MIR129-1 (microRNA mir-129-1) - Rat Genome Database

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Gene: MIR129-1 (microRNA mir-129-1) Canis lupus familiaris
Analyze
Symbol: MIR129-1
Name: microRNA mir-129-1 (Ensembl:microRNA 129-1)
RGD ID: 12348413
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-129-1; microRNA 129-1
RGD Orthologs
Human
Mouse
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,165,110 - 8,165,174 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,165,107 - 8,165,179 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha147,851,686 - 7,851,750 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0147,932,070 - 7,932,134 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1148,136,527 - 8,136,591 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,877,382 - 7,877,446 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,024,123 - 8,024,187 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:18392026  


Genomics

Comparative Map Data
MIR129-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,165,110 - 8,165,174 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,165,107 - 8,165,179 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha147,851,686 - 7,851,750 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0147,932,070 - 7,932,134 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1148,136,527 - 8,136,591 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,877,382 - 7,877,446 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,024,123 - 8,024,187 (-)NCBIUU_Cfam_GSD_1.0
MIR129-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387128,207,872 - 128,207,943 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7128,207,872 - 128,207,943 (+)EnsemblGRCh38hg38GRCh38
GRCh377127,847,925 - 127,847,996 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367127,635,160 - 127,635,231 (+)NCBINCBI36Build 36hg18NCBI36
Celera7122,651,214 - 122,651,285 (+)NCBICelera
Cytogenetic Map7q32.1NCBI
HuRef7122,208,895 - 122,208,966 (+)NCBIHuRef
CHM1_17127,781,240 - 127,781,311 (+)NCBICHM1_1
T2T-CHM13v2.07129,519,359 - 129,519,430 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27127,231,050 - 127,231,121 (+)NCBI
Mir129-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39629,022,618 - 29,022,690 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl629,022,618 - 29,022,690 (+)EnsemblGRCm39 Ensembl
GRCm38629,022,619 - 29,022,691 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl629,022,619 - 29,022,691 (+)EnsemblGRCm38mm10GRCm38
MGSCv37628,972,619 - 28,972,691 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera629,025,311 - 29,025,383 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.28NCBI
Mir129-1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8458,589,711 - 58,589,782 (+)NCBIGRCr8
mRatBN7.2457,624,295 - 57,624,366 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl457,624,295 - 57,624,366 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx462,607,065 - 62,607,136 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0458,523,476 - 58,523,547 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0456,925,108 - 56,925,179 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0456,301,726 - 56,301,797 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl456,301,726 - 56,301,797 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0456,049,095 - 56,049,166 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera452,735,670 - 52,735,741 (+)NCBICelera
Cytogenetic Map4q22NCBI
MIR129B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1820,157,213 - 20,157,296 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11820,157,213 - 20,157,296 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21821,181,553 - 21,181,636 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system nervous system reproductive system
High
Medium
Low 1 1 5
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000032606
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl148,165,107 - 8,165,179 (-)Ensembl
RefSeq Acc Id: NR_049250
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1148,165,110 - 8,165,174 (-)NCBI
Dog10K_Boxer_Tasha147,851,686 - 7,851,750 (-)NCBI
ROS_Cfam_1.0147,932,070 - 7,932,134 (-)NCBI
UMICH_Zoey_3.1148,136,527 - 8,136,591 (-)NCBI
UNSW_CanFamBas_1.0147,877,382 - 7,877,446 (-)NCBI
UU_Cfam_GSD_1.0148,024,123 - 8,024,187 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020499 Ensembl
  ENSCAFG00845025201 ENTREZGENE
Ensembl Transcript ENSCAFT00845044458 ENTREZGENE
miRBase MI0008019 ENTREZGENE
NCBI Gene MIR129-1 ENTREZGENE
RNAcentral URS00004E1410 RNACentral
  URS00007E39C7 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR129-1  microRNA mir-129-1    microRNA 129-1  Symbol and/or name change 5135510 APPROVED