LOC609048 (dihydrofolate reductase) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: LOC609048 (dihydrofolate reductase) Canis lupus familiaris
Analyze
Symbol: LOC609048
Name: dihydrofolate reductase
RGD ID: 12314354
Description: ENCODES a protein that exhibits mRNA binding (ortholog); INVOLVED IN tetrahydrofolate metabolic process (ortholog); thymidine biosynthetic process (ortholog); ASSOCIATED WITH autosomal dominant thrombophilia due to protein S deficiency (ortholog); Joubert syndrome 8 (ortholog); protein S deficiency (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Bonobo
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11916,731,187 - 16,731,854 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1916,944,408 - 16,945,045 (+)NCBI
ROS_Cfam_1.01916,843,375 - 16,844,037 (+)NCBI
UMICH_Zoey_3.11916,800,539 - 16,801,196 (+)NCBI
UNSW_CanFamBas_1.01917,078,604 - 17,079,266 (+)NCBI
UU_Cfam_GSD_1.01917,550,180 - 17,550,815 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
LOC609048
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11916,731,187 - 16,731,854 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1916,944,408 - 16,945,045 (+)NCBI
ROS_Cfam_1.01916,843,375 - 16,844,037 (+)NCBI
UMICH_Zoey_3.11916,800,539 - 16,801,196 (+)NCBI
UNSW_CanFamBas_1.01917,078,604 - 17,079,266 (+)NCBI
UU_Cfam_GSD_1.01917,550,180 - 17,550,815 (+)NCBI
DHFR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl394,047,836 - 94,063,389 (-)EnsemblGRCh38hg38GRCh38
GRCh38394,057,922 - 94,063,389 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37393,776,766 - 93,781,760 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36395,259,456 - 95,264,350 (-)NCBINCBI36hg18NCBI36
Build 34395,259,459 - 95,264,350NCBI
Celera392,160,656 - 92,165,546 (-)NCBI
Cytogenetic Map3q11.2NCBI
HuRef391,139,383 - 91,144,684 (-)NCBIHuRef
CHM1_1393,739,771 - 93,745,071 (-)NCBICHM1_1
DHFR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1397,802,727 - 97,807,705 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0391,125,295 - 91,128,378 (-)NCBIMhudiblu_PPA_v0panPan3
DHFR2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12286,643,325 - 86,645,418 (+)NCBI
Vero_WHO_p1.0NW_02366604180,034,856 - 80,038,329 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_014121464   ⟹   XP_013976939
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11916,731,187 - 16,731,854 (+)NCBI
Dog10K_Boxer_Tasha1916,944,408 - 16,945,045 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038425601   ⟹   XP_038281529
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01916,843,375 - 16,844,037 (+)NCBI
RefSeq Acc Id: XM_038502484   ⟹   XP_038358412
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11916,800,539 - 16,801,196 (+)NCBI
RefSeq Acc Id: XM_038564512   ⟹   XP_038420440
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01917,550,180 - 17,550,815 (+)NCBI
RefSeq Acc Id: XM_038628640   ⟹   XP_038484568
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01917,078,604 - 17,079,266 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_013976939   ⟸   XM_014121464
- Sequence:
RefSeq Acc Id: XP_038358412   ⟸   XM_038502484
RefSeq Acc Id: XP_038484568   ⟸   XM_038628640
RefSeq Acc Id: XP_038281529   ⟸   XM_038425601
RefSeq Acc Id: XP_038420440   ⟸   XM_038564512
Protein Domains
DHFR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003969 UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000038964 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000006372 UniProtKB/TrEMBL
Gene3D-CATH 3.40.430.10 UniProtKB/TrEMBL
InterPro DHFR UniProtKB/TrEMBL
  DHFR-like_dom_sf UniProtKB/TrEMBL
  DHFR_CS UniProtKB/TrEMBL
  DHFR_dom UniProtKB/TrEMBL
NCBI Gene LOC609048 ENTREZGENE
PANTHER PTHR48069 UniProtKB/TrEMBL
Pfam DHFR_1 UniProtKB/TrEMBL
PROSITE DHFR_1 UniProtKB/TrEMBL
  DHFR_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53597 UniProtKB/TrEMBL
UniProt J9P092_CANLF UniProtKB/TrEMBL