TRIM25 (tripartite motif containing 25) - Rat Genome Database

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Gene: TRIM25 (tripartite motif containing 25) Canis lupus familiaris
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Symbol: TRIM25
Name: tripartite motif containing 25
RGD ID: 12361388
Description: ENCODES a protein that exhibits metal ion binding (inferred); RIG-I binding (inferred); transcription coactivator activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); positive regulation of DNA-binding transcription factor activity (ortholog); regulation of viral entry into host cell (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: E3 ubiquitin/ISG15 ligase TRIM25
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1931,703,628 - 31,725,674 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl931,707,034 - 31,725,762 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha930,943,465 - 30,965,495 (-)NCBI
ROS_Cfam_1.0932,511,355 - 32,533,408 (-)NCBI
UMICH_Zoey_3.1931,296,490 - 31,318,526 (-)NCBI
UNSW_CanFamBas_1.0931,580,728 - 31,602,758 (-)NCBI
UU_Cfam_GSD_1.0931,664,093 - 31,686,131 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
TRIM25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1931,703,628 - 31,725,674 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl931,707,034 - 31,725,762 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha930,943,465 - 30,965,495 (-)NCBI
ROS_Cfam_1.0932,511,355 - 32,533,408 (-)NCBI
UMICH_Zoey_3.1931,296,490 - 31,318,526 (-)NCBI
UNSW_CanFamBas_1.0931,580,728 - 31,602,758 (-)NCBI
UU_Cfam_GSD_1.0931,664,093 - 31,686,131 (-)NCBI
TRIM25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1756,836,387 - 56,914,080 (-)EnsemblGRCh38hg38GRCh38
GRCh381756,887,909 - 56,914,049 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371754,965,270 - 54,991,410 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361752,320,269 - 52,346,408 (-)NCBINCBI36hg18NCBI36
Build 341752,323,634 - 52,346,408NCBI
Celera1751,426,842 - 51,452,985 (-)NCBI
Cytogenetic Map17q22NCBI
HuRef1750,325,845 - 50,351,990 (-)NCBIHuRef
CHM1_11755,030,515 - 55,056,657 (-)NCBICHM1_1
Trim25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391188,890,194 - 88,911,119 (+)NCBIGRCm39mm39
GRCm39 Ensembl1188,890,202 - 88,911,119 (+)Ensembl
GRCm381188,999,403 - 89,020,294 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1188,999,376 - 89,020,293 (+)EnsemblGRCm38mm10GRCm38
MGSCv371188,860,717 - 88,881,607 (+)NCBIGRCm37mm9NCBIm37
MGSCv361188,815,570 - 88,836,383 (+)NCBImm8
Celera1198,615,674 - 98,636,481 (+)NCBICelera
Cytogenetic Map11CNCBI
Trim25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21073,812,818 - 73,831,271 (+)NCBI
Rnor_6.0 Ensembl1076,343,847 - 76,362,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01076,343,847 - 76,362,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01073,750,003 - 73,769,423 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41077,459,844 - 77,488,383 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1072,717,934 - 72,735,695 (+)NCBICelera
Cytogenetic Map10q26NCBI
Trim25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554515,918,287 - 5,934,258 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554515,918,287 - 5,934,252 (+)NCBIChiLan1.0ChiLan1.0
TRIM25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11755,826,458 - 55,852,422 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1755,826,458 - 55,852,422 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01750,965,592 - 50,991,630 (-)NCBIMhudiblu_PPA_v0panPan3
Trim25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560231,081,655 - 31,095,879 (-)NCBI
SpeTri2.0NW_0049364905,979,320 - 5,997,632 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1233,184,044 - 33,212,398 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11233,184,039 - 33,212,440 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21234,134,354 - 34,153,408 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM25
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11636,496,829 - 36,522,427 (+)NCBI
ChlSab1.1 Ensembl1636,496,772 - 36,524,148 (+)Ensembl
Vero_WHO_p1.0NW_0236660777,316,204 - 7,343,303 (+)NCBI
Trim25
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479511,967,908 - 11,986,707 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 1 22 6 6 6 6 6 10 6
Low 4 6 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000027553   ⟹   ENSCAFP00000025624
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl931,707,034 - 31,725,762 (-)Ensembl
RefSeq Acc Id: XM_038486026   ⟹   XP_038341954
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1931,296,490 - 31,318,526 (-)NCBI
RefSeq Acc Id: XM_038547807   ⟹   XP_038403735
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0931,664,093 - 31,686,131 (-)NCBI
RefSeq Acc Id: XM_038611789   ⟹   XP_038467717
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0931,580,728 - 31,602,758 (-)NCBI
RefSeq Acc Id: XM_038677013   ⟹   XP_038532941
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0932,511,355 - 32,533,408 (-)NCBI
RefSeq Acc Id: XM_548223   ⟹   XP_548223
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1931,703,628 - 31,725,674 (-)NCBI
Dog10K_Boxer_Tasha930,943,465 - 30,965,495 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038341954 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403735 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467717 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532941 (Get FASTA)   NCBI Sequence Viewer  
  XP_548223 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_548223   ⟸   XM_548223
- UniProtKB: F1PTE2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000025624   ⟸   ENSCAFT00000027553
RefSeq Acc Id: XP_038341954   ⟸   XM_038486026
RefSeq Acc Id: XP_038467717   ⟸   XM_038611789
RefSeq Acc Id: XP_038532941   ⟸   XM_038677013
RefSeq Acc Id: XP_038403735   ⟸   XM_038547807
Protein Domains
B30.2/SPRY   RING-type

Promoters
RGD ID:13684609
Promoter ID:EPDNEW_C2678
Type:multiple initiation site
Name:TRIM25_1
Description:tripartite motif containing 25
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1931,725,638 - 31,725,698EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017390 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000025624 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027553 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin UniProtKB/TrEMBL
  ConA-like_dom UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  TRIM25_SPRY_PRY UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report cfa:491103 UniProtKB/TrEMBL
NCBI Gene TRIM25 ENTREZGENE
Pfam PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART PRY UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
UniProt F1PTE2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47810 ENTREZGENE