IPO7 (importin 7) - Rat Genome Database

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Gene: IPO7 (importin 7) Canis lupus familiaris
Analyze
Symbol: IPO7
Name: importin 7
RGD ID: 12310746
Description: ENCODES a protein that exhibits histone binding (inferred); SMAD binding (inferred); small GTPase binding (inferred); INVOLVED IN innate immune response (ortholog); protein import into nucleus (ortholog); ASSOCIATED WITH genetic disease (ortholog); human immunodeficiency virus infectious disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nuclear envelope (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: importin-7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12132,692,206 - 32,748,140 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2132,691,933 - 32,746,124 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2132,259,943 - 32,315,887 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02133,570,892 - 33,626,829 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2133,570,873 - 33,626,610 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12132,834,650 - 32,890,535 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02133,001,050 - 33,056,915 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02133,294,796 - 33,350,686 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nuclear envelope  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IPO7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12132,692,206 - 32,748,140 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2132,691,933 - 32,746,124 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2132,259,943 - 32,315,887 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02133,570,892 - 33,626,829 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2133,570,873 - 33,626,610 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12132,834,650 - 32,890,535 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02133,001,050 - 33,056,915 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02133,294,796 - 33,350,686 (+)NCBIUU_Cfam_GSD_1.0
IPO7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38119,384,652 - 9,448,127 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl119,384,652 - 9,448,127 (+)EnsemblGRCh38hg38GRCh38
GRCh37119,406,199 - 9,469,674 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36119,362,780 - 9,423,651 (+)NCBINCBI36Build 36hg18NCBI36
Build 34119,362,779 - 9,423,651NCBI
Celera119,527,846 - 9,591,349 (+)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef119,077,758 - 9,141,170 (+)NCBIHuRef
CHM1_1119,405,091 - 9,468,610 (+)NCBICHM1_1
T2T-CHM13v2.0119,469,789 - 9,533,256 (+)NCBIT2T-CHM13v2.0
Ipo7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397109,617,522 - 109,655,816 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7109,617,481 - 109,655,816 (+)EnsemblGRCm39 Ensembl
GRCm387110,018,315 - 110,056,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7110,018,274 - 110,056,609 (+)EnsemblGRCm38mm10GRCm38
MGSCv377117,161,939 - 117,198,628 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367109,809,602 - 109,846,291 (+)NCBIMGSCv36mm8
Celera7109,992,202 - 110,028,891 (+)NCBICelera
Cytogenetic Map7E3NCBI
cM Map757.7NCBI
Ipo7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81173,497,472 - 173,537,707 (+)NCBIGRCr8
mRatBN7.21164,062,702 - 164,102,938 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,062,702 - 164,102,938 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1172,398,957 - 172,439,194 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,584,959 - 179,625,195 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01172,267,135 - 172,307,393 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01174,655,939 - 174,696,173 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1174,655,939 - 174,696,173 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01181,641,921 - 181,696,091 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,658,312 - 167,698,113 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11167,768,982 - 167,808,323 (+)NCBI
Celera1161,960,661 - 162,000,936 (+)NCBICelera
Cytogenetic Map1q33NCBI
Ipo7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541425,131,821 - 25,195,961 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541425,131,703 - 25,195,892 (+)NCBIChiLan1.0ChiLan1.0
IPO7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2911,827,388 - 11,889,994 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11111,785,980 - 11,848,626 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0119,521,055 - 9,583,638 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1119,256,060 - 9,318,610 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl119,256,060 - 9,318,333 (+)Ensemblpanpan1.1panPan2
Ipo7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494752,650,515 - 52,705,688 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365288,680,976 - 8,739,892 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365288,683,543 - 8,739,617 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IPO7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9111,662 - 163,104 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19111,657 - 163,137 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2912,448 - 49,237 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IPO7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,360,645 - 55,422,470 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl155,362,694 - 55,422,427 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038153,046,986 - 153,110,405 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ipo7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247661,519,937 - 1,594,018 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247661,519,946 - 1,594,014 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IPO7
506 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 10 6
Low 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000011732   ⟹   ENSCAFP00000010873
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2132,692,059 - 32,746,124 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000082104   ⟹   ENSCAFP00000053363
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2132,691,933 - 32,746,124 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845024325   ⟹   ENSCAFP00845019111
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2133,570,873 - 33,626,610 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845024339   ⟹   ENSCAFP00845019123
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2133,570,879 - 33,624,782 (+)Ensembl
RefSeq Acc Id: XM_038430477   ⟹   XP_038286405
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02133,570,892 - 33,626,829 (+)NCBI
RefSeq Acc Id: XM_038505782   ⟹   XP_038361710
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12132,834,650 - 32,890,535 (+)NCBI
RefSeq Acc Id: XM_038569015   ⟹   XP_038424943
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02133,294,796 - 33,350,686 (+)NCBI
RefSeq Acc Id: XM_038633194   ⟹   XP_038489122
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02133,001,050 - 33,056,915 (+)NCBI
RefSeq Acc Id: XM_542501   ⟹   XP_542501
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12132,692,206 - 32,748,140 (+)NCBI
Dog10K_Boxer_Tasha2132,259,943 - 32,315,887 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_542501   ⟸   XM_542501
- UniProtKB: A0A8C0S297 (UniProtKB/TrEMBL),   A0A8I3NQH3 (UniProtKB/TrEMBL),   A0A8I3NQG2 (UniProtKB/TrEMBL),   A0A8P0P307 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000010873   ⟸   ENSCAFT00000011732
RefSeq Acc Id: ENSCAFP00000053363   ⟸   ENSCAFT00000082104
RefSeq Acc Id: XP_038361710   ⟸   XM_038505782
RefSeq Acc Id: XP_038489122   ⟸   XM_038633194
RefSeq Acc Id: XP_038286405   ⟸   XM_038430477
- UniProtKB: A0A8C0S297 (UniProtKB/TrEMBL),   A0A8I3NQH3 (UniProtKB/TrEMBL),   A0A8I3NQG2 (UniProtKB/TrEMBL),   A0A8P0P307 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424943   ⟸   XM_038569015
- UniProtKB: A0A8C0S297 (UniProtKB/TrEMBL),   A0A8I3NQG2 (UniProtKB/TrEMBL),   A0A8I3NQH3 (UniProtKB/TrEMBL),   A0A8P0P307 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845019111   ⟸   ENSCAFT00845024325
RefSeq Acc Id: ENSCAFP00845019123   ⟸   ENSCAFT00845024339
Protein Domains
Importin N-terminal

Promoters
RGD ID:13687238
Promoter ID:EPDNEW_C5307
Type:multiple initiation site
Name:IPO7_1
Description:importin 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12132,692,230 - 32,692,290EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007259 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006964 UniProtKB/TrEMBL
  ENSCAFG00040009210 UniProtKB/TrEMBL
  ENSCAFG00845013643 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000011732.5 UniProtKB/TrEMBL
  ENSCAFT00000082104.2 UniProtKB/TrEMBL
  ENSCAFT00030012859.1 UniProtKB/TrEMBL
  ENSCAFT00030013003.1 UniProtKB/TrEMBL
  ENSCAFT00040017098.1 UniProtKB/TrEMBL
  ENSCAFT00845024325.1 UniProtKB/TrEMBL
  ENSCAFT00845024339 ENTREZGENE
  ENSCAFT00845024339.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Importin-beta_N UniProtKB/TrEMBL
  XPO2_central UniProtKB/TrEMBL
KEGG Report cfa:485383 UniProtKB/TrEMBL
NCBI Gene IPO7 ENTREZGENE
PANTHER IMPORTIN-7 UniProtKB/TrEMBL
  IMPORTIN-7, 8, 11 UniProtKB/TrEMBL
Pfam Cse1 UniProtKB/TrEMBL
  IBN_N UniProtKB/TrEMBL
PROSITE IMPORTIN_B_NT UniProtKB/TrEMBL
SMART IBN_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8C0MGI5_CANLF UniProtKB/TrEMBL
  A0A8C0S297 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NQG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NQH3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0P307 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:42067 ENTREZGENE