DYNLL1 (dynein light chain LC8-type 1) - Rat Genome Database

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Gene: DYNLL1 (dynein light chain LC8-type 1) Canis lupus familiaris
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Symbol: DYNLL1
Name: dynein light chain LC8-type 1
RGD ID: 12325624
Description: ENCODES a protein that exhibits deoxyribonuclease inhibitor activity (ortholog); dynein intermediate chain binding (ortholog); enzyme binding (ortholog); INVOLVED IN intraciliary retrograde transport (ortholog); mitocytosis (ortholog); motile cilium assembly (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH brain ischemia (ortholog); cardiac arrest (ortholog); congestive heart failure (ortholog); FOUND IN axon cytoplasm (ortholog); COP9 signalosome (ortholog); cytoplasmic dynein complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dynein light chain 1, cytoplasmic
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12616,369,878 - 16,402,302 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,398,886 - 16,402,021 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,399,889 - 16,402,458 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2616,373,479 - 16,405,461 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02616,637,042 - 16,669,452 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2616,667,035 - 16,670,006 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12616,597,102 - 16,629,472 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02616,673,811 - 16,705,772 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02616,715,648 - 16,747,621 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DYNLL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12616,369,878 - 16,402,302 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,398,886 - 16,402,021 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,399,889 - 16,402,458 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2616,373,479 - 16,405,461 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02616,637,042 - 16,669,452 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2616,667,035 - 16,670,006 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12616,597,102 - 16,629,472 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02616,673,811 - 16,705,772 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02616,715,648 - 16,747,621 (+)NCBIUU_Cfam_GSD_1.0
DYNLL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812120,469,842 - 120,498,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12120,469,850 - 120,498,493 (+)EnsemblGRCh38hg38GRCh38
GRCh3712120,907,645 - 120,936,296 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612119,392,043 - 119,420,681 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412119,396,652 - 119,399,010NCBI
Celera12120,542,375 - 120,570,391 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12117,917,550 - 117,946,088 (+)NCBIHuRef
CHM1_112120,876,465 - 120,905,100 (+)NCBICHM1_1
T2T-CHM13v2.012120,459,024 - 120,487,665 (+)NCBIT2T-CHM13v2.0
Dynll1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395115,435,129 - 115,438,995 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5115,435,169 - 115,439,058 (-)EnsemblGRCm39 Ensembl
GRCm385115,297,110 - 115,300,990 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,297,110 - 115,300,999 (-)EnsemblGRCm38mm10GRCm38
MGSCv375115,747,119 - 115,750,999 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365115,559,422 - 115,561,933 (-)NCBIMGSCv36mm8
Celera5112,394,410 - 112,398,301 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map556.04NCBI
Dynll1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81246,945,291 - 46,976,867 (+)NCBIGRCr8
mRatBN7.21241,312,365 - 41,316,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,312,367 - 41,314,741 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,479,075 - 42,481,446 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,092,738 - 43,095,109 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,153,290 - 42,155,661 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,074,200 - 47,076,573 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,074,200 - 47,076,572 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01248,867,516 - 48,869,889 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,580,542 - 42,582,915 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,443,929 - 42,446,302 (+)NCBI
Celera1242,933,102 - 42,935,475 (+)NCBICelera
Cytogenetic Map12q16NCBI
Dynll1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545511,148,047 - 11,150,859 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545511,148,041 - 11,150,860 (-)NCBIChiLan1.0ChiLan1.0
DYNLL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210128,539,098 - 128,567,509 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112128,535,475 - 128,563,886 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,078,401 - 118,080,822 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112121,452,118 - 121,454,550 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12121,452,118 - 121,454,550 (+)Ensemblpanpan1.1panPan2
Dynll1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118145,952,956 - 145,985,917 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936668448,489 - 500,800 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936668451,846 - 484,841 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNLL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1440,455,985 - 40,459,104 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11440,455,954 - 40,458,352 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21442,956,562 - 42,958,960 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYNLL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111115,851,020 - 115,855,526 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11115,851,381 - 115,851,647 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037129,247,006 - 129,249,444 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dynll1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474713,169,865 - 13,172,525 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474713,169,865 - 13,172,592 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DYNLL1
395 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000016382   ⟹   ENSCAFP00000015154
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2616,398,886 - 16,402,021 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000068433   ⟹   ENSCAFP00000056432
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2616,399,889 - 16,402,458 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845052824   ⟹   ENSCAFP00845041469
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2616,667,035 - 16,670,006 (+)Ensembl
RefSeq Acc Id: XM_038436936   ⟹   XP_038292864
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02616,666,976 - 16,669,452 (+)NCBI
RefSeq Acc Id: XM_038436937   ⟹   XP_038292865
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02616,637,042 - 16,669,452 (+)NCBI
RefSeq Acc Id: XM_038511829   ⟹   XP_038367757
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12616,626,998 - 16,629,472 (+)NCBI
RefSeq Acc Id: XM_038511830   ⟹   XP_038367758
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12616,597,102 - 16,629,472 (+)NCBI
RefSeq Acc Id: XM_038575327   ⟹   XP_038431255
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02616,745,147 - 16,747,621 (+)NCBI
RefSeq Acc Id: XM_038575328   ⟹   XP_038431256
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02616,715,648 - 16,747,621 (+)NCBI
RefSeq Acc Id: XM_038639514   ⟹   XP_038495442
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02616,703,298 - 16,705,772 (+)NCBI
RefSeq Acc Id: XM_038639515   ⟹   XP_038495443
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02616,673,811 - 16,705,772 (+)NCBI
RefSeq Acc Id: XM_846171   ⟹   XP_851264
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12616,399,834 - 16,402,302 (+)NCBI
Dog10K_Boxer_Tasha2616,402,987 - 16,405,461 (+)NCBI
Sequence:
RefSeq Acc Id: XM_858324   ⟹   XP_863417
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12616,369,878 - 16,402,302 (+)NCBI
Dog10K_Boxer_Tasha2616,373,479 - 16,405,461 (+)NCBI
Sequence:
RefSeq Acc Id: XP_863417   ⟸   XM_858324
- UniProtKB: A0A8C0L8K1 (UniProtKB/TrEMBL),   A0A8C0T786 (UniProtKB/TrEMBL),   A0A8I3Q4C7 (UniProtKB/TrEMBL),   A0A8C0RZV7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_851264   ⟸   XM_846171
- UniProtKB: A0A8C0L8K1 (UniProtKB/TrEMBL),   A0A8C0T786 (UniProtKB/TrEMBL),   A0A8I3Q4C7 (UniProtKB/TrEMBL),   A0A8C0RZV7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000015154   ⟸   ENSCAFT00000016382
Ensembl Acc Id: ENSCAFP00000056432   ⟸   ENSCAFT00000068433
RefSeq Acc Id: XP_038367758   ⟸   XM_038511830
RefSeq Acc Id: XP_038367757   ⟸   XM_038511829
RefSeq Acc Id: XP_038495443   ⟸   XM_038639515
RefSeq Acc Id: XP_038495442   ⟸   XM_038639514
RefSeq Acc Id: XP_038292865   ⟸   XM_038436937
- UniProtKB: A0A8C0L8K1 (UniProtKB/TrEMBL),   A0A8C0T786 (UniProtKB/TrEMBL),   A0A8I3Q4C7 (UniProtKB/TrEMBL),   A0A8C0RZV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038292864   ⟸   XM_038436936
- UniProtKB: A0A8C0L8K1 (UniProtKB/TrEMBL),   A0A8C0T786 (UniProtKB/TrEMBL),   A0A8I3Q4C7 (UniProtKB/TrEMBL),   A0A8C0RZV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431256   ⟸   XM_038575328
- UniProtKB: A0A8C0L8K1 (UniProtKB/TrEMBL),   A0A8C0RZV7 (UniProtKB/TrEMBL),   A0A8C0T786 (UniProtKB/TrEMBL),   A0A8I3Q4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431255   ⟸   XM_038575327
- UniProtKB: A0A8C0L8K1 (UniProtKB/TrEMBL),   A0A8C0RZV7 (UniProtKB/TrEMBL),   A0A8C0T786 (UniProtKB/TrEMBL),   A0A8I3Q4C7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845041469   ⟸   ENSCAFT00845052824


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010318 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00000046342 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030023626 UniProtKB/TrEMBL
  ENSCAFG00030023649 UniProtKB/TrEMBL
  ENSCAFG00040007472 UniProtKB/TrEMBL
  ENSCAFG00040020338 UniProtKB/TrEMBL
  ENSCAFG00845029827 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000016382.5 UniProtKB/TrEMBL
  ENSCAFT00000068433.2 UniProtKB/TrEMBL
  ENSCAFT00030043449.1 UniProtKB/TrEMBL
  ENSCAFT00030043487.1 UniProtKB/TrEMBL
  ENSCAFT00040013899.1 UniProtKB/TrEMBL
  ENSCAFT00040037629.1 UniProtKB/TrEMBL
  ENSCAFT00845052824 ENTREZGENE
  ENSCAFT00845052824.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.740.10 UniProtKB/TrEMBL
InterPro DLC_sf UniProtKB/TrEMBL
  Dynein_light_1/2_CS UniProtKB/TrEMBL
  Dynein_light_chain_typ-1/2 UniProtKB/TrEMBL
KEGG Report cfa:609233 UniProtKB/TrEMBL
NCBI Gene DYNLL1 ENTREZGENE
PANTHER DYNEIN LIGHT CHAIN UniProtKB/TrEMBL
  DYNEIN LIGHT CHAIN UniProtKB/TrEMBL
  DYNEIN LIGHT CHAIN 1, CYTOPLASMIC UniProtKB/TrEMBL
  PTHR11886 UniProtKB/TrEMBL
Pfam Dynein_light UniProtKB/TrEMBL
PROSITE DYNEIN_LIGHT_1 UniProtKB/TrEMBL
SMART Dynein_light UniProtKB/TrEMBL
Superfamily-SCOP SSF54648 UniProtKB/TrEMBL
UniProt A0A8C0L8K1 ENTREZGENE
  A0A8C0PA21_CANLF UniProtKB/TrEMBL
  A0A8C0RZV7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0T786 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q4C7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40150 ENTREZGENE