AQP6 (aquaporin 6) - Rat Genome Database

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Gene: AQP6 (aquaporin 6) Canis lupus familiaris
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Symbol: AQP6
Name: aquaporin 6
RGD ID: 12371698
Description: ENCODES a protein that exhibits nitrate transmembrane transporter activity (ortholog); INVOLVED IN nitrate transmembrane transport (ortholog); odontogenesis (ortholog); renal water transport (ortholog); PARTICIPATES IN water transport pathway; FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aquaporin-6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,727,732 - 4,731,828 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,727,725 - 4,731,316 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,527,817 - 41,531,698 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,775,594 - 4,779,476 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,776,786 - 4,789,859 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,740,579 - 4,744,460 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,730,402 - 4,734,285 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,922,470 - 41,926,347 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
AQP6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,727,732 - 4,731,828 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,727,725 - 4,731,316 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,527,817 - 41,531,698 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,775,594 - 4,779,476 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,776,786 - 4,789,859 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,740,579 - 4,744,460 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,730,402 - 4,734,285 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,922,470 - 41,926,347 (+)NCBIUU_Cfam_GSD_1.0
AQP6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,972,947 - 49,977,139 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1249,967,194 - 49,977,139 (+)EnsemblGRCh38hg38GRCh38
GRCh371250,366,730 - 50,370,922 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,652,887 - 48,657,189 (+)NCBINCBI36Build 36hg18NCBI36
Build 341248,652,891 - 48,657,189NCBI
Celera1249,162,741 - 49,167,043 (+)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,398,122 - 47,402,424 (+)NCBIHuRef
CHM1_11250,332,778 - 50,337,080 (+)NCBICHM1_1
T2T-CHM13v2.01249,935,958 - 49,940,150 (+)NCBIT2T-CHM13v2.0
Aqp6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,495,891 - 99,503,359 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,499,281 - 99,503,358 (+)EnsemblGRCm39 Ensembl
GRCm381599,598,468 - 99,605,478 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,601,400 - 99,605,477 (+)EnsemblGRCm38mm10GRCm38
MGSCv371599,431,831 - 99,435,908 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,429,434 - 99,433,511 (+)NCBIMGSCv36mm8
Celera15101,756,793 - 101,760,851 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
Aqp6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27130,732,216 - 130,735,149 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,633,579 - 130,735,194 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl7130,633,579 - 130,735,194 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,535,805 - 132,538,735 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07134,761,384 - 134,764,315 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07134,673,911 - 134,676,841 (+)NCBIRnor_WKY
Rnor_6.07141,258,585 - 141,261,518 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,258,584 - 141,261,735 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,763,288 - 115,766,221 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,347,266 - 138,350,199 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17138,423,702 - 138,426,636 (+)NCBI
Celera7127,213,574 - 127,216,507 (+)NCBICelera
Cytogenetic Map7q36NCBI
Aqp6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547567,152 - 571,895 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955547567,152 - 570,880 (+)NCBIChiLan1.0ChiLan1.0
AQP6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11239,672,067 - 39,676,636 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,672,067 - 39,676,636 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01238,739,047 - 38,782,659 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Aqp6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,511,431 - 65,514,075 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365127,650,755 - 7,653,399 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AQP6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,887,966 - 15,890,805 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,888,080 - 15,892,113 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,068,162 - 16,071,435 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AQP6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11146,199,907 - 46,207,010 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037199,914,619 - 199,919,218 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aqp6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,316,668 - 2,319,650 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,314,660 - 2,319,649 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 1
Low 10 5 5 1 8 8 1
Below cutoff 4 4 8 1 6 1 5 2 3 8 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000013289   ⟹   ENSCAFP00000012296
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl274,727,725 - 4,731,316 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000062671   ⟹   ENSCAFP00000047721
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl274,727,725 - 4,731,316 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845032246   ⟹   ENSCAFP00845025206
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl274,776,786 - 4,778,528 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845032273   ⟹   ENSCAFP00845025229
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl274,776,815 - 4,789,859 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845032312   ⟹   ENSCAFP00845025257
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl274,786,100 - 4,789,859 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845032363   ⟹   ENSCAFP00845025296
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl274,786,100 - 4,789,859 (-)Ensembl
RefSeq Acc Id: XM_038438229   ⟹   XP_038294157
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0274,775,594 - 4,779,476 (-)NCBI
RefSeq Acc Id: XM_038512931   ⟹   XP_038368859
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1274,740,579 - 4,744,460 (-)NCBI
RefSeq Acc Id: XM_038577611   ⟹   XP_038433539
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02741,922,470 - 41,926,347 (+)NCBI
RefSeq Acc Id: XM_038640702   ⟹   XP_038496630
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0274,730,402 - 4,734,285 (-)NCBI
RefSeq Acc Id: XM_845359   ⟹   XP_850452
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1274,727,732 - 4,731,828 (-)NCBI
Dog10K_Boxer_Tasha2741,527,817 - 41,531,698 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038294157 (Get FASTA)   NCBI Sequence Viewer  
  XP_038368859 (Get FASTA)   NCBI Sequence Viewer  
  XP_038433539 (Get FASTA)   NCBI Sequence Viewer  
  XP_038496630 (Get FASTA)   NCBI Sequence Viewer  
  XP_850452 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_850452   ⟸   XM_845359
- UniProtKB: F1PAT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000012296   ⟸   ENSCAFT00000013289
RefSeq Acc Id: ENSCAFP00000047721   ⟸   ENSCAFT00000062671
RefSeq Acc Id: XP_038368859   ⟸   XM_038512931
RefSeq Acc Id: XP_038496630   ⟸   XM_038640702
RefSeq Acc Id: XP_038294157   ⟸   XM_038438229
- UniProtKB: F1PAT1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038433539   ⟸   XM_038577611
RefSeq Acc Id: ENSCAFP00845025229   ⟸   ENSCAFT00845032273
RefSeq Acc Id: ENSCAFP00845025206   ⟸   ENSCAFT00845032246
RefSeq Acc Id: ENSCAFP00845025296   ⟸   ENSCAFT00845032363
RefSeq Acc Id: ENSCAFP00845025257   ⟸   ENSCAFT00845032312


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008366 Ensembl
  ENSCAFG00845018235 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00845025206.1 UniProtKB/TrEMBL
  ENSCAFP00845025229.1 UniProtKB/TrEMBL
  ENSCAFP00845025257.1 UniProtKB/TrEMBL
  ENSCAFP00845025296.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845032246.1 UniProtKB/TrEMBL
  ENSCAFT00845032273.1 UniProtKB/TrEMBL
  ENSCAFT00845032312.1 UniProtKB/TrEMBL
  ENSCAFT00845032363.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1080.10 UniProtKB/TrEMBL
InterPro Aquaporin-like UniProtKB/TrEMBL
  Aquaporin_5 UniProtKB/TrEMBL
  Aquaporin_6 UniProtKB/TrEMBL
  Aquaporin_transptr UniProtKB/TrEMBL
  MIP UniProtKB/TrEMBL
  MIP_CS UniProtKB/TrEMBL
NCBI Gene AQP6 ENTREZGENE
PANTHER PTHR19139 UniProtKB/TrEMBL
  PTHR19139:SF113 UniProtKB/TrEMBL
  PTHR19139:SF38 UniProtKB/TrEMBL
Pfam MIP UniProtKB/TrEMBL
PRINTS AQUAPORIN5 UniProtKB/TrEMBL
  AQUAPORIN6 UniProtKB/TrEMBL
  MINTRINSICP UniProtKB/TrEMBL
PROSITE MIP UniProtKB/TrEMBL
Superfamily-SCOP SSF81338 UniProtKB/TrEMBL
UniProt A0A8I3NZR7_CANLF UniProtKB/TrEMBL
  A0A8I3P5Q9_CANLF UniProtKB/TrEMBL
  A0A8I3PD19_CANLF UniProtKB/TrEMBL
  A0A8I3S0D4_CANLF UniProtKB/TrEMBL
  F1PAT1 ENTREZGENE
VGNC ID VGNC:38019 ENTREZGENE