ARPC2 (actin related protein 2/3 complex subunit 2) - Rat Genome Database

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Gene: ARPC2 (actin related protein 2/3 complex subunit 2) Canis lupus familiaris
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Symbol: ARPC2
Name: actin related protein 2/3 complex subunit 2
RGD ID: 12362532
Description: ENCODES a protein that exhibits actin filament binding (ortholog); AP-1 adaptor complex binding (ortholog); Arp2/3 complex binding (ortholog); INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); cellular response to nerve growth factor stimulus (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; platelet-derived growth factor signaling pathway; Rab family mediated signaling pathway; ASSOCIATED WITH alacrima, achalasia, and impaired intellectual development syndrome (ortholog); cerebrotendinous xanthomatosis (ortholog); colorectal adenocarcinoma (ortholog); FOUND IN actin filament branch point (ortholog); apical dendrite (ortholog); axon terminus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: actin-related protein 2/3 complex subunit 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13724,914,389 - 24,935,998 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3724,914,642 - 24,935,824 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3725,726,741 - 25,756,145 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03724,922,615 - 24,952,042 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3724,922,535 - 24,952,248 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13724,827,991 - 24,857,388 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03724,762,177 - 24,791,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03724,781,773 - 24,811,231 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
ARPC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13724,914,389 - 24,935,998 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3724,914,642 - 24,935,824 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3725,726,741 - 25,756,145 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03724,922,615 - 24,952,042 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3724,922,535 - 24,952,248 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13724,827,991 - 24,857,388 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03724,762,177 - 24,791,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03724,781,773 - 24,811,231 (+)NCBIUU_Cfam_GSD_1.0
ARPC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,217,189 - 218,254,348 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2218,217,141 - 218,254,356 (+)EnsemblGRCh38hg38GRCh38
GRCh372219,081,912 - 219,119,071 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,790,119 - 218,827,316 (+)NCBINCBI36Build 36hg18NCBI36
Build 342218,907,379 - 218,944,576NCBI
Celera2212,848,449 - 212,885,654 (+)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2210,934,975 - 210,972,151 (+)NCBIHuRef
CHM1_12219,088,288 - 219,125,558 (+)NCBICHM1_1
T2T-CHM13v2.02218,702,891 - 218,740,055 (+)NCBIT2T-CHM13v2.0
Arpc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,275,656 - 74,307,368 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,275,243 - 74,307,368 (+)EnsemblGRCm39 Ensembl
GRCm38174,236,490 - 74,268,209 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,236,084 - 74,268,209 (+)EnsemblGRCm38mm10GRCm38
MGSCv37174,283,124 - 74,314,787 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36174,169,706 - 74,201,416 (+)NCBIMGSCv36mm8
Celera174,797,918 - 74,829,569 (+)NCBICelera
Cytogenetic Map1C3NCBI
cM Map138.49NCBI
Arpc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2975,820,782 - 75,851,471 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl975,820,770 - 75,851,471 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx984,271,669 - 84,296,962 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0989,400,588 - 89,425,881 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0987,786,805 - 87,812,098 (+)NCBIRnor_WKY
Rnor_6.0981,518,163 - 81,548,871 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,518,176 - 81,548,871 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,285,084 - 81,315,844 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,563,617 - 73,594,263 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1973,710,470 - 73,741,240 (+)NCBI
Celera973,397,334 - 73,427,983 (+)NCBICelera
Cytogenetic Map9q33NCBI
Arpc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545315,116,093 - 15,146,041 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545315,117,978 - 15,145,895 (-)NCBIChiLan1.0ChiLan1.0
ARPC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B224,076,356 - 224,111,643 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B224,076,356 - 224,111,643 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B105,478,035 - 105,513,665 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Arpc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303174,415,593 - 174,443,979 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936569758,199 - 786,760 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936569758,358 - 786,995 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARPC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15120,297,025 - 120,328,542 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115120,297,122 - 120,328,795 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215133,376,755 - 133,421,942 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARPC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110104,098,275 - 104,144,043 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10104,098,402 - 104,135,791 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604095,260,455 - 95,302,739 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arpc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248236,774,855 - 6,804,219 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ARPC2
186 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000023209   ⟹   ENSCAFP00000021552
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3724,914,642 - 24,935,824 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845046777   ⟹   ENSCAFP00845036694
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3724,922,535 - 24,952,248 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845046863   ⟹   ENSCAFP00845036754
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3724,922,649 - 24,952,243 (+)Ensembl
RefSeq Acc Id: XM_038447922   ⟹   XP_038303850
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03724,922,615 - 24,952,042 (+)NCBI
RefSeq Acc Id: XM_038463633   ⟹   XP_038319561
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3725,726,741 - 25,756,145 (+)NCBI
RefSeq Acc Id: XM_038521917   ⟹   XP_038377845
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13724,827,991 - 24,857,388 (+)NCBI
RefSeq Acc Id: XM_038585714   ⟹   XP_038441642
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03724,781,773 - 24,811,231 (+)NCBI
RefSeq Acc Id: XM_038650094   ⟹   XP_038506022
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03724,762,177 - 24,791,643 (+)NCBI
Reference Sequences
RefSeq Acc Id: ENSCAFP00000021552   ⟸   ENSCAFT00000023209
RefSeq Acc Id: XP_038377845   ⟸   XM_038521917
RefSeq Acc Id: XP_038506022   ⟸   XM_038650094
RefSeq Acc Id: XP_038303850   ⟸   XM_038447922
- UniProtKB: A0A8C0LSC2 (UniProtKB/TrEMBL),   A0A8C0THE8 (UniProtKB/TrEMBL),   A0A8I3PPW3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319561   ⟸   XM_038463633
- UniProtKB: A0A8C0LSC2 (UniProtKB/TrEMBL),   A0A8C0THE8 (UniProtKB/TrEMBL),   A0A8I3PPW3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441642   ⟸   XM_038585714
RefSeq Acc Id: ENSCAFP00845036754   ⟸   ENSCAFT00845046863
RefSeq Acc Id: ENSCAFP00845036694   ⟸   ENSCAFT00845046777


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014618 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040023014 UniProtKB/TrEMBL
  ENSCAFG00845026524 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000021552.5 UniProtKB/TrEMBL
  ENSCAFP00040037307 UniProtKB/TrEMBL
  ENSCAFP00845036694.1 UniProtKB/TrEMBL
  ENSCAFP00845036754 ENTREZGENE
  ENSCAFP00845036754.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000023209.5 UniProtKB/TrEMBL
  ENSCAFT00040042771 UniProtKB/TrEMBL
  ENSCAFT00845046777.1 UniProtKB/TrEMBL
  ENSCAFT00845046863 ENTREZGENE
  ENSCAFT00845046863.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1460.20 UniProtKB/TrEMBL
InterPro ARPC2 UniProtKB/TrEMBL
  ARPC2/4 UniProtKB/TrEMBL
NCBI Gene ARPC2 ENTREZGENE
PANTHER PTHR12058 UniProtKB/TrEMBL
Pfam P34-Arc UniProtKB/TrEMBL
Superfamily-SCOP SSF69645 UniProtKB/TrEMBL
UniProt A0A8C0LSC2 ENTREZGENE
  A0A8C0THE8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PPQ5_CANLF UniProtKB/TrEMBL
  A0A8I3PPW3 ENTREZGENE, UniProtKB/TrEMBL