MCM3 (minichromosome maintenance complex component 3) - Rat Genome Database

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Gene: MCM3 (minichromosome maintenance complex component 3) Canis lupus familiaris
Analyze
Symbol: MCM3
Name: minichromosome maintenance complex component 3
RGD ID: 12343830
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN DNA unwinding involved in DNA replication (ortholog); ASSOCIATED WITH Meier-Gorlin syndrome (ortholog); FOUND IN centrosome (ortholog); CMG complex (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA replication licensing factor MCM3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11219,924,017 - 19,945,576 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1219,920,210 - 19,945,605 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1219,821,166 - 19,842,529 (-)NCBI
ROS_Cfam_1.01220,422,999 - 20,444,648 (-)NCBI
UMICH_Zoey_3.11219,928,809 - 19,950,166 (-)NCBI
UNSW_CanFamBas_1.01220,031,993 - 20,053,341 (-)NCBI
UU_Cfam_GSD_1.01220,170,450 - 20,191,818 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:19368124  


Genomics

Comparative Map Data
MCM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11219,924,017 - 19,945,576 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1219,920,210 - 19,945,605 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1219,821,166 - 19,842,529 (-)NCBI
ROS_Cfam_1.01220,422,999 - 20,444,648 (-)NCBI
UMICH_Zoey_3.11219,928,809 - 19,950,166 (-)NCBI
UNSW_CanFamBas_1.01220,031,993 - 20,053,341 (-)NCBI
UU_Cfam_GSD_1.01220,170,450 - 20,191,818 (-)NCBI
MCM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl652,264,014 - 52,284,881 (-)EnsemblGRCh38hg38GRCh38
GRCh38652,264,015 - 52,284,742 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37652,128,813 - 52,149,540 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36652,236,771 - 52,257,541 (-)NCBINCBI36hg18NCBI36
Build 34652,236,770 - 52,257,541NCBI
Celera653,789,937 - 53,810,711 (-)NCBI
Cytogenetic Map6p12.2NCBI
HuRef651,960,041 - 51,980,910 (-)NCBIHuRef
CHM1_1652,131,052 - 52,151,919 (-)NCBICHM1_1
Mcm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39120,873,188 - 20,890,536 (-)NCBIGRCm39mm39
GRCm39 Ensembl120,873,192 - 20,890,536 (-)Ensembl
GRCm38120,802,966 - 20,820,312 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl120,802,968 - 20,820,312 (-)EnsemblGRCm38mm10GRCm38
MGSCv37120,793,095 - 20,810,294 (-)NCBIGRCm37mm9NCBIm37
MGSCv36120,788,165 - 20,805,364 (-)NCBImm8
Celera120,676,980 - 20,695,949 (-)NCBICelera
Cytogenetic Map1A4NCBI
Mcm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2923,219,169 - 23,237,314 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl923,219,169 - 23,237,314 (-)Ensembl
Rnor_6.0926,914,057 - 26,932,201 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl926,914,057 - 26,932,201 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0925,770,288 - 25,788,432 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4919,536,922 - 19,554,871 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1919,534,642 - 19,552,122 (-)NCBI
Celera920,794,785 - 20,812,805 (-)NCBICelera
Cytogenetic Map9q13NCBI
Mcm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554115,814,041 - 5,832,796 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554115,800,800 - 5,832,713 (+)NCBIChiLan1.0ChiLan1.0
MCM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1653,084,657 - 53,105,403 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl653,085,231 - 53,105,344 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0651,816,615 - 51,837,404 (-)NCBIMhudiblu_PPA_v0panPan3
Mcm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494655,412,234 - 55,429,506 (-)NCBI
SpeTri2.0NW_0049364768,530,614 - 8,547,971 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl746,084,661 - 46,104,375 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1746,084,648 - 46,104,425 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2752,534,805 - 52,554,554 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11720,222,440 - 20,243,807 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1720,222,590 - 20,243,809 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604452,162,228 - 52,183,499 (-)NCBIVero_WHO_p1.0
Mcm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248553,806,273 - 3,825,143 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 6
Low 5 5 22 6 5 6 2 12 8 10 6
Below cutoff 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000003463   ⟹   ENSCAFP00000003211
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1219,924,732 - 19,945,605 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000067750   ⟹   ENSCAFP00000056600
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1219,926,689 - 19,945,511 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000092164   ⟹   ENSCAFP00000059094
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1219,920,210 - 19,945,511 (-)Ensembl
RefSeq Acc Id: XM_038492036   ⟹   XP_038347964
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11219,928,809 - 19,950,166 (-)NCBI
RefSeq Acc Id: XM_038554301   ⟹   XP_038410229
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01220,170,450 - 20,191,818 (-)NCBI
RefSeq Acc Id: XM_038618164   ⟹   XP_038474092
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01220,031,993 - 20,053,341 (-)NCBI
RefSeq Acc Id: XM_038683753   ⟹   XP_038539681
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01220,422,999 - 20,444,648 (-)NCBI
RefSeq Acc Id: XM_538960   ⟹   XP_538960
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11219,924,017 - 19,945,576 (-)NCBI
Dog10K_Boxer_Tasha1219,821,166 - 19,842,529 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038347964 (Get FASTA)   NCBI Sequence Viewer  
  XP_038410229 (Get FASTA)   NCBI Sequence Viewer  
  XP_038474092 (Get FASTA)   NCBI Sequence Viewer  
  XP_038539681 (Get FASTA)   NCBI Sequence Viewer  
  XP_538960 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_538960   ⟸   XM_538960
- UniProtKB: E2RF73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000056600   ⟸   ENSCAFT00000067750
RefSeq Acc Id: ENSCAFP00000003211   ⟸   ENSCAFT00000003463
RefSeq Acc Id: ENSCAFP00000059094   ⟸   ENSCAFT00000092164
RefSeq Acc Id: XP_038347964   ⟸   XM_038492036
RefSeq Acc Id: XP_038474092   ⟸   XM_038618164
RefSeq Acc Id: XP_038539681   ⟸   XM_038683753
RefSeq Acc Id: XP_038410229   ⟸   XM_038554301


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002196 Ensembl
NCBI Gene MCM3 ENTREZGENE
UniProt E2RF73 ENTREZGENE
VGNC ID VGNC:43082 ENTREZGENE