LTK (leukocyte receptor tyrosine kinase) - Rat Genome Database

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Gene: LTK (leukocyte receptor tyrosine kinase) Canis lupus familiaris
Analyze
Symbol: LTK
Name: leukocyte receptor tyrosine kinase
RGD ID: 12319723
Description: ENCODES a protein that exhibits protein kinase activity (ortholog); receptor signaling protein tyrosine kinase activator activity (ortholog); transmembrane receptor protein tyrosine kinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cell surface receptor protein tyrosine kinase signaling pathway (ortholog); cellular response to retinoic acid (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); genetic disease (ortholog); FOUND IN membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leukocyte tyrosine kinase receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1308,541,328 - 8,550,108 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha308,600,243 - 8,608,930 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0308,675,659 - 8,684,364 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1308,596,963 - 8,605,660 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0308,704,371 - 8,709,292 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0308,836,123 - 8,844,819 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LTK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1308,541,328 - 8,550,108 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha308,600,243 - 8,608,930 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0308,675,659 - 8,684,364 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1308,596,963 - 8,605,660 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0308,704,371 - 8,709,292 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0308,836,123 - 8,844,819 (-)NCBIUU_Cfam_GSD_1.0
LTK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381541,503,637 - 41,513,827 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1541,503,637 - 41,513,887 (-)EnsemblGRCh38hg38GRCh38
GRCh371541,795,835 - 41,806,025 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361539,583,132 - 39,593,369 (-)NCBINCBI36Build 36hg18NCBI36
Build 341539,583,131 - 39,593,369NCBI
Celera1518,563,799 - 18,574,044 (-)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1518,644,053 - 18,654,294 (-)NCBIHuRef
CHM1_11541,914,406 - 41,924,652 (-)NCBICHM1_1
T2T-CHM13v2.01539,309,799 - 39,319,984 (-)NCBIT2T-CHM13v2.0
Ltk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392119,581,807 - 119,590,912 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2119,581,801 - 119,590,912 (-)EnsemblGRCm39 Ensembl
GRCm382119,751,326 - 119,760,431 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2119,751,320 - 119,760,431 (-)EnsemblGRCm38mm10GRCm38
MGSCv372119,577,062 - 119,586,167 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362119,442,767 - 119,451,872 (-)NCBIMGSCv36mm8
Celera2120,907,813 - 120,917,057 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.97NCBI
Ltk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83127,188,479 - 127,195,356 (-)NCBIGRCr8
mRatBN7.23106,734,675 - 106,741,552 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3106,734,676 - 106,743,369 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3110,409,972 - 110,416,829 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03119,005,519 - 119,012,376 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03116,665,912 - 116,672,769 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03111,553,679 - 111,560,556 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3111,553,680 - 111,560,556 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,102,134 - 118,109,011 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43106,266,245 - 106,273,122 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13106,162,954 - 106,174,551 (-)NCBI
Celera3105,645,555 - 105,652,432 (-)NCBICelera
Cytogenetic Map3q35NCBI
Ltk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554168,310,304 - 8,319,463 (-)NCBIChiLan1.0ChiLan1.0
LTK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21630,745,063 - 30,758,489 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11534,896,284 - 34,904,600 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01520,444,471 - 20,455,586 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11538,685,255 - 38,695,381 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1538,685,255 - 38,695,381 (-)Ensemblpanpan1.1panPan2
Ltk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864087,000,904 - 87,010,026 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364714,849,219 - 4,855,678 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364714,849,261 - 4,857,892 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LTK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11129,863,837 - 129,867,254 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21144,931,290 - 144,938,987 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LTK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12641,489,867 - 41,502,314 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2641,490,902 - 41,501,956 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604899,479,378 - 99,489,494 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ltk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248048,665,097 - 8,672,346 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248048,664,682 - 8,673,686 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LTK
126 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_038441805   ⟹   XP_038297733
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0308,675,659 - 8,684,364 (-)NCBI
RefSeq Acc Id: XM_038461489   ⟹   XP_038317417
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha308,600,243 - 8,608,930 (-)NCBI
RefSeq Acc Id: XM_038517569   ⟹   XP_038373497
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1308,596,963 - 8,605,660 (-)NCBI
RefSeq Acc Id: XM_038581102   ⟹   XP_038437030
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0308,836,123 - 8,844,819 (-)NCBI
RefSeq Acc Id: XM_038645470   ⟹   XP_038501398
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0308,704,371 - 8,709,292 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038373497   ⟸   XM_038517569
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038501398   ⟸   XM_038645470
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038297733   ⟸   XM_038441805
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038317417   ⟸   XM_038461489
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038437030   ⟸   XM_038581102
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
NCBI Gene LTK ENTREZGENE
VGNC ID VGNC:110598 ENTREZGENE