ELOVL6 (ELOVL fatty acid elongase 6) - Rat Genome Database

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Gene: ELOVL6 (ELOVL fatty acid elongase 6) Canis lupus familiaris
Analyze
Symbol: ELOVL6
Name: ELOVL fatty acid elongase 6
RGD ID: 12314927
Description: ENCODES a protein that exhibits acyltransferase activity, transferring groups other than amino-acyl groups (ortholog); INVOLVED IN fatty acid elongation (ortholog); long-chain fatty acid biosynthetic process (ortholog); positive regulation of cold-induced thermogenesis (ortholog); ASSOCIATED WITH congestive heart failure (ortholog); obesity (ortholog); FOUND IN fatty acid elongase complex (ortholog); integral component of endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: elongation of very long chain fatty acids protein 6; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13230,221,858 - 30,360,761 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3230,224,252 - 30,360,138 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3211,669,501 - 11,810,012 (+)NCBI
ROS_Cfam_1.03230,443,342 - 30,581,564 (-)NCBI
ROS_Cfam_1.0 Ensembl3230,394,846 - 30,581,340 (-)Ensembl
UMICH_Zoey_3.13230,436,830 - 30,574,542 (-)NCBI
UNSW_CanFamBas_1.03230,180,868 - 30,318,794 (-)NCBI
UU_Cfam_GSD_1.0329,529,507 - 9,670,539 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
ELOVL6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13230,221,858 - 30,360,761 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3230,224,252 - 30,360,138 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3211,669,501 - 11,810,012 (+)NCBI
ROS_Cfam_1.03230,443,342 - 30,581,564 (-)NCBI
ROS_Cfam_1.0 Ensembl3230,394,846 - 30,581,340 (-)Ensembl
UMICH_Zoey_3.13230,436,830 - 30,574,542 (-)NCBI
UNSW_CanFamBas_1.03230,180,868 - 30,318,794 (-)NCBI
UU_Cfam_GSD_1.0329,529,507 - 9,670,539 (+)NCBI
ELOVL6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384110,045,846 - 110,199,202 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4110,045,846 - 110,199,199 (-)EnsemblGRCh38hg38GRCh38
GRCh374110,967,002 - 111,119,771 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364111,189,992 - 111,339,220 (-)NCBINCBI36hg18NCBI36
Build 344111,328,146 - 111,477,375NCBI
Celera4108,263,951 - 108,413,724 (-)NCBI
Cytogenetic Map4q25NCBI
HuRef4106,702,334 - 106,852,302 (-)NCBIHuRef
CHM1_14110,946,738 - 111,096,521 (-)NCBICHM1_1
T2T-CHM13v2.04113,347,937 - 113,500,908 (-)NCBI
Elovl6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393129,326,035 - 129,432,144 (+)NCBIGRCm39mm39
GRCm39 Ensembl3129,326,004 - 129,432,144 (+)Ensembl
GRCm383129,532,386 - 129,638,495 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3129,532,355 - 129,638,495 (+)EnsemblGRCm38mm10GRCm38
MGSCv373129,235,304 - 129,341,413 (+)NCBIGRCm37mm9NCBIm37
MGSCv363129,524,461 - 129,630,513 (+)NCBImm8
Celera3136,042,332 - 136,148,508 (+)NCBICelera
Cytogenetic Map3G3NCBI
Elovl6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22218,063,682 - 218,174,767 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2218,063,804 - 218,171,186 (+)Ensembl
Rnor_6.02234,187,490 - 234,296,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2234,375,315 - 234,483,149 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2234,189,105 - 234,296,145 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02253,509,516 - 253,616,747 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42226,946,573 - 227,054,321 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12226,933,252 - 227,041,003 (+)NCBI
Celera2210,356,634 - 210,462,671 (+)NCBICelera
Cytogenetic Map2q42NCBI
Elovl6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955496179,977 - 301,918 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955496179,634 - 301,908 (+)NCBIChiLan1.0ChiLan1.0
ELOVL6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14113,112,941 - 113,260,883 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4113,110,466 - 113,260,444 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04102,545,815 - 102,695,536 (-)NCBIMhudiblu_PPA_v0panPan3
Elovl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530110,606,241 - 10,727,558 (+)NCBI
SpeTri2.0NW_0049365631,224,392 - 1,344,707 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELOVL6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8112,027,054 - 112,191,274 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18112,038,670 - 112,190,079 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28120,119,621 - 120,219,554 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ELOVL6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1757,949,910 - 58,095,637 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603736,623,125 - 36,769,288 (-)NCBIVero_WHO_p1.0
Elovl6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248384,468,192 - 4,593,556 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248384,469,321 - 4,593,919 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 11 6 6 6 2 5 4
Low 2 11 6 10 5 2
Below cutoff 5 6 8

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005639271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022413632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038444377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038444378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038444379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038518764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038518765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038518766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038518767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038581900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038581901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038581902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038646712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038646713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038646714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_545023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000018328   ⟹   ENSCAFP00000016975
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3230,224,252 - 30,360,138 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845053602   ⟹   ENSCAFP00845042120
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3230,394,846 - 30,579,386 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845053610   ⟹   ENSCAFP00845042126
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3230,442,546 - 30,579,386 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845053620   ⟹   ENSCAFP00845042132
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3230,443,964 - 30,581,340 (-)Ensembl
RefSeq Acc Id: XM_005639271   ⟹   XP_005639328
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13230,221,858 - 30,360,266 (-)NCBI
Dog10K_Boxer_Tasha3211,670,058 - 11,810,012 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022413632   ⟹   XP_022269340
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13230,221,858 - 30,360,761 (-)NCBI
Dog10K_Boxer_Tasha3211,669,501 - 11,810,012 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038444377   ⟹   XP_038300305
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03230,443,342 - 30,581,008 (-)NCBI
RefSeq Acc Id: XM_038444378   ⟹   XP_038300306
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03230,443,342 - 30,581,319 (-)NCBI
RefSeq Acc Id: XM_038444379   ⟹   XP_038300307
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03230,443,342 - 30,581,564 (-)NCBI
RefSeq Acc Id: XM_038518764   ⟹   XP_038374692
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13230,436,830 - 30,573,980 (-)NCBI
RefSeq Acc Id: XM_038518765   ⟹   XP_038374693
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13230,436,830 - 30,574,297 (-)NCBI
RefSeq Acc Id: XM_038518766   ⟹   XP_038374694
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13230,436,830 - 30,574,542 (-)NCBI
RefSeq Acc Id: XM_038518767   ⟹   XP_038374695
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13230,436,830 - 30,571,391 (-)NCBI
RefSeq Acc Id: XM_038581900   ⟹   XP_038437828
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0329,530,064 - 9,670,539 (+)NCBI
RefSeq Acc Id: XM_038581901   ⟹   XP_038437829
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0329,529,751 - 9,670,539 (+)NCBI
RefSeq Acc Id: XM_038581902   ⟹   XP_038437830
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0329,529,507 - 9,670,539 (+)NCBI
RefSeq Acc Id: XM_038646712   ⟹   XP_038502640
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03230,180,868 - 30,318,231 (-)NCBI
RefSeq Acc Id: XM_038646713   ⟹   XP_038502641
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03230,180,868 - 30,318,548 (-)NCBI
RefSeq Acc Id: XM_038646714   ⟹   XP_038502642
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03230,180,868 - 30,318,794 (-)NCBI
RefSeq Acc Id: XM_545023   ⟹   XP_545023
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13230,221,858 - 30,360,509 (-)NCBI
Dog10K_Boxer_Tasha3211,669,745 - 11,810,012 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_545023   ⟸   XM_545023
- Peptide Label: isoform X1
- UniProtKB: E2R1G6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005639328   ⟸   XM_005639271
- Peptide Label: isoform X1
- UniProtKB: E2R1G6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022269340   ⟸   XM_022413632
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000016975   ⟸   ENSCAFT00000018328
RefSeq Acc Id: XP_038374694   ⟸   XM_038518766
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038374693   ⟸   XM_038518765
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038374692   ⟸   XM_038518764
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038374695   ⟸   XM_038518767
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038502642   ⟸   XM_038646714
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038502641   ⟸   XM_038646713
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038502640   ⟸   XM_038646712
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038300307   ⟸   XM_038444379
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038300306   ⟸   XM_038444378
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038300305   ⟸   XM_038444377
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038437830   ⟸   XM_038581902
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038437829   ⟸   XM_038581901
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038437828   ⟸   XM_038581900
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCAFP00845042126   ⟸   ENSCAFT00845053610
RefSeq Acc Id: ENSCAFP00845042132   ⟸   ENSCAFT00845053620
RefSeq Acc Id: ENSCAFP00845042120   ⟸   ENSCAFT00845053602

Promoters
RGD ID:13688750
Promoter ID:EPDNEW_C6820
Type:multiple initiation site
Name:ELOVL6_1
Description:ELOVL fatty acid elongase 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13230,360,150 - 30,360,210EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011549 Ensembl
  ENSCAFG00030023087 UniProtKB/TrEMBL
  ENSCAFG00040024094 UniProtKB/TrEMBL
  ENSCAFG00845030224 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00030037044.1 UniProtKB/TrEMBL
  ENSCAFP00030037081.1 UniProtKB/TrEMBL
  ENSCAFP00040039235 UniProtKB/TrEMBL
  ENSCAFP00845042120.1 UniProtKB/TrEMBL
  ENSCAFP00845042126.1 UniProtKB/TrEMBL
  ENSCAFP00845042132 ENTREZGENE
  ENSCAFP00845042132.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030042460.1 UniProtKB/TrEMBL
  ENSCAFT00030042498.1 UniProtKB/TrEMBL
  ENSCAFT00040044905 UniProtKB/TrEMBL
  ENSCAFT00845053602.1 UniProtKB/TrEMBL
  ENSCAFT00845053610.1 UniProtKB/TrEMBL
  ENSCAFT00845053620 ENTREZGENE
  ENSCAFT00845053620.1 UniProtKB/TrEMBL
InterPro ELO_CS UniProtKB/TrEMBL
  ELO_fam UniProtKB/TrEMBL
  ELOVL6 UniProtKB/TrEMBL
NCBI Gene ELOVL6 ENTREZGENE
PANTHER PTHR11157 UniProtKB/TrEMBL
  PTHR11157:SF125 UniProtKB/TrEMBL
Pfam ELO UniProtKB/TrEMBL
PROSITE ELO UniProtKB/TrEMBL
UniProt A0A8C0P716_CANLF UniProtKB/TrEMBL
  A0A8C0RRR8_CANLF UniProtKB/TrEMBL
  A0A8I3QXF4_CANLF UniProtKB/TrEMBL
  A0A8I3QXG1_CANLF UniProtKB/TrEMBL
  A0A8I3SCL6_CANLF UniProtKB/TrEMBL
  E2R1G6 ENTREZGENE
VGNC ID VGNC:40324 ENTREZGENE