EXOC8 (exocyst complex component 8) - Rat Genome Database

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Gene: EXOC8 (exocyst complex component 8) Canis lupus familiaris
Analyze
Symbol: EXOC8
Name: exocyst complex component 8
RGD ID: 12329057
Description: ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); small GTPase binding (ortholog); INVOLVED IN endosome organization (ortholog); exocytosis (ortholog); extracellular matrix disassembly (ortholog); ASSOCIATED WITH Actin-Accumulation Myopathy (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cell leading edge (ortholog); exocyst (ortholog); late endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.148,133,526 - 8,138,185 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl48,133,670 - 8,135,853 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha48,125,862 - 8,130,738 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.048,158,970 - 8,163,846 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.148,162,330 - 8,167,207 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.048,284,329 - 8,289,206 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.048,512,727 - 8,517,604 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EXOC8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.148,133,526 - 8,138,185 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl48,133,670 - 8,135,853 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha48,125,862 - 8,130,738 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.048,158,970 - 8,163,846 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.148,162,330 - 8,167,207 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.048,284,329 - 8,289,206 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.048,512,727 - 8,517,604 (+)NCBIUU_Cfam_GSD_1.0
EXOC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381231,332,753 - 231,337,852 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1231,332,753 - 231,337,852 (-)EnsemblGRCh38hg38GRCh38
GRCh371231,468,499 - 231,473,598 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361229,535,103 - 229,540,201 (-)NCBINCBI36Build 36hg18NCBI36
Build 341227,775,217 - 227,780,313NCBI
Celera1204,733,352 - 204,738,448 (-)NCBICelera
Cytogenetic Map1q42.2NCBI
HuRef1201,951,802 - 201,956,897 (-)NCBIHuRef
CHM1_11232,742,131 - 232,747,227 (-)NCBICHM1_1
T2T-CHM13v2.01230,716,003 - 230,721,102 (-)NCBIT2T-CHM13v2.0
Exoc8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398125,617,038 - 125,624,444 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8125,619,847 - 125,624,444 (-)EnsemblGRCm39 Ensembl
GRCm388124,890,299 - 124,897,705 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8124,893,108 - 124,897,705 (-)EnsemblGRCm38mm10GRCm38
MGSCv378127,414,199 - 127,421,605 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368127,779,198 - 127,783,795 (-)NCBIMGSCv36mm8
Celera8129,198,972 - 129,206,398 (-)NCBICelera
Cytogenetic Map8E2NCBI
cM Map872.82NCBI
Exoc8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81969,752,387 - 69,754,876 (-)NCBIGRCr8
mRatBN7.21952,855,010 - 52,857,499 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1952,852,578 - 52,857,491 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1959,639,787 - 59,642,276 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01960,490,839 - 60,493,328 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01962,566,254 - 62,568,743 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01957,647,305 - 57,649,794 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1957,647,291 - 57,649,827 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01968,360,544 - 68,363,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41955,066,272 - 55,068,761 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11955,071,156 - 55,073,642 (-)NCBI
Celera1952,222,177 - 52,224,666 (-)NCBICelera
Cytogenetic Map19q12NCBI
Exoc8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554927,477,015 - 7,479,165 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554927,476,866 - 7,481,186 (+)NCBIChiLan1.0ChiLan1.0
EXOC8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2117,866,326 - 17,871,305 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1118,061,958 - 18,070,969 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01206,884,334 - 206,889,753 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11211,908,975 - 211,914,100 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1211,911,802 - 211,913,979 (-)Ensemblpanpan1.1panPan2
Exoc8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934443,238,232 - 43,240,797 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648419,403,458 - 19,405,197 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648419,403,458 - 19,407,202 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOC8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1459,192,434 - 59,197,542 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11459,192,345 - 59,197,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21463,861,048 - 63,866,149 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EXOC8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12568,594,174 - 68,599,236 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2568,596,957 - 68,599,134 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605570,502,324 - 70,507,389 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exoc8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477518,397,673 - 18,399,823 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477518,397,418 - 18,403,669 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EXOC8
22 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 5 22 6 6 6 6 6 12 8 10 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000018726   ⟹   ENSCAFP00000017348
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl48,133,670 - 8,135,853 (+)Ensembl
RefSeq Acc Id: XM_005618821   ⟹   XP_005618878
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.148,133,526 - 8,138,185 (+)NCBI
Dog10K_Boxer_Tasha48,125,862 - 8,130,738 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038472889   ⟹   XP_038328817
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.148,162,330 - 8,167,207 (+)NCBI
RefSeq Acc Id: XM_038533911   ⟹   XP_038389839
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.048,512,727 - 8,517,604 (+)NCBI
RefSeq Acc Id: XM_038598229   ⟹   XP_038454157
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.048,284,329 - 8,289,206 (+)NCBI
RefSeq Acc Id: XM_038662536   ⟹   XP_038518464
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.048,158,970 - 8,163,846 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005618878   ⟸   XM_005618821
- UniProtKB: A0A8C0NJH9 (UniProtKB/TrEMBL),   A0A8C0R8X3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000017348   ⟸   ENSCAFT00000018726
RefSeq Acc Id: XP_038328817   ⟸   XM_038472889
RefSeq Acc Id: XP_038454157   ⟸   XM_038598229
RefSeq Acc Id: XP_038518464   ⟸   XM_038662536
- UniProtKB: A0A8C0NJH9 (UniProtKB/TrEMBL),   A0A8C0R8X3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038389839   ⟸   XM_038533911
- UniProtKB: A0A8C0NJH9 (UniProtKB/TrEMBL),   A0A8C0R8X3 (UniProtKB/TrEMBL)
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011797 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030015907 UniProtKB/TrEMBL
  ENSCAFG00040003096 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000018726.5 UniProtKB/TrEMBL
  ENSCAFT00030029255.1 UniProtKB/TrEMBL
  ENSCAFT00040005889.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.1210 UniProtKB/TrEMBL
  1.20.58.1220 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Cullin_repeat-like_dom_sf UniProtKB/TrEMBL
  Exo84 UniProtKB/TrEMBL
  Exo84_C UniProtKB/TrEMBL
  Exo84_C_1 UniProtKB/TrEMBL
  Exo84_C_2 UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
KEGG Report cfa:488973 UniProtKB/TrEMBL
NCBI Gene EXOC8 ENTREZGENE
PANTHER EXOCYST COMPLEX COMPONENT 8 UniProtKB/TrEMBL
  PTHR21426 UniProtKB/TrEMBL
Pfam Exo84_C UniProtKB/TrEMBL
  Vps51 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF74788 UniProtKB/TrEMBL
UniProt A0A8C0NJH9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R8X3 ENTREZGENE
  A0A8P0NDQ5_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:40519 ENTREZGENE