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Gene: PRF1 (perforin 1) Canis lupus familiaris
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Symbol: PRF1
Name: perforin 1
Description: ENCODES a protein that exhibits calcium ion binding (inferred); identical protein binding (inferred); wide pore channel activity (inferred); INVOLVED IN cytolysis (inferred); defense response to tumor cell (inferred); defense response to virus (inferred); PARTICIPATES IN allograft rejection pathway; autoimmune thyroiditis pathway; graft-versus-host disease pathway; ASSOCIATED WITH aplastic anemia (ortholog); asthma (ortholog); autistic disorder (ortholog); FOUND IN cytolytic granule (inferred); cytoplasmic vesicle (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: perforin-1
Orthologs:
Homo sapiens (human) : PRF1 (perforin 1)  HGNC  Alliance
Mus musculus (house mouse) : Prf1 (perforin 1 (pore forming protein))  MGI  Alliance
Rattus norvegicus (Norway rat) : Prf1 (perforin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prf1 (perforin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PRF1 (perforin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prf1 (perforin 1)
Sus scrofa (pig) : PRF1 (perforin 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1421,497,865 - 21,502,429 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog Cytomap4 NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on PRF1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12307305
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.