LOC476645 (serine protease 45) - Rat Genome Database

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Gene: LOC476645 (serine protease 45) Canis lupus familiaris
Analyze
No known orthologs.
Symbol: LOC476645
Name: serine protease 45
RGD ID: 12324729
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); FOUND IN extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protease, serine 45; PRSS45; PRSS45P; serine protease 45, pseudogene
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,007,085 - 42,016,142 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,923,268 - 41,932,329 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02042,489,674 - 42,498,721 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12041,731,104 - 41,740,004 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02042,131,970 - 42,140,802 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02042,413,044 - 42,421,869 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Variants

.
Variants in LOC476645
142 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_038427966   ⟹   XP_038283894
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02042,489,674 - 42,498,721 (+)NCBI
RefSeq Acc Id: XM_038503621   ⟹   XP_038359549
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12041,731,104 - 41,740,004 (+)NCBI
RefSeq Acc Id: XM_038566645   ⟹   XP_038422573
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02042,413,044 - 42,421,869 (+)NCBI
RefSeq Acc Id: XM_038630789   ⟹   XP_038486717
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02042,131,970 - 42,140,802 (+)NCBI
RefSeq Acc Id: XM_533850   ⟹   XP_533850
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12042,007,085 - 42,016,142 (+)NCBI
Dog10K_Boxer_Tasha2041,923,268 - 41,932,329 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038283894 (Get FASTA)   NCBI Sequence Viewer  
  XP_038359549 (Get FASTA)   NCBI Sequence Viewer  
  XP_038422573 (Get FASTA)   NCBI Sequence Viewer  
  XP_038486717 (Get FASTA)   NCBI Sequence Viewer  
  XP_533850 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00030040415.1
Reference Protein Sequences
RefSeq Acc Id: XP_533850   ⟸   XM_533850
- UniProtKB: A0A8C0KLT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038359549   ⟸   XM_038503621
RefSeq Acc Id: XP_038486717   ⟸   XM_038630789
RefSeq Acc Id: XP_038283894   ⟸   XM_038427966
- UniProtKB: A0A8C0KLT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038422573   ⟸   XM_038566645
- UniProtKB: A0A8C0KLT3 (UniProtKB/TrEMBL),   A0A8C0PE82 (UniProtKB/TrEMBL)
Protein Domains
Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00030025070 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030046254.1 UniProtKB/TrEMBL
Gene3D-CATH Trypsin-like serine proteases UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
NCBI Gene PRSS45 ENTREZGENE
PANTHER SERINE PROTEASE 45-RELATED UniProtKB/TrEMBL
  TRYPTASE-RELATED UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP Trypsin-like serine proteases UniProtKB/TrEMBL
UniProt A0A8C0KLT3 ENTREZGENE
  A0A8C0PE82 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 LOC476645  serine protease 45  PRSS45  serine protease 45  Symbol and/or name change 5135510 APPROVED
2020-08-04 PRSS45  serine protease 45  PRSS45P  serine protease 45, pseudogene  Symbol and/or name change 5135510 APPROVED
2019-02-05 PRSS45P  serine protease 45, pseudogene  PRSS45  serine protease 45  Symbol and/or name change 5135510 APPROVED
2018-01-23 PRSS45  serine protease 45    protease, serine 45  Symbol and/or name change 5135510 APPROVED