OR6C75C (olfactory receptor family 6 subfamily C member 75C) - Rat Genome Database

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Gene: OR6C75C (olfactory receptor family 6 subfamily C member 75C) Canis lupus familiaris
Analyze
Symbol: OR6C75C
Name: olfactory receptor family 6 subfamily C member 75C
RGD ID: 12361632
Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC100686973; olfactory receptor 6C75-like
RGD Orthologs
Human
Mouse
Rat
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12941,768,470 - 41,769,487 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2941,768,470 - 41,769,408 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02941,963,114 - 41,964,052 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2941,963,114 - 41,964,052 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12942,001,323 - 42,002,261 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02941,971,533 - 41,972,471 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02942,436,975 - 42,437,913 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
OR6C75C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12941,768,470 - 41,769,487 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2941,768,470 - 41,769,408 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02941,963,114 - 41,964,052 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2941,963,114 - 41,964,052 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12942,001,323 - 42,002,261 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02941,971,533 - 41,972,471 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02942,436,975 - 42,437,913 (-)NCBIUU_Cfam_GSD_1.0
OR6C75
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381255,362,975 - 55,369,279 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1255,362,975 - 55,369,279 (+)EnsemblGRCh38hg38GRCh38
GRCh371255,756,759 - 55,763,063 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,045,162 - 54,046,100 (+)NCBINCBI36Build 36hg18NCBI36
Build 341254,045,161 - 54,046,100NCBI
Celera1255,410,961 - 55,411,899 (+)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1252,797,687 - 52,798,625 (+)NCBIHuRef
CHM1_11255,725,708 - 55,726,646 (+)NCBICHM1_1
T2T-CHM13v2.01255,329,536 - 55,335,853 (+)NCBIT2T-CHM13v2.0
Or6c75
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910129,336,755 - 129,337,723 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10129,334,361 - 129,339,211 (+)EnsemblGRCm39 Ensembl
GRCm3810129,500,886 - 129,501,854 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10129,498,492 - 129,503,342 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710128,937,942 - 128,938,910 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610128,903,835 - 128,904,803 (+)NCBIMGSCv36mm8
Celera10131,886,844 - 131,887,812 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.35NCBI
Or6c7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr876,015,857 - 6,016,795 (+)NCBIGRCr8
mRatBN7.275,365,024 - 5,365,962 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl75,362,978 - 5,367,644 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx78,259,343 - 8,260,281 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0710,135,001 - 10,135,939 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.077,970,269 - 7,971,207 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.077,068,703 - 7,069,641 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl77,068,703 - 7,069,641 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.077,165,984 - 7,166,922 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.476,761,553 - 6,762,491 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.176,761,552 - 6,762,491 (+)NCBI
Celera73,611,622 - 3,612,560 (+)NCBICelera
Cytogenetic Map7q11NCBI
LOC100155964
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1520,519,071 - 20,523,965 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2521,499,141 - 21,500,138 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103238463
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11151,360,056 - 51,361,537 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037194,654,780 - 194,655,884 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in OR6C75C
85 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system reproductive system
High
Medium
Low 1
Below cutoff 1 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000015089   ⟹   ENSCAFP00000013962
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2941,768,470 - 41,769,408 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845031100   ⟹   ENSCAFP00845024357
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2941,963,114 - 41,964,052 (-)Ensembl
RefSeq Acc Id: NM_001389064   ⟹   NP_001375993
RefSeq Status: INFERRED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02941,963,114 - 41,964,052 (-)NCBI
UMICH_Zoey_3.12942,001,323 - 42,002,261 (-)NCBI
UNSW_CanFamBas_1.02941,971,533 - 41,972,471 (-)NCBI
UU_Cfam_GSD_1.02942,436,975 - 42,437,913 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001375993 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00030035033.1
  ENSCAFP00040037448.1
  ENSCAFP00845024357
  ENSCAFP00845024357.1
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000013962   ⟸   ENSCAFT00000015089
RefSeq Acc Id: NP_001375993   ⟸   NM_001389064
- UniProtKB: A0A8I3S2P6 (UniProtKB/TrEMBL),   A0A8C0P0A1 (UniProtKB/TrEMBL),   A0A8C0THR8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845024357   ⟸   ENSCAFT00845031100
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009495 Ensembl
  ENSCAFG00030021890 UniProtKB/TrEMBL
  ENSCAFG00040023107 UniProtKB/TrEMBL
  ENSCAFG00845017568 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030040148.1 UniProtKB/TrEMBL
  ENSCAFT00040042927.1 UniProtKB/TrEMBL
  ENSCAFT00845031100 ENTREZGENE
  ENSCAFT00845031100.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfact_rcpt_6C-like UniProtKB/TrEMBL
NCBI Gene LOC100686973 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR FAMILY 6 SUBFAMILY C MEMBER 75C UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0P0A1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0THR8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S2P6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:97078 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-18 OR6C75C  olfactory receptor family 6 subfamily C member 75C  LOC100686973  olfactory receptor 6C75-like  Symbol and/or name change 5135510 APPROVED