IGSF8 (immunoglobulin superfamily member 8) - Rat Genome Database

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Gene: IGSF8 (immunoglobulin superfamily member 8) Canis lupus familiaris
Analyze
Symbol: IGSF8
Name: immunoglobulin superfamily member 8
RGD ID: 12360808
Description: INVOLVED IN modulation of chemical synaptic transmission (ortholog); regulation of cell motility (ortholog); ASSOCIATED WITH autoimmune interstitial lung, joint, and kidney disease (ortholog); EAST syndrome (ortholog); familial hemiplegic migraine (ortholog); FOUND IN axon (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13822,093,463 - 22,100,009 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3822,062,591 - 22,100,020 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3822,166,225 - 22,173,180 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03822,209,636 - 22,216,585 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3822,180,129 - 22,216,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13822,114,099 - 22,121,044 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03822,510,596 - 22,517,560 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,920,492 - 22,927,445 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
IGSF8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13822,093,463 - 22,100,009 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3822,062,591 - 22,100,020 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3822,166,225 - 22,173,180 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03822,209,636 - 22,216,585 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3822,180,129 - 22,216,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13822,114,099 - 22,121,044 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03822,510,596 - 22,517,560 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,920,492 - 22,927,445 (+)NCBIUU_Cfam_GSD_1.0
IGSF8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,091,339 - 160,099,468 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1160,091,340 - 160,098,943 (-)EnsemblGRCh38hg38GRCh38
GRCh371160,061,129 - 160,068,618 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361158,327,754 - 158,335,032 (-)NCBINCBI36Build 36hg18NCBI36
Build 341156,874,203 - 156,881,481NCBI
Celera1133,129,914 - 133,137,192 (-)NCBICelera
Cytogenetic Map1q23.2NCBI
HuRef1131,418,244 - 131,425,733 (-)NCBIHuRef
CHM1_11161,456,514 - 161,464,003 (-)NCBICHM1_1
T2T-CHM13v2.01159,228,416 - 159,236,545 (-)NCBIT2T-CHM13v2.0
Igsf8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391172,139,934 - 172,147,410 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1172,089,208 - 172,147,408 (+)EnsemblGRCm39 Ensembl
GRCm381172,312,367 - 172,319,843 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,261,641 - 172,319,841 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,242,538 - 174,249,968 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,149,082 - 174,156,512 (+)NCBIMGSCv36mm8
Celera1175,165,962 - 175,173,390 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.59NCBI
Igsf8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81387,282,015 - 87,314,018 (+)NCBIGRCr8
mRatBN7.21384,770,348 - 84,781,534 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1384,770,279 - 84,778,576 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1387,273,715 - 87,281,889 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01388,673,987 - 88,682,165 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01385,858,305 - 85,866,459 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01390,692,590 - 90,703,262 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,692,666 - 90,700,789 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,193,429 - 95,221,983 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,301,142 - 88,309,250 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11388,490,025 - 88,498,134 (+)NCBI
Celera1384,380,746 - 84,388,864 (+)NCBICelera
Cytogenetic Map13q24NCBI
Igsf8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546811,877,369 - 11,883,962 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546811,877,369 - 11,883,962 (-)NCBIChiLan1.0ChiLan1.0
IGSF8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2189,752,742 - 89,760,850 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1189,492,753 - 89,500,863 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01135,445,180 - 135,452,684 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11139,366,220 - 139,370,711 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1139,366,228 - 139,374,732 (-)Ensemblpanpan1.1panPan2
Igsf8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050586,218,735 - 6,225,650 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936740528,821 - 535,776 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936740528,826 - 535,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGSF8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl490,393,624 - 90,401,369 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1490,393,614 - 90,401,380 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2498,335,001 - 98,342,777 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IGSF8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1203,845,767 - 3,853,077 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl203,848,946 - 3,852,609 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660382,903,087 - 2,910,432 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igsf8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247941,155,270 - 1,164,960 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247941,155,452 - 1,162,191 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IGSF8
133 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 22 6 6 6 6 12 8 10 6
Low 5 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003640213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005640900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038464144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038464145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038464146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000048290   ⟹   ENSCAFP00000037560
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3822,093,390 - 22,100,020 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000050050   ⟹   ENSCAFP00000040914
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3822,093,462 - 22,099,937 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000079402   ⟹   ENSCAFP00000061596
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3822,062,591 - 22,099,937 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845054787   ⟹   ENSCAFP00845043096
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3822,180,129 - 22,216,581 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845054799   ⟹   ENSCAFP00845043107
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3822,209,682 - 22,216,581 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845054818   ⟹   ENSCAFP00845043122
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3822,212,576 - 22,216,581 (+)Ensembl
RefSeq Acc Id: XM_038448700   ⟹   XP_038304628
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03822,211,246 - 22,216,585 (+)NCBI
RefSeq Acc Id: XM_038448701   ⟹   XP_038304629
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03822,211,247 - 22,216,585 (+)NCBI
RefSeq Acc Id: XM_038448702   ⟹   XP_038304630
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03822,209,636 - 22,216,585 (+)NCBI
RefSeq Acc Id: XM_038464144   ⟹   XP_038320072
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3822,167,843 - 22,173,180 (+)NCBI
RefSeq Acc Id: XM_038464145   ⟹   XP_038320073
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3822,167,843 - 22,173,180 (+)NCBI
RefSeq Acc Id: XM_038464146   ⟹   XP_038320074
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3822,166,225 - 22,173,180 (+)NCBI
RefSeq Acc Id: XM_038522584   ⟹   XP_038378512
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13822,114,099 - 22,121,044 (+)NCBI
RefSeq Acc Id: XM_038586370   ⟹   XP_038442298
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03822,922,107 - 22,927,445 (+)NCBI
RefSeq Acc Id: XM_038586371   ⟹   XP_038442299
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03822,922,107 - 22,927,445 (+)NCBI
RefSeq Acc Id: XM_038586372   ⟹   XP_038442300
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03822,920,492 - 22,927,445 (+)NCBI
RefSeq Acc Id: XM_038650789   ⟹   XP_038506717
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03822,512,213 - 22,517,560 (+)NCBI
RefSeq Acc Id: XM_038650790   ⟹   XP_038506718
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03822,512,213 - 22,517,560 (+)NCBI
RefSeq Acc Id: XM_038650791   ⟹   XP_038506719
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03822,510,596 - 22,517,560 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000040914   ⟸   ENSCAFT00000050050
RefSeq Acc Id: ENSCAFP00000061596   ⟸   ENSCAFT00000079402
RefSeq Acc Id: ENSCAFP00000037560   ⟸   ENSCAFT00000048290
RefSeq Acc Id: XP_038378512   ⟸   XM_038522584
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038506719   ⟸   XM_038650791
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038506717   ⟸   XM_038650789
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038506718   ⟸   XM_038650790
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038304630   ⟸   XM_038448702
- Peptide Label: isoform X3
- UniProtKB: A0A8I3QBY6 (UniProtKB/TrEMBL),   A0A8C0T2M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038304628   ⟸   XM_038448700
- Peptide Label: isoform X1
- UniProtKB: A0A8I3QVD7 (UniProtKB/TrEMBL),   A0A8C0T2M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038304629   ⟸   XM_038448701
- Peptide Label: isoform X2
- UniProtKB: A0A8C0T2M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038320074   ⟸   XM_038464146
- Peptide Label: isoform X3
- UniProtKB: A0A8C0L8J8 (UniProtKB/TrEMBL),   A0A8C0T2M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038320072   ⟸   XM_038464144
- Peptide Label: isoform X1
- UniProtKB: A0A8P0SUY4 (UniProtKB/TrEMBL),   A0A8C0T2M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038320073   ⟸   XM_038464145
- Peptide Label: isoform X2
- UniProtKB: A0A8C0T2M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442300   ⟸   XM_038586372
- Peptide Label: isoform X3
- UniProtKB: A0A8C0L8J8 (UniProtKB/TrEMBL),   A0A8C0T2M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442298   ⟸   XM_038586370
- Peptide Label: isoform X1
- UniProtKB: A0A8C0T2M8 (UniProtKB/TrEMBL),   A0A8P0SUY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442299   ⟸   XM_038586371
- Peptide Label: isoform X2
- UniProtKB: A0A8C0T2M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845043107   ⟸   ENSCAFT00845054799
RefSeq Acc Id: ENSCAFP00845043096   ⟸   ENSCAFT00845054787
RefSeq Acc Id: ENSCAFP00845043122   ⟸   ENSCAFT00845054818
Protein Domains
Ig-like

Promoters
RGD ID:13689228
Promoter ID:EPDNEW_C7297
Type:multiple initiation site
Name:IGSF8_1
Description:immunoglobulin superfamily member 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13822,093,478 - 22,093,538EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000028933 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040017927 UniProtKB/TrEMBL
  ENSCAFG00845030820 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000048290.3 UniProtKB/TrEMBL
  ENSCAFT00000050050.4 UniProtKB/TrEMBL
  ENSCAFT00000079402.2 UniProtKB/TrEMBL
  ENSCAFT00040033081.1 UniProtKB/TrEMBL
  ENSCAFT00845054787.1 UniProtKB/TrEMBL
  ENSCAFT00845054799 ENTREZGENE
  ENSCAFT00845054799.1 UniProtKB/TrEMBL
  ENSCAFT00845054818 ENTREZGENE
  ENSCAFT00845054818.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
NCBI Gene IGSF8 ENTREZGENE
PANTHER IMMUNOGLOBULIN SUPERFAMILY MEMBER 8 UniProtKB/TrEMBL
  V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8C0L8J8 ENTREZGENE
  A0A8C0T2M8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q7X2_CANLF UniProtKB/TrEMBL
  A0A8I3QBY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QVD7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NPG5_CANLF UniProtKB/TrEMBL
  A0A8P0PAG0_CANLF UniProtKB/TrEMBL
  A0A8P0SUY4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:41918 ENTREZGENE