ECE1 (endothelin converting enzyme 1) - Rat Genome Database

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Gene: ECE1 (endothelin converting enzyme 1) Canis lupus familiaris
Analyze
Symbol: ECE1
Name: endothelin converting enzyme 1
RGD ID: 12361271
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN apoptotic process (ortholog); blood vessel diameter maintenance (ortholog); bradykinin catabolic process (ortholog); PARTICIPATES IN endothelin signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Alzheimer's disease (ortholog); autonomic nervous system disease (ortholog); FOUND IN cytoplasmic vesicle (ortholog); early endosome (ortholog); endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: endothelin-converting enzyme 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1277,732,645 - 77,793,950 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl277,678,686 - 77,792,114 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha274,191,949 - 74,307,168 (+)NCBI
ROS_Cfam_1.0278,248,131 - 78,362,573 (+)NCBI
UMICH_Zoey_3.1275,065,942 - 75,181,163 (+)NCBI
UNSW_CanFamBas_1.0276,130,913 - 76,192,255 (+)NCBI
UU_Cfam_GSD_1.0277,133,728 - 77,195,129 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
ECE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1277,732,645 - 77,793,950 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl277,678,686 - 77,792,114 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha274,191,949 - 74,307,168 (+)NCBI
ROS_Cfam_1.0278,248,131 - 78,362,573 (+)NCBI
UMICH_Zoey_3.1275,065,942 - 75,181,163 (+)NCBI
UNSW_CanFamBas_1.0276,130,913 - 76,192,255 (+)NCBI
UU_Cfam_GSD_1.0277,133,728 - 77,195,129 (+)NCBI
ECE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl121,217,247 - 21,345,572 (-)EnsemblGRCh38hg38GRCh38
GRCh38121,217,250 - 21,345,504 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37121,543,743 - 21,671,997 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36121,418,939 - 21,489,494 (-)NCBINCBI36hg18NCBI36
Build 34121,291,657 - 21,362,213NCBI
Celera119,868,639 - 19,996,910 (-)NCBI
Cytogenetic Map1p36.12NCBI
HuRef119,789,436 - 19,917,657 (-)NCBIHuRef
CHM1_1121,655,386 - 21,783,707 (-)NCBICHM1_1
Ece1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394137,589,548 - 137,692,540 (+)NCBIGRCm39mm39
GRCm39 Ensembl4137,589,548 - 137,692,540 (+)Ensembl
GRCm384137,862,237 - 137,965,229 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4137,862,237 - 137,965,229 (+)EnsemblGRCm38mm10GRCm38
MGSCv374137,418,152 - 137,521,144 (+)NCBIGRCm37mm9NCBIm37
MGSCv364137,134,373 - 137,237,305 (+)NCBImm8
Celera4136,126,032 - 136,196,612 (+)NCBICelera
Cytogenetic Map4D3NCBI
Ece1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25150,077,679 - 150,179,375 (+)NCBI
Rnor_6.0 Ensembl5156,215,417 - 156,318,671 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05156,215,469 - 156,318,652 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05159,968,604 - 160,075,347 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45156,635,656 - 156,735,783 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15156,645,659 - 156,747,472 (+)NCBI
Celera5148,472,086 - 148,571,980 (+)NCBICelera
Cytogenetic Map5q36NCBI
Ece1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554521,651,316 - 1,751,489 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554521,653,783 - 1,704,619 (-)NCBIChiLan1.0ChiLan1.0
ECE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1121,206,199 - 21,278,909 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl121,206,199 - 21,278,909 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0120,166,019 - 20,290,803 (-)NCBIMhudiblu_PPA_v0panPan3
Ece1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505841,209,358 - 41,258,192 (-)NCBI
SpeTri2.0NW_0049364747,034,134 - 7,083,005 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ECE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl679,408,328 - 79,466,106 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1679,408,322 - 79,465,827 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2673,659,673 - 73,781,925 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ECE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120111,212,567 - 111,342,755 (+)NCBI
ChlSab1.1 Ensembl20111,212,594 - 111,342,821 (+)Ensembl
Vero_WHO_p1.0NW_0236660334,933,846 - 5,063,084 (-)NCBI
Ece1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247646,222,301 - 6,318,423 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 10 6
Low 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005617844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022413659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038463449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038470829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038470830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038531708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038595944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038595945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038595946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038660024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038660025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ195100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000023718   ⟹   ENSCAFP00000022019
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl277,678,686 - 77,792,114 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000066706   ⟹   ENSCAFP00000048128
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl277,732,434 - 77,792,114 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000085289   ⟹   ENSCAFP00000058384
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl277,732,434 - 77,792,114 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000089114   ⟹   ENSCAFP00000056121
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl277,733,419 - 77,792,114 (+)Ensembl
RefSeq Acc Id: XM_005617844   ⟹   XP_005617901
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1277,733,646 - 77,793,950 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022413659   ⟹   XP_022269367
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1277,732,645 - 77,793,950 (+)NCBI
Dog10K_Boxer_Tasha274,245,777 - 74,307,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038463449   ⟹   XP_038319377
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha274,191,949 - 74,305,309 (+)NCBI
RefSeq Acc Id: XM_038470829   ⟹   XP_038326757
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1275,120,738 - 75,181,163 (+)NCBI
RefSeq Acc Id: XM_038470830   ⟹   XP_038326758
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1275,065,942 - 75,179,297 (+)NCBI
RefSeq Acc Id: XM_038531708   ⟹   XP_038387636
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0277,133,728 - 77,195,129 (+)NCBI
RefSeq Acc Id: XM_038595944   ⟹   XP_038451872
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0276,130,913 - 76,192,255 (+)NCBI
RefSeq Acc Id: XM_038595945   ⟹   XP_038451873
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0276,131,659 - 76,190,387 (+)NCBI
RefSeq Acc Id: XM_038595946   ⟹   XP_038451874
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0276,131,950 - 76,192,255 (+)NCBI
RefSeq Acc Id: XM_038660024   ⟹   XP_038515952
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0278,301,074 - 78,362,573 (+)NCBI
RefSeq Acc Id: XM_038660025   ⟹   XP_038515953
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0278,248,131 - 78,360,705 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005617901   ⟸   XM_005617844
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_022269367   ⟸   XM_022413659
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000048128   ⟸   ENSCAFT00000066706
RefSeq Acc Id: ENSCAFP00000022019   ⟸   ENSCAFT00000023718
RefSeq Acc Id: ENSCAFP00000056121   ⟸   ENSCAFT00000089114
RefSeq Acc Id: ENSCAFP00000058384   ⟸   ENSCAFT00000085289
RefSeq Acc Id: XP_038326758   ⟸   XM_038470830
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038326757   ⟸   XM_038470829
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038451872   ⟸   XM_038595944
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038451873   ⟸   XM_038595945
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038451874   ⟸   XM_038595946
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038515953   ⟸   XM_038660025
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038515952   ⟸   XM_038660024
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038319377   ⟸   XM_038463449
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038387636   ⟸   XM_038531708
- Peptide Label: isoform X1
Protein Domains
Peptidase_M13   Peptidase_M13_N


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014920 Ensembl, ENTREZGENE
Ensembl Protein ENSCAFP00000048128 ENTREZGENE
NCBI Gene ECE1 ENTREZGENE
VGNC ID VGNC:40181 ENTREZGENE