IGFBP5 (insulin like growth factor binding protein 5) - Rat Genome Database

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Gene: IGFBP5 (insulin like growth factor binding protein 5) Canis lupus familiaris
Analyze
Symbol: IGFBP5
Name: insulin like growth factor binding protein 5
RGD ID: 12301782
Description: ENCODES a protein that exhibits fibronectin binding (ortholog); insulin-like growth factor binding (ortholog); insulin-like growth factor I binding (ortholog); INVOLVED IN aging (ortholog); cellular response to cAMP (ortholog); cellular response to organic cyclic compound (ortholog); PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); congenital diaphragmatic hernia (ortholog); Coronary Disease (ortholog); FOUND IN insulin-like growth factor ternary complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: insulin-like growth factor-binding protein 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13723,575,265 - 23,596,970 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3723,579,841 - 23,596,870 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3724,403,819 - 24,425,502 (-)NCBI
ROS_Cfam_1.03723,603,056 - 23,624,922 (-)NCBI
UMICH_Zoey_3.13723,486,557 - 23,508,226 (-)NCBI
UNSW_CanFamBas_1.03723,439,644 - 23,461,314 (-)NCBI
UU_Cfam_GSD_1.03723,458,321 - 23,480,088 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30578659  


Genomics

Comparative Map Data
IGFBP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13723,575,265 - 23,596,970 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3723,579,841 - 23,596,870 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3724,403,819 - 24,425,502 (-)NCBI
ROS_Cfam_1.03723,603,056 - 23,624,922 (-)NCBI
UMICH_Zoey_3.13723,486,557 - 23,508,226 (-)NCBI
UNSW_CanFamBas_1.03723,439,644 - 23,461,314 (-)NCBI
UU_Cfam_GSD_1.03723,458,321 - 23,480,088 (-)NCBI
IGFBP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2216,672,105 - 216,695,549 (-)EnsemblGRCh38hg38GRCh38
GRCh382216,672,105 - 216,695,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372217,536,828 - 217,560,272 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,245,073 - 217,268,516 (-)NCBINCBI36hg18NCBI36
Build 342217,362,334 - 217,385,777NCBI
Celera2211,304,716 - 211,328,161 (-)NCBI
Cytogenetic Map2q35NCBI
HuRef2209,391,205 - 209,414,636 (-)NCBIHuRef
CHM1_12217,543,006 - 217,566,425 (-)NCBICHM1_1
Igfbp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39172,897,224 - 72,914,024 (-)NCBIGRCm39mm39
GRCm39 Ensembl172,897,091 - 72,914,043 (-)Ensembl
GRCm38172,858,065 - 72,874,865 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl172,857,932 - 72,874,884 (-)EnsemblGRCm38mm10GRCm38
MGSCv37172,904,639 - 72,921,439 (-)NCBIGRCm37mm9NCBIm37
MGSCv36172,791,272 - 72,808,072 (-)NCBImm8
Celera173,426,251 - 73,443,205 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map136.94NCBI
Igfbp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2974,452,371 - 74,464,953 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl980,150,211 - 80,167,033 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0980,154,230 - 80,166,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0979,924,622 - 79,937,205 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4972,003,637 - 72,016,263 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1972,150,618 - 72,163,245 (-)NCBI
Celera972,045,541 - 72,058,122 (-)NCBICelera
RH 3.4 Map9679.1RGD
Cytogenetic Map9q33NCBI
Igfbp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545316,530,110 - 16,550,733 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545316,530,110 - 16,550,733 (+)NCBIChiLan1.0ChiLan1.0
IGFBP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B222,534,967 - 222,558,432 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B222,534,967 - 222,558,432 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B103,932,983 - 103,956,475 (-)NCBIMhudiblu_PPA_v0panPan3
Igfbp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303171,959,265 - 171,978,245 (-)NCBI
SpeTri2.0NW_004936586647,553 - 666,595 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGFBP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15118,857,479 - 118,878,522 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115118,861,816 - 118,877,787 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215131,682,267 - 131,684,608 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IGFBP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110102,510,939 - 102,531,710 (-)NCBI
ChlSab1.1 Ensembl10102,510,897 - 102,531,724 (-)Ensembl
Vero_WHO_p1.0NW_02366604096,877,547 - 96,898,347 (+)NCBI
Igfbp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248238,434,614 - 8,454,879 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 8
Medium 4 16 2 6 1 6 10 4
Low 1 5 6 6 4 6 5 6 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000022995   ⟹   ENSCAFP00000021360
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3723,579,841 - 23,596,870 (-)Ensembl
RefSeq Acc Id: XM_038447903   ⟹   XP_038303831
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03723,603,056 - 23,624,922 (-)NCBI
RefSeq Acc Id: XM_038521911   ⟹   XP_038377839
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13723,486,557 - 23,508,226 (-)NCBI
RefSeq Acc Id: XM_038585694   ⟹   XP_038441622
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03723,458,321 - 23,480,088 (-)NCBI
RefSeq Acc Id: XM_038650075   ⟹   XP_038506003
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03723,439,644 - 23,461,314 (-)NCBI
RefSeq Acc Id: XM_847792   ⟹   XP_852885
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13723,575,265 - 23,596,970 (-)NCBI
Dog10K_Boxer_Tasha3724,403,819 - 24,425,502 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038303831 (Get FASTA)   NCBI Sequence Viewer  
  XP_038377839 (Get FASTA)   NCBI Sequence Viewer  
  XP_038441622 (Get FASTA)   NCBI Sequence Viewer  
  XP_038506003 (Get FASTA)   NCBI Sequence Viewer  
  XP_852885 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_852885   ⟸   XM_847792
- Sequence:
RefSeq Acc Id: ENSCAFP00000021360   ⟸   ENSCAFT00000022995
RefSeq Acc Id: XP_038377839   ⟸   XM_038521911
RefSeq Acc Id: XP_038506003   ⟸   XM_038650075
RefSeq Acc Id: XP_038303831   ⟸   XM_038447903
RefSeq Acc Id: XP_038441622   ⟸   XM_038585694
Promoters
RGD ID:13689144
Promoter ID:EPDNEW_C7212
Type:single initiation site
Name:IGFBP5_1
Description:insulin like growth factor binding protein 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13723,596,198 - 23,596,258EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014474 Ensembl, ENTREZGENE
Ensembl Protein ENSCAFP00000021360 ENTREZGENE
NCBI Gene IGFBP5 ENTREZGENE
VGNC ID VGNC:41906 ENTREZGENE