GALK1 (galactokinase 1) - Rat Genome Database

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Gene: GALK1 (galactokinase 1) Canis lupus familiaris
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Symbol: GALK1
Name: galactokinase 1
RGD ID: 12332974
Description: ENCODES a protein that exhibits ATP binding (ortholog); galactokinase activity (ortholog); galactose binding (ortholog); INVOLVED IN carbohydrate phosphorylation (ortholog); galactitol metabolic process (ortholog); galactose metabolic process (ortholog); PARTICIPATES IN galactokinase deficiency pathway; galactose metabolic pathway; galactosemia pathway; ASSOCIATED WITH cataract (ortholog); COVID-19 (ortholog); epidermolysis bullosa simplex localized type (ortholog); FOUND IN cytoplasm (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: galactokinase; galactose kinase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,818,558 - 4,824,845 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,805,650 - 4,833,503 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,498,590 - 5,504,867 (+)NCBI
ROS_Cfam_1.095,488,855 - 5,495,207 (+)NCBI
UMICH_Zoey_3.195,528,367 - 5,534,647 (+)NCBI
UNSW_CanFamBas_1.095,638,418 - 5,644,788 (+)NCBI
UU_Cfam_GSD_1.095,699,320 - 5,705,604 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISS)
cytosol  (IBA)
membrane  (ISS)
nucleosome  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:12620391   PMID:15932415  


Genomics

Comparative Map Data
GALK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,818,558 - 4,824,845 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,805,650 - 4,833,503 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,498,590 - 5,504,867 (+)NCBI
ROS_Cfam_1.095,488,855 - 5,495,207 (+)NCBI
UMICH_Zoey_3.195,528,367 - 5,534,647 (+)NCBI
UNSW_CanFamBas_1.095,638,418 - 5,644,788 (+)NCBI
UU_Cfam_GSD_1.095,699,320 - 5,705,604 (+)NCBI
GALK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1775,751,594 - 75,765,236 (-)EnsemblGRCh38hg38GRCh38
GRCh381775,751,469 - 75,765,192 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371773,747,550 - 73,761,273 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,265,613 - 71,272,875 (-)NCBINCBI36hg18NCBI36
Build 341771,265,612 - 71,272,875NCBI
Celera1770,344,064 - 70,351,327 (-)NCBI
Cytogenetic Map17q25.1NCBI
HuRef1769,178,882 - 69,186,794 (-)NCBIHuRef
CHM1_11773,819,092 - 73,826,355 (-)NCBICHM1_1
Galk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,899,183 - 115,903,545 (-)NCBIGRCm39mm39
GRCm39 Ensembl11115,899,283 - 115,903,545 (-)Ensembl
GRCm3811116,008,357 - 116,012,719 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,008,457 - 116,012,719 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711115,869,671 - 115,874,033 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611115,824,616 - 115,828,768 (-)NCBImm8
Celera11127,770,557 - 127,774,921 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.91NCBI
Galk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.210101,243,146 - 101,247,323 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl10101,235,994 - 101,247,337 (-)Ensembl
Rnor_6.010104,560,322 - 104,564,499 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10104,560,303 - 104,564,480 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010103,720,860 - 103,725,037 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,116,774 - 106,120,951 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110106,131,278 - 106,135,455 (-)NCBI
Celera1099,817,279 - 99,821,456 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Galk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,489,800 - 6,493,354 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,489,799 - 6,493,354 (+)NCBIChiLan1.0ChiLan1.0
GALK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11775,259,522 - 75,266,578 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,259,522 - 75,269,048 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01769,708,641 - 69,715,942 (-)NCBIMhudiblu_PPA_v0panPan3
Galk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,462,160 - 5,467,023 (+)NCBI
SpeTri2.0NW_004936594944,936 - 950,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GALK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,642,007 - 5,651,183 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,642,012 - 5,651,186 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,588,391 - 5,597,565 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GALK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,919,316 - 45,926,423 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,919,402 - 45,926,304 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607716,676,036 - 16,683,632 (+)NCBIVero_WHO_p1.0
Galk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248015,646,112 - 5,649,822 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000007903   ⟹   ENSCAFP00000007327
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,818,559 - 4,824,836 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000038442   ⟹   ENSCAFP00000034160
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,805,694 - 4,807,246 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000065230   ⟹   ENSCAFP00000045277
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,805,650 - 4,824,836 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000077921   ⟹   ENSCAFP00000047786
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,805,650 - 4,833,503 (+)Ensembl
RefSeq Acc Id: NM_001003104   ⟹   NP_001003104
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.194,818,559 - 4,824,837 (+)NCBI
Dog10K_Boxer_Tasha95,498,590 - 5,504,867 (+)NCBI
ROS_Cfam_1.095,488,890 - 5,495,199 (+)NCBI
UMICH_Zoey_3.195,528,367 - 5,534,647 (+)NCBI
UNSW_CanFamBas_1.095,638,418 - 5,644,788 (+)NCBI
UU_Cfam_GSD_1.095,699,320 - 5,705,604 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038674952   ⟹   XP_038530880
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.095,488,855 - 5,495,207 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001003104 (Get FASTA)   NCBI Sequence Viewer  
  XP_038530880 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG43832 (Get FASTA)   NCBI Sequence Viewer  
  AAO15527 (Get FASTA)   NCBI Sequence Viewer  
  AAP31026 (Get FASTA)   NCBI Sequence Viewer  
  Q9GKK4 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001003104   ⟸   NM_001003104
- UniProtKB: Q9GKK4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSCAFP00000047786   ⟸   ENSCAFT00000077921
RefSeq Acc Id: ENSCAFP00000034160   ⟸   ENSCAFT00000038442
RefSeq Acc Id: ENSCAFP00000007327   ⟸   ENSCAFT00000007903
RefSeq Acc Id: ENSCAFP00000045277   ⟸   ENSCAFT00000065230
RefSeq Acc Id: XP_038530880   ⟸   XM_038674952
- Peptide Label: isoform X1
Protein Domains
GHMP_kinases_C   GHMP_kinases_N   Histone

Promoters
RGD ID:13684419
Promoter ID:EPDNEW_C2489
Type:single initiation site
Name:GALK1_1
Description:galactokinase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.194,818,562 - 4,818,622EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004914 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00030004437 UniProtKB/Swiss-Prot
Ensembl Protein ENSCAFP00000007327 UniProtKB/Swiss-Prot
  ENSCAFP00000045277 UniProtKB/TrEMBL
  ENSCAFP00000047786 UniProtKB/TrEMBL
  ENSCAFP00030007172 UniProtKB/Swiss-Prot
Ensembl Transcript ENSCAFT00000007903 UniProtKB/Swiss-Prot
  ENSCAFT00000065230 UniProtKB/TrEMBL
  ENSCAFT00000077921 UniProtKB/TrEMBL
  ENSCAFT00030008166 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
  3.30.230.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.890 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Galactokinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Galactokinase_CS UniProtKB/Swiss-Prot
  GalKase_N UniProtKB/Swiss-Prot
  GHMP_kinase_C_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GHMP_kinase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GHMP_kinase_N_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GHMP_knse_ATP-bd_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone-fold UniProtKB/TrEMBL
  Histone_H2A/H2B/H3 UniProtKB/TrEMBL
  Histone_H3/CENP-A UniProtKB/TrEMBL
  Mevalonate/galactokinase UniProtKB/Swiss-Prot
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold_subgr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403694 UniProtKB/Swiss-Prot
NCBI Gene GALK1 ENTREZGENE
PANTHER PTHR10457:SF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GalKase_gal_bdg UniProtKB/Swiss-Prot
  GHMP_kinases_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GHMP_kinases_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone UniProtKB/TrEMBL
PIRSF Galactokinase UniProtKB/Swiss-Prot
PRINTS GALCTOKINASE UniProtKB/Swiss-Prot
  HISTONEH3 UniProtKB/TrEMBL
PROSITE GALACTOKINASE UniProtKB/Swiss-Prot
  GHMP_KINASES_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HISTONE_H3_1 UniProtKB/TrEMBL
  HISTONE_H3_2 UniProtKB/TrEMBL
SMART SM00428 UniProtKB/TrEMBL
Superfamily-SCOP SSF47113 UniProtKB/TrEMBL
  SSF54211 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55060 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs gal_kin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5F4BTW0_CANLF UniProtKB/TrEMBL
  A0A5F4C483_CANLF UniProtKB/TrEMBL
  GALK1_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:41081 ENTREZGENE