MAT2B (methionine adenosyltransferase 2B) - Rat Genome Database

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Gene: MAT2B (methionine adenosyltransferase 2B) Canis lupus familiaris
Analyze
Symbol: MAT2B
Name: methionine adenosyltransferase 2B
RGD ID: 12333589
Description: ENCODES a protein that exhibits enzyme binding (inferred); INVOLVED IN one-carbon metabolic process (inferred); regulation of catalytic activity (inferred); S-adenosylmethionine biosynthetic process (inferred); PARTICIPATES IN choline metabolic pathway; glycine N-methyltransferase deficiency pathway; homocystinuria pathway; FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: methionine adenosyltransferase 2 subunit beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1447,703,991 - 47,726,363 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl447,709,576 - 47,726,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha447,597,100 - 47,621,728 (-)NCBI
ROS_Cfam_1.0448,134,581 - 48,159,235 (-)NCBI
UMICH_Zoey_3.1447,918,036 - 47,942,655 (-)NCBI
UNSW_CanFamBas_1.0448,076,525 - 48,101,129 (-)NCBI
UU_Cfam_GSD_1.0448,596,150 - 48,620,797 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
MAT2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1447,703,991 - 47,726,363 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl447,709,576 - 47,726,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha447,597,100 - 47,621,728 (-)NCBI
ROS_Cfam_1.0448,134,581 - 48,159,235 (-)NCBI
UMICH_Zoey_3.1447,918,036 - 47,942,655 (-)NCBI
UNSW_CanFamBas_1.0448,076,525 - 48,101,129 (-)NCBI
UU_Cfam_GSD_1.0448,596,150 - 48,620,797 (-)NCBI
MAT2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5163,503,114 - 163,519,354 (+)EnsemblGRCh38hg38GRCh38
GRCh385163,503,064 - 163,519,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375162,930,070 - 162,946,360 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365162,862,809 - 162,878,906 (+)NCBINCBI36hg18NCBI36
Celera5158,964,332 - 158,980,423 (+)NCBI
Cytogenetic Map5q34NCBI
HuRef5158,029,749 - 158,046,037 (+)NCBIHuRef
CHM1_15162,362,532 - 162,378,812 (+)NCBICHM1_1
Mat2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391140,570,141 - 40,586,030 (-)NCBIGRCm39mm39
GRCm39 Ensembl1140,570,141 - 40,586,030 (-)Ensembl
GRCm381140,679,314 - 40,695,203 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1140,679,314 - 40,695,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv371140,492,816 - 40,506,115 (-)NCBIGRCm37mm9NCBIm37
MGSCv361140,522,737 - 40,536,036 (-)NCBImm8
Celera1144,529,462 - 44,542,765 (-)NCBICelera
Cytogenetic Map11A5NCBI
Mat2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21025,106,928 - 25,122,982 (-)NCBI
Rnor_6.0 Ensembl1025,832,072 - 25,847,994 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01025,832,096 - 25,848,045 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01025,686,294 - 25,701,795 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41025,713,132 - 25,718,879 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1024,666,794 - 24,680,351 (-)NCBICelera
Cytogenetic Map10q12NCBI
Mat2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540816,910,414 - 16,924,663 (+)NCBIChiLan1.0ChiLan1.0
MAT2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15165,656,086 - 165,672,176 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5165,656,086 - 165,672,176 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05158,879,425 - 158,895,690 (+)NCBIMhudiblu_PPA_v0panPan3
Mat2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213102,094,901 - 102,111,644 (-)NCBI
SpeTri2.0NW_004936515544,218 - 561,014 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAT2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1660,255,357 - 60,274,085 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11660,255,541 - 60,274,228 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21665,065,436 - 65,111,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103244929
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12365,776,808 - 65,792,871 (+)NCBI
ChlSab1.1 Ensembl2365,779,437 - 65,792,369 (+)Ensembl
Vero_WHO_p1.0NW_023666097990,267 - 1,006,307 (-)NCBI
Mat2b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473326,296,920 - 26,309,228 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 17 1 6 1 6 1 12 8 10 6
Low 5 5 5 5 5
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003434508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022417726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_536439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000027206   ⟹   ENSCAFP00000025303
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl447,709,576 - 47,723,812 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000086322   ⟹   ENSCAFP00000062523
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl447,709,576 - 47,726,360 (-)Ensembl
RefSeq Acc Id: XM_003434508   ⟹   XP_003434556
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1447,706,542 - 47,723,861 (-)NCBI
Dog10K_Boxer_Tasha447,602,129 - 47,617,038 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022417726   ⟹   XP_022273434
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1447,703,991 - 47,723,861 (-)NCBI
Dog10K_Boxer_Tasha447,597,100 - 47,617,039 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038473747   ⟹   XP_038329675
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1447,923,063 - 47,937,964 (-)NCBI
RefSeq Acc Id: XM_038473748   ⟹   XP_038329676
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1447,923,063 - 47,940,348 (-)NCBI
RefSeq Acc Id: XM_038473749   ⟹   XP_038329677
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1447,923,063 - 47,942,655 (-)NCBI
RefSeq Acc Id: XM_038473750   ⟹   XP_038329678
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1447,918,036 - 47,937,965 (-)NCBI
RefSeq Acc Id: XM_038473751   ⟹   XP_038329679
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1447,923,063 - 47,937,964 (-)NCBI
RefSeq Acc Id: XM_038495850   ⟹   XP_038351778
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha447,602,129 - 47,621,728 (-)NCBI
RefSeq Acc Id: XM_038495867   ⟹   XP_038351795
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha447,602,129 - 47,617,038 (-)NCBI
RefSeq Acc Id: XM_038534827   ⟹   XP_038390755
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0448,601,176 - 48,616,094 (-)NCBI
RefSeq Acc Id: XM_038534828   ⟹   XP_038390756
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0448,601,176 - 48,618,490 (-)NCBI
RefSeq Acc Id: XM_038534829   ⟹   XP_038390757
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0448,601,176 - 48,620,797 (-)NCBI
RefSeq Acc Id: XM_038534830   ⟹   XP_038390758
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0448,596,150 - 48,616,096 (-)NCBI
RefSeq Acc Id: XM_038534831   ⟹   XP_038390759
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0448,601,176 - 48,616,095 (-)NCBI
RefSeq Acc Id: XM_038599127   ⟹   XP_038455055
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0448,081,551 - 48,096,444 (-)NCBI
RefSeq Acc Id: XM_038599128   ⟹   XP_038455056
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0448,081,551 - 48,098,819 (-)NCBI
RefSeq Acc Id: XM_038599129   ⟹   XP_038455057
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0448,081,551 - 48,101,129 (-)NCBI
RefSeq Acc Id: XM_038599131   ⟹   XP_038455059
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0448,076,525 - 48,096,446 (-)NCBI
RefSeq Acc Id: XM_038599132   ⟹   XP_038455060
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0448,081,551 - 48,096,445 (-)NCBI
RefSeq Acc Id: XM_038663433   ⟹   XP_038519361
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0448,139,608 - 48,154,527 (-)NCBI
RefSeq Acc Id: XM_038663434   ⟹   XP_038519362
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0448,139,608 - 48,156,922 (-)NCBI
RefSeq Acc Id: XM_038663435   ⟹   XP_038519363
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0448,139,608 - 48,159,235 (-)NCBI
RefSeq Acc Id: XM_038663436   ⟹   XP_038519364
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0448,134,581 - 48,154,529 (-)NCBI
RefSeq Acc Id: XM_038663437   ⟹   XP_038519365
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0448,139,608 - 48,154,528 (-)NCBI
RefSeq Acc Id: XM_536439   ⟹   XP_536439
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1447,708,989 - 47,726,363 (-)NCBI
Dog10K_Boxer_Tasha447,602,129 - 47,619,416 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_536439   ⟸   XM_536439
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003434556   ⟸   XM_003434508
- Peptide Label: isoform X1
- UniProtKB: E2RT47 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022273434   ⟸   XM_022417726
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCAFP00000025303   ⟸   ENSCAFT00000027206
RefSeq Acc Id: ENSCAFP00000062523   ⟸   ENSCAFT00000086322
RefSeq Acc Id: XP_038329678   ⟸   XM_038473750
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038329677   ⟸   XM_038473749
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038329676   ⟸   XM_038473748
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038329679   ⟸   XM_038473751
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038329675   ⟸   XM_038473747
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038455059   ⟸   XM_038599131
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038455057   ⟸   XM_038599129
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038455056   ⟸   XM_038599128
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038455060   ⟸   XM_038599132
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038455055   ⟸   XM_038599127
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038519364   ⟸   XM_038663436
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038519363   ⟸   XM_038663435
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038519362   ⟸   XM_038663434
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038519365   ⟸   XM_038663437
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038519361   ⟸   XM_038663433
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038351778   ⟸   XM_038495850
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038351795   ⟸   XM_038495867
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038390758   ⟸   XM_038534830
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038390757   ⟸   XM_038534829
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038390756   ⟸   XM_038534828
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038390759   ⟸   XM_038534831
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038390755   ⟸   XM_038534827
- Peptide Label: isoform X1
Protein Domains
RmlD_sub_bind

Promoters
RGD ID:13682994
Promoter ID:EPDNEW_C1062
Type:initiation region
Name:MAT2B_1
Description:methionine adenosyltransferase 2B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1447,723,831 - 47,723,891EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017181 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000025303 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000062523 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027206 UniProtKB/TrEMBL
  ENSCAFT00000086322 UniProtKB/TrEMBL
InterPro dTDP_dehydrorham_reduct UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  RmlD-like-bd UniProtKB/TrEMBL
KEGG Report cfa:479301 UniProtKB/TrEMBL
NCBI Gene MAT2B ENTREZGENE
PANTHER PTHR10491 UniProtKB/TrEMBL
Pfam RmlD_sub_bind UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A5F4D7V6_CANLF UniProtKB/TrEMBL
  E2RT47 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43038 ENTREZGENE