CDK2AP2 (cyclin dependent kinase 2 associated protein 2) - Rat Genome Database

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Gene: CDK2AP2 (cyclin dependent kinase 2 associated protein 2) Canis lupus familiaris
Analyze
Symbol: CDK2AP2
Name: cyclin dependent kinase 2 associated protein 2 (Ensembl:phosphatidylinositol transfer protein membrane associated 1)
RGD ID: 12338292
Description: ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); phosphatidic acid binding (inferred); INVOLVED IN regulation of stem cell division (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN NuRD complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CDK2-associated protein 2; cyclin-dependent kinase 2-associated protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11849,969,630 - 49,971,781 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1849,970,160 - 49,971,457 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1848,580,124 - 48,582,321 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01850,892,011 - 50,894,208 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1850,892,068 - 50,908,430 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11850,105,317 - 50,107,514 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01849,679,848 - 49,682,045 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01850,474,088 - 50,476,285 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CDK2AP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11849,969,630 - 49,971,781 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1849,970,160 - 49,971,457 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1848,580,124 - 48,582,321 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01850,892,011 - 50,894,208 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1850,892,068 - 50,908,430 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11850,105,317 - 50,107,514 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01849,679,848 - 49,682,045 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01850,474,088 - 50,476,285 (+)NCBIUU_Cfam_GSD_1.0
CDK2AP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381167,506,497 - 67,508,162 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1167,506,497 - 67,508,649 (-)EnsemblGRCh38hg38GRCh38
GRCh371167,273,968 - 67,275,633 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,030,544 - 67,032,678 (-)NCBINCBI36Build 36hg18NCBI36
Celera1164,608,370 - 64,610,504 (-)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1163,603,170 - 63,605,408 (-)NCBIHuRef
CHM1_11167,157,015 - 67,159,253 (-)NCBICHM1_1
T2T-CHM13v2.01167,501,174 - 67,502,839 (-)NCBIT2T-CHM13v2.0
Cdk2ap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39194,146,204 - 4,149,019 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl194,147,182 - 4,149,019 (+)EnsemblGRCm39 Ensembl
GRCm38194,096,206 - 4,099,019 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl194,097,182 - 4,099,019 (+)EnsemblGRCm38mm10GRCm38
MGSCv37194,097,351 - 4,099,017 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,097,351 - 4,099,017 (+)NCBIMGSCv36mm8
Celera193,968,253 - 3,969,919 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.8NCBI
Cdk2ap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,819,155 - 210,822,604 (+)NCBIGRCr8
mRatBN7.21201,391,056 - 201,393,137 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1201,391,466 - 201,393,137 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1209,743,716 - 209,745,384 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01216,836,947 - 216,838,615 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01209,527,960 - 209,529,628 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,345,638 - 219,347,709 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,345,918 - 219,347,728 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,216,312 - 226,218,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,681,430 - 206,683,098 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1198,935,992 - 198,937,660 (+)NCBICelera
Cytogenetic Map1q43NCBI
Cdk2ap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542217,981,267 - 17,984,517 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542217,981,267 - 17,983,480 (+)NCBIChiLan1.0ChiLan1.0
CDK2AP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2968,734,077 - 68,736,325 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11169,776,660 - 69,778,908 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01162,865,554 - 62,867,756 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11166,176,917 - 66,179,154 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1166,176,917 - 66,179,154 (-)Ensemblpanpan1.1panPan2
Cdk2ap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049475,815,870 - 5,817,534 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365992,257,671 - 2,259,886 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365992,257,731 - 2,259,883 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK2AP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl25,025,600 - 5,027,764 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.125,025,256 - 5,027,766 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.223,743,767 - 3,746,277 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK2AP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116,756,853 - 6,759,087 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl16,756,909 - 6,759,090 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038104,034,694 - 104,036,928 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk2ap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476719,027,912 - 19,030,835 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476719,028,442 - 19,030,580 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CDK2AP2
8 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 2 12 4 10 6
Low 4 4
Below cutoff

Sequence


RefSeq Acc Id: ENSCAFT00000018065   ⟹   ENSCAFP00000016732
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1849,970,160 - 49,971,457 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845016878   ⟹   ENSCAFP00845013132
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1850,892,068 - 50,908,430 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017021   ⟹   ENSCAFP00845013260
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1850,892,068 - 50,908,430 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017143   ⟹   ENSCAFP00845013355
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1850,892,075 - 50,894,194 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017177   ⟹   ENSCAFP00845013385
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1850,895,347 - 50,908,425 (+)Ensembl
RefSeq Acc Id: XM_038424794   ⟹   XP_038280722
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01850,892,011 - 50,894,208 (+)NCBI
RefSeq Acc Id: XM_038501036   ⟹   XP_038356964
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11850,105,317 - 50,107,514 (+)NCBI
RefSeq Acc Id: XM_038563736   ⟹   XP_038419664
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01850,474,088 - 50,476,285 (+)NCBI
RefSeq Acc Id: XM_038627846   ⟹   XP_038483774
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01849,679,848 - 49,682,045 (+)NCBI
RefSeq Acc Id: XM_846714   ⟹   XP_851807
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11849,969,630 - 49,971,781 (+)NCBI
Dog10K_Boxer_Tasha1848,580,124 - 48,582,321 (+)NCBI
Sequence:
RefSeq Acc Id: XP_851807   ⟸   XM_846714
- UniProtKB: A0A8C0PGV6 (UniProtKB/TrEMBL),   A0A8C0JM25 (UniProtKB/TrEMBL),   A0A8I3ND43 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000016732   ⟸   ENSCAFT00000018065
RefSeq Acc Id: XP_038356964   ⟸   XM_038501036
RefSeq Acc Id: XP_038483774   ⟸   XM_038627846
RefSeq Acc Id: XP_038280722   ⟸   XM_038424794
- UniProtKB: A0A8C0PGV6 (UniProtKB/TrEMBL),   A0A8C0JM25 (UniProtKB/TrEMBL),   A0A8I3ND43 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038419664   ⟸   XM_038563736
- UniProtKB: A0A8C0JM25 (UniProtKB/TrEMBL),   A0A8C0PGV6 (UniProtKB/TrEMBL),   A0A8I3ND43 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845013355   ⟸   ENSCAFT00845017143
RefSeq Acc Id: ENSCAFP00845013132   ⟸   ENSCAFT00845016878
RefSeq Acc Id: ENSCAFP00845013260   ⟸   ENSCAFT00845017021
RefSeq Acc Id: ENSCAFP00845013385   ⟸   ENSCAFT00845017177
Protein Domains
DDHD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011370 Ensembl
  ENSCAFG00000011451 UniProtKB/TrEMBL
  ENSCAFG00030021776 UniProtKB/TrEMBL
  ENSCAFG00040010457 UniProtKB/TrEMBL
  ENSCAFG00845009575 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000018065.5 UniProtKB/TrEMBL
  ENSCAFT00030039932.1 UniProtKB/TrEMBL
  ENSCAFT00040019362.1 UniProtKB/TrEMBL
  ENSCAFT00845016878.1 UniProtKB/TrEMBL
  ENSCAFT00845017021.1 UniProtKB/TrEMBL
  ENSCAFT00845017143 ENTREZGENE
  ENSCAFT00845017143.1 UniProtKB/TrEMBL
  ENSCAFT00845017177.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.530.20 UniProtKB/TrEMBL
  6.10.140.1300 UniProtKB/TrEMBL
InterPro DDHD_dom UniProtKB/TrEMBL
  DOC_1/2 UniProtKB/TrEMBL
  HAD-like_sf UniProtKB/TrEMBL
  LNS2/PITP UniProtKB/TrEMBL
  PI_transfer UniProtKB/TrEMBL
  START-like_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:610458 UniProtKB/TrEMBL
NCBI Gene CDK2AP2 ENTREZGENE
PANTHER CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 2 UniProtKB/TrEMBL
  MEMBRANE-ASSOCIATED PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1 UniProtKB/TrEMBL
  PTHR10658 UniProtKB/TrEMBL
  PTHR22607 UniProtKB/TrEMBL
Pfam CDK2AP UniProtKB/TrEMBL
  DDHD UniProtKB/TrEMBL
  IP_trans UniProtKB/TrEMBL
PIRSF CDK2-associated_p2 UniProtKB/TrEMBL
PRINTS PITRANSFER UniProtKB/TrEMBL
PROSITE DDHD UniProtKB/TrEMBL
SMART DDHD UniProtKB/TrEMBL
  LNS2 UniProtKB/TrEMBL
Superfamily-SCOP Bet v1-like UniProtKB/TrEMBL
  SSF56784 UniProtKB/TrEMBL
UniProt A0A8C0JM25 ENTREZGENE
  A0A8C0PGV6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N343_CANLF UniProtKB/TrEMBL
  A0A8I3ND43 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RVF0_CANLF UniProtKB/TrEMBL
  A0A8I3RWZ9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:51861 ENTREZGENE