DRC12 (dynein regulatory complex subunit 12 homolog) - Rat Genome Database

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Gene: DRC12 (dynein regulatory complex subunit 12 homolog) Canis lupus familiaris
Analyze
Symbol: DRC12 (Ensembl: CCDC153)
Name: dynein regulatory complex subunit 12 homolog
RGD ID: 12349200
Description: ENCODES a protein that exhibits identical protein binding (ortholog); ASSOCIATED WITH CD3epsilon deficiency (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); congenital disorder of glycosylation Ij (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CCDC153; coiled-coil domain containing 153; coiled-coil domain-containing protein 153
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,679,180 - 14,686,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,682,004 - 14,686,150 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,732,289 - 14,739,554 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,622,549 - 14,629,813 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,625,373 - 14,629,410 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,760,641 - 14,767,897 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,664,839 - 14,672,096 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,705,049 - 14,712,309 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Genomics

Comparative Map Data
DRC12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,679,180 - 14,686,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,682,004 - 14,686,150 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,732,289 - 14,739,554 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,622,549 - 14,629,813 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,625,373 - 14,629,410 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,760,641 - 14,767,897 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,664,839 - 14,672,096 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,705,049 - 14,712,309 (+)NCBIUU_Cfam_GSD_1.0
DRC12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,190,254 - 119,195,841 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11119,190,250 - 119,196,769 (-)EnsemblGRCh38hg38GRCh38
GRCh3711119,060,963 - 119,066,551 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,566,189 - 118,569,381 (-)NCBINCBI36Build 36hg18NCBI36
Celera11116,220,804 - 116,221,252 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11115,000,427 - 115,006,050 (-)NCBIHuRef
CHM1_111118,947,230 - 118,952,849 (-)NCBICHM1_1
T2T-CHM13v2.011119,210,624 - 119,216,213 (-)NCBIT2T-CHM13v2.0
Ccdc153
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,151,961 - 44,158,240 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,151,973 - 44,158,603 (+)EnsemblGRCm39 Ensembl
GRCm38944,240,677 - 44,247,306 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,240,676 - 44,247,306 (+)EnsemblGRCm38mm10GRCm38
MGSCv37944,048,760 - 44,055,389 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36944,497,931 - 44,504,796 (+)NCBIMGSCv36mm8
MGSCv36943,991,671 - 43,998,301 (+)NCBIMGSCv36mm8
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Drc12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8853,468,344 - 53,481,168 (+)NCBIGRCr8
mRatBN7.2844,576,528 - 44,584,345 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,577,836 - 44,584,338 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,073,020 - 50,079,523 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0848,351,738 - 48,358,241 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,222,586 - 46,229,110 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0848,570,718 - 48,577,856 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,569,328 - 48,577,855 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,189,371 - 47,196,430 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,218,487 - 47,225,173 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,227,252 - 47,233,938 (+)NCBI
Celera844,164,556 - 44,171,061 (+)NCBICelera
Cytogenetic Map8q22NCBI
Drc12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,292,769 - 20,297,053 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,292,619 - 20,297,902 (-)NCBIChiLan1.0ChiLan1.0
DRC12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,894,971 - 119,901,311 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,998,652 - 121,004,918 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011114,028,927 - 114,034,620 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,956,940 - 117,962,655 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,956,945 - 117,962,655 (-)Ensemblpanpan1.1panPan2
Drc12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947101,204,043 - 101,210,114 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365424,126,890 - 4,131,179 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365424,127,054 - 4,131,148 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRC12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,397,081 - 46,411,758 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,406,085 - 46,412,449 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,442,116 - 51,446,971 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DRC12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,566,126 - 110,572,800 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,566,174 - 110,571,880 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604315,462,167 - 15,467,776 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Drc12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,568,858 - 14,572,508 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478414,568,801 - 14,572,498 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DRC12
108 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 3 6 1
Low 4 3 4 3 8 5
Below cutoff 1 5 13 6 2 6 6 6 4 6

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005619677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022418211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022418212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022418213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022418214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038508378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002626414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000037124   ⟹   ENSCAFP00000032577
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl514,682,004 - 14,686,043 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000047493   ⟹   ENSCAFP00000038044
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl514,682,004 - 14,686,150 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845000386   ⟹   ENSCAFP00845000263
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl514,625,373 - 14,629,410 (+)Ensembl
RefSeq Acc Id: XM_005619677   ⟹   XP_005619734
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1514,679,189 - 14,686,446 (+)NCBI
Dog10K_Boxer_Tasha514,732,303 - 14,739,554 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022418213   ⟹   XP_022273921
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1514,679,180 - 14,686,446 (+)NCBI
Dog10K_Boxer_Tasha514,732,289 - 14,738,686 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038474791   ⟹   XP_038330719
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1514,760,641 - 14,767,029 (+)NCBI
RefSeq Acc Id: XM_038474792   ⟹   XP_038330720
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1514,760,655 - 14,767,897 (+)NCBI
RefSeq Acc Id: XM_038474793   ⟹   XP_038330721
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1514,760,649 - 14,767,897 (+)NCBI
RefSeq Acc Id: XM_038508378   ⟹   XP_038364306
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha514,732,297 - 14,739,554 (+)NCBI
RefSeq Acc Id: XM_038535938   ⟹   XP_038391866
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0514,705,063 - 14,712,309 (+)NCBI
RefSeq Acc Id: XM_038535939   ⟹   XP_038391867
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0514,705,049 - 14,711,442 (+)NCBI
RefSeq Acc Id: XM_038535940   ⟹   XP_038391868
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0514,705,057 - 14,712,309 (+)NCBI
RefSeq Acc Id: XM_038600133   ⟹   XP_038456061
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0514,664,839 - 14,671,228 (+)NCBI
RefSeq Acc Id: XM_038600134   ⟹   XP_038456062
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0514,664,853 - 14,672,096 (+)NCBI
RefSeq Acc Id: XM_038600135   ⟹   XP_038456063
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0514,664,847 - 14,672,096 (+)NCBI
RefSeq Acc Id: XM_038664671   ⟹   XP_038520599
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,622,563 - 14,629,813 (+)NCBI
RefSeq Acc Id: XM_038664672   ⟹   XP_038520600
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,622,549 - 14,628,945 (+)NCBI
RefSeq Acc Id: XM_038664673   ⟹   XP_038520601
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,622,557 - 14,629,813 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005619734   ⟸   XM_005619677
- Peptide Label: isoform X2
- UniProtKB: A0A8C0T7V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022273921   ⟸   XM_022418213
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000032577   ⟸   ENSCAFT00000037124
RefSeq Acc Id: ENSCAFP00000038044   ⟸   ENSCAFT00000047493
RefSeq Acc Id: XP_038330719   ⟸   XM_038474791
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038330721   ⟸   XM_038474793
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038330720   ⟸   XM_038474792
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038456061   ⟸   XM_038600133
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038456063   ⟸   XM_038600135
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038456062   ⟸   XM_038600134
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038520600   ⟸   XM_038664672
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038520601   ⟸   XM_038664673
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038520599   ⟸   XM_038664671
- Peptide Label: isoform X2
- UniProtKB: A0A8C0T7V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038364306   ⟸   XM_038508378
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038391867   ⟸   XM_038535939
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038391868   ⟸   XM_038535940
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038391866   ⟸   XM_038535938
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCAFP00845000263   ⟸   ENSCAFT00845000386


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000023966 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040019702 UniProtKB/TrEMBL
  ENSCAFG00845000259 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000037124.4 UniProtKB/TrEMBL
  ENSCAFT00040036410.1 UniProtKB/TrEMBL
  ENSCAFT00845000386.1 UniProtKB/TrEMBL
InterPro CCDC153 UniProtKB/TrEMBL
KEGG Report cfa:100683773 UniProtKB/TrEMBL
NCBI Gene CCDC153 ENTREZGENE
PANTHER COILED-COIL DOMAIN-CONTAINING PROTEIN 153 UniProtKB/TrEMBL
  PTHR28656 UniProtKB/TrEMBL
UniProt A0A8C0T7V6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MAA7_CANLF UniProtKB/TrEMBL
  A0A8P0SQ89_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:38803 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-12-25 DRC12  dynein regulatory complex subunit 12 homolog  CCDC153  coiled-coil domain containing 153  Symbol and/or name change 19259463 PROVISIONAL