OR52E8C (olfactory receptor family 52 subfamily E member 8C) - Rat Genome Database

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Gene: OR52E8C (olfactory receptor family 52 subfamily E member 8C) Canis lupus familiaris
Analyze
Symbol: OR52E8C (Ensembl: OR52E8)
Name: olfactory receptor family 52 subfamily E member 8C (Ensembl:olfactory receptor family 52 subfamily E member 8)
RGD ID: 12302391
Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC100685391; olfactory receptor 52E8-like
RGD Orthologs
Human
Mouse
Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12129,039,253 - 29,040,524 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2129,039,571 - 29,040,512 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2128,813,554 - 28,814,507 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02129,865,060 - 29,866,013 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2129,875,560 - 29,883,242 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12129,187,694 - 29,188,647 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02129,371,946 - 29,372,899 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02129,541,282 - 29,542,235 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
OR52E8C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12129,039,253 - 29,040,524 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2129,039,571 - 29,040,512 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2128,813,554 - 28,814,507 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02129,865,060 - 29,866,013 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2129,875,560 - 29,883,242 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12129,187,694 - 29,188,647 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02129,371,946 - 29,372,899 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02129,541,282 - 29,542,235 (-)NCBIUU_Cfam_GSD_1.0
OR52E8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38115,856,749 - 5,857,690 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl115,856,749 - 5,857,690 (-)EnsemblGRCh38hg38GRCh38
GRCh37115,877,979 - 5,878,920 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,834,555 - 5,835,508 (-)NCBINCBI36Build 36hg18NCBI36
Build 34115,834,554 - 5,835,508NCBI
Celera115,997,069 - 5,998,022 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef115,537,502 - 5,538,454 (-)NCBIHuRef
CHM1_1115,876,916 - 5,877,868 (-)NCBICHM1_1
T2T-CHM13v2.0115,912,809 - 5,915,649 (-)NCBIT2T-CHM13v2.0
Or52e8b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397104,673,232 - 104,674,173 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7104,670,577 - 104,677,667 (-)EnsemblGRCm39 Ensembl
GRCm387105,024,025 - 105,024,966 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,021,370 - 105,028,460 (-)EnsemblGRCm38mm10GRCm38
MGSCv377112,172,539 - 112,173,480 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367104,897,846 - 104,898,787 (-)NCBIMGSCv36mm8
Celera7105,299,145 - 105,300,086 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.73NCBI
Or52e8b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81168,824,792 - 168,825,745 (-)NCBIGRCr8
mRatBN7.21159,412,927 - 159,413,880 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1159,412,927 - 159,413,880 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1167,398,435 - 167,399,388 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01174,584,344 - 174,585,297 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01167,491,544 - 167,492,497 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01169,902,961 - 169,903,914 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1169,902,961 - 169,903,914 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01176,915,704 - 176,916,657 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41162,793,777 - 162,794,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11162,889,253 - 162,890,207 (-)NCBI
Celera1157,350,049 - 157,351,002 (-)NCBICelera
Cytogenetic Map1q32NCBI

Variants

.
Variants in OR52E8C
28 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

reproductive system
High
Medium
Low
Below cutoff 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000047232   ⟹   ENSCAFP00000038859
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2129,039,571 - 29,040,512 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845011109   ⟹   ENSCAFP00845008669
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2129,875,560 - 29,883,242 (-)Ensembl
RefSeq Acc Id: NM_001389001   ⟹   NP_001375930
RefSeq Status: INFERRED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2128,813,554 - 28,814,507 (-)NCBI
ROS_Cfam_1.02129,865,060 - 29,866,013 (-)NCBI
UMICH_Zoey_3.12129,187,694 - 29,188,647 (-)NCBI
UNSW_CanFamBas_1.02129,371,946 - 29,372,899 (-)NCBI
UU_Cfam_GSD_1.02129,541,282 - 29,542,235 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001375930 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000009496.4
  ENSCAFP00030016834.1
  ENSCAFP00040028715.1
  ENSCAFP00845008669.1
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000038859   ⟸   ENSCAFT00000047232
RefSeq Acc Id: NP_001375930   ⟸   NM_001389001
- UniProtKB: A0A8C0K6B7 (UniProtKB/TrEMBL),   A0A8C0K8S9 (UniProtKB/TrEMBL),   A0A8C0MTX2 (UniProtKB/TrEMBL),   A0A8I3MYB6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845008669   ⟸   ENSCAFT00845011109
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031086 Ensembl
  ENSCAFG00000047175 UniProtKB/TrEMBL
  ENSCAFG00030010437 UniProtKB/TrEMBL
  ENSCAFG00040017878 UniProtKB/TrEMBL
  ENSCAFG00845006274 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000010236.5 UniProtKB/TrEMBL
  ENSCAFT00030019300.1 UniProtKB/TrEMBL
  ENSCAFT00040033004.1 UniProtKB/TrEMBL
  ENSCAFT00845011109.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene LOC100685391 ENTREZGENE
PANTHER OLFACTORY RECEPTOR 52E8 UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 56B1-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0K6B7 ENTREZGENE
  A0A8C0K8S9 ENTREZGENE
  A0A8C0MTX2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SY74_CANLF UniProtKB/TrEMBL
  A0A8I3MYB6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:96635 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-04 OR52E8C  olfactory receptor family 52 subfamily E member 8C  LOC100685391  olfactory receptor 52E8-like  Symbol and/or name change 5135510 APPROVED