ACAA2 (acetyl-CoA acyltransferase 2) - Rat Genome Database

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Gene: ACAA2 (acetyl-CoA acyltransferase 2) Canis lupus familiaris
Analyze
Symbol: ACAA2
Name: acetyl-CoA acyltransferase 2
RGD ID: 12349882
Description: ENCODES a protein that exhibits acetyl-CoA C-acetyltransferase activity (ortholog); acetyl-CoA C-acyltransferase activity (ortholog); acyl-CoA hydrolase activity (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); cellular response to hypoxia (ortholog); fatty acid beta-oxidation (ortholog); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; ASSOCIATED WITH adult respiratory distress syndrome (ortholog); intellectual disability (ortholog); osteoarthritis (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH clofibrate; phenobarbital
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 3-ketoacyl-CoA thiolase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1779,028,636 - 79,057,720 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha778,425,399 - 78,464,609 (+)NCBI
ROS_Cfam_1.0779,086,363 - 79,125,478 (+)NCBI
ROS_Cfam_1.0 Ensembl779,086,417 - 79,125,474 (+)Ensembl
UMICH_Zoey_3.1778,802,328 - 78,841,679 (+)NCBI
UNSW_CanFamBas_1.0778,830,801 - 78,869,895 (+)NCBI
UU_Cfam_GSD_1.0779,116,676 - 79,155,898 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
ACAA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1779,028,636 - 79,057,720 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha778,425,399 - 78,464,609 (+)NCBI
ROS_Cfam_1.0779,086,363 - 79,125,478 (+)NCBI
ROS_Cfam_1.0 Ensembl779,086,417 - 79,125,474 (+)Ensembl
UMICH_Zoey_3.1778,802,328 - 78,841,679 (+)NCBI
UNSW_CanFamBas_1.0778,830,801 - 78,869,895 (+)NCBI
UU_Cfam_GSD_1.0779,116,676 - 79,155,898 (+)NCBI
ACAA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381849,782,164 - 49,813,533 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1849,782,164 - 49,813,953 (-)EnsemblGRCh38hg38GRCh38
GRCh371847,308,534 - 47,339,903 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361845,563,873 - 45,593,900 (-)NCBINCBI36hg18NCBI36
Build 341845,563,872 - 45,593,900NCBI
Celera1844,166,539 - 44,196,918 (-)NCBI
Cytogenetic Map18q21.1NCBI
HuRef1844,164,298 - 44,194,528 (-)NCBIHuRef
CHM1_11847,305,498 - 47,335,866 (-)NCBICHM1_1
T2T-CHM13v2.01849,981,292 - 50,015,307 (-)NCBI
Acaa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391874,912,283 - 74,939,278 (+)NCBIGRCm39mm39
GRCm39 Ensembl1874,912,268 - 74,939,279 (+)Ensembl
GRCm381874,779,212 - 74,806,207 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1874,779,197 - 74,806,208 (+)EnsemblGRCm38mm10GRCm38
MGSCv371874,938,866 - 74,965,861 (+)NCBIGRCm37mm9NCBIm37
MGSCv361874,904,577 - 74,931,572 (+)NCBImm8
Celera1876,003,491 - 76,030,308 (+)NCBICelera
Cytogenetic Map18E2NCBI
cM Map1850.76NCBI
Acaa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21868,345,136 - 68,373,246 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1868,345,012 - 68,373,249 (+)Ensembl
Rnor_6.01870,733,872 - 70,762,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,733,872 - 70,762,395 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01869,873,084 - 69,901,836 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41871,587,259 - 71,632,610 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11871,660,459 - 71,705,811 (+)NCBI
Celera1866,521,595 - 66,549,734 (+)NCBICelera
Cytogenetic Map18q12.2NCBI
Acaa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540234,857,317 - 34,885,169 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540234,857,317 - 34,885,169 (-)NCBIChiLan1.0ChiLan1.0
ACAA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11846,512,374 - 46,542,737 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1846,512,374 - 46,542,737 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01843,164,504 - 43,195,038 (-)NCBIMhudiblu_PPA_v0panPan3
Acaa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494438,003,267 - 38,029,972 (+)NCBI
SpeTri2.0NW_00493649713,242,644 - 13,269,007 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACAA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl199,284,140 - 99,311,321 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1199,284,467 - 99,310,759 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21108,842,950 - 108,869,736 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACAA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11831,152,067 - 31,181,020 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1831,152,074 - 31,181,706 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660505,299,842 - 5,328,903 (+)NCBIVero_WHO_p1.0
Acaa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477813,307,094 - 13,336,120 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462477813,307,236 - 13,336,347 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022421730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038543977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038543978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038579126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038579135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038672784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038672785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00845028583   ⟹   ENSCAFP00845022488
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl779,086,417 - 79,125,469 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845028618   ⟹   ENSCAFP00845022522
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl779,086,672 - 79,125,474 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845028653   ⟹   ENSCAFP00845022552
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl779,091,500 - 79,125,474 (+)Ensembl
RefSeq Acc Id: XM_038482508   ⟹   XP_038338436
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1778,802,557 - 78,841,679 (+)NCBI
RefSeq Acc Id: XM_038482509   ⟹   XP_038338437
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1778,802,328 - 78,841,679 (+)NCBI
RefSeq Acc Id: XM_038543977   ⟹   XP_038399905
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0779,116,906 - 79,155,898 (+)NCBI
RefSeq Acc Id: XM_038543978   ⟹   XP_038399906
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0779,116,676 - 79,155,898 (+)NCBI
RefSeq Acc Id: XM_038579126   ⟹   XP_038435054
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha778,425,656 - 78,464,609 (+)NCBI
RefSeq Acc Id: XM_038579135   ⟹   XP_038435063
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha778,425,399 - 78,464,609 (+)NCBI
RefSeq Acc Id: XM_038608076   ⟹   XP_038464004
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0778,831,031 - 78,869,895 (+)NCBI
RefSeq Acc Id: XM_038608077   ⟹   XP_038464005
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0778,830,801 - 78,869,895 (+)NCBI
RefSeq Acc Id: XM_038672784   ⟹   XP_038528712
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0779,086,620 - 79,125,478 (+)NCBI
RefSeq Acc Id: XM_038672785   ⟹   XP_038528713
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0779,086,363 - 79,125,478 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_038338437   ⟸   XM_038482509
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038338436   ⟸   XM_038482508
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038464005   ⟸   XM_038608077
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038464004   ⟸   XM_038608076
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038528713   ⟸   XM_038672785
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038528712   ⟸   XM_038672784
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038435063   ⟸   XM_038579135
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038435054   ⟸   XM_038579126
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038399906   ⟸   XM_038543978
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038399905   ⟸   XM_038543977
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCAFP00845022488   ⟸   ENSCAFT00845028583
RefSeq Acc Id: ENSCAFP00845022522   ⟸   ENSCAFT00845028618
RefSeq Acc Id: ENSCAFP00845022552   ⟸   ENSCAFT00845028653
Protein Domains
Thiolase_C   Thiolase_N


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00845016064 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00845022488 ENTREZGENE
  ENSCAFP00845022488.1 UniProtKB/TrEMBL
  ENSCAFP00845022522 ENTREZGENE
  ENSCAFP00845022522.1 UniProtKB/TrEMBL
  ENSCAFP00845022552.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845028583 ENTREZGENE
  ENSCAFT00845028583.1 UniProtKB/TrEMBL
  ENSCAFT00845028618 ENTREZGENE
  ENSCAFT00845028618.1 UniProtKB/TrEMBL
  ENSCAFT00845028653.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.47.10 UniProtKB/TrEMBL
InterPro Thiolase UniProtKB/TrEMBL
  Thiolase-like UniProtKB/TrEMBL
  Thiolase_acyl_enz_int_AS UniProtKB/TrEMBL
  Thiolase_AS UniProtKB/TrEMBL
  Thiolase_C UniProtKB/TrEMBL
  Thiolase_CS UniProtKB/TrEMBL
  Thiolase_N UniProtKB/TrEMBL
NCBI Gene ACAA2 ENTREZGENE
Pfam Thiolase_C UniProtKB/TrEMBL
  Thiolase_N UniProtKB/TrEMBL
PIRSF Ac-CoA_Ac_transf UniProtKB/TrEMBL
PROSITE THIOLASE_1 UniProtKB/TrEMBL
  THIOLASE_2 UniProtKB/TrEMBL
  THIOLASE_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF53901 UniProtKB/TrEMBL
TIGRFAMs AcCoA-C-Actrans UniProtKB/TrEMBL
UniProt A0A8I3NNE3_CANLF UniProtKB/TrEMBL
  A0A8I3NU61_CANLF UniProtKB/TrEMBL
  A0A8I3RZ46_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:53324 ENTREZGENE