WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial)

Gene: WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial) Canis lupus familiaris

Analyze

Symbol:

WARS2

Name:

tryptophanyl tRNA synthetase 2, mitochondrial

RGD ID:

12353404

Description:

ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); ATP binding (inferred); tryptophan-tRNA ligase activity (inferred); INVOLVED IN positive regulation of angiogenesis (ortholog); vasculogenesis (ortholog); PARTICIPATES IN tryptophan metabolic pathway; ASSOCIATED WITH genetic disease (ortholog); Hajdu-Cheney syndrome (ortholog); Mitochondrial Neurodevelopmental Disorder, with Abnormal Movements and Lactic Acidosis, with or without Seizures (ortholog); FOUND IN cytosol (inferred); mitochondrial matrix (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tryptophan--tRNA ligase, mitochondrial; tryptophanyl-tRNA synthetase, mitochondrial

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	56,229,175 - 56,322,688 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	56,229,769 - 56,322,638 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	55,877,127 - 55,971,652 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	57,100,900 - 57,195,725 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	57,100,941 - 57,195,693 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	56,136,854 - 56,231,602 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	56,169,008 - 56,263,812 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	56,758,810 - 56,853,584 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Hajdu-Cheney syndrome (ISO)

Mitochondrial Neurodevelopmental Disorder, with Abnormal Movements and Lactic Acidosis, with or without Seizures (ISO)

Parkinsonism-Dystonia, Childhood-Onset, 3 (ISO)

PHGDH deficiency (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mitochondrial tryptophanyl-tRNA aminoacylation (IEA)

positive regulation of angiogenesis (ISO)

translation (IEA)

tryptophanyl-tRNA aminoacylation (IEA)

vasculogenesis (IEA,ISO)

Cellular Component

cytosol (IEA)

mitochondrial matrix (IEA)

mitochondrion (IEA)

nucleoplasm (IEA)

plasma membrane (IEA)

Molecular Function

aminoacyl-tRNA ligase activity (IEA)

ATP binding (IEA)

tryptophan-tRNA ligase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

tryptophan metabolic pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

WARS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	56,229,175 - 56,322,688 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	56,229,769 - 56,322,638 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	55,877,127 - 55,971,652 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	57,100,900 - 57,195,725 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	57,100,941 - 57,195,693 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	56,136,854 - 56,231,602 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	56,169,008 - 56,263,812 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	56,758,810 - 56,853,584 (-)	NCBI		UU_Cfam_GSD_1.0

WARS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	119,031,216 - 119,140,672 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	119,031,216 - 119,140,654 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	119,573,839 - 119,683,295 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	119,375,362 - 119,484,818 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	119,285,882 - 119,395,329	NCBI
Celera	1	117,804,670 - 117,914,139 (-)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI
HuRef	1	117,432,899 - 117,542,355 (-)	NCBI		HuRef
CHM1_1	1	119,689,114 - 119,798,567 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	119,044,400 - 119,154,015 (-)	NCBI		T2T-CHM13v2.0

Wars2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	99,047,423 - 99,128,546 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	99,048,384 - 99,146,502 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	99,140,107 - 99,221,230 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	99,141,068 - 99,239,186 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	98,945,013 - 99,024,126 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	99,270,151 - 99,349,264 (+)	NCBI		MGSCv36	mm8
MGSCv36	3	99,350,466 - 99,429,579 (+)	NCBI		MGSCv36	mm8
Cytogenetic Map	3	F2.2	NCBI
cM Map	3	43.03	NCBI

Wars2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	189,150,322 - 189,233,606 (+)	NCBI		GRCr8
mRatBN7.2	2	186,459,744 - 186,543,581 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	186,459,444 - 186,543,571 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	194,125,237 - 194,209,552 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	191,938,946 - 192,023,252 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	186,757,892 - 186,841,864 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	201,170,363 - 201,256,115 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	201,172,312 - 201,255,703 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	220,638,872 - 220,721,873 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	193,819,862 - 193,902,421 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	178,941,140 - 179,020,771 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Wars2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	22,032,230 - 22,115,138 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955435	22,032,230 - 22,115,138 (-)	NCBI	ChiLan1.0	ChiLan1.0

WARS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	111,654,951 - 111,765,149 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	111,257,544 - 111,369,015 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	83,405,595 - 83,515,718 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	118,402,385 - 118,511,699 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	118,402,385 - 118,516,099 (+)	Ensembl	panpan1.1		panPan2

Wars2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	10,526,304 - 10,598,363 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936627	3,890,629 - 3,962,899 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936627	3,890,629 - 3,963,169 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

WARS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	101,787,583 - 101,883,070 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	101,787,585 - 101,881,231 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	111,920,791 - 111,924,709 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

WARS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	14,614,902 - 14,726,630 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	14,615,349 - 14,726,780 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	17,270,507 - 17,393,968 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Wars2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	14,654,403 - 14,735,315 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624772	14,652,874 - 14,735,732 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in WARS2
947 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	1
Low	4	5	22	6	6	6	6	6	12	8	10	6
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005630680	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038453177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038453178	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038453179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038453180	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038499345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038499346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038499347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038499348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038499349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561910	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561913	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038625984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038625985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038625986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038625987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038625989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038691912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038691913	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038691914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038691915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038691916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000205	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000359	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000015909 ⟹ ENSCAFP00000014717

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	17	56,229,769 - 56,322,638 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000079442 ⟹ ENSCAFP00000043474

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	17	56,229,769 - 56,274,638 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000087426 ⟹ ENSCAFP00000062816

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	17	56,229,769 - 56,322,638 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845010967 ⟹ ENSCAFP00845008559

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	17	57,100,941 - 57,195,693 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845010987 ⟹ ENSCAFP00845008576

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	17	57,100,941 - 57,195,664 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845011003 ⟹ ENSCAFP00845008587

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	17	57,100,941 - 57,148,088 (-)	Ensembl

RefSeq Acc Id:

XM_005630680 ⟹ XP_005630737

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	17	56,229,175 - 56,322,688 (-)	NCBI
Dog10K_Boxer_Tasha	17	55,877,127 - 55,971,652 (-)	NCBI

Sequence:

show sequence

GCTCTCCGGGCAGACGTCACTCAAGTCAGCGCGGCTCCGCCCCCTTCAAGATGGCGTTGCGCTC
AGTACGGAAGGCGCGTGGGTGCTGGAGCTTCATCCGGGCACTTCATAAAGGACCCGAAGCTGCT
CATGCTCCCCAGAAAGATGCTGTGAAGCGAGTATTCTCTGGCATTCAGCCTACAGGAATCCCCC
ACCTTGGCAATTACCTGGGAGCCATTGAGACCTGGGTGAAATTACAGGAAGAGCATGGCTCGGT
GCTGTACAGCATTGTTGACCTACACTCCATCACTGTCCCCCAGGACCCGGCCGTCCTTCGGCAG
AGCATCTTGGACATGACTGCTGTTCTTCTCGCCTGTGGCATAAACCCAGAGAAGAGTATCCTTT
TCCAACAATCTCAGGTGTCCGAACACACACAGTTAAGCTGGATCCTTACCTGCATGGTCAGACT
TCCCCGGTTACAGCATTTACACCAGTGGAAGGCAAAGATTGCCACGCAGAAGCATGGTGGAACT
GTGGGCCTGCTCACATACCCAGTGCTCCAGGCAGCGGACATCCTGTTATACAAGTCCACACACG
TTCCTGTCGGGGAGGATCAAGTCCAGCACATGGAGCTCGTTCAGGATCTAGCACAAGGGTTTAA
TAAGAAGTATGGAGAGGTCTTCCCCGTGCCCAGGTCCATTCTAACATCCATGAAGAAGGTGAAA
TCTCTCCGTGACCCTTCTGCCAAGATGTCAAAATCGGACCCTGATAAACTGGCCACCGTCAGGA
TAACAGACAGTCCAGAGGAGATCGTGCAGAAATTCCGCAAGGCTGTGACAGACTTCACATCAGA
GGTGACCTACGAGCCAGCCCGGCGAGCCGGGGTCTCTAACCTGGTGGCCATTCACGCAGCAGTG
GTCGGTGTCCCTGTGGAGGAAGCACTCCAGCACAGCGCAGGCCTGGACACTGCTCGCTACAAGC
TGCTGGTGGCCGATGCCGTGATTCAGAAATTTGCTCCGATTAAGAGTGAAATTGAAAAACTTAA
GACAGACAGGGGCCACTTAGAGAAGGTCTTACAGGTTGGGTCAGCAAAAGCTAGGGAATTAGCC
CATCCTGTGTGCCAGGAGGTGAAGAAATTGGTGGGGCTTCTGTAGGAAGCAAGGCTTTTATGAC
TTATGGCCTGTGCACGCCAATAAAGGCAGCCTTCCTCACAAATGAAAAATGATGGCTTGGGGAC
ATTTAATTTTGGTTCACCTGGCTTCATTTGAATATTGAATATTGGCTTCATTTGATAAATAAGG
ATTTGTAACCTTCAAATAGAGTGGTGTTCTAAATCCCATCAGCAAAATGCTGTGACCAAAAATA
ATAGAGAGAAGGCATGACTATCTGAATCCTCAATTATTTGAGGCACACTCCTTACCCTGAATTT
AGGTATATGAATGTGATTGAGGTGAGCGGTAGTTCAAACTCTCCTGCTCCACTGACTGAGCCGG
CCAGGTGCCCCTCTGTCCCAACCCTCTTAAAAAGTAAGACGGAGATTCTTAGACTTCTAATCCT
TGGGATGCCATTTGGACCAATTTGTATTGAAATCAACTTATAAAAATAAGTTGATTATTATAGC
TCCTTTGTCACTGAGATAGTACCTGCCTAAATGCATTTAAGCTGCTTTACTTGTTCCCAACAAG
ACCACACTGACTGTCCCAATAAGTATTGTTTTGTTCAATTCAGAAATACATGATATAGTCTTC

hide sequence

RefSeq Acc Id:

XM_038453177 ⟹ XP_038309105

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	17	55,877,127 - 55,971,629 (-)	NCBI

RefSeq Acc Id:

XM_038453178 ⟹ XP_038309106

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	17	55,877,127 - 55,971,255 (-)	NCBI

RefSeq Acc Id:

XM_038453179 ⟹ XP_038309107

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	17	55,877,127 - 55,971,255 (-)	NCBI

RefSeq Acc Id:

XM_038453180 ⟹ XP_038309108

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	17	55,879,243 - 55,971,652 (-)	NCBI

RefSeq Acc Id:

XM_038499345 ⟹ XP_038355273

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	17	56,136,854 - 56,231,602 (-)	NCBI

RefSeq Acc Id:

XM_038499346 ⟹ XP_038355274

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	17	56,136,854 - 56,231,579 (-)	NCBI

RefSeq Acc Id:

XM_038499347 ⟹ XP_038355275

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	17	56,136,854 - 56,231,205 (-)	NCBI

RefSeq Acc Id:

XM_038499348 ⟹ XP_038355276

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	17	56,136,854 - 56,231,205 (-)	NCBI

RefSeq Acc Id:

XM_038499349 ⟹ XP_038355277

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	17	56,138,979 - 56,231,602 (-)	NCBI

RefSeq Acc Id:

XM_038561910 ⟹ XP_038417838

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	17	56,758,810 - 56,853,584 (-)	NCBI

RefSeq Acc Id:

XM_038561912 ⟹ XP_038417840

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	17	56,758,810 - 56,853,561 (-)	NCBI

RefSeq Acc Id:

XM_038561913 ⟹ XP_038417841

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	17	56,758,810 - 56,853,187 (-)	NCBI

RefSeq Acc Id:

XM_038561914 ⟹ XP_038417842

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	17	56,758,810 - 56,853,187 (-)	NCBI

RefSeq Acc Id:

XM_038561915 ⟹ XP_038417843

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	17	56,760,926 - 56,853,584 (-)	NCBI

RefSeq Acc Id:

XM_038625984 ⟹ XP_038481912

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	17	56,169,008 - 56,263,812 (-)	NCBI

RefSeq Acc Id:

XM_038625985 ⟹ XP_038481913

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	17	56,169,008 - 56,263,789 (-)	NCBI

RefSeq Acc Id:

XM_038625986 ⟹ XP_038481914

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	17	56,169,008 - 56,263,415 (-)	NCBI

RefSeq Acc Id:

XM_038625987 ⟹ XP_038481915

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	17	56,169,008 - 56,263,415 (-)	NCBI

RefSeq Acc Id:

XM_038625989 ⟹ XP_038481917

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	17	56,171,124 - 56,263,812 (-)	NCBI

RefSeq Acc Id:

XM_038691912 ⟹ XP_038547840

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	17	57,100,900 - 57,195,725 (-)	NCBI

RefSeq Acc Id:

XM_038691913 ⟹ XP_038547841

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	17	57,100,900 - 57,195,702 (-)	NCBI

RefSeq Acc Id:

XM_038691914 ⟹ XP_038547842

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	17	57,100,900 - 57,195,328 (-)	NCBI

RefSeq Acc Id:

XM_038691915 ⟹ XP_038547843

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	17	57,100,900 - 57,195,328 (-)	NCBI

RefSeq Acc Id:

XM_038691916 ⟹ XP_038547844

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	17	57,103,020 - 57,195,725 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005630737	(Get FASTA)	NCBI Sequence Viewer
	XP_038309105	(Get FASTA)	NCBI Sequence Viewer
	XP_038309106	(Get FASTA)	NCBI Sequence Viewer
	XP_038309107	(Get FASTA)	NCBI Sequence Viewer
	XP_038309108	(Get FASTA)	NCBI Sequence Viewer
	XP_038355273	(Get FASTA)	NCBI Sequence Viewer
	XP_038355274	(Get FASTA)	NCBI Sequence Viewer
	XP_038355275	(Get FASTA)	NCBI Sequence Viewer
	XP_038355276	(Get FASTA)	NCBI Sequence Viewer
	XP_038355277	(Get FASTA)	NCBI Sequence Viewer
	XP_038417838	(Get FASTA)	NCBI Sequence Viewer
	XP_038417840	(Get FASTA)	NCBI Sequence Viewer
	XP_038417841	(Get FASTA)	NCBI Sequence Viewer
	XP_038417842	(Get FASTA)	NCBI Sequence Viewer
	XP_038417843	(Get FASTA)	NCBI Sequence Viewer
	XP_038481912	(Get FASTA)	NCBI Sequence Viewer
	XP_038481913	(Get FASTA)	NCBI Sequence Viewer
	XP_038481914	(Get FASTA)	NCBI Sequence Viewer
	XP_038481915	(Get FASTA)	NCBI Sequence Viewer
	XP_038481917	(Get FASTA)	NCBI Sequence Viewer
	XP_038547840	(Get FASTA)	NCBI Sequence Viewer
	XP_038547841	(Get FASTA)	NCBI Sequence Viewer
	XP_038547842	(Get FASTA)	NCBI Sequence Viewer
	XP_038547843	(Get FASTA)	NCBI Sequence Viewer
	XP_038547844	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000014717.3
	ENSCAFP00000043474.1
	ENSCAFP00000071157.1
	ENSCAFP00030010755.1
	ENSCAFP00030010783.1
	ENSCAFP00040022625.1
	ENSCAFP00040022678.1
	ENSCAFP00845008559
	ENSCAFP00845008559.1
	ENSCAFP00845008576
	ENSCAFP00845008576.1
	ENSCAFP00845008587.1

RefSeq Acc Id:	XP_005630737 ⟸ XM_005630680
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0R4S4 (UniProtKB/TrEMBL), A0A8C0YY21 (UniProtKB/TrEMBL), A0A8I3MZ22 (UniProtKB/TrEMBL), A0A8C0SJQ5 (UniProtKB/TrEMBL), A0A8I3MU10 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALRSVRKARGCWSFIRALHKGPEAAHAPQKDAVKRVFSGIQPTGIPHLGNYLGAIETWVKLQE EHGSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEHTQLSWILT CMVRLPRLQHLHQWKAKIATQKHGGTVGLLTYPVLQAADILLYKSTHVPVGEDQVQHMELVQDL AQGFNKKYGEVFPVPRSILTSMKKVKSLRDPSAKMSKSDPDKLATVRITDSPEEIVQKFRKAVT DFTSEVTYEPARRAGVSNLVAIHAAVVGVPVEEALQHSAGLDTARYKLLVADAVIQKFAPIKSE IEKLKTDRGHLEKVLQVGSAKARELAHPVCQEVKKLVGLL hide sequence

RefSeq Acc Id:

ENSCAFP00000014717 ⟸ ENSCAFT00000015909

RefSeq Acc Id:

ENSCAFP00000043474 ⟸ ENSCAFT00000079442

RefSeq Acc Id:

ENSCAFP00000062816 ⟸ ENSCAFT00000087426

RefSeq Acc Id:	XP_038355273 ⟸ XM_038499345
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038355274 ⟸ XM_038499346
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038355275 ⟸ XM_038499347
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038355276 ⟸ XM_038499348
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038355277 ⟸ XM_038499349
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038481912 ⟸ XM_038625984
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038481913 ⟸ XM_038625985
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038481914 ⟸ XM_038625986
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038481915 ⟸ XM_038625987
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038481917 ⟸ XM_038625989
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_038547840 ⟸ XM_038691912
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0R4S4 (UniProtKB/TrEMBL), A0A8C0YY21 (UniProtKB/TrEMBL), A0A8I3MZ22 (UniProtKB/TrEMBL), A0A8C0SJQ5 (UniProtKB/TrEMBL), A0A8I3MU10 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038547841 ⟸ XM_038691913
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3N4D9 (UniProtKB/TrEMBL), A0A8P0PLR8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038547842 ⟸ XM_038691914
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038547843 ⟸ XM_038691915
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038547844 ⟸ XM_038691916
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038309105 ⟸ XM_038453177
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3N4D9 (UniProtKB/TrEMBL), A0A8P0PLR8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038309106 ⟸ XM_038453178
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038309107 ⟸ XM_038453179
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038309108 ⟸ XM_038453180
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038417838 ⟸ XM_038561910
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3MU10 (UniProtKB/TrEMBL), A0A8I3MZ22 (UniProtKB/TrEMBL), A0A8C0R4S4 (UniProtKB/TrEMBL), A0A8C0SJQ5 (UniProtKB/TrEMBL), A0A8C0YY21 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038417840 ⟸ XM_038561912
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3N4D9 (UniProtKB/TrEMBL), A0A8P0PLR8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038417841 ⟸ XM_038561913
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038417842 ⟸ XM_038561914
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038417843 ⟸ XM_038561915
- Peptide Label:	isoform X4

RefSeq Acc Id:

ENSCAFP00845008587 ⟸ ENSCAFT00845011003

RefSeq Acc Id:

ENSCAFP00845008576 ⟸ ENSCAFT00845010987

RefSeq Acc Id:

ENSCAFP00845008559 ⟸ ENSCAFT00845010967

Promoters

RGD ID:

13686351

Promoter ID:

EPDNEW_C4418

Type:

single initiation site

Name:

WARS2_1

Description:

tryptophanyl tRNA synthetase 2, mitochondrial

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	17	56,322,645 - 56,322,705	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000009996	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030006682	UniProtKB/TrEMBL
	ENSCAFG00040014098	UniProtKB/TrEMBL
	ENSCAFG00845006189	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000015909.5	UniProtKB/TrEMBL
	ENSCAFT00000079442.2	UniProtKB/TrEMBL
	ENSCAFT00000097516.1	UniProtKB/TrEMBL
	ENSCAFT00030012291.1	UniProtKB/TrEMBL
	ENSCAFT00030012321.1	UniProtKB/TrEMBL
	ENSCAFT00040026014.1	UniProtKB/TrEMBL
	ENSCAFT00040026073.1	UniProtKB/TrEMBL
	ENSCAFT00845010967	ENTREZGENE
	ENSCAFT00845010967.1	UniProtKB/TrEMBL
	ENSCAFT00845010987	ENTREZGENE
	ENSCAFT00845010987.1	UniProtKB/TrEMBL
	ENSCAFT00845011003.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.620	UniProtKB/TrEMBL
	Tyrosyl-Transfer RNA Synthetase	UniProtKB/TrEMBL
InterPro	aa-tRNA-synth_I_CS	UniProtKB/TrEMBL
	aa-tRNA-synth_Ic	UniProtKB/TrEMBL
	Rossmann-like_a/b/a_fold	UniProtKB/TrEMBL
	Trp-tRNA-ligase	UniProtKB/TrEMBL
	Trp-tRNA-ligase_bac-type	UniProtKB/TrEMBL
KEGG Report	cfa:483145	UniProtKB/TrEMBL
NCBI Gene	WARS2	ENTREZGENE
PANTHER	TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL	UniProtKB/TrEMBL
	TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL	UniProtKB/TrEMBL
Pfam	tRNA-synt_1b	UniProtKB/TrEMBL
PRINTS	TRNASYNTHTRP	UniProtKB/TrEMBL
PROSITE	AA_TRNA_LIGASE_I	UniProtKB/TrEMBL
Superfamily-SCOP	Nucleotidylyl transferase	UniProtKB/TrEMBL
UniProt	A0A8C0R4S4	ENTREZGENE
	A0A8C0SJQ5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0YY21	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MU10	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MZ22	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3N4D9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0PLR8	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:48332	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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