TMEM225 (transmembrane protein 225) - Rat Genome Database

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Gene: TMEM225 (transmembrane protein 225) Canis lupus familiaris
Analyze
Symbol: TMEM225
Name: transmembrane protein 225
RGD ID: 12326953
Description: ENCODES a protein that exhibits protein phosphatase 1 binding (ortholog); protein phosphatase inhibitor activity (ortholog); ASSOCIATED WITH Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN inner acrosomal membrane (ortholog); outer acrosomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1510,570,153 - 10,574,469 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl510,570,197 - 10,572,865 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha510,626,331 - 10,630,640 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0510,519,725 - 10,524,033 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl510,519,769 - 10,522,436 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1510,586,432 - 10,590,739 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0510,555,339 - 10,559,648 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0510,600,697 - 10,605,006 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TMEM225
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1510,570,153 - 10,574,469 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl510,570,197 - 10,572,865 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha510,626,331 - 10,630,640 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0510,519,725 - 10,524,033 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl510,519,769 - 10,522,436 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1510,586,432 - 10,590,739 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0510,555,339 - 10,559,648 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0510,600,697 - 10,605,006 (-)NCBIUU_Cfam_GSD_1.0
TMEM225
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811123,882,920 - 123,885,670 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11123,882,920 - 123,885,670 (-)EnsemblGRCh38hg38GRCh38
GRCh3711123,753,627 - 123,756,377 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611123,258,843 - 123,261,550 (-)NCBINCBI36Build 36hg18NCBI36
Celera11120,913,041 - 120,915,748 (-)NCBICelera
Cytogenetic Map11q24.1NCBI
HuRef11119,693,896 - 119,696,603 (-)NCBIHuRef
CHM1_111123,640,060 - 123,642,766 (-)NCBICHM1_1
T2T-CHM13v2.011123,911,680 - 123,914,430 (-)NCBIT2T-CHM13v2.0
Tmem225
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39940,059,418 - 40,062,176 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl940,059,418 - 40,062,170 (+)EnsemblGRCm39 Ensembl
GRCm38940,148,122 - 40,150,880 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl940,148,122 - 40,150,874 (+)EnsemblGRCm38mm10GRCm38
MGSCv37939,955,707 - 39,958,465 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36939,898,693 - 39,901,451 (+)NCBIMGSCv36mm8
Celera937,388,547 - 37,391,300 (+)NCBICelera
Cytogenetic Map9A5.1NCBI
cM Map921.42NCBI
Tmem225
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8849,394,638 - 49,397,196 (+)NCBIGRCr8
mRatBN7.2840,497,483 - 40,500,041 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl840,497,483 - 40,500,041 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx846,004,367 - 46,007,043 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0844,282,954 - 44,285,630 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0842,150,560 - 42,153,236 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0844,001,199 - 44,003,757 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl844,001,096 - 44,004,044 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0861,532,196 - 61,534,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4843,096,844 - 43,099,402 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera840,113,816 - 40,116,373 (+)NCBICelera
Cytogenetic Map8q22NCBI
Tmem225
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541224,544,480 - 24,547,498 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541224,544,669 - 24,547,471 (-)NCBIChiLan1.0ChiLan1.0
TMEM225
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29124,576,749 - 124,583,850 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111125,681,335 - 125,688,434 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011118,711,832 - 118,715,420 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111122,628,709 - 122,631,425 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11122,628,109 - 122,631,425 (-)Ensemblpanpan1.1panPan2
Tmem225
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947105,358,796 - 105,361,475 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365428,280,386 - 8,282,671 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM225
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1950,730,121 - 50,732,787 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2956,019,431 - 56,022,233 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM225
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11115,195,428 - 115,199,208 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1115,195,646 - 115,198,074 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604310,913,628 - 10,916,820 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem225
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248801,287,126 - 1,295,505 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TMEM225
59 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 8
Low 1
Below cutoff 5 5 11 4 5 4 2 4 8 6 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022418163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022418164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022418165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_847608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000045832   ⟹   ENSCAFP00000039208
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl510,570,197 - 10,572,865 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845021631   ⟹   ENSCAFP00845017002
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl510,519,769 - 10,522,436 (-)Ensembl
RefSeq Acc Id: XM_022418163   ⟹   XP_022273871
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1510,570,153 - 10,574,469 (-)NCBI
Dog10K_Boxer_Tasha510,626,331 - 10,630,640 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022418164   ⟹   XP_022273872
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1510,570,153 - 10,572,633 (-)NCBI
Dog10K_Boxer_Tasha510,626,331 - 10,628,838 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022418165   ⟹   XP_022273873
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1510,570,153 - 10,572,623 (-)NCBI
Dog10K_Boxer_Tasha510,626,331 - 10,628,838 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038474699   ⟹   XP_038330627
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1510,586,432 - 10,590,739 (-)NCBI
RefSeq Acc Id: XM_038474700   ⟹   XP_038330628
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1510,586,432 - 10,589,194 (-)NCBI
RefSeq Acc Id: XM_038474701   ⟹   XP_038330629
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1510,586,432 - 10,588,940 (-)NCBI
RefSeq Acc Id: XM_038474702   ⟹   XP_038330630
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1510,586,432 - 10,588,940 (-)NCBI
RefSeq Acc Id: XM_038535828   ⟹   XP_038391756
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0510,600,697 - 10,605,006 (-)NCBI
RefSeq Acc Id: XM_038535829   ⟹   XP_038391757
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0510,600,697 - 10,603,457 (-)NCBI
RefSeq Acc Id: XM_038535830   ⟹   XP_038391758
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0510,600,697 - 10,603,203 (-)NCBI
RefSeq Acc Id: XM_038535831   ⟹   XP_038391759
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0510,600,697 - 10,603,459 (-)NCBI
RefSeq Acc Id: XM_038535832   ⟹   XP_038391760
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0510,600,697 - 10,603,203 (-)NCBI
RefSeq Acc Id: XM_038600032   ⟹   XP_038455960
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0510,555,339 - 10,559,648 (-)NCBI
RefSeq Acc Id: XM_038600033   ⟹   XP_038455961
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0510,555,339 - 10,558,100 (-)NCBI
RefSeq Acc Id: XM_038600034   ⟹   XP_038455962
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0510,555,339 - 10,558,101 (-)NCBI
RefSeq Acc Id: XM_038600035   ⟹   XP_038455963
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0510,555,339 - 10,558,102 (-)NCBI
RefSeq Acc Id: XM_038664573   ⟹   XP_038520501
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0510,519,725 - 10,524,033 (-)NCBI
RefSeq Acc Id: XM_038664574   ⟹   XP_038520502
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0510,519,725 - 10,522,485 (-)NCBI
RefSeq Acc Id: XM_038664575   ⟹   XP_038520503
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0510,519,725 - 10,522,231 (-)NCBI
RefSeq Acc Id: XM_038664576   ⟹   XP_038520504
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0510,519,725 - 10,522,231 (-)NCBI
RefSeq Acc Id: XM_847608   ⟹   XP_852701
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1510,570,153 - 10,572,879 (-)NCBI
Dog10K_Boxer_Tasha510,626,331 - 10,629,092 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_852701   ⟸   XM_847608
- Peptide Label: isoform X4
- UniProtKB: A0A8C0LWL5 (UniProtKB/TrEMBL),   A0A8P0NQP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022273871   ⟸   XM_022418163
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_022273872   ⟸   XM_022418164
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_022273873   ⟸   XM_022418165
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000039208   ⟸   ENSCAFT00000045832
RefSeq Acc Id: XP_038330627   ⟸   XM_038474699
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038330628   ⟸   XM_038474700
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038330630   ⟸   XM_038474702
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038330629   ⟸   XM_038474701
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038455960   ⟸   XM_038600032
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038455963   ⟸   XM_038600035
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038455962   ⟸   XM_038600034
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038455961   ⟸   XM_038600033
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038520501   ⟸   XM_038664573
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038520502   ⟸   XM_038664574
- Peptide Label: isoform X4
- UniProtKB: A0A8C0KEK1 (UniProtKB/TrEMBL),   A0A8C0S6C2 (UniProtKB/TrEMBL),   A0A8I3NWU1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038520504   ⟸   XM_038664576
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038520503   ⟸   XM_038664575
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038391756   ⟸   XM_038535828
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038391759   ⟸   XM_038535831
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038391757   ⟸   XM_038535829
- Peptide Label: isoform X4
- UniProtKB: A0A8C0LWL5 (UniProtKB/TrEMBL),   A0A8P0NQP0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391760   ⟸   XM_038535832
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038391758   ⟸   XM_038535830
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCAFP00845017002   ⟸   ENSCAFT00845021631


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029049 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030000956 UniProtKB/TrEMBL
  ENSCAFG00040010189 UniProtKB/TrEMBL
  ENSCAFG00845012170 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000045832.3 UniProtKB/TrEMBL
  ENSCAFT00030001649.1 UniProtKB/TrEMBL
  ENSCAFT00040018951.1 UniProtKB/TrEMBL
  ENSCAFT00845021631 ENTREZGENE
  ENSCAFT00845021631.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.140.150 UniProtKB/TrEMBL
InterPro TMEM225 UniProtKB/TrEMBL
NCBI Gene TMEM225 ENTREZGENE
PANTHER PTHR36477 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 225 UniProtKB/TrEMBL
UniProt A0A8C0KEK1 ENTREZGENE
  A0A8C0LWL5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0S6C2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NWU1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NQP0 ENTREZGENE
UniProt Secondary A0A8P0NQP0 UniProtKB/TrEMBL
VGNC ID VGNC:47538 ENTREZGENE