EVX1 (even-skipped homeobox 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: EVX1 (even-skipped homeobox 1) Canis lupus familiaris
Analyze
Symbol: EVX1
Name: even-skipped homeobox 1
RGD ID: 12342155
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN embryo development ending in birth or egg hatching (ortholog); interneuron migration (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN axon (inferred); neuronal cell body (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox even-skipped homolog protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11440,416,167 - 40,422,412 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1440,418,589 - 40,423,482 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,847,018 - 39,853,198 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01440,354,897 - 40,361,088 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1440,356,898 - 40,362,225 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11440,468,697 - 40,474,874 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01440,153,807 - 40,159,977 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,512,501 - 40,518,673 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (IEA)
neuronal cell body  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EVX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11440,416,167 - 40,422,412 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1440,418,589 - 40,423,482 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,847,018 - 39,853,198 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01440,354,897 - 40,361,088 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1440,356,898 - 40,362,225 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11440,468,697 - 40,474,874 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01440,153,807 - 40,159,977 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,512,501 - 40,518,673 (+)NCBIUU_Cfam_GSD_1.0
EVX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38727,242,802 - 27,247,830 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl727,242,700 - 27,250,493 (+)EnsemblGRCh38hg38GRCh38
GRCh37727,282,421 - 27,287,449 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36727,248,689 - 27,252,717 (+)NCBINCBI36Build 36hg18NCBI36
Build 34727,055,660 - 27,059,432NCBI
Celera727,271,101 - 27,275,129 (+)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef727,162,395 - 27,166,423 (+)NCBIHuRef
CHM1_1727,281,891 - 27,285,919 (+)NCBICHM1_1
T2T-CHM13v2.0727,378,788 - 27,383,816 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2727,333,351 - 27,337,379 (+)NCBI
Evx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,290,483 - 52,295,374 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,290,483 - 52,295,363 (+)EnsemblGRCm39 Ensembl
GRCm38652,313,498 - 52,318,389 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,313,498 - 52,318,378 (+)EnsemblGRCm38mm10GRCm38
MGSCv37652,263,492 - 52,268,372 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36652,243,076 - 52,247,956 (+)NCBIMGSCv36mm8
Celera652,834,900 - 52,839,780 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.44NCBI
Evx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8482,747,192 - 82,751,569 (+)NCBIGRCr8
mRatBN7.2481,416,590 - 81,420,967 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,416,590 - 81,420,967 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0482,370,829 - 82,374,313 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,370,997 - 82,375,374 (+)EnsemblRnor6.0rn6Rnor6.0
Celera476,305,676 - 76,309,160 (+)NCBICelera
Cytogenetic Map4q24NCBI
Evx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541028,939,416 - 28,942,751 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541028,939,416 - 28,942,751 (+)NCBIChiLan1.0ChiLan1.0
EVX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2632,071,961 - 32,076,982 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1780,396,685 - 80,401,706 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0727,887,145 - 27,892,267 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1727,486,329 - 27,491,245 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl727,486,329 - 27,491,245 (+)Ensemblpanpan1.1panPan2
Evx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511884,661,027 - 84,666,323 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364783,873,109 - 3,876,784 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364783,873,007 - 3,876,784 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EVX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1845,326,710 - 45,331,368 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11845,327,711 - 45,331,204 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21849,960,837 - 49,964,997 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EVX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,118,911 - 31,130,186 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2131,123,397 - 31,126,792 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604273,606,380 - 73,611,963 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Evx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247393,355,578 - 3,358,947 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247393,354,191 - 3,358,961 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EVX1
68 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5
Below cutoff 5 15 6 3 10 7 8 5

Sequence


RefSeq Acc Id: ENSCAFT00000004757   ⟹   ENSCAFP00000004404
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1440,418,589 - 40,423,482 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845028980   ⟹   ENSCAFP00845022799
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1440,356,898 - 40,362,225 (+)Ensembl
RefSeq Acc Id: XM_038495295   ⟹   XP_038351223
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11440,468,697 - 40,474,874 (+)NCBI
RefSeq Acc Id: XM_038556391   ⟹   XP_038412319
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01440,512,501 - 40,518,673 (+)NCBI
RefSeq Acc Id: XM_038620315   ⟹   XP_038476243
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01440,153,807 - 40,159,977 (+)NCBI
RefSeq Acc Id: XM_038685993   ⟹   XP_038541921
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01440,354,897 - 40,361,088 (+)NCBI
RefSeq Acc Id: XM_539493   ⟹   XP_539493
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11440,416,167 - 40,422,412 (+)NCBI
Dog10K_Boxer_Tasha1439,847,018 - 39,853,198 (+)NCBI
Sequence:
RefSeq Acc Id: XP_539493   ⟸   XM_539493
- UniProtKB: A0A8C0YTZ1 (UniProtKB/TrEMBL),   A0A8C0JR72 (UniProtKB/TrEMBL),   A0A8I3P7S7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000004404   ⟸   ENSCAFT00000004757
RefSeq Acc Id: XP_038351223   ⟸   XM_038495295
RefSeq Acc Id: XP_038476243   ⟸   XM_038620315
RefSeq Acc Id: XP_038541921   ⟸   XM_038685993
- UniProtKB: A0A8C0YTZ1 (UniProtKB/TrEMBL),   A0A8C0JR72 (UniProtKB/TrEMBL),   A0A8I3P7S7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038412319   ⟸   XM_038556391
- UniProtKB: A0A8C0JR72 (UniProtKB/TrEMBL),   A0A8C0YTZ1 (UniProtKB/TrEMBL),   A0A8I3P7S7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845022799   ⟸   ENSCAFT00845028980
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002971 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030005778 UniProtKB/TrEMBL
  ENSCAFG00040009987 UniProtKB/TrEMBL
  ENSCAFG00845016314 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000004757.6 UniProtKB/TrEMBL
  ENSCAFT00030010585.1 UniProtKB/TrEMBL
  ENSCAFT00040018531.1 UniProtKB/TrEMBL
  ENSCAFT00845028980 ENTREZGENE
  ENSCAFT00845028980.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/TrEMBL
KEGG Report cfa:482376 UniProtKB/TrEMBL
NCBI Gene EVX1 ENTREZGENE
PANTHER HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 1 UniProtKB/TrEMBL
  SEGMENTATION PROTEIN EVEN-SKIPPED UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
PRINTS HOMEOBOX UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A8C0JR72 ENTREZGENE
  A0A8C0YTZ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P7S7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40506 ENTREZGENE