RAB40C (RAB40C, member RAS oncogene family) - Rat Genome Database

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Gene: RAB40C (RAB40C, member RAS oncogene family) Canis lupus familiaris
Analyze
Symbol: RAB40C
Name: RAB40C, member RAS oncogene family
RGD ID: 12326980
Description: ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); INVOLVED IN intracellular signal transduction (inferred); protein ubiquitination (inferred); ASSOCIATED WITH epilepsy (ortholog); idiopathic generalized epilepsy (ortholog); short-rib thoracic dysplasia 9 with or without polydactyly (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rab-40C
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,937,858 - 39,968,042 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,939,004 - 39,945,765 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,201,465 - 41,228,245 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,280,019 - 40,306,809 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,280,023 - 40,307,845 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,968,542 - 39,995,318 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,928,729 - 39,955,488 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,407,910 - 40,434,695 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
GDP binding  (ISO)
GTP binding  (IEA,ISO)
GTPase activity  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAB40C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,937,858 - 39,968,042 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,939,004 - 39,945,765 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,201,465 - 41,228,245 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,280,019 - 40,306,809 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,280,023 - 40,307,845 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,968,542 - 39,995,318 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,928,729 - 39,955,488 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,407,910 - 40,434,695 (-)NCBIUU_Cfam_GSD_1.0
RAB40C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816589,357 - 629,268 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16589,357 - 629,272 (+)EnsemblGRCh38hg38GRCh38
GRCh3716639,357 - 679,268 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616580,177 - 619,273 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416580,179 - 619,272NCBI
Celera16840,134 - 879,407 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16561,196 - 600,572 (+)NCBIHuRef
CHM1_116639,212 - 679,111 (+)NCBICHM1_1
T2T-CHM13v2.016593,278 - 633,302 (+)NCBIT2T-CHM13v2.0
Rab40c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,101,088 - 26,138,688 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,101,088 - 26,138,701 (-)EnsemblGRCm39 Ensembl
GRCm381725,882,114 - 25,919,714 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,882,114 - 25,919,727 (-)EnsemblGRCm38mm10GRCm38
MGSCv371726,019,059 - 26,056,659 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361725,609,714 - 25,647,302 (-)NCBIMGSCv36mm8
Celera1726,415,170 - 26,452,734 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.97NCBI
Rab40c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,405,436 - 15,440,659 (-)NCBIGRCr8
mRatBN7.21014,900,926 - 14,936,153 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,900,929 - 14,936,557 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,641,467 - 19,675,115 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,130,345 - 19,163,990 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,630,680 - 14,664,091 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,247,913 - 15,283,111 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,247,914 - 15,282,951 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,060,856 - 15,096,137 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,147,861 - 15,181,653 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11015,147,860 - 15,181,653 (-)NCBI
Celera1014,571,341 - 14,604,815 (-)NCBICelera
Cytogenetic Map10q12NCBI
Rab40c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,577,843 - 16,614,639 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,577,843 - 16,614,132 (-)NCBIChiLan1.0ChiLan1.0
RAB40C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218831,336 - 869,340 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,615,216 - 4,653,206 (+)NCBINHGRI_mPanPan1
PanPan1.116600,153 - 642,365 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16606,023 - 640,714 (+)Ensemblpanpan1.1panPan2
Rab40c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,277,803 - 112,311,387 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501373,859 - 409,267 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936501375,663 - 409,243 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB40C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,140,561 - 41,160,077 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,140,557 - 41,160,101 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,328,868 - 41,330,727 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAB40C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15511,517 - 545,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5511,660 - 544,225 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,589,408 - 30,648,400 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab40c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,403,374 - 1,442,382 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249131,402,655 - 1,441,509 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RAB40C
213 total Variants

Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005622105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038479645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038479646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038540924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038540925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038551303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038551306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038605049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038605050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038669725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038669726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000066249   ⟹   ENSCAFP00000060786
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl639,939,004 - 39,945,765 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845049379   ⟹   ENSCAFP00845038743
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl640,280,023 - 40,307,845 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845049427   ⟹   ENSCAFP00845038781
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl640,280,023 - 40,306,825 (-)Ensembl
RefSeq Acc Id: XM_038479645   ⟹   XP_038335573
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1639,968,542 - 39,995,318 (-)NCBI
RefSeq Acc Id: XM_038479646   ⟹   XP_038335574
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1639,968,542 - 39,976,460 (-)NCBI
RefSeq Acc Id: XM_038540924   ⟹   XP_038396852
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0640,407,910 - 40,434,695 (-)NCBI
RefSeq Acc Id: XM_038540925   ⟹   XP_038396853
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0640,407,910 - 40,415,828 (-)NCBI
RefSeq Acc Id: XM_038551303   ⟹   XP_038407231
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha641,201,465 - 41,228,245 (-)NCBI
RefSeq Acc Id: XM_038551306   ⟹   XP_038407234
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha641,201,465 - 41,209,383 (-)NCBI
RefSeq Acc Id: XM_038605049   ⟹   XP_038460977
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0639,928,729 - 39,955,488 (-)NCBI
RefSeq Acc Id: XM_038605050   ⟹   XP_038460978
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0639,928,729 - 39,936,648 (-)NCBI
RefSeq Acc Id: XM_038669725   ⟹   XP_038525653
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0640,280,019 - 40,306,809 (-)NCBI
RefSeq Acc Id: XM_038669726   ⟹   XP_038525654
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0640,280,019 - 40,287,938 (-)NCBI
Ensembl Acc Id: ENSCAFP00000060786   ⟸   ENSCAFT00000066249
RefSeq Acc Id: XP_038335573   ⟸   XM_038479645
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038335574   ⟸   XM_038479646
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038460977   ⟸   XM_038605049
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038460978   ⟸   XM_038605050
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038525653   ⟸   XM_038669725
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K9P5 (UniProtKB/TrEMBL),   A0A8C0MW49 (UniProtKB/TrEMBL),   A0A8I3SB97 (UniProtKB/TrEMBL),   A0A8C0MZ34 (UniProtKB/TrEMBL),   A0A8I3PVM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038525654   ⟸   XM_038669726
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RHM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407231   ⟸   XM_038551303
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K9P5 (UniProtKB/TrEMBL),   A0A8C0MW49 (UniProtKB/TrEMBL),   A0A8I3SB97 (UniProtKB/TrEMBL),   A0A8C0MZ34 (UniProtKB/TrEMBL),   A0A8I3PVM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407234   ⟸   XM_038551306
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RHM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038396852   ⟸   XM_038540924
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K9P5 (UniProtKB/TrEMBL),   A0A8C0MW49 (UniProtKB/TrEMBL),   A0A8C0MZ34 (UniProtKB/TrEMBL),   A0A8I3PVM2 (UniProtKB/TrEMBL),   A0A8I3SB97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038396853   ⟸   XM_038540925
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RHM4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845038781   ⟸   ENSCAFT00845049427
Ensembl Acc Id: ENSCAFP00845038743   ⟸   ENSCAFT00845049379
Protein Domains
SOCS box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000041318 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010968 UniProtKB/TrEMBL
  ENSCAFG00040003978 UniProtKB/TrEMBL
  ENSCAFG00845027974 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000066249.2 UniProtKB/TrEMBL
  ENSCAFT00000099181.1 UniProtKB/TrEMBL
  ENSCAFT00030020311.1 UniProtKB/TrEMBL
  ENSCAFT00030020388.1 UniProtKB/TrEMBL
  ENSCAFT00030020478.1 UniProtKB/TrEMBL
  ENSCAFT00040007584.1 UniProtKB/TrEMBL
  ENSCAFT00845049379.1 UniProtKB/TrEMBL
  ENSCAFT00845049427 ENTREZGENE
  ENSCAFT00845049427.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Rab UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
  SOCS_box-like_dom_sf UniProtKB/TrEMBL
NCBI Gene RAB40C ENTREZGENE
PANTHER LD44762P UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-40C UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
Superfamily-SCOP SSF158235 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0K9P5 ENTREZGENE
  A0A8C0MW49 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MZ34 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RHM4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PVM2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3SB97 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:112753 ENTREZGENE