Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PTGS1 (prostaglandin-endoperoxide synthase 1) Canis lupus familiaris
Analyze
Symbol: PTGS1
Name: prostaglandin-endoperoxide synthase 1
Description: ENCODES a protein that exhibits dioxygenase activity (inferred); heme binding (inferred); metal ion binding (inferred); INVOLVED IN cellular oxidant detoxification (inferred); cyclooxygenase pathway (inferred); inflammatory response (inferred); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Anaphylaxis (ortholog); bipolar disorder (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH acetylsalicylic acid; antipyrine; diclofenac
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: COX-1; COX-3; COX1; cyclooxygenase; Cyclooxygenase-1; PGH synthase 1; PGHS-1; PHS 1; prostaglandin G/H synthase 1; Prostaglandin H2 synthase 1
Orthologs:
Homo sapiens (human) : PTGS1 (prostaglandin-endoperoxide synthase 1)  HGNC  Alliance
Mus musculus (house mouse) : Ptgs1 (prostaglandin-endoperoxide synthase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ptgs1 (prostaglandin-endoperoxide synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptgs1 (prostaglandin-endoperoxide synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGS1 (prostaglandin-endoperoxide synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptgs1 (prostaglandin-endoperoxide synthase 1)
Sus scrofa (pig) : PTGS1 (prostaglandin-endoperoxide synthase 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1960,195,118 - 60,216,847 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog Cytomap9 NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on PTGS1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12328669
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.