WASHC1 (WASH complex subunit 1) - Rat Genome Database

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Gene: WASHC1 (WASH complex subunit 1) Canis lupus familiaris
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Symbol: WASHC1
Name: WASH complex subunit 1
RGD ID: 12310247
Description: ENCODES a protein that exhibits gamma-tubulin binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN Arp2/3 complex-mediated actin nucleation (ortholog); dendritic cell antigen processing and presentation (ortholog); endocytic recycling (ortholog); PARTICIPATES IN retromer-mediated pathway; ASSOCIATED WITH chromosome 9p deletion syndrome (ortholog); schizophrenia (ortholog); FOUND IN autophagosome (ortholog); BLOC-1 complex (ortholog); centrosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC486746; LOW QUALITY PROTEIN: WASH complex subunit 1; WAS protein family homolog 1; WASH1
RGD Orthologs
Human
Mouse
Rat
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12742,102,694 - 42,118,850 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2742,099,886 - 42,116,339 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha274,564,689 - 4,581,124 (+)NCBI
ROS_Cfam_1.02742,461,263 - 42,477,702 (-)NCBI
UMICH_Zoey_3.12742,402,542 - 42,419,383 (-)NCBI
UNSW_CanFamBas_1.02742,372,199 - 42,388,638 (-)NCBI
UU_Cfam_GSD_1.0273,924,862 - 3,941,306 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
WASHC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12742,102,694 - 42,118,850 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2742,099,886 - 42,116,339 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha274,564,689 - 4,581,124 (+)NCBI
ROS_Cfam_1.02742,461,263 - 42,477,702 (-)NCBI
UMICH_Zoey_3.12742,402,542 - 42,419,383 (-)NCBI
UNSW_CanFamBas_1.02742,372,199 - 42,388,638 (-)NCBI
UU_Cfam_GSD_1.0273,924,862 - 3,941,306 (+)NCBI
WASHC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl914,475 - 73,865 (-)EnsemblGRCh38hg38GRCh38
GRCh38914,475 - 30,487 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37914,513 - 29,739 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36Y57,764,816 - 57,767,433 (-)NCBINCBI36hg18NCBI36
Cytogenetic Map9p24.3NCBI
CHM1_1914,312 - 29,934 (-)NCBICHM1_1
Washc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391766,418,524 - 66,427,498 (+)NCBIGRCm39mm39
GRCm39 Ensembl1766,418,540 - 66,427,498 (+)Ensembl
GRCm381766,111,529 - 66,120,503 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1766,111,545 - 66,120,503 (+)EnsemblGRCm38mm10GRCm38
MGSCv371766,460,886 - 66,469,843 (+)NCBIGRCm37mm9NCBIm37
MGSCv361766,011,089 - 66,020,046 (+)NCBImm8
Celera1770,419,820 - 70,428,779 (+)NCBICelera
Cytogenetic Map17E1.1NCBI
Washc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.29105,722,779 - 105,830,836 (+)NCBI
Rnor_6.0 Ensembl9113,918,858 - 113,936,860 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.09113,918,914 - 113,936,861 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.09113,443,351 - 113,459,272 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49104,885,755 - 104,896,516 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.19105,095,204 - 105,105,650 (+)NCBI
Celera9103,300,490 - 103,302,995 (-)NCBICelera
Cytogenetic Map9q37NCBI
Washc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945108,955,066 - 108,974,812 (+)NCBI
SpeTri2.0NW_004936606209,289 - 228,986 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WASHC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl567,391,277 - 67,412,434 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1567,395,737 - 67,412,408 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2569,630,618 - 69,644,438 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WASHC1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,075 - 27,633 (-)NCBI
ChlSab1.1 Ensembl118,116 - 22,842 (-)Ensembl
Washc1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624828249,994 - 269,347 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 20 4 6 4 6 6 12 8 10 6
Low 2 2 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000024933   ⟹   ENSCAFP00000023134
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2742,102,713 - 42,116,339 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000078699   ⟹   ENSCAFP00000045959
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2742,099,886 - 42,116,339 (-)Ensembl
RefSeq Acc Id: XM_005637321   ⟹   XP_005637378
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12742,102,694 - 42,118,850 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038439355   ⟹   XP_038295283
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02742,461,263 - 42,477,702 (-)NCBI
RefSeq Acc Id: XM_038459664   ⟹   XP_038315592
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha274,564,689 - 4,581,124 (+)NCBI
RefSeq Acc Id: XM_038514015   ⟹   XP_038369943
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12742,402,542 - 42,419,383 (-)NCBI
RefSeq Acc Id: XM_038576431   ⟹   XP_038432359
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0273,924,862 - 3,941,306 (+)NCBI
RefSeq Acc Id: XM_038641864   ⟹   XP_038497792
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02742,372,199 - 42,388,638 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_005637378   ⟸   XM_005637321
- Sequence:
RefSeq Acc Id: ENSCAFP00000045959   ⟸   ENSCAFT00000078699
RefSeq Acc Id: ENSCAFP00000023134   ⟸   ENSCAFT00000024933
RefSeq Acc Id: XP_038369943   ⟸   XM_038514015
RefSeq Acc Id: XP_038497792   ⟸   XM_038641864
RefSeq Acc Id: XP_038295283   ⟸   XM_038439355
RefSeq Acc Id: XP_038315592   ⟸   XM_038459664
RefSeq Acc Id: XP_038432359   ⟸   XM_038576431
Protein Domains
WH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015743 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000023134 UniProtKB/TrEMBL
  ENSCAFP00000045959 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000024933 UniProtKB/TrEMBL
  ENSCAFT00000078699 UniProtKB/TrEMBL
InterPro WASH1 UniProtKB/TrEMBL
  WASH1_WAHD UniProtKB/TrEMBL
  WH2_dom UniProtKB/TrEMBL
NCBI Gene LOC486746 ENTREZGENE
PANTHER PTHR23331 UniProtKB/TrEMBL
Pfam WASH_WAHD UniProtKB/TrEMBL
PROSITE WH2 UniProtKB/TrEMBL
UniProt A0A5F4BYV0_CANLF UniProtKB/TrEMBL
  E2QXP1_CANLF UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-12 WASHC1  WASH complex subunit 1  LOC486746  WAS protein family homolog 1  Symbol and/or name change 5135510 APPROVED