ANKH (ANKH inorganic pyrophosphate transport regulator) - Rat Genome Database

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Gene: ANKH (ANKH inorganic pyrophosphate transport regulator) Canis lupus familiaris
Analyze
Symbol: ANKH
Name: ANKH inorganic pyrophosphate transport regulator
RGD ID: 12304194
Description: ENCODES a protein that exhibits ATP transmembrane transporter activity (ortholog); inorganic diphosphate transmembrane transporter activity (ortholog); INVOLVED IN ATP export (ortholog); bone mineralization (ortholog); calcium ion homeostasis (ortholog); ASSOCIATED WITH ankylosis (ortholog); arthritis (ortholog); autosomal dominant craniometaphyseal dysplasia (ortholog); FOUND IN extracellular region (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ankylosis, progressive homolog; progressive ankylosis protein homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1488,149,250 - 88,263,926 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl488,149,257 - 88,272,464 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha487,670,608 - 87,785,793 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0488,877,936 - 88,993,145 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl488,877,991 - 88,999,454 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1488,304,136 - 88,419,117 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0488,546,753 - 88,661,820 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0489,403,928 - 89,519,108 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ANKH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1488,149,250 - 88,263,926 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl488,149,257 - 88,272,464 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha487,670,608 - 87,785,793 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0488,877,936 - 88,993,145 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl488,877,991 - 88,999,454 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1488,304,136 - 88,419,117 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0488,546,753 - 88,661,820 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0489,403,928 - 89,519,108 (+)NCBIUU_Cfam_GSD_1.0
ANKH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38514,704,800 - 14,871,778 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl514,704,800 - 14,871,778 (-)EnsemblGRCh38hg38GRCh38
GRCh37514,704,909 - 14,871,887 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36514,762,019 - 14,924,876 (-)NCBINCBI36Build 36hg18NCBI36
Build 34514,762,018 - 14,924,876NCBI
Celera514,728,867 - 14,895,594 (-)NCBICelera
Cytogenetic Map5p15.2NCBI
HuRef514,677,712 - 14,844,731 (-)NCBIHuRef
CHM1_1514,704,654 - 14,871,772 (-)NCBICHM1_1
T2T-CHM13v2.0514,644,272 - 14,811,218 (-)NCBIT2T-CHM13v2.0
Ank
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391527,466,763 - 27,594,995 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1527,466,763 - 27,594,995 (+)EnsemblGRCm39 Ensembl
GRCm381527,466,677 - 27,594,909 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1527,466,677 - 27,594,909 (+)EnsemblGRCm38mm10GRCm38
MGSCv371527,396,432 - 27,524,664 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361527,411,402 - 27,539,630 (+)NCBIMGSCv36mm8
Celera1528,188,363 - 28,342,822 (+)NCBICelera
Cytogenetic Map15B1NCBI
cM Map1510.23NCBI
Ankh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8279,883,350 - 80,011,222 (+)NCBIGRCr8
mRatBN7.2278,153,027 - 78,280,181 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl278,153,026 - 78,280,187 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx285,240,253 - 85,367,690 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0283,361,989 - 83,489,422 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0278,394,033 - 78,521,764 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0280,131,563 - 80,256,948 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl280,131,563 - 80,256,954 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0299,796,579 - 99,921,964 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4279,289,427 - 79,418,518 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1279,234,387 - 79,363,480 (+)NCBI
Celera273,782,876 - 73,934,310 (+)NCBICelera
Cytogenetic Map2q22NCBI
Ankh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554263,992,671 - 4,130,754 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554263,992,671 - 4,130,754 (-)NCBIChiLan1.0ChiLan1.0
ANKH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2414,944,516 - 15,105,199 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1513,098,133 - 13,258,900 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0515,014,019 - 15,175,467 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1514,849,497 - 15,015,206 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl514,855,914 - 14,917,729 (-)Ensemblpanpan1.1panPan2
Ankh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213232,927,281 - 233,060,862 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366651,520,800 - 1,653,816 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366651,520,800 - 1,654,388 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl164,105,165 - 4,271,170 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1164,095,582 - 4,271,073 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,444,997 - 4,610,979 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANKH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1414,401,681 - 14,559,342 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl414,408,116 - 14,559,454 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606413,973,098 - 14,126,427 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ankh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475111,716,369 - 11,847,758 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475111,716,369 - 11,847,726 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ANKH
2305 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005619428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000022708   ⟹   ENSCAFP00000021091
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl488,149,257 - 88,266,279 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000075016   ⟹   ENSCAFP00000051248
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl488,156,775 - 88,263,467 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000075526   ⟹   ENSCAFP00000053931
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl488,149,257 - 88,265,729 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000083824   ⟹   ENSCAFP00000048207
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl488,149,257 - 88,263,944 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000084181   ⟹   ENSCAFP00000050377
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl488,155,585 - 88,263,944 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000088573   ⟹   ENSCAFP00000046007
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl488,149,257 - 88,265,729 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000091671   ⟹   ENSCAFP00000062637
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl488,202,376 - 88,263,467 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000092866   ⟹   ENSCAFP00000057332
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl488,149,257 - 88,272,464 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845006822   ⟹   ENSCAFP00845005433
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl488,877,991 - 88,999,454 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845006842   ⟹   ENSCAFP00845005451
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl488,877,991 - 88,993,890 (+)Ensembl
RefSeq Acc Id: XM_038474314   ⟹   XP_038330242
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1488,304,136 - 88,419,117 (+)NCBI
RefSeq Acc Id: XM_038474315   ⟹   XP_038330243
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1488,305,114 - 88,419,117 (+)NCBI
RefSeq Acc Id: XM_038501426   ⟹   XP_038357354
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha487,670,608 - 87,785,793 (+)NCBI
RefSeq Acc Id: XM_038501436   ⟹   XP_038357364
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha487,671,626 - 87,785,793 (+)NCBI
RefSeq Acc Id: XM_038535443   ⟹   XP_038391371
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0489,403,928 - 89,519,108 (+)NCBI
RefSeq Acc Id: XM_038535444   ⟹   XP_038391372
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0489,404,945 - 89,519,108 (+)NCBI
RefSeq Acc Id: XM_038599706   ⟹   XP_038455634
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0488,546,753 - 88,661,820 (+)NCBI
RefSeq Acc Id: XM_038599707   ⟹   XP_038455635
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0488,547,779 - 88,661,820 (+)NCBI
RefSeq Acc Id: XM_038664032   ⟹   XP_038519960
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0488,877,936 - 88,993,145 (+)NCBI
RefSeq Acc Id: XM_038664033   ⟹   XP_038519961
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0488,878,925 - 88,993,145 (+)NCBI
Ensembl Acc Id: ENSCAFP00000046007   ⟸   ENSCAFT00000088573
Ensembl Acc Id: ENSCAFP00000050377   ⟸   ENSCAFT00000084181
Ensembl Acc Id: ENSCAFP00000057332   ⟸   ENSCAFT00000092866
Ensembl Acc Id: ENSCAFP00000048207   ⟸   ENSCAFT00000083824
Ensembl Acc Id: ENSCAFP00000062637   ⟸   ENSCAFT00000091671
Ensembl Acc Id: ENSCAFP00000051248   ⟸   ENSCAFT00000075016
Ensembl Acc Id: ENSCAFP00000053931   ⟸   ENSCAFT00000075526
Ensembl Acc Id: ENSCAFP00000021091   ⟸   ENSCAFT00000022708
RefSeq Acc Id: XP_038330242   ⟸   XM_038474314
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038330243   ⟸   XM_038474315
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038455634   ⟸   XM_038599706
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038455635   ⟸   XM_038599707
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038519960   ⟸   XM_038664032
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L3E8 (UniProtKB/TrEMBL),   A0A8C0NGZ2 (UniProtKB/TrEMBL),   A0A8I3MR39 (UniProtKB/TrEMBL),   A0A8C0SV25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038519961   ⟸   XM_038664033
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SV25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038357354   ⟸   XM_038501426
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L3E8 (UniProtKB/TrEMBL),   A0A8C0NGZ2 (UniProtKB/TrEMBL),   A0A8I3MR39 (UniProtKB/TrEMBL),   A0A8C0SV25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038357364   ⟸   XM_038501436
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SV25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391371   ⟸   XM_038535443
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L3E8 (UniProtKB/TrEMBL),   A0A8C0NGZ2 (UniProtKB/TrEMBL),   A0A8C0SV25 (UniProtKB/TrEMBL),   A0A8I3MR39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391372   ⟸   XM_038535444
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SV25 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845005433   ⟸   ENSCAFT00845006822
Ensembl Acc Id: ENSCAFP00845005451   ⟸   ENSCAFT00845006842

Promoters
RGD ID:13683087
Promoter ID:EPDNEW_C1155
Type:initiation region
Name:ANKH_1
Description:ANKH inorganic pyrophosphate transport regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1488,149,308 - 88,149,368EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014290 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030015265 UniProtKB/TrEMBL
  ENSCAFG00040016465 UniProtKB/TrEMBL
  ENSCAFG00845003814 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000022708.5 UniProtKB/TrEMBL
  ENSCAFT00000075526.2 UniProtKB/TrEMBL
  ENSCAFT00030028158.1 UniProtKB/TrEMBL
  ENSCAFT00030028235.1 UniProtKB/TrEMBL
  ENSCAFT00040030382.1 UniProtKB/TrEMBL
  ENSCAFT00040030421.1 UniProtKB/TrEMBL
  ENSCAFT00040030452.1 UniProtKB/TrEMBL
  ENSCAFT00040030543.1 UniProtKB/TrEMBL
  ENSCAFT00040030638.1 UniProtKB/TrEMBL
  ENSCAFT00040030723.1 UniProtKB/TrEMBL
  ENSCAFT00845006822.1 UniProtKB/TrEMBL
  ENSCAFT00845006842 ENTREZGENE
  ENSCAFT00845006842.1 UniProtKB/TrEMBL
InterPro ANKH UniProtKB/TrEMBL
NCBI Gene ANKH ENTREZGENE
PANTHER PROGRESSIVE ANKYLOSIS PROTEIN HOMOLOG UniProtKB/TrEMBL
  PTHR28384 UniProtKB/TrEMBL
Pfam ANKH UniProtKB/TrEMBL
UniProt A0A8C0L3E8 ENTREZGENE
  A0A8C0NGD3_CANLF UniProtKB/TrEMBL
  A0A8C0NGZ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0STF6_CANLF UniProtKB/TrEMBL
  A0A8C0SU61_CANLF UniProtKB/TrEMBL
  A0A8C0SV25 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SVG9_CANLF UniProtKB/TrEMBL
  A0A8C0SWM4_CANLF UniProtKB/TrEMBL
  A0A8I3MJ96_CANLF UniProtKB/TrEMBL
  A0A8I3MR39 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0P3G9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:50869 ENTREZGENE