CCDC59 (coiled-coil domain containing 59) - Rat Genome Database

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Gene: CCDC59 (coiled-coil domain containing 59) Canis lupus familiaris
Analyze
Symbol: CCDC59
Name: coiled-coil domain containing 59
RGD ID: 12322141
Description: ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: thyroid transcription factor 1-associated protein 26
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11524,364,510 - 24,373,567 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1524,364,779 - 24,373,419 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1524,795,481 - 24,804,911 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01524,743,406 - 24,752,836 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1524,743,676 - 24,752,295 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11524,320,972 - 24,330,182 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01524,369,767 - 24,379,043 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01524,610,635 - 24,620,062 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CCDC59
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11524,364,510 - 24,373,567 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1524,364,779 - 24,373,419 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1524,795,481 - 24,804,911 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01524,743,406 - 24,752,836 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1524,743,676 - 24,752,295 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11524,320,972 - 24,330,182 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01524,369,767 - 24,379,043 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01524,610,635 - 24,620,062 (-)NCBIUU_Cfam_GSD_1.0
CCDC59
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381282,352,303 - 82,358,805 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1282,223,681 - 82,358,805 (-)EnsemblGRCh38hg38GRCh38
GRCh371282,746,082 - 82,752,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361281,270,220 - 81,276,330 (-)NCBINCBI36Build 36hg18NCBI36
Celera1282,413,647 - 82,420,144 (-)NCBICelera
Cytogenetic Map12q21.31NCBI
HuRef1279,803,324 - 79,809,821 (-)NCBIHuRef
CHM1_11282,711,940 - 82,718,437 (-)NCBICHM1_1
T2T-CHM13v2.01282,331,767 - 82,338,265 (-)NCBIT2T-CHM13v2.0
Ccdc59
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910105,677,340 - 105,683,371 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10105,676,928 - 105,683,694 (+)EnsemblGRCm39 Ensembl
GRCm3810105,841,479 - 105,847,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10105,841,067 - 105,847,833 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710105,278,535 - 105,284,566 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610105,245,589 - 105,251,620 (+)NCBIMGSCv36mm8
Celera10107,790,826 - 107,796,856 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1055.12NCBI
Ccdc59
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8743,029,272 - 43,035,655 (+)NCBIGRCr8
mRatBN7.2741,142,760 - 41,149,143 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl741,142,760 - 41,149,143 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx743,042,448 - 43,048,836 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0745,245,512 - 45,251,900 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0744,999,901 - 45,006,288 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0747,928,138 - 47,934,690 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl747,928,060 - 47,934,929 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0747,942,423 - 47,948,975 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4744,496,241 - 44,502,624 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1744,516,930 - 44,522,810 (+)NCBI
Celera738,018,929 - 38,025,316 (+)NCBICelera
Cytogenetic Map7q21NCBI
Ccdc59
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540520,731,464 - 20,738,657 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540520,732,649 - 20,738,678 (-)NCBIChiLan1.0ChiLan1.0
CCDC59
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21090,396,588 - 90,402,652 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11290,392,986 - 90,399,103 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01279,864,105 - 79,873,182 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11282,976,079 - 82,981,650 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1282,976,079 - 82,981,650 (-)Ensemblpanpan1.1panPan2
Ccdc59
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494535,897,608 - 35,905,140 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936507330,481 - 337,906 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936507330,481 - 337,810 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC59
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl599,358,330 - 99,364,091 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1599,358,726 - 99,364,092 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25104,173,569 - 104,178,937 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCDC59
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_023666037167,593,487 - 167,599,644 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc59
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248371,686,109 - 1,693,423 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248371,687,403 - 1,693,619 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCDC59
178 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 16 4 6 2 12 7 10 6
Low 1 5 6 6 2 6 4 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014119530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022428135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038496171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038496172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038496173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038688152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038688153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038688154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_849268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000036738   ⟹   ENSCAFP00000032147
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1524,364,779 - 24,373,419 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845019765   ⟹   ENSCAFP00845015471
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1524,743,676 - 24,752,295 (-)Ensembl
RefSeq Acc Id: XM_014119530   ⟹   XP_013975005
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11524,364,510 - 24,373,567 (-)NCBI
Dog10K_Boxer_Tasha1524,795,481 - 24,804,911 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022428135   ⟹   XP_022283843
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11524,364,510 - 24,373,567 (-)NCBI
Dog10K_Boxer_Tasha1524,795,481 - 24,804,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038496171   ⟹   XP_038352099
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11524,320,972 - 24,330,174 (-)NCBI
RefSeq Acc Id: XM_038496172   ⟹   XP_038352100
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11524,320,972 - 24,330,182 (-)NCBI
RefSeq Acc Id: XM_038496173   ⟹   XP_038352101
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11524,320,972 - 24,330,180 (-)NCBI
RefSeq Acc Id: XM_038558563   ⟹   XP_038414491
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01524,610,635 - 24,620,055 (-)NCBI
RefSeq Acc Id: XM_038558564   ⟹   XP_038414492
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01524,610,635 - 24,620,062 (-)NCBI
RefSeq Acc Id: XM_038558565   ⟹   XP_038414493
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01524,610,635 - 24,620,061 (-)NCBI
RefSeq Acc Id: XM_038622455   ⟹   XP_038478383
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01524,369,767 - 24,379,035 (-)NCBI
RefSeq Acc Id: XM_038622456   ⟹   XP_038478384
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01524,369,767 - 24,379,043 (-)NCBI
RefSeq Acc Id: XM_038622457   ⟹   XP_038478385
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01524,369,767 - 24,379,041 (-)NCBI
RefSeq Acc Id: XM_038688152   ⟹   XP_038544080
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01524,743,406 - 24,752,829 (-)NCBI
RefSeq Acc Id: XM_038688153   ⟹   XP_038544081
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01524,743,406 - 24,752,836 (-)NCBI
RefSeq Acc Id: XM_038688154   ⟹   XP_038544082
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01524,743,406 - 24,752,835 (-)NCBI
RefSeq Acc Id: XM_849268   ⟹   XP_854361
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11524,364,510 - 24,373,567 (-)NCBI
Dog10K_Boxer_Tasha1524,795,481 - 24,804,904 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013975005   ⟸   XM_014119530
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_854361   ⟸   XM_849268
- Peptide Label: isoform X1
- UniProtKB: A0A8C0P7U6 (UniProtKB/TrEMBL),   A0A8P0SQ22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022283843   ⟸   XM_022428135
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCAFP00000032147   ⟸   ENSCAFT00000036738
RefSeq Acc Id: XP_038352100   ⟸   XM_038496172
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038352101   ⟸   XM_038496173
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038352099   ⟸   XM_038496171
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038478384   ⟸   XM_038622456
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038478385   ⟸   XM_038622457
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038478383   ⟸   XM_038622455
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038544081   ⟸   XM_038688153
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038544082   ⟸   XM_038688154
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038544080   ⟸   XM_038688152
- Peptide Label: isoform X1
- UniProtKB: A0A8I3NCW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038414492   ⟸   XM_038558564
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038414493   ⟸   XM_038558565
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038414491   ⟸   XM_038558563
- Peptide Label: isoform X1
- UniProtKB: A0A8C0P7U6 (UniProtKB/TrEMBL),   A0A8P0SQ22 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845015471   ⟸   ENSCAFT00845019765

Promoters
RGD ID:13685938
Promoter ID:EPDNEW_C4008
Type:multiple initiation site
Name:CCDC59_1
Description:coiled-coil domain containing 59
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11524,373,433 - 24,373,493EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000023758 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030020496 UniProtKB/TrEMBL
  ENSCAFG00040012770 UniProtKB/TrEMBL
  ENSCAFG00845011151 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000036738.5 UniProtKB/TrEMBL
  ENSCAFT00030037605.1 UniProtKB/TrEMBL
  ENSCAFT00040023539.1 UniProtKB/TrEMBL
  ENSCAFT00845019765 ENTREZGENE
  ENSCAFT00845019765.1 UniProtKB/TrEMBL
InterPro Fyv7/TAP26 UniProtKB/TrEMBL
NCBI Gene CCDC59 ENTREZGENE
PANTHER PTHR15657 UniProtKB/TrEMBL
  THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 UniProtKB/TrEMBL
Pfam rRNA_processing UniProtKB/TrEMBL
PRINTS BR22PROTEIN UniProtKB/TrEMBL
UniProt A0A8C0P7U6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NCW6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SQ22 ENTREZGENE
UniProt Secondary A0A8P0SQ22 UniProtKB/TrEMBL
VGNC ID VGNC:38844 ENTREZGENE