ANO9 (anoctamin 9) - Rat Genome Database

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Gene: ANO9 (anoctamin 9) Canis lupus familiaris
Analyze
Symbol: ANO9
Name: anoctamin 9
RGD ID: 12310162
Description: ENCODES a protein that exhibits chloride channel inhibitor activity (ortholog); intracellularly calcium-gated chloride channel activity (ortholog); INVOLVED IN calcium activated galactosylceramide scrambling (ortholog); calcium activated phosphatidylcholine scrambling (ortholog); calcium activated phosphatidylserine scrambling (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy (ortholog); early infantile epileptic encephalopathy (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: anoctamin-9; TMEM16J; transmembrane protein 16J
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11825,556,356 - 25,570,242 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1825,556,344 - 25,566,407 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1825,205,600 - 25,219,658 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01826,140,620 - 26,154,738 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1826,140,645 - 26,150,636 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11825,650,694 - 25,664,589 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01825,295,435 - 25,309,312 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01825,907,982 - 25,921,884 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ANO9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11825,556,356 - 25,570,242 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1825,556,344 - 25,566,407 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1825,205,600 - 25,219,658 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01826,140,620 - 26,154,738 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1826,140,645 - 26,150,636 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11825,650,694 - 25,664,589 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01825,295,435 - 25,309,312 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01825,907,982 - 25,921,884 (-)NCBIUU_Cfam_GSD_1.0
ANO9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811417,938 - 442,011 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11417,933 - 442,011 (-)EnsemblGRCh38hg38GRCh38
GRCh3711417,938 - 442,011 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611407,930 - 432,011 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411407,937 - 431,958NCBI
Celera11476,822 - 501,215 (-)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11233,000 - 256,840 (-)NCBIHuRef
CHM1_111416,390 - 440,621 (-)NCBICHM1_1
T2T-CHM13v2.011463,391 - 487,355 (-)NCBIT2T-CHM13v2.0
Ano9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,681,125 - 140,697,719 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7140,681,125 - 140,697,719 (-)EnsemblGRCm39 Ensembl
GRCm387141,101,212 - 141,117,806 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,101,212 - 141,117,806 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,287,118 - 148,303,705 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367140,952,545 - 140,959,994 (-)NCBIMGSCv36mm8
Celera7140,894,061 - 140,910,648 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.37NCBI
Ano9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81205,638,571 - 205,659,780 (-)NCBIGRCr8
mRatBN7.21196,208,863 - 196,230,381 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,197,341 - 196,229,900 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01213,908,389 - 213,929,291 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,908,982 - 213,921,208 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,827,278 - 220,848,630 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,298,523 - 201,323,708 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1193,843,679 - 193,864,215 (-)NCBICelera
Cytogenetic Map1q41NCBI
Ano9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,589,097 - 11,602,532 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,588,043 - 11,603,027 (+)NCBIChiLan1.0ChiLan1.0
ANO9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v292,786,560 - 2,811,652 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1111,941,904 - 1,994,999 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011415,570 - 441,389 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111452,613 - 478,047 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11453,054 - 477,950 (-)Ensemblpanpan1.1panPan2
Ano9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947289,285 - 309,395 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936888289,868 - 302,449 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936888289,309 - 306,184 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANO9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2232,194 - 250,935 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12232,761 - 250,966 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22162,294,641 - 162,309,154 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANO9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11235,246 - 253,391 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1235,702 - 249,990 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,297,653 - 97,312,012 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ano9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476621,998,613 - 22,006,791 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476621,994,071 - 22,007,336 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ANO9
177 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 6 6 11 8 5
Low 1 12 5 6 5 1 1 5 6
Below cutoff 4 4 1 1 5

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005631080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005631082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022405280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022405281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038454211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038454212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038500349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038627033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038627034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038627035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000010516   ⟹   ENSCAFP00000009748
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1825,556,344 - 25,566,407 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000068366   ⟹   ENSCAFP00000063519
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1825,556,344 - 25,566,407 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000077579   ⟹   ENSCAFP00000048890
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1825,556,344 - 25,566,249 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000091638   ⟹   ENSCAFP00000052914
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1825,556,344 - 25,566,407 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845052012   ⟹   ENSCAFP00845040805
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1826,140,645 - 26,150,636 (-)Ensembl
RefSeq Acc Id: XM_005631082   ⟹   XP_005631139
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11825,556,537 - 25,570,242 (-)NCBI
Dog10K_Boxer_Tasha1825,205,600 - 25,219,650 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038423991   ⟹   XP_038279919
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01826,140,620 - 26,154,738 (-)NCBI
RefSeq Acc Id: XM_038423992   ⟹   XP_038279920
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01826,140,620 - 26,154,737 (-)NCBI
RefSeq Acc Id: XM_038423993   ⟹   XP_038279921
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01826,140,620 - 26,154,729 (-)NCBI
RefSeq Acc Id: XM_038454211   ⟹   XP_038310139
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1825,205,600 - 25,219,658 (-)NCBI
RefSeq Acc Id: XM_038454212   ⟹   XP_038310140
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1825,205,600 - 25,219,658 (-)NCBI
RefSeq Acc Id: XM_038500349   ⟹   XP_038356277
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11825,650,694 - 25,664,589 (-)NCBI
RefSeq Acc Id: XM_038562912   ⟹   XP_038418840
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01825,907,982 - 25,921,884 (-)NCBI
RefSeq Acc Id: XM_038562913   ⟹   XP_038418841
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01825,907,982 - 25,921,884 (-)NCBI
RefSeq Acc Id: XM_038562914   ⟹   XP_038418842
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01825,907,982 - 25,921,876 (-)NCBI
RefSeq Acc Id: XM_038627033   ⟹   XP_038482961
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01825,295,435 - 25,309,312 (-)NCBI
RefSeq Acc Id: XM_038627034   ⟹   XP_038482962
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01825,295,435 - 25,309,312 (-)NCBI
RefSeq Acc Id: XM_038627035   ⟹   XP_038482963
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01825,295,435 - 25,309,304 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005631139   ⟸   XM_005631082
- Peptide Label: isoform X3
- UniProtKB: A0A8P0N8Z7 (UniProtKB/TrEMBL),   A0A8C0TLX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000048890   ⟸   ENSCAFT00000077579
RefSeq Acc Id: ENSCAFP00000009748   ⟸   ENSCAFT00000010516
RefSeq Acc Id: ENSCAFP00000063519   ⟸   ENSCAFT00000068366
RefSeq Acc Id: ENSCAFP00000052914   ⟸   ENSCAFT00000091638
RefSeq Acc Id: XP_038356277   ⟸   XM_038500349
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038482962   ⟸   XM_038627034
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038482961   ⟸   XM_038627033
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038482963   ⟸   XM_038627035
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038279919   ⟸   XM_038423991
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QWW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038279920   ⟸   XM_038423992
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TLX2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038279921   ⟸   XM_038423993
- Peptide Label: isoform X3
- UniProtKB: A0A8I3Q0M9 (UniProtKB/TrEMBL),   A0A8C0TLX2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038310140   ⟸   XM_038454212
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TLX2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038310139   ⟸   XM_038454211
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MEY0 (UniProtKB/TrEMBL),   A0A8C0QWW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418841   ⟸   XM_038562913
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TLX2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418840   ⟸   XM_038562912
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MEY0 (UniProtKB/TrEMBL),   A0A8C0QWW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418842   ⟸   XM_038562914
- Peptide Label: isoform X3
- UniProtKB: A0A8C0TLX2 (UniProtKB/TrEMBL),   A0A8P0N8Z7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845040805   ⟸   ENSCAFT00845052012
Protein Domains
Anoctamin transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006512 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006611 UniProtKB/TrEMBL
  ENSCAFG00040023058 UniProtKB/TrEMBL
  ENSCAFG00845029380 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000010516.5 UniProtKB/TrEMBL
  ENSCAFT00030012183.1 UniProtKB/TrEMBL
  ENSCAFT00030012266.1 UniProtKB/TrEMBL
  ENSCAFT00040042847.1 UniProtKB/TrEMBL
  ENSCAFT00845052012 ENTREZGENE
  ENSCAFT00845052012.1 UniProtKB/TrEMBL
InterPro Anoctamin UniProtKB/TrEMBL
  Anoctamin_TM UniProtKB/TrEMBL
NCBI Gene ANO9 ENTREZGENE
PANTHER PTHR12308 UniProtKB/TrEMBL
  PTHR12308:SF37 UniProtKB/TrEMBL
Pfam Anoctamin UniProtKB/TrEMBL
UniProt A0A8C0MEY0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MEZ0_CANLF UniProtKB/TrEMBL
  A0A8C0QWW6 ENTREZGENE
  A0A8C0TLX2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q0M9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0N8Z7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:37931 ENTREZGENE