SLA2 (Src like adaptor 2) - Rat Genome Database

Name: SLA2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: SLA2 (Src like adaptor 2) Canis lupus familiaris

Analyze

Symbol:

SLA2

Name:

Src like adaptor 2

RGD ID:

12335191

Description:

ENCODES a protein that exhibits epidermal growth factor receptor binding (inferred); phosphotyrosine residue binding (inferred); signaling adaptor activity (inferred); INVOLVED IN T cell activation (ortholog); ASSOCIATED WITH focal epilepsy (ortholog); genetic disease (ortholog); FOUND IN COP9 signalosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

src-like-adapter 2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLA2 (Src like adaptor 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Sla2 (Src-like-adaptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Sla2 (Src-like-adaptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sla2 (Src like adaptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLA2 (Src like adaptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sla2 (Src like adaptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLA2 (Src like adaptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLA2 (Src like adaptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sla2 (Src like adaptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	25,396,187 - 25,426,789 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	25,396,900 - 25,422,467 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	25,039,425 - 25,072,052 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	26,091,095 - 26,123,942 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	26,094,518 - 26,120,342 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	25,369,896 - 25,402,347 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	25,468,792 - 25,501,560 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	25,959,331 - 25,992,034 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

focal epilepsy (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of calcium-mediated signaling (IEA)

negative regulation of T cell receptor signaling pathway (IEA)

negative regulation of transcription by RNA polymerase II (IEA)

regulation of MAPK cascade (IEA)

signal transduction (IEA)

T cell activation (IEA,ISO)

Cellular Component

COP9 signalosome (IEA)

cytoplasm (IEA)

cytoplasmic vesicle (IEA)

Golgi apparatus (IEA)

intracellular membrane-bounded organelle (IEA)

late endosome (IEA)

nucleoplasm (IEA)

plasma membrane (IEA)

Molecular Function

epidermal growth factor receptor binding (IEA)

phosphotyrosine residue binding (IEA)

protein binding (ISO)

signaling adaptor activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

SLA2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	25,396,187 - 25,426,789 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	25,396,900 - 25,422,467 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	25,039,425 - 25,072,052 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	26,091,095 - 26,123,942 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	26,094,518 - 26,120,342 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	25,369,896 - 25,402,347 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	25,468,792 - 25,501,560 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	25,959,331 - 25,992,034 (-)	NCBI		UU_Cfam_GSD_1.0

SLA2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	36,612,318 - 36,646,196 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	36,612,318 - 36,646,196 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	35,240,721 - 35,274,599 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	34,674,336 - 34,707,972 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	34,674,339 - 34,707,972	NCBI
Celera	20	31,947,996 - 31,982,111 (-)	NCBI		Celera
Cytogenetic Map	20	q11.23	NCBI
HuRef	20	31,976,969 - 32,010,653 (-)	NCBI		HuRef
CHM1_1	20	35,142,627 - 35,176,530 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	20	38,336,183 - 38,370,537 (-)	NCBI		T2T-CHM13v2.0

Sla2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	156,716,071 - 156,729,161 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	156,714,377 - 156,729,112 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	156,874,151 - 156,887,250 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	156,872,457 - 156,887,192 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	156,698,658 - 156,712,814 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	156,698,658 - 156,712,928 (-)	NCBI		MGSCv36	mm8
Celera	2	162,808,644 - 162,822,518 (-)	NCBI		Celera
Cytogenetic Map	2	H1	NCBI
cM Map	2	77.89	NCBI

Sla2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	165,821,164 - 165,848,087 (-)	NCBI		GRCr8
mRatBN7.2	3	145,367,070 - 145,383,586 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	145,368,598 - 145,382,480 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	149,234,054 - 149,247,445 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	157,850,772 - 157,864,130 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	155,589,831 - 155,603,360 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	152,942,838 - 153,004,047 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	152,944,452 - 153,001,309 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	158,742,486 - 158,752,778 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	147,277,668 - 147,290,729 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	144,085,665 - 144,098,964 (-)	NCBI		Celera
Cytogenetic Map	3	q42	NCBI

Sla2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	24,986,028 - 25,003,732 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	24,978,447 - 25,003,732 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLA2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	42,350,879 - 42,387,763 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	42,343,837 - 42,381,788 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	32,945,409 - 32,978,966 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	34,065,385 - 34,098,581 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	34,065,385 - 34,098,581 (-)	Ensembl	panpan1.1		panPan2

Sla2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	174,320,591 - 174,344,978 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936561	4,413,108 - 4,428,110 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936561	4,408,531 - 4,427,476 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLA2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	39,875,628 - 39,902,940 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	39,875,625 - 39,904,838 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SLA2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666054	655,122 - 689,911 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sla2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624842	2,853,144 - 2,881,116 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624842	2,853,183 - 2,882,269 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SLA2
245 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium					4
Low	5				2		4				5	1
Below cutoff		5	22	6		6	2	6	12	8	5	5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022409145	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038433717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038433718	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038433719	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038433720	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038457682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038457683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038572198	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038572199	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038572200	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038572201	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038636453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038636454	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038636455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038636456	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_542983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000265	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000013592 ⟹ ENSCAFP00000012577

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	24	25,396,900 - 25,422,467 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845046043 ⟹ ENSCAFP00845036149

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	24	26,094,518 - 26,120,342 (-)	Ensembl

RefSeq Acc Id:

XM_022409145 ⟹ XP_022264853

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	25,396,187 - 25,426,789 (-)	NCBI
Dog10K_Boxer_Tasha	24	25,039,425 - 25,072,045 (-)	NCBI

Sequence:

show sequence

TTCAATCCTGGGTCCCCAGGATCGCGCCCTGGGCCAAAGGCAGGCGCCAAACCGCTGCGCCACC
CAGGGATCCCAGAAATTTCTTTATCCTACCTGAGTGATTCTCCAGTTTGGGCTGTGCATCAGAA
CACCTGGAGGCTCGTGGAAAGCAATTGCTGGCCACACCTAGTTTCTGATCTAGTAGATCCGAGA
TGGGGCCCAAGAATTTGCCTAACAAACTCCCAGATGATGCTGAGGCTACTGGCCTGAGACCACA
CTTGGAGAACCACTATCCAGGTCTTGTTACTCAAAGTGCATGGACCAGCAATATGGGTATTGCC
TGGGTGTTATTAGCAATTCAGTCCTCAATCCCCACCCCAGACCCACCAAACTAGAACCTGCTAT
TTAACAAGATCCCTAAGGGATACCTATACACATTAAAGACTGGGACGCATCAATCCAAGGCTGT
GCTTCCCCCGAAACCAGTTAAGTGCATCTCTTGGAGTATATAAAGTTCAGATTCCTTGGCTTTC
CTCTGGTGACTTAAATTCAGAAAATGGAGGAGCAGCCCAGGAATCTGATACCAAAAGAACCTCA
GGTGATTATAATAGTCAGGTAAGCTTAGGAAACCCCTCATTTACCTCAGTTCTGTGTTCCTCAG
GCAAGACCAAGCCACAAAGCCAGAGAAAAAACTCTAGGATAATGACAAGGCAGCTGCTTCTCTT
TTAGAAACAGGAACTTGGGGAAGGTGGCTCCTTGATGGTCTGTGATGACGTCAGAGGAAATGGG
TGGTTGTGAGAACCACAGAACCTGCAGATGTGAGCCGGGAGCCCCAAGGACCCTATGACAGAGC
TCAAAGAACCCCAGGCATTCTTCCCTGGCCGTCTGTGCTTGGGAGGGCTGTCCAATGCCGGGGT
CCCTAAGGAGCACCAGTCTCCTGTCCCATTGCAGGTCTACAAACTGCTGACCACAACAGATGGC
AGAGCTACCCAAAGTGATACCAAGAGCATCTCCCTGAAGAGCCTTCCAGGCTGAGAGGATTCTG
GGTATCCTAGGACTAAGGACTTTGACAGATGTCCAGAAGGGCCGTCCAAAGCCCTAACCTCTCC
AGCCAAAGCATGCATCTAAGCTGAGCCCCTGCCCCAAGCTTTGATGACAGGAAACCAATTTCTC
TAGGCCATGTACTTCTGCGTGTTCTGCTGAGGAACAATGGGAGGTCAGCTCAGCCGAGGGAAAA
CCCTGCCAAGCCCAAGCTCGAGGCCCTCTGTCCAAGAACTGGACCCTGTGCCCATGCAAGCAGA
GAGAAGCAGGGCCACAGCCGTGGCCCTGAGCAGTTTCCCAGTAGGCGAGCACACAGAGCCATCA
CTGAGACTGGGGGATCCATTGACCATCACCTCTGAGTGGCTGTATGAAGGCCTGAGCCGGGAGA
AAGCTGAAGAACTGCTGTTGCTGCCTGGAAACCCTGGAGGGGCCTTCCTCATTCGGGAGAGCCA
GACCAGGACAGGGTGTTACTCCCTGTCAGTCCGCCTCAGCCGCCCTGCGTCGTGGGACAGGATC
AGACACTACAGGATCCAGCACCTTGATAACGGCTGGCTGTACATCTCACCACGCCTCACCTTCC
CTTCACTCCAGGCCCTAGTGGATCATTATTCTGAGTTGGCGGATGACATCTGCTGCCTCCTTAA
GGAACCCTGTGCCCTGCGGAGGGCTGGCCCACTCCCTGGCAAGTCCATACCCCTACCTGTTACT
GTGCAGAGGGCACCACTCAATTGGAAAGAGCTGGACAGCTCCCTCCTGTTTGCTGAAGCACCTG
CAGCAGGGGAGTCCCCTCTCCTCAGCGAGGGGCTCCGGGAGGCCCTCAGCTCCTACATCAGCCT
GACCGATGACAGCTCCTTGGAGGATGCCATGGCCCAAAGCAGAGGCCAAACGGGAATCCAACGC
TGCAGCACCTAGACCCCCAGCTCAGCTCAGCCTGAGTACTCCAGAGGCAAATTCAGAGTCCCAC
CTGTGTCCTCTGTTACTTCCTCTTAGCCCTAACAAGTCAATTAACCCTCTCCCAGTGCCATGAA
CCCACCTGCAACCTCTAGTTCAAATAAATGGACAGGGCTCCAAAGAGACTAAGCCTTTGGGGTT
TGACCCAGTTTGACCGGAGTTTAGGATTTCCAGTACCATCTTCCTCCCCTGCCTGATGATCCCC
TTCTATACTCCTACAACCCCACCCACTAGGTAGAAACAACCACTAGCATCAAGAAAAAAAAATC
ATTTGAAGAGAATTTACCATTCTCAAAAGGCAGGACCGTGGCCCAGAAGGGACAGGAAAGCAGA
AGGGATGGATGTCTTACCACAGCAACAGAACCCAGGATGTCCAGCCTCCACCTGGTTCCCAGAG
GAAAGGGGACCTCTCACAGTCCAGGTTCTCAAACAGCCCCACCAAACCTCTTCTCTGAACAGTC
CTAGCTTCAAGATCTCTTTCATTTTGTGGCTTATCATTTGAACCTGCCTAAACTTTCCAGTCTA
CAGTGGCCTTGCCATCTTGTAGTCAAACACAAAATGGCAACTTCTGGGCCTGGCACACTACGGT
GAGGTCGGTCATGTGTCTCAGTGTTGGGCAGGGGCATCAGACGTCAGTAAGCCTCTCTCCACAA
AGCCAAGACCACAGCCTACAC

hide sequence

RefSeq Acc Id:

XM_038433717 ⟹ XP_038289645

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	26,091,095 - 26,123,917 (-)	NCBI

RefSeq Acc Id:

XM_038433718 ⟹ XP_038289646

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	26,091,095 - 26,123,934 (-)	NCBI

RefSeq Acc Id:

XM_038433719 ⟹ XP_038289647

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	26,091,095 - 26,123,942 (-)	NCBI

RefSeq Acc Id:

XM_038433720 ⟹ XP_038289648

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	26,094,478 - 26,123,940 (-)	NCBI

RefSeq Acc Id:

XM_038457682 ⟹ XP_038313610

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	24	25,039,425 - 25,072,052 (-)	NCBI

RefSeq Acc Id:

XM_038457683 ⟹ XP_038313611

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	24	25,042,808 - 25,072,050 (-)	NCBI

RefSeq Acc Id:

XM_038508863 ⟹ XP_038364791

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	25,369,896 - 25,402,322 (-)	NCBI

RefSeq Acc Id:

XM_038508864 ⟹ XP_038364792

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	25,369,896 - 25,402,340 (-)	NCBI

RefSeq Acc Id:

XM_038508865 ⟹ XP_038364793

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	25,369,896 - 25,402,347 (-)	NCBI

RefSeq Acc Id:

XM_038508866 ⟹ XP_038364794

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	25,373,279 - 25,402,345 (-)	NCBI

RefSeq Acc Id:

XM_038572198 ⟹ XP_038428126

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	25,959,331 - 25,992,009 (-)	NCBI

RefSeq Acc Id:

XM_038572199 ⟹ XP_038428127

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	25,959,331 - 25,992,026 (-)	NCBI

RefSeq Acc Id:

XM_038572200 ⟹ XP_038428128

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	25,959,331 - 25,992,034 (-)	NCBI

RefSeq Acc Id:

XM_038572201 ⟹ XP_038428129

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	25,962,712 - 25,992,032 (-)	NCBI

RefSeq Acc Id:

XM_038636453 ⟹ XP_038492381

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	25,468,792 - 25,501,535 (-)	NCBI

RefSeq Acc Id:

XM_038636454 ⟹ XP_038492382

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	25,468,792 - 25,501,553 (-)	NCBI

RefSeq Acc Id:

XM_038636455 ⟹ XP_038492383

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	25,468,792 - 25,501,560 (-)	NCBI

RefSeq Acc Id:

XM_038636456 ⟹ XP_038492384

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	25,472,175 - 25,501,559 (-)	NCBI

RefSeq Acc Id:

XM_542983 ⟹ XP_542983

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	25,396,187 - 25,426,789 (-)	NCBI
Dog10K_Boxer_Tasha	24	25,039,425 - 25,072,027 (-)	NCBI

Sequence:

show sequence

TTCAATCCTGGGTCCCCAGGATCGCGCCCTGGGCCAAAGGCAGGCGCCAAACCGCTGCGCCACC
CAGGGATCCCAGAAATTTCTTTATCCTACCTGAGTGATTCTCCAGTTTGGGCTGTGCATCAGAA
CACCTGGAGGCTCGTGGAAAGCAATTGCTGGCCACACCTAGTTTCTGATCTAGTAGATCCGAGA
TGGGGCCCAAGAATTTGCCTAACAAACTCCCAGATGATGCTGAGGCTACTGGCCTGAGACCACA
CTTGGAGAACCACTATCCAGGTCTTGTTACTCAAAGTGCATGGACCAGCAATATGGGTATTGCC
TGGGTGTTATTAGCAATTCAGTCCTCAATCCCCACCCCAGACCCACCAAACTAGAACCTGCTAT
TTAACAAGATCCCTAAGGGATACCTATACACATTAAAGACTGGGACGCATCAATCCAAGGCTGT
GCTTCCCCCGAAACCAGTTAAGTGCATCTCTTGGAGTATATAAAGTTCAGATTCCTTGGCTTTC
CTCTGGTGACTTAAATTCAGAAAATGGAGGAGCAGCCCAGGAATCTGATACCAAAAGAACCTCA
GGTGATTATAATAGTCAGGTAAGCTTAGGAAACCCCTCATTTACCTCAGTTCTGTGTTCCTCAG
GCAAGACCAAGCCACAAAGCCAGAGAAAAAACTCTAGGATAATGACAAGGCAGCTGCTTCTCTT
TTAGAAACAGGAACTTGGGGAAGGTGGCTCCTTGATGGTCTGTGATGACGTCAGAGGAAATGGG
TGGTTGTGAGAACCACAGAACCTGCAGATGTGAGCCGGGAGCCCCAAGGACCCTATGACAGAGC
TCAAAGAACCCCAGGCATTCTTCCCTGGCCGTCTGTGCTTGGGAGGGCTGTCCAATGCCGGGGT
CCCTAAGGAGCACCAGTCTCCTGTCCCATTGCAGGTCTACAAACTGCTGACCACAACAGATGGC
AGAGCTACCCAAAGTGATACCAAGAGCATCTCCCTGAAGAGCCTTCCAGGCTGAGAGGATTCTG
GGTATCCTAGGACTAAGGACTTTGACAGATGTCCAGAAGGGCCGTCCAAAGCCCTAACCTCTCC
AGCCAAAGCATGCATCTAAGCTGAGCCCCTGCCCCAAGCTTTGATGACAGGAAACCAATTTCTC
TAGGCCATGTACTTCTGCGTGTTCTGCTGAGGAACAATGGGAGGTCAGCTCAGCCGAGGGAAAA
CCCTGCCAAGCCCAAGCTCGAGGCCCTCTGTCCAAGAACTGGACCCTGTGCCCATGCAAGCAGA
GAGAAGCAGGGCCACAGCCGTGGCCCTGAGCAGTTTCCCAGTAGGCGAGCACACAGAGCCATCA
CTGAGACTGGGGGATCCATTGACCATCACCTCTGAAGATGGAGACTGGTGGACAGTGATATCAG
AAGTTTCAGGCACAGAATACAGCATCCCCAGCAGCCACGTGGCCAAAATCTCCCATGGGTGGCT
GTATGAAGGCCTGAGCCGGGAGAAAGCTGAAGAACTGCTGTTGCTGCCTGGAAACCCTGGAGGG
GCCTTCCTCATTCGGGAGAGCCAGACCAGGACAGGGTGTTACTCCCTGTCAGTCCGCCTCAGCC
GCCCTGCGTCGTGGGACAGGATCAGACACTACAGGATCCAGCACCTTGATAACGGCTGGCTGTA
CATCTCACCACGCCTCACCTTCCCTTCACTCCAGGCCCTAGTGGATCATTATTCTGAGTTGGCG
GATGACATCTGCTGCCTCCTTAAGGAACCCTGTGCCCTGCGGAGGGCTGGCCCACTCCCTGGCA
AGTCCATACCCCTACCTGTTACTGTGCAGAGGGCACCACTCAATTGGAAAGAGCTGGACAGCTC
CCTCCTGTTTGCTGAAGCACCTGCAGCAGGGGAGTCCCCTCTCCTCAGCGAGGGGCTCCGGGAG
GCCCTCAGCTCCTACATCAGCCTGACCGATGACAGCTCCTTGGAGGATGCCATGGCCCAAAGCA
GAGGCCAAACGGGAATCCAACGCTGCAGCACCTAGACCCCCAGCTCAGCTCAGCCTGAGTACTC
CAGAGGCAAATTCAGAGTCCCACCTGTGTCCTCTGTTACTTCCTCTTAGCCCTAACAAGTCAAT
TAACCCTCTCCCAGTGCCATGAACCCACCTGCAACCTCTAGTTCAAATAAATGGACAGGGCTCC
AAAGAGACTAAGCCTTTGGGGTTTGACCCAGTTTGACCGGAGTTTAGGATTTCCAGTACCATCT
TCCTCCCCTGCCTGATGATCCCCTTCTATACTCCTACAACCCCACCCACTAGGTAGAAACAACC
ACTAGCATCAAGAAAAAAAAATCATTTGAAGAGAATTTACCATTCTCAAAAGGCAGGACCGTGG
CCCAGAAGGGACAGGAAAGCAGAAGGGATGGATGTCTTACCACAGCAACAGAACCCAGGATGTC
CAGCCTCCACCTGGTTCCCAGAGGAAAGGGGACCTCTCACAGTCCAGGTTCTCAAACAGCCCCA
CCAAACCTCTTCTCTGAACAGTCCTAGCTTCAAGATCTCTTTCATTTTGTGGCTTATCATTTGA
ACCTGCCTAAACTTTCCAGTCTACAGTGGCCTTGCCATCTTGTAGTCAAACACAAAATGGCAAC
TTCTGGGCCTGGCACACTACGGTGAGGTCGGTCATGTGTCTCAGTGTTGGGCAGGGGCATCAGA
CGTCAGTAAGCCTCTCTCCACAAAGCCAAGACCACAGCCTACAC

hide sequence

Protein Sequences


Protein RefSeqs	XP_022264853	(Get FASTA)	NCBI Sequence Viewer
	XP_038289645	(Get FASTA)	NCBI Sequence Viewer
	XP_038289646	(Get FASTA)	NCBI Sequence Viewer
	XP_038289647	(Get FASTA)	NCBI Sequence Viewer
	XP_038289648	(Get FASTA)	NCBI Sequence Viewer
	XP_038313610	(Get FASTA)	NCBI Sequence Viewer
	XP_038313611	(Get FASTA)	NCBI Sequence Viewer
	XP_038364791	(Get FASTA)	NCBI Sequence Viewer
	XP_038364792	(Get FASTA)	NCBI Sequence Viewer
	XP_038364793	(Get FASTA)	NCBI Sequence Viewer
	XP_038364794	(Get FASTA)	NCBI Sequence Viewer
	XP_038428126	(Get FASTA)	NCBI Sequence Viewer
	XP_038428127	(Get FASTA)	NCBI Sequence Viewer
	XP_038428128	(Get FASTA)	NCBI Sequence Viewer
	XP_038428129	(Get FASTA)	NCBI Sequence Viewer
	XP_038492381	(Get FASTA)	NCBI Sequence Viewer
	XP_038492382	(Get FASTA)	NCBI Sequence Viewer
	XP_038492383	(Get FASTA)	NCBI Sequence Viewer
	XP_038492384	(Get FASTA)	NCBI Sequence Viewer
	XP_542983	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000012577.4
	ENSCAFP00000069842.1
	ENSCAFP00030040177.1
	ENSCAFP00040019265.1
	ENSCAFP00845036149
	ENSCAFP00845036149.1

RefSeq Acc Id:	XP_542983 ⟸ XM_542983
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SCF1 (UniProtKB/TrEMBL), A0A8C0JY00 (UniProtKB/TrEMBL), A0A8I3PN00 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGGQLSRGKTLPSPSSRPSVQELDPVPMQAERSRATAVALSSFPVGEHTEPSLRLGDPLTITSE DGDWWTVISEVSGTEYSIPSSHVAKISHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRTG CYSLSVRLSRPASWDRIRHYRIQHLDNGWLYISPRLTFPSLQALVDHYSELADDICCLLKEPCA LRRAGPLPGKSIPLPVTVQRAPLNWKELDSSLLFAEAPAAGESPLLSEGLREALSSYISLTDDS SLEDAMAQSRGQTGIQRCST hide sequence

RefSeq Acc Id:	XP_022264853 ⟸ XM_022409145
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3PN00 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGGQLSRGKTLPSPSSRPSVQELDPVPMQAERSRATAVALSSFPVGEHTEPSLRLGDPLTITSE WLYEGLSREKAEELLLLPGNPGGAFLIRESQTRTGCYSLSVRLSRPASWDRIRHYRIQHLDNGW LYISPRLTFPSLQALVDHYSELADDICCLLKEPCALRRAGPLPGKSIPLPVTVQRAPLNWKELD SSLLFAEAPAAGESPLLSEGLREALSSYISLTDDSSLEDAMAQSRGQTGIQRCST hide sequence

RefSeq Acc Id:

ENSCAFP00000012577 ⟸ ENSCAFT00000013592

RefSeq Acc Id:	XP_038364793 ⟸ XM_038508865
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038364792 ⟸ XM_038508864
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038364791 ⟸ XM_038508863
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038364794 ⟸ XM_038508866
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038492383 ⟸ XM_038636455
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038492382 ⟸ XM_038636454
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038492381 ⟸ XM_038636453
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038492384 ⟸ XM_038636456
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038289647 ⟸ XM_038433719
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3PN00 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038289646 ⟸ XM_038433718
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3PN00 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038289645 ⟸ XM_038433717
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SCF1 (UniProtKB/TrEMBL), A0A8C0JY00 (UniProtKB/TrEMBL), A0A8I3PN00 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038289648 ⟸ XM_038433720
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038313610 ⟸ XM_038457682
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3PN00 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038313611 ⟸ XM_038457683
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038428128 ⟸ XM_038572200
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3PN00 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038428127 ⟸ XM_038572199
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3PN00 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038428126 ⟸ XM_038572198
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JY00 (UniProtKB/TrEMBL), A0A8C0SCF1 (UniProtKB/TrEMBL), A0A8I3PN00 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038428129 ⟸ XM_038572201
- Peptide Label:	isoform X4

RefSeq Acc Id:

ENSCAFP00845036149 ⟸ ENSCAFT00845046043

Protein Domains

SH2 SH3

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000008573	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030024927	UniProtKB/TrEMBL
	ENSCAFG00040012027	UniProtKB/TrEMBL
	ENSCAFG00845026095	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000013592.4	UniProtKB/TrEMBL
	ENSCAFT00000102113.1	UniProtKB/TrEMBL
	ENSCAFT00030045987.1	UniProtKB/TrEMBL
	ENSCAFT00040022210.1	UniProtKB/TrEMBL
	ENSCAFT00845046043	ENTREZGENE
	ENSCAFT00845046043.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.505.10	UniProtKB/TrEMBL
	SH3 Domains	UniProtKB/TrEMBL
InterPro	Grb2-like	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	SH2_dom_sf	UniProtKB/TrEMBL
	SH3-like_dom_sf	UniProtKB/TrEMBL
	SH3_domain	UniProtKB/TrEMBL
NCBI Gene	SLA2	ENTREZGENE
PANTHER	PROTEIN ENHANCER OF SEVENLESS 2B	UniProtKB/TrEMBL
	SRC-LIKE-ADAPTOR 2	UniProtKB/TrEMBL
Pfam	SH2	UniProtKB/TrEMBL
PRINTS	SH2DOMAIN	UniProtKB/TrEMBL
PROSITE	SH2	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
SMART	SH2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50044	UniProtKB/TrEMBL
	SSF55550	UniProtKB/TrEMBL
UniProt	A0A8C0JY00	ENTREZGENE
	A0A8C0SCF1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PN00	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SDL6_CANLF	UniProtKB/TrEMBL
	A0A8P0TM15_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:46203	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar