OR6K2 (olfactory receptor family 6 subfamily K member 2) - Rat Genome Database

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Gene: OR6K2 (olfactory receptor family 6 subfamily K member 2) Canis lupus familiaris
Analyze
Symbol: OR6K2
Name: olfactory receptor family 6 subfamily K member 2
RGD ID: 12353756
Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC610561; olfactory receptor 6K2; olfactory receptor 6K2-like; olfactory receptor OR0415
RGD Orthologs
Human
Mouse
Rat
Bonobo
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13823,042,900 - 23,045,240 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3823,043,721 - 23,044,686 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3823,065,822 - 23,066,787 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03823,175,283 - 23,176,248 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13822,938,358 - 22,939,322 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03823,473,085 - 23,474,050 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03823,904,351 - 23,905,316 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
OR6K2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13823,042,900 - 23,045,240 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3823,043,721 - 23,044,686 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3823,065,822 - 23,066,787 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03823,175,283 - 23,176,248 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13822,938,358 - 22,939,322 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03823,473,085 - 23,474,050 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03823,904,351 - 23,905,316 (+)NCBIUU_Cfam_GSD_1.0
OR6K2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381158,699,678 - 158,700,652 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1158,699,678 - 158,700,652 (-)EnsemblGRCh38hg38GRCh38
GRCh371158,669,468 - 158,670,442 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,936,092 - 156,937,066 (-)NCBINCBI36Build 36hg18NCBI36
Build 341155,482,540 - 155,483,515NCBI
Celera1131,740,163 - 131,741,137 (-)NCBICelera
Cytogenetic Map1q23.1NCBI
HuRef1130,026,881 - 130,027,855 (-)NCBIHuRef
CHM1_11160,065,480 - 160,066,454 (-)NCBICHM1_1
T2T-CHM13v2.01157,836,759 - 157,837,733 (-)NCBIT2T-CHM13v2.0
Or6k2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391173,986,288 - 173,987,333 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1173,983,199 - 173,989,761 (+)EnsemblGRCm39 Ensembl
GRCm381174,158,722 - 174,159,767 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,155,633 - 174,162,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv371176,088,853 - 176,089,898 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361175,995,450 - 175,996,415 (+)NCBIMGSCv36mm8
Celera1181,262,032 - 181,263,077 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map180.95NCBI
Or6k2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81388,721,361 - 88,722,326 (+)NCBIGRCr8
mRatBN7.21386,186,442 - 86,190,391 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1386,185,529 - 86,190,815 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1388,700,466 - 88,701,431 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01390,100,744 - 90,101,709 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01387,285,493 - 87,286,458 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01392,249,759 - 92,250,724 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1392,249,759 - 92,250,724 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01396,767,915 - 96,768,880 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41389,937,452 - 89,938,417 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11390,126,335 - 90,127,301 (+)NCBI
Celera1385,791,781 - 85,792,746 (+)NCBICelera
Cytogenetic Map13q24NCBI
LOC100981216
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2191,147,251 - 91,148,228 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1190,891,096 - 90,892,073 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01134,058,226 - 134,059,339 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11137,849,046 - 137,850,158 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1137,849,135 - 137,850,115 (-)Ensemblpanpan1.1panPan2
LOC103223778
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1205,221,383 - 5,224,559 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660384,390,507 - 4,391,761 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in OR6K2
46 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system respiratory system
High
Medium
Low
Below cutoff 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000018524   ⟹   ENSCAFP00000017157
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3823,043,721 - 23,044,686 (+)Ensembl
RefSeq Acc Id: NM_001388896   ⟹   NP_001375825
RefSeq Status: INFERRED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3823,065,822 - 23,066,787 (+)NCBI
ROS_Cfam_1.03823,175,283 - 23,176,248 (+)NCBI
UMICH_Zoey_3.13822,938,358 - 22,939,322 (+)NCBI
UNSW_CanFamBas_1.03823,473,085 - 23,474,050 (+)NCBI
UU_Cfam_GSD_1.03823,904,351 - 23,905,316 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001375825 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AEN80214 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000017157.3
  ENSCAFP00030041903.1
  ENSCAFP00040030361.1
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000017157   ⟸   ENSCAFT00000018524
RefSeq Acc Id: NP_001375825   ⟸   NM_001388896
- UniProtKB: G3FJB8 (UniProtKB/TrEMBL),   A0A8C0PHK4 (UniProtKB/TrEMBL)
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011678 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025936 UniProtKB/TrEMBL
  ENSCAFG00040018857 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000018524.3 UniProtKB/TrEMBL
  ENSCAFT00030047900.1 UniProtKB/TrEMBL
  ENSCAFT00040034868.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene LOC610561 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0PHK4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0T3X5_CANLF UniProtKB/TrEMBL
  G3FJB8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:97093 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-18 OR6K2  olfactory receptor family 6 subfamily K member 2  LOC610561  olfactory receptor 6K2  Symbol and/or name change 5135510 APPROVED
2017-09-12 LOC610561  olfactory receptor 6K2    olfactory receptor 6K2-like  Symbol and/or name change 5135510 APPROVED