RCAN2 (regulator of calcineurin 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: RCAN2 (regulator of calcineurin 2) Canis lupus familiaris
Analyze
Symbol: RCAN2
Name: regulator of calcineurin 2
RGD ID: 12324978
Description: ENCODES a protein that exhibits calcium-dependent protein serine/threonine phosphatase regulator activity (inferred); nucleic acid binding (inferred); INVOLVED IN calcineurin-NFAT signaling cascade (ortholog); locomotion involved in locomotory behavior (ortholog); Notch signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calcipressin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11214,427,095 - 14,647,327 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1214,428,406 - 14,687,241 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1214,458,631 - 14,718,983 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01214,927,188 - 15,187,200 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1214,927,180 - 15,187,355 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11214,442,961 - 14,703,496 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01214,531,756 - 14,791,823 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01214,628,322 - 14,888,571 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RCAN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11214,427,095 - 14,647,327 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1214,428,406 - 14,687,241 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1214,458,631 - 14,718,983 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01214,927,188 - 15,187,200 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1214,927,180 - 15,187,355 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11214,442,961 - 14,703,496 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01214,531,756 - 14,791,823 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01214,628,322 - 14,888,571 (-)NCBIUU_Cfam_GSD_1.0
RCAN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38646,220,736 - 46,491,970 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl646,220,736 - 46,491,972 (-)EnsemblGRCh38hg38GRCh38
GRCh37646,188,473 - 46,459,707 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,296,428 - 46,401,490 (-)NCBINCBI36Build 36hg18NCBI36
Build 34646,296,433 - 46,401,364NCBI
Celera647,741,020 - 47,846,061 (-)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef645,911,564 - 46,182,793 (-)NCBIHuRef
CHM1_1646,191,709 - 46,463,038 (-)NCBICHM1_1
T2T-CHM13v2.0646,055,860 - 46,329,613 (-)NCBIT2T-CHM13v2.0
Rcan2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391744,112,243 - 44,350,407 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1744,112,242 - 44,350,407 (+)EnsemblGRCm39 Ensembl
GRCm381743,801,352 - 44,039,516 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1743,801,351 - 44,039,516 (+)EnsemblGRCm38mm10GRCm38
MGSCv371743,938,800 - 44,176,465 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361743,264,906 - 43,502,571 (+)NCBIMGSCv36mm8
Celera1747,226,766 - 47,458,244 (+)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1719.77NCBI
Rcan2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,456,861 - 24,674,234 (-)NCBIGRCr8
mRatBN7.2916,959,478 - 17,174,823 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl916,959,480 - 17,174,856 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx925,543,367 - 25,758,360 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,617,888 - 30,832,887 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0928,907,100 - 29,122,117 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,518,568 - 19,749,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,518,558 - 19,749,145 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,397,065 - 18,626,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4912,623,121 - 12,853,302 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1912,620,444 - 12,850,624 (-)NCBI
Celera914,685,543 - 14,899,643 (-)NCBICelera
Cytogenetic Map9q13NCBI
Rcan2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,243,143 - 11,405,795 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543711,243,195 - 11,406,488 (-)NCBIChiLan1.0ChiLan1.0
RCAN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2560,713,940 - 60,987,123 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1656,580,011 - 56,853,215 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0645,801,389 - 46,074,620 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1647,074,850 - 47,347,556 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl647,074,850 - 47,312,149 (-)Ensemblpanpan1.1panPan2
Rcan2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494649,849,314 - 50,090,256 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647613,915,701 - 14,110,891 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647613,869,797 - 14,110,892 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RCAN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl740,980,527 - 41,282,835 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1740,979,814 - 41,282,869 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2747,364,244 - 47,451,587 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RCAN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11725,775,137 - 26,034,443 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1725,939,629 - 26,034,448 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604446,223,466 - 46,511,471 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rcan2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475414,086,096 - 14,250,567 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475414,086,947 - 14,250,473 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RCAN2
2912 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 5 11 4 6 12 2 4
Low 1 10 5 2 5 6 6 10 2
Below cutoff 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014118488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014118489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038491977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038491979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038491980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038554239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038554240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038554241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038672391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038672401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038683695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038683696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038683697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000003202   ⟹   ENSCAFP00000002976
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1214,428,406 - 14,524,296 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000047949   ⟹   ENSCAFP00000039252
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1214,428,406 - 14,687,241 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845022817   ⟹   ENSCAFP00845017884
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1214,927,180 - 15,187,355 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845022842   ⟹   ENSCAFP00845017905
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1214,927,917 - 15,024,313 (-)Ensembl
RefSeq Acc Id: XM_014118489   ⟹   XP_013973964
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11214,427,095 - 14,524,327 (-)NCBI
Dog10K_Boxer_Tasha1214,458,631 - 14,555,814 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038491977   ⟹   XP_038347905
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11214,442,961 - 14,703,496 (-)NCBI
RefSeq Acc Id: XM_038491979   ⟹   XP_038347907
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11214,442,961 - 14,667,209 (-)NCBI
RefSeq Acc Id: XM_038491980   ⟹   XP_038347908
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11214,442,961 - 14,540,415 (-)NCBI
RefSeq Acc Id: XM_038554239   ⟹   XP_038410167
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01214,628,322 - 14,888,571 (-)NCBI
RefSeq Acc Id: XM_038554240   ⟹   XP_038410168
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01214,628,322 - 14,852,327 (-)NCBI
RefSeq Acc Id: XM_038554241   ⟹   XP_038410169
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01214,628,322 - 14,725,527 (-)NCBI
RefSeq Acc Id: XM_038618107   ⟹   XP_038474035
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01214,531,756 - 14,791,823 (-)NCBI
RefSeq Acc Id: XM_038618108   ⟹   XP_038474036
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01214,531,756 - 14,755,470 (-)NCBI
RefSeq Acc Id: XM_038618109   ⟹   XP_038474037
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01214,531,756 - 14,628,943 (-)NCBI
RefSeq Acc Id: XM_038672391   ⟹   XP_038528319
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1214,458,631 - 14,718,983 (-)NCBI
RefSeq Acc Id: XM_038672401   ⟹   XP_038528329
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1214,458,631 - 14,682,800 (-)NCBI
RefSeq Acc Id: XM_038683695   ⟹   XP_038539623
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01214,927,188 - 15,187,200 (-)NCBI
RefSeq Acc Id: XM_038683696   ⟹   XP_038539624
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01214,927,188 - 15,151,018 (-)NCBI
RefSeq Acc Id: XM_038683697   ⟹   XP_038539625
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01214,927,188 - 15,024,360 (-)NCBI
RefSeq Acc Id: XP_013973964   ⟸   XM_014118489
- Peptide Label: isoform X2
- UniProtKB: A0A8C0MK86 (UniProtKB/TrEMBL),   A0A8C0KFL3 (UniProtKB/TrEMBL),   A0A8I3NHX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000002976   ⟸   ENSCAFT00000003202
RefSeq Acc Id: ENSCAFP00000039252   ⟸   ENSCAFT00000047949
RefSeq Acc Id: XP_038347905   ⟸   XM_038491977
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038347907   ⟸   XM_038491979
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038347908   ⟸   XM_038491980
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038474035   ⟸   XM_038618107
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038474036   ⟸   XM_038618108
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038474037   ⟸   XM_038618109
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038539623   ⟸   XM_038683695
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KF11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038539624   ⟸   XM_038683696
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KF11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038539625   ⟸   XM_038683697
- Peptide Label: isoform X2
- UniProtKB: A0A8C0MK86 (UniProtKB/TrEMBL),   A0A8C0KFL3 (UniProtKB/TrEMBL),   A0A8I3NHX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038528319   ⟸   XM_038672391
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KF11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038528329   ⟸   XM_038672401
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KF11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038410167   ⟸   XM_038554239
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KF11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038410168   ⟸   XM_038554240
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KF11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038410169   ⟸   XM_038554241
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KFL3 (UniProtKB/TrEMBL),   A0A8C0MK86 (UniProtKB/TrEMBL),   A0A8I3NHX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845017884   ⟸   ENSCAFT00845022817
RefSeq Acc Id: ENSCAFP00845017905   ⟸   ENSCAFT00845022842


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002023 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006782 UniProtKB/TrEMBL
  ENSCAFG00040012761 UniProtKB/TrEMBL
  ENSCAFG00845012828 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003202.4 UniProtKB/TrEMBL
  ENSCAFT00000047949.4 UniProtKB/TrEMBL
  ENSCAFT00030012484.1 UniProtKB/TrEMBL
  ENSCAFT00030012524.1 UniProtKB/TrEMBL
  ENSCAFT00040023536.1 UniProtKB/TrEMBL
  ENSCAFT00040023580.1 UniProtKB/TrEMBL
  ENSCAFT00845022817.1 UniProtKB/TrEMBL
  ENSCAFT00845022842 ENTREZGENE
  ENSCAFT00845022842.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Calcipressin UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RCAN2_RRM UniProtKB/TrEMBL
KEGG Report cfa:609864 UniProtKB/TrEMBL
NCBI Gene RCAN2 ENTREZGENE
PANTHER PTHR10300 UniProtKB/TrEMBL
  PTHR10300:SF5 UniProtKB/TrEMBL
Pfam Calcipressin UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8C0KF11 ENTREZGENE
  A0A8C0KFL3 ENTREZGENE
  A0A8C0MK63_CANLF UniProtKB/TrEMBL
  A0A8C0MK86 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SF70_CANLF UniProtKB/TrEMBL
  A0A8I3NHX7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NQG5_CANLF UniProtKB/TrEMBL
  A0A8P0STJ3_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:45437 ENTREZGENE