COMMD1 (copper metabolism domain containing 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: COMMD1 (copper metabolism domain containing 1) Canis lupus familiaris
Analyze
Symbol: COMMD1
Name: copper metabolism domain containing 1
RGD ID: 12302435
Description: ENCODES a protein that exhibits copper ion binding (ortholog); identical protein binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); copper ion homeostasis (ortholog); low-density lipoprotein particle clearance (ortholog); ASSOCIATED WITH allergic disease (ortholog); Chronic Hepatitis (ortholog); Copper-Overload Cirrhosis (ortholog); FOUND IN Cul2-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); endosome (ortholog); INTERACTS WITH copper atom; copper(0)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: COMM domain-containing protein 1; copper metabolism (Murr1) domain containing 1; MURR1; protein Murr1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11061,886,281 - 62,059,610 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1061,886,281 - 62,059,591 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1061,775,492 - 61,947,762 (+)NCBI
ROS_Cfam_1.01062,894,268 - 63,067,243 (+)NCBI
UMICH_Zoey_3.11062,578,128 - 62,750,820 (+)NCBI
UNSW_CanFamBas_1.01062,882,129 - 63,053,837 (+)NCBI
UU_Cfam_GSD_1.01063,177,646 - 63,350,655 (+)NCBI
Dog Cytomap10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
copper atom  (EXP)
copper(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:9949209   PMID:11809725   PMID:14568250   PMID:18305350   PMID:22879914   PMID:25053573   PMID:26965651   PMID:27049130   PMID:27727471   PMID:32053895  


Genomics

Comparative Map Data
COMMD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11061,886,281 - 62,059,610 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1061,886,281 - 62,059,591 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1061,775,492 - 61,947,762 (+)NCBI
ROS_Cfam_1.01062,894,268 - 63,067,243 (+)NCBI
UMICH_Zoey_3.11062,578,128 - 62,750,820 (+)NCBI
UNSW_CanFamBas_1.01062,882,129 - 63,053,837 (+)NCBI
UU_Cfam_GSD_1.01063,177,646 - 63,350,655 (+)NCBI
Dog Cytomap10q26NCBI
COMMD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl261,888,724 - 62,147,247 (+)EnsemblGRCh38hg38GRCh38
GRCh38261,888,391 - 62,136,066 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37262,115,526 - 62,368,321 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36261,986,307 - 62,216,709 (+)NCBINCBI36hg18NCBI36
Build 34262,044,453 - 62,274,855NCBI
Celera261,977,700 - 62,207,946 (+)NCBI
Cytogenetic Map2p15NCBI
HuRef261,871,871 - 62,101,672 (+)NCBIHuRef
CHM1_1262,045,803 - 62,293,462 (+)NCBICHM1_1
Commd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391122,849,728 - 22,934,539 (-)NCBIGRCm39mm39
GRCm39 Ensembl1122,846,136 - 22,932,382 (-)Ensembl
GRCm381122,899,728 - 22,984,539 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1122,896,136 - 22,982,382 (-)EnsemblGRCm38mm10GRCm38
MGSCv371122,799,728 - 22,882,284 (-)NCBIGRCm37mm9NCBIm37
MGSCv361122,799,728 - 22,882,284 (-)NCBImm8
Celera1125,035,441 - 25,117,915 (-)NCBICelera
Cytogenetic Map11A3.2NCBI
cM Map1114.22NCBI
Commd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21496,880,463 - 96,984,494 (-)NCBI
Rnor_6.0 Ensembl14107,664,255 - 107,760,191 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.014107,664,321 - 107,759,974 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.014107,804,733 - 107,835,993 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.014107,724,470 - 107,726,728 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414103,571,472 - 103,667,692 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1495,868,544 - 95,965,715 (-)NCBICelera
Cytogenetic Map14q22NCBI
Commd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542421,927,079 - 22,050,371 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542421,962,837 - 22,067,745 (-)NCBIChiLan1.0ChiLan1.0
COMMD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A63,121,490 - 63,349,256 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A63,121,521 - 63,349,131 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A61,970,830 - 62,216,677 (+)NCBIMhudiblu_PPA_v0panPan3
Commd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629221,150,249 - 21,324,134 (-)NCBI
SpeTri2.0NW_0049364917,247,160 - 7,421,039 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COMMD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl379,770,565 - 79,913,975 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1379,770,315 - 79,913,969 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2383,605,344 - 83,748,646 (-)NCBISscrofa10.2Sscrofa10.2susScr3
COMMD1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11444,839,460 - 45,068,764 (-)NCBI
ChlSab1.1 Ensembl1444,839,542 - 45,068,586 (-)Ensembl
Commd1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476211,302,730 - 11,407,074 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 21 5 6 5 6 6 12 8 10 6
Low 1 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000004956   ⟹   ENSCAFP00000004595
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1061,886,281 - 62,059,591 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000048096   ⟹   ENSCAFP00000037521
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1061,886,281 - 62,002,726 (+)Ensembl
RefSeq Acc Id: NM_001003055   ⟹   NP_001003055
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11061,886,281 - 62,059,610 (+)NCBI
Dog10K_Boxer_Tasha1061,775,492 - 61,947,762 (+)NCBI
ROS_Cfam_1.01062,894,300 - 63,067,243 (+)NCBI
UMICH_Zoey_3.11062,578,128 - 62,750,820 (+)NCBI
UNSW_CanFamBas_1.01062,882,129 - 63,053,837 (+)NCBI
UU_Cfam_GSD_1.01063,177,646 - 63,350,655 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038678747   ⟹   XP_038534675
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01062,894,268 - 63,002,414 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001003055   ⟸   NM_001003055
- UniProtKB: Q8WMD0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSCAFP00000004595   ⟸   ENSCAFT00000004956
RefSeq Acc Id: ENSCAFP00000037521   ⟸   ENSCAFT00000048096
RefSeq Acc Id: XP_038534675   ⟸   XM_038678747
- Peptide Label: isoform X1
Protein Domains
COMM

Promoters
RGD ID:13685081
Promoter ID:EPDNEW_C3149
Type:multiple initiation site
Name:COMMD1_1
Description:copper metabolism domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11061,886,296 - 61,886,356EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003090 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000004595 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000037521 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000004956 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFT00000048096 UniProtKB/TrEMBL
InterPro COMM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  COMMD1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Murr1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403590 UniProtKB/Swiss-Prot
NCBI Gene COMMD1 ENTREZGENE
PANTHER PTHR21199 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COMM_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  COMMD1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE COMM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt COMD1_CANLF UniProtKB/Swiss-Prot
  F1Q330_CANLF UniProtKB/TrEMBL
  J9NWH6_CANLF UniProtKB/TrEMBL
  Q8WMD0 ENTREZGENE
UniProt Secondary O97832 UniProtKB/Swiss-Prot
VGNC ID VGNC:39491 ENTREZGENE