 23,042,271 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01323,361,232 - 23,419,922 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1323,361,234 - 23,419,935 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11323,081,984 - 23,140,611 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01323,191,178 - 23,249,843 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01323,434,176 - 23,492,905 (-)NCBIUU_Cfam_GSD_1.0
WASHC5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388125,024,260 - 125,091,792 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8125,024,260 - 125,091,819 (-)EnsemblGRCh38hg38GRCh38
GRCh378126,036,502 - 126,104,034 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368126,105,684 - 126,173,243 (-)NCBINCBI36Build 36hg18NCBI36
Celera8122,225,172 - 122,293,224 (-)NCBICelera
Cytogenetic Map8q24.13NCBI
HuRef8121,360,288 - 121,427,855 (-)NCBIHuRef
CHM1_18126,077,126 - 126,144,676 (-)NCBICHM1_1
T2T-CHM13v2.08126,158,081 - 126,225,631 (-)NCBIT2T-CHM13v2.0
Washc5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391559,203,712 - 59,246,043 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1559,203,846 - 59,246,016 (-)EnsemblGRCm39 Ensembl
GRCm381559,331,863 - 59,374,194 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1559,331,997 - 59,374,167 (-)EnsemblGRCm38mm10GRCm38
MGSCv371559,163,552 - 59,205,707 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361559,161,678 - 59,203,833 (-)NCBIMGSCv36mm8
Celera1560,862,638 - 60,905,171 (-)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1525.17NCBI
Washc5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8792,773,625 - 92,825,532 (-)NCBIGRCr8
mRatBN7.2790,884,192 - 90,936,096 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl790,884,197 - 90,936,103 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx792,774,029 - 92,825,985 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0794,975,207 - 95,027,170 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0794,802,520 - 94,854,454 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0799,625,379 - 99,677,237 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl799,625,619 - 99,677,268 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07100,212,544 - 100,263,519 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4796,112,349 - 96,169,399 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera787,646,862 - 87,697,773 (-)NCBICelera
Cytogenetic Map7q33NCBI
Washc5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955461145,993 - 199,903 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955461145,993 - 199,274 (-)NCBIChiLan1.0ChiLan1.0
WASHC5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27142,447,027 - 142,514,855 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18117,958,154 - 118,026,003 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08121,710,118 - 121,777,977 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18124,461,424 - 124,529,262 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8124,461,424 - 124,529,262 (-)Ensemblpanpan1.1panPan2
Washc5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530315,241,282 - 15,299,433 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647022,667,127 - 22,725,749 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647022,667,354 - 22,725,538 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WASHC5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl414,598,150 - 14,668,313 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1414,598,133 - 14,667,535 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2415,149,906 - 15,246,609 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WASHC5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18119,612,921 - 119,679,058 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8119,611,210 - 119,668,885 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603920,495,821 - 20,567,260 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Washc5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473530,166,623 - 30,223,404 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473530,166,617 - 30,223,404 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in WASHC5
633 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000001638   ⟹   ENSCAFP00000001505
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1323,019,636 - 23,078,280 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000070146   ⟹   ENSCAFP00000051721
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1323,019,636 - 23,078,280 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845021590   ⟹   ENSCAFP00845016965
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1323,361,234 - 23,419,935 (-)Ensembl
RefSeq Acc Id: XM_022426700   ⟹   XP_022282408
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11323,019,422 - 23,076,126 (-)NCBI
Dog10K_Boxer_Tasha1322,983,619 - 23,042,153 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038493233   ⟹   XP_038349161
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11323,081,984 - 23,140,493 (-)NCBI
RefSeq Acc Id: XM_038493234   ⟹   XP_038349162
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11323,081,984 - 23,140,611 (-)NCBI
RefSeq Acc Id: XM_038555499   ⟹   XP_038411427
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01323,434,176 - 23,492,787 (-)NCBI
RefSeq Acc Id: XM_038555500   ⟹   XP_038411428
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01323,434,176 - 23,492,905 (-)NCBI
RefSeq Acc Id: XM_038619398   ⟹   XP_038475326
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01323,191,178 - 23,249,725 (-)NCBI
RefSeq Acc Id: XM_038619399   ⟹   XP_038475327
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01323,191,178 - 23,249,843 (-)NCBI
RefSeq Acc Id: XM_038685006   ⟹   XP_038540934
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01323,361,232 - 23,419,804 (-)NCBI
RefSeq Acc Id: XM_038685007   ⟹   XP_038540935
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01323,361,232 - 23,419,922 (-)NCBI
RefSeq Acc Id: XM_532327   ⟹   XP_532327
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11323,019,422 - 23,078,073 (-)NCBI
Dog10K_Boxer_Tasha1322,983,619 - 23,042,271 (-)NCBI
Sequence:
RefSeq Acc Id: XP_532327   ⟸   XM_532327
- UniProtKB: A0A8C0K0L2 (UniProtKB/TrEMBL),   A0A8C0MVQ7 (UniProtKB/TrEMBL),   A0A8I3NNA7 (UniProtKB/TrEMBL),   A0A8C0SUL4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022282408   ⟸   XM_022426700
- UniProtKB: A0A8C0K0L2 (UniProtKB/TrEMBL),   A0A8C0MVQ7 (UniProtKB/TrEMBL),   A0A8I3NNA7 (UniProtKB/TrEMBL),   A0A8C0SUL4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000001505   ⟸   ENSCAFT00000001638
Ensembl Acc Id: ENSCAFP00000051721   ⟸   ENSCAFT00000070146
RefSeq Acc Id: XP_038349162   ⟸   XM_038493234
RefSeq Acc Id: XP_038349161   ⟸   XM_038493233
RefSeq Acc Id: XP_038475327   ⟸   XM_038619399
RefSeq Acc Id: XP_038475326   ⟸   XM_038619398
RefSeq Acc Id: XP_038540935   ⟸   XM_038685007
- UniProtKB: A0A8C0K0L2 (UniProtKB/TrEMBL),   A0A8C0MVQ7 (UniProtKB/TrEMBL),   A0A8I3NNA7 (UniProtKB/TrEMBL),   A0A8C0SUL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038540934   ⟸   XM_038685006
- UniProtKB: A0A8C0K0L2 (UniProtKB/TrEMBL),   A0A8C0MVQ7 (UniProtKB/TrEMBL),   A0A8I3NNA7 (UniProtKB/TrEMBL),   A0A8C0SUL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038411428   ⟸   XM_038555500
- UniProtKB: A0A8C0SUL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038411427   ⟸   XM_038555499
- UniProtKB: A0A8C0SUL4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845016965   ⟸   ENSCAFT00845021590


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001070 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030009396 UniProtKB/TrEMBL
  ENSCAFG00040016335 UniProtKB/TrEMBL
  ENSCAFG00845012127 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000001638.5 UniProtKB/TrEMBL
  ENSCAFT00030017468.1 UniProtKB/TrEMBL
  ENSCAFT00030017651.1 UniProtKB/TrEMBL
  ENSCAFT00030017832.1 UniProtKB/TrEMBL
  ENSCAFT00030018086.1 UniProtKB/TrEMBL
  ENSCAFT00030018287.1 UniProtKB/TrEMBL
  ENSCAFT00040030126.1 UniProtKB/TrEMBL
  ENSCAFT00040030298.1 UniProtKB/TrEMBL
  ENSCAFT00040030492.1 UniProtKB/TrEMBL
  ENSCAFT00040030698.1 UniProtKB/TrEMBL
  ENSCAFT00040030900.1 UniProtKB/TrEMBL
  ENSCAFT00040031056.1 UniProtKB/TrEMBL
  ENSCAFT00845021590 ENTREZGENE
  ENSCAFT00845021590.1 UniProtKB/TrEMBL
InterPro WASH_strumpellin UniProtKB/TrEMBL
NCBI Gene WASHC5 ENTREZGENE
PANTHER PTHR15691 UniProtKB/TrEMBL
  WASH COMPLEX SUBUNIT 5 UniProtKB/TrEMBL
Pfam Strumpellin UniProtKB/TrEMBL
UniProt A0A8C0K0L2 ENTREZGENE
  A0A8C0MS07_CANLF UniProtKB/TrEMBL
  A0A8C0MUZ8_CANLF UniProtKB/TrEMBL
  A0A8C0MVQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MXL7_CANLF UniProtKB/TrEMBL
  A0A8C0STV6_CANLF UniProtKB/TrEMBL
  A0A8C0SUL4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0YZS2_CANLF UniProtKB/TrEMBL
  A0A8C0Z055_CANLF UniProtKB/TrEMBL
  A0A8I3NNA7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:48337 ENTREZGENE