CA7 (carbonic anhydrase 7) - Rat Genome Database

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Gene: CA7 (carbonic anhydrase 7) Canis lupus familiaris
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Symbol: CA7
Name: carbonic anhydrase 7
RGD ID: 12346958
Description: ENCODES a protein that exhibits carbonate dehydratase activity (inferred); zinc ion binding (inferred); INVOLVED IN positive regulation of cellular pH reduction (ortholog); positive regulation of synaptic transmission, GABAergic (ortholog); regulation of chloride transport (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,446,239 - 82,455,445 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,446,246 - 82,455,590 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha582,434,936 - 82,444,145 (-)NCBI
ROS_Cfam_1.0582,882,872 - 82,892,083 (-)NCBI
UMICH_Zoey_3.1582,706,026 - 82,715,234 (-)NCBI
UNSW_CanFamBas_1.0582,392,889 - 82,402,094 (-)NCBI
UU_Cfam_GSD_1.0583,031,862 - 83,041,073 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
CA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,446,239 - 82,455,445 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,446,246 - 82,455,590 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha582,434,936 - 82,444,145 (-)NCBI
ROS_Cfam_1.0582,882,872 - 82,892,083 (-)NCBI
UMICH_Zoey_3.1582,706,026 - 82,715,234 (-)NCBI
UNSW_CanFamBas_1.0582,392,889 - 82,402,094 (-)NCBI
UU_Cfam_GSD_1.0583,031,862 - 83,041,073 (-)NCBI
CA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1666,844,414 - 66,854,153 (+)EnsemblGRCh38hg38GRCh38
GRCh381666,844,414 - 66,854,149 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371666,878,317 - 66,888,050 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,435,783 - 65,445,551 (+)NCBINCBI36hg18NCBI36
Build 341665,435,891 - 65,445,541NCBI
Celera1651,386,593 - 51,396,359 (+)NCBI
Cytogenetic Map16q22.1NCBI
HuRef1652,752,480 - 52,762,235 (+)NCBIHuRef
CHM1_11668,285,378 - 68,295,146 (+)NCBICHM1_1
Car7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398105,261,326 - 105,276,979 (+)NCBIGRCm39mm39
GRCm39 Ensembl8105,261,321 - 105,276,975 (+)Ensembl
GRCm388104,534,694 - 104,550,347 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8104,534,689 - 104,550,343 (+)EnsemblGRCm38mm10GRCm38
MGSCv378107,064,707 - 107,074,243 (+)NCBIGRCm37mm9NCBIm37
MGSCv368107,429,936 - 107,439,472 (+)NCBImm8
Celera8108,773,242 - 108,782,734 (+)NCBICelera
Cytogenetic Map8D3NCBI
Car7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.219429,063 - 438,478 (-)NCBI
Rnor_6.0 Ensembl19636,545 - 645,937 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.019636,545 - 645,935 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.019630,356 - 639,746 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.419365,680 - 375,074 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.119365,695 - 375,513 (-)NCBI
Celera19424,600 - 433,992 (-)NCBICelera
Cytogenetic Map19p14NCBI
Ca7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543323,365,718 - 23,374,548 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543323,365,832 - 23,374,517 (+)NCBIChiLan1.0ChiLan1.0
CA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11666,262,259 - 66,272,316 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1666,262,362 - 66,271,665 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01647,161,021 - 47,170,800 (+)NCBIMhudiblu_PPA_v0panPan3
Ca7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934942,469,000 - 42,477,123 (-)NCBI
SpeTri2.0NW_00493647517,112,004 - 17,120,105 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,548,706 - 27,563,861 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1627,548,647 - 27,563,966 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CA7
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1552,541,008 - 52,551,307 (+)NCBI
ChlSab1.1 Ensembl552,541,527 - 52,551,389 (+)Ensembl
Ca7
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474619,640,436 - 19,648,708 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 6
Low 4 1
Below cutoff 5 18 6 6 6 5 5 6 8 10 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000032483   ⟹   ENSCAFP00000030251
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl582,446,246 - 82,455,590 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000043866   ⟹   ENSCAFP00000039305
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl582,446,246 - 82,454,991 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000075042   ⟹   ENSCAFP00000062018
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl582,446,246 - 82,454,991 (-)Ensembl
RefSeq Acc Id: XM_005620868   ⟹   XP_005620925
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1582,446,239 - 82,455,445 (-)NCBI
Dog10K_Boxer_Tasha582,434,936 - 82,444,145 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038477526   ⟹   XP_038333454
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1582,706,026 - 82,715,234 (-)NCBI
RefSeq Acc Id: XM_038477528   ⟹   XP_038333456
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1582,706,026 - 82,715,234 (-)NCBI
RefSeq Acc Id: XM_038538748   ⟹   XP_038394676
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0583,031,862 - 83,041,073 (-)NCBI
RefSeq Acc Id: XM_038538749   ⟹   XP_038394677
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0583,031,862 - 83,041,073 (-)NCBI
RefSeq Acc Id: XM_038602849   ⟹   XP_038458777
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0582,392,889 - 82,402,094 (-)NCBI
RefSeq Acc Id: XM_038602850   ⟹   XP_038458778
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0582,392,889 - 82,402,094 (-)NCBI
RefSeq Acc Id: XM_038667453   ⟹   XP_038523381
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0582,882,872 - 82,892,083 (-)NCBI
RefSeq Acc Id: XM_038667454   ⟹   XP_038523382
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0582,882,872 - 82,892,083 (-)NCBI
RefSeq Acc Id: XM_546892   ⟹   XP_546892
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1582,446,239 - 82,455,443 (-)NCBI
Dog10K_Boxer_Tasha582,434,936 - 82,444,145 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005620925   ⟸   XM_005620868
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_546892   ⟸   XM_546892
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000039305   ⟸   ENSCAFT00000043866
RefSeq Acc Id: ENSCAFP00000062018   ⟸   ENSCAFT00000075042
RefSeq Acc Id: ENSCAFP00000030251   ⟸   ENSCAFT00000032483
RefSeq Acc Id: XP_038333456   ⟸   XM_038477528
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038333454   ⟸   XM_038477526
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038458778   ⟸   XM_038602850
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038458777   ⟸   XM_038602849
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038523382   ⟸   XM_038667454
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038523381   ⟸   XM_038667453
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038394677   ⟸   XM_038538749
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038394676   ⟸   XM_038538748
- Peptide Label: isoform X1
Protein Domains
Alpha-carbonic anhydrase

Promoters
RGD ID:13683486
Promoter ID:EPDNEW_C1554
Type:single initiation site
Name:CA7_1
Description:carbonic anhydrase 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1582,455,394 - 82,455,454EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020399 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000030251 UniProtKB/TrEMBL
  ENSCAFP00000039305 UniProtKB/TrEMBL
  ENSCAFP00000062018 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000032483 UniProtKB/TrEMBL
  ENSCAFT00000043866 UniProtKB/TrEMBL
  ENSCAFT00000075042 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro alpha_CA_VII UniProtKB/TrEMBL
  Carbonic_anhydrase_a UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
  Carbonic_anhydrase_a_sf UniProtKB/TrEMBL
NCBI Gene CA7 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A5F4D6E2_CANLF UniProtKB/TrEMBL
  E2REU3_CANLF UniProtKB/TrEMBL
  J9P181_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:38615 ENTREZGENE