DEAF1 (DEAF1 transcription factor)

Gene: DEAF1 (DEAF1 transcription factor) Canis lupus familiaris

Analyze

Symbol:

DEAF1

Name:

DEAF1 transcription factor

RGD ID:

12301499

Description:

ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); INVOLVED IN behavioral fear response (ortholog); embryonic skeletal system development (ortholog); neural tube closure (ortholog); ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); autism spectrum disorder (ortholog); autosomal dominant intellectual developmental disorder (ortholog); FOUND IN cytoplasm (ortholog); RNA polymerase II transcription regulator complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DEAF1, transcription factor; deformed epidermal autoregulatory factor 1; deformed epidermal autoregulatory factor 1 homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DEAF1 (DEAF1 transcription factor)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Deaf1 (DEAF1, transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Deaf1 (DEAF1 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Deaf1 (DEAF1 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DEAF1 (DEAF1 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Deaf1 (DEAF1 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DEAF1 (DEAF1 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DEAF1 (DEAF1 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Deaf1 (DEAF1 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	25,711,683 - 25,733,144 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	25,711,706 - 25,733,069 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	25,382,588 - 25,403,978 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	26,318,212 - 26,339,654 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	26,318,216 - 26,339,646 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	25,827,765 - 25,849,168 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	25,472,793 - 25,494,209 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	26,085,115 - 26,106,510 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

attention deficit hyperactivity disorder (ISO)

autism spectrum disorder (ISO)

autosomal dominant intellectual developmental disorder (ISO)

Chanarin-Dorfman syndrome (ISO)

delta beta-thalassemia (ISO)

developmental and epileptic encephalopathy (ISO)

Developmental Disease (ISO)

Dyskinesias, Seizures, and Intellectual Developmental Disorder (ISO)

early infantile epileptic encephalopathy (ISO)

genetic disease (ISO)

immunodeficiency 39 (ISO)

intellectual disability (ISO)

Malocclusion, Angle Class III (ISO)

neuronal ceroid lipofuscinosis (ISO)

obesity (ISO)

prostate cancer (ISO)

Segawa Syndrome, Autosomal Recessive (ISO)

Vulto-van Silfout-de Vries syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

behavioral fear response (ISO)

embryonic skeletal system development (ISO)

negative regulation of DNA-templated transcription (IEA)

negative regulation of transcription by RNA polymerase II (IEA)

neural tube closure (ISO)

positive regulation of DNA-templated transcription (IEA)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of mammary gland epithelial cell proliferation (IEA)

regulation of transcription by RNA polymerase II (IEA,ISO)

visual learning (ISO)

Cellular Component

cytoplasm (ISO)

fibrillar center (IEA)

nucleoplasm (IEA)

nucleus (IEA)

RNA polymerase II transcription regulator complex (ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

DNA-binding transcription repressor activity, RNA polymerase II-specific (IEA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

DEAF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	25,711,683 - 25,733,144 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	25,711,706 - 25,733,069 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	25,382,588 - 25,403,978 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	26,318,212 - 26,339,654 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	26,318,216 - 26,339,646 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	25,827,765 - 25,849,168 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	25,472,793 - 25,494,209 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	26,085,115 - 26,106,510 (-)	NCBI		UU_Cfam_GSD_1.0

DEAF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	644,220 - 707,083 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	644,233 - 707,118 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	644,220 - 707,083 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	634,225 - 685,740 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	634,224 - 685,740	NCBI
Cytogenetic Map	11	p15.5	NCBI
HuRef	11	460,942 - 512,153 (-)	NCBI		HuRef
CHM1_1	11	643,451 - 694,662 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	694,847 - 758,083 (-)	NCBI		T2T-CHM13v2.0

Deaf1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	140,877,089 - 140,918,758 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	140,877,093 - 140,907,603 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	141,297,176 - 141,338,869 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	141,297,180 - 141,327,690 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	148,483,075 - 148,524,682 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	141,148,505 - 141,178,895 (-)	NCBI		MGSCv36	mm8
Celera	7	141,090,924 - 141,132,561 (-)	NCBI		Celera
Cytogenetic Map	7	F5	NCBI
cM Map	7	86.61	NCBI

Deaf1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	205,831,428 - 205,865,106 (-)	NCBI		GRCr8
mRatBN7.2	1	196,401,857 - 196,435,541 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	196,401,857 - 196,435,541 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	204,747,278 - 204,780,898 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	211,874,080 - 211,907,780 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	204,548,216 - 204,581,918 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	214,283,787 - 214,317,466 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	214,283,790 - 214,317,466 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	221,201,334 - 221,234,579 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	201,491,091 - 201,524,767 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	201,642,425 - 201,679,478 (-)	NCBI
Celera	1	194,035,728 - 194,069,227 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI

Deaf1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955476	11,398,448 - 11,423,654 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955476	11,398,187 - 11,422,633 (+)	NCBI	ChiLan1.0	ChiLan1.0

DEAF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	3,025,522 - 3,089,277 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	2,241,646 - 2,301,460 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	652,337 - 709,854 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	679,074 - 753,395 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

Deaf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	473,651 - 497,152 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936888	473,974 - 497,158 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936888	473,651 - 497,152 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DEAF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	404,533 - 427,542 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	404,514 - 427,584 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	246,503 - 269,570 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DEAF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	487,497 - 510,440 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	97,524,197 - 97,571,811 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Deaf1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624766	21,799,119 - 21,833,631 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624766	21,799,282 - 21,832,267 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in DEAF1
274 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	1		16		3		5		12	2	10	3
Low	4	5	6	6	3	6	1	6		6		3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022405288	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022405289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038424036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038424037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038424038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038454399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038454400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038500395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038500396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038500397	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038562957	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038562958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038562959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038627078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038627079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038627080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_540529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002615814	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002615815	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000212	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000010605 ⟹ ENSCAFP00000009831

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	25,711,706 - 25,733,069 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000066441 ⟹ ENSCAFP00000057158

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	25,721,074 - 25,730,766 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000079931 ⟹ ENSCAFP00000053544

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	25,715,424 - 25,733,069 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000080573 ⟹ ENSCAFP00000044074

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	25,721,074 - 25,733,069 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845030922 ⟹ ENSCAFP00845024233

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	18	26,318,216 - 26,339,646 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845031026 ⟹ ENSCAFP00845024310

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	18	26,322,130 - 26,339,646 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845031107 ⟹ ENSCAFP00845024363

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	18	26,327,606 - 26,339,646 (-)	Ensembl

RefSeq Acc Id:

XM_038424036 ⟹ XP_038279964

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	18	26,328,311 - 26,339,654 (-)	NCBI

RefSeq Acc Id:

XM_038424037 ⟹ XP_038279965

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	18	26,318,212 - 26,339,654 (-)	NCBI

RefSeq Acc Id:

XM_038424038 ⟹ XP_038279966

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	18	26,318,212 - 26,339,654 (-)	NCBI

RefSeq Acc Id:

XM_038454399 ⟹ XP_038310327

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	18	25,392,679 - 25,403,978 (-)	NCBI

RefSeq Acc Id:

XM_038454400 ⟹ XP_038310328

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	18	25,382,588 - 25,403,978 (-)	NCBI

RefSeq Acc Id:

XM_038500395 ⟹ XP_038356323

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	18	25,837,844 - 25,849,168 (-)	NCBI

RefSeq Acc Id:

XM_038500396 ⟹ XP_038356324

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	18	25,827,765 - 25,849,168 (-)	NCBI

RefSeq Acc Id:

XM_038500397 ⟹ XP_038356325

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	18	25,827,765 - 25,849,168 (-)	NCBI

RefSeq Acc Id:

XM_038562957 ⟹ XP_038418885

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	18	26,095,209 - 26,106,510 (-)	NCBI

RefSeq Acc Id:

XM_038562958 ⟹ XP_038418886

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	18	26,085,115 - 26,106,510 (-)	NCBI

RefSeq Acc Id:

XM_038562959 ⟹ XP_038418887

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	18	26,085,115 - 26,106,510 (-)	NCBI

RefSeq Acc Id:

XM_038627078 ⟹ XP_038483006

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	18	25,472,793 - 25,494,209 (-)	NCBI

RefSeq Acc Id:

XM_038627079 ⟹ XP_038483007

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	18	25,472,793 - 25,494,209 (-)	NCBI

RefSeq Acc Id:

XM_038627080 ⟹ XP_038483008

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	18	25,472,793 - 25,494,209 (-)	NCBI

RefSeq Acc Id:

XM_540529 ⟹ XP_540529

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	18	25,711,683 - 25,733,129 (-)	NCBI
Dog10K_Boxer_Tasha	18	25,382,588 - 25,403,978 (-)	NCBI

Sequence:

show sequence

TCGGTCCCGGCCTTCGGGCGGCCCCGGCTGGCGCCTTCGGGCGGGCTCGGCGGAGTCCGGATGG
AGGACTCGGACTCGGCCGCCAAGCAGCTGGGCCTGGCCGAGGCGGCGGCGGTGGCGGCCGCGGC
CGCTGTGGCGGCGGCGGCCGCGGCCGCGGCGGGAGGCGAGGCGGAGGAGCCGGTGCTCAGCAGG
GACGAGGACTCGGAGGAGGACGGAGACTCCGAGGCAGAGCGCGAGACGCGGCGGGTGACGGCCG
TGGCGGTGATGGCCGCCGAGCCCGGGCACATGGACATGGGCGCCGAGGCCCTGCCCGGCCCCGA
CGAGGCCGCCGCGGCCGCAGCCTTCGCAGAGGTGACCACTGTGACCGTGGCCAACGTGGGTGCC
TCCGCAGACAATGTCTTCACCACGTCCGTGGCGAACGCCGCCTCCCTCTCGGGACACGTTCTGT
CTGGCAGGACGGCACTGCAGATCGGGGACAGCCTAAACACCGAGAAGGCCACGCTGATTGTGGT
GCACACGGATGGGAGCATCGTGGAGACGTCAGGGCTGAAGGGGCCGGCCGCTCCTCTCACCCCA
GGCCCTCAGTGCCCTGCGAGTCCTGCAGCTCCCGGCCAGGACAGAGGCGGGACCAAGTATAACT
GGGACCCGTCGGTGTATGACAGCGAGCTGCCCGTGCGCTGCCGCAACATCAGCGGGACCCTGTT
CAAGAGCAGGCTGGGCTCAGGAGGCCGGGGCCGGTGCATCAAGCAGGGCGAGAACTGGTACAGC
CCCACGGAGTTCGAAGCCATGGCAGGACGAGCCAGCAGCAAAGACTGGAAAAGGAGCATCCGCT
ATGCGGGCAGGCCGCTGCAGTGCCTCATTCAGGACGGGATCCTAAACCCTCATGCTGCCTCTTG
CACCTGTGCCGCATGCTGTGACGACATGACCTTGAGTGGTCCGGTCAGGCTCTTTGTCCCCTAC
AAAAGGCGCAAGAAGGAGAACGAGCTGCCCACAACCCCCGTGAAGAAGGAGCCCCCCAAGAACA
TCACGCTGCTTCCCGCCACGGCTGCCACTGCCTTCACCGTGACCCCCTCAGGACAGATCACTAC
CTCGGGCGCGCTGACCTTTGACCGGGCATCCACAGTGGAGGCTACCGCCGTCATCTCTGAGAGC
CCAGCCCAGGGCGACGTCTTCGCGGGAGCCACGGTGCAAGAGGCAGGTGTGCAGCCCCCGTGCA
GGGTCGGCCATCCGGAGCCCCACTACCCCGGCTACCAGGACAGCTGTCAGATCGCGCCGTTTCC
AGAAGCTGCGTTGCCAACGTCTCATCCCAAAATAGTGCTGACCTCCCTGCCGGCCTTGGCGGTC
CCCCCCTCCACCCCCACCAAAGCCGTGTCCCCCGCCGTGGTGAATGGGCTGGAAATGTCCGAGC
AGCGGAGCTGGCTGTACCTGGAGGAGATGGTCAACTCCCTGCTGAGTACGGCGCAGCAGCTCAA
GACACTGTTTGAACAGGCCAAGCAGGCCAGCTCGTACCGGGAAGCCGCCGTGGCCCAGGCCCGA
GTCCAGGCGGATACAGAGCGCAAGGAGCAGTCCTGTGTCAACTGTGGCCGGGAGGCCCTGAGCG
AGTGCACCGGCTGCCACAAAGTCAACTACTGCTCGACCTTCTGCCAGCGCAAGGACTGGAAGGA
CCACCAGCACATGTGCGGCCAGTCGGCGGCCGTCACTGTCCAGGCGGACGAGGTCCATGTCACA
GACAGCGTGATGGAGAAGGTCACCGTGTGAGCTGCGGGTCCCTCCACAGTGCCGCGGGGCTGCC
GCAGGTCAGGGACCTCGGGGGACGTTAAGGAGAAGAAAACACTTGCTGGTCAAGTTGTTAACAG
ACTTTTAGTGACTGCGCCGTCGGCAATGAGCTCCCGCCGCCCGGAAGCCCGAGGGAGGCCGGGG
CAGCGGCTGGTGGACGCAGGCCCCAGCCCTCGGCGCCTTCTCACGGTGCTCTTTTTTATCGCCT
GGATCGTGAGCATCTGGTCTCACCCCGGTGTGTCGTGTGCTGTGACACACGTGTACATAACGTG
TCTGTCAATAAAGCTGCCGTGACTCCGGCACCAGCTTCCTGGGTGCCCAGCAGGTTGGGAGGGC
CTCGGGTCGGGTTCTCCTGACCCTGCGGTTTGGAGGTCGCAGCCCCCAGGCGTGGGGCCCGCCG
GAGCGTCCTCCCTGTGGCCAAGGCGGGAGCTCGGCATGGGCACCACCCCAGGCGCGTGGGCCGC
TCCTGTCCCATCCCTGAAGCATCGGCACCAGGTTGGACCCCAGGGCGCTCGGGGGCCGGCACAT
TTGGGCCCTGGGAACAGGACCTGCCTCCCTGCTGACCAGCACTGGCGCCCGAGGACCAGTCCCC
CACGTTCCGGAAGCTTCTGTTTCTGGAAATGCCCTTGTGGCTGTGGAACGCCTGACCCGCCGTC
TCCCTGTTTCCCTGGCTCTCCCAAGGCTCGGAGCGAAGAAGGCAAGACCCCCGTGAAGAGACGC
ACGTCCGTGGGTGGGCAAGCCGGCAGCCGCCAGGACCCTCTGCAACGTCGCTTGGTTCCACGCT
GGCCTCAAGTTTCTGTGAGCCGTATGCTCGGAGGTCGCCCCCAGCCTGGCACCCTCCCTGGACT
CCTACTTCCAGAAAGTTCCAAGTCTGCAGAACCCTGGAGCCTTGGCTCTGGGACACGGCCACGG
CAGGGGCTGAGGGGGCCCGGGGCGTGGTAGGAAGGGGGTGTGAGTGCCCATAGGGCCTGGGCCA
GCCCCCGCTCCCAGCTCTGTGGACCACGCAGCTTCTCGGGGTTTTCCTTTCCCAAGTGTAACAC
ATACCCGAGCCCTGTGCCCGCCGCCACCTCCCGGAGCTGAAGGCCGAGAAGTCTGCGTGGGGCC
CGGGCTGAGGACGGGCGATGGGGCACTCACCATCCCCCCGCGGGGCGCCCTCCTCAGCGCACGC
CTGGGGGTCCGTTCCCACAGGTGGAACAAGCCGGAGGGGGGCACCTCGCAGCTCTTGGCGGGTC
CCCGGGTCCCCGGTGCGCTGAGCGTCGGGACGGCAGGGAGAGGACCGCGGGGGACCCACACGTC
TGGAAATGCTCCAAACATGGACCGCCGGGCCGTCCCCACCCTGGGGGCACTGGCGCTCCTCCTG
GCGCTGGGGGCCCTGGCGGGGGGCGGGGGTCCAGATCTCAGCTCAGCCAGGGCATCATCTCAGG
GTCATGAGCGCAAGCCCTGCCTCGGCCTCCGCGCAGAGCATGGAGCTACTTGAAATAAAAGGAT
GGAGCCCTCAGGACTGCACGTTCTGGGGACAGTTTTCTAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038279964	(Get FASTA)	NCBI Sequence Viewer
	XP_038279965	(Get FASTA)	NCBI Sequence Viewer
	XP_038279966	(Get FASTA)	NCBI Sequence Viewer
	XP_038310327	(Get FASTA)	NCBI Sequence Viewer
	XP_038310328	(Get FASTA)	NCBI Sequence Viewer
	XP_038356323	(Get FASTA)	NCBI Sequence Viewer
	XP_038356324	(Get FASTA)	NCBI Sequence Viewer
	XP_038356325	(Get FASTA)	NCBI Sequence Viewer
	XP_038418885	(Get FASTA)	NCBI Sequence Viewer
	XP_038418886	(Get FASTA)	NCBI Sequence Viewer
	XP_038418887	(Get FASTA)	NCBI Sequence Viewer
	XP_038483006	(Get FASTA)	NCBI Sequence Viewer
	XP_038483007	(Get FASTA)	NCBI Sequence Viewer
	XP_038483008	(Get FASTA)	NCBI Sequence Viewer
	XP_540529	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000009831.6
	ENSCAFP00000044074.1
	ENSCAFP00000053544.2
	ENSCAFP00040019876.1
	ENSCAFP00040019907.1
	ENSCAFP00040019935.1
	ENSCAFP00040019993.1
	ENSCAFP00040020079.1
	ENSCAFP00040020139.1
	ENSCAFP00845024233
	ENSCAFP00845024233.1
	ENSCAFP00845024310.1
	ENSCAFP00845024363
	ENSCAFP00845024363.1

RefSeq Acc Id:	XP_540529 ⟸ XM_540529
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0SE58 (UniProtKB/TrEMBL), A0A8I3NTI3 (UniProtKB/TrEMBL), A0A8P0SBZ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEDSDSAAKQLGLAEAAAVAAAAAVAAAAAAAAGGEAEEPVLSRDEDSEEDGDSEAERETRRVT AVAVMAAEPGHMDMGAEALPGPDEAAAAAAFAEVTTVTVANVGASADNVFTTSVANAASLSGHV LSGRTALQIGDSLNTEKATLIVVHTDGSIVETSGLKGPAAPLTPGPQCPASPAAPGQDRGGTKY NWDPSVYDSELPVRCRNISGTLFKSRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSI RYAGRPLQCLIQDGILNPHAASCTCAACCDDMTLSGPVRLFVPYKRRKKENELPTTPVKKEPPK NITLLPATAATAFTVTPSGQITTSGALTFDRASTVEATAVISESPAQGDVFAGATVQEAGVQPP CRVGHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPSTPTKAVSPAVVNGLEMS EQRSWLYLEEMVNSLLSTAQQLKTLFEQAKQASSYREAAVAQARVQADTERKEQSCVNCGREAL SECTGCHKVNYCSTFCQRKDWKDHQHMCGQSAAVTVQADEVHVTDSVMEKVTV hide sequence

RefSeq Acc Id:

ENSCAFP00000009831 ⟸ ENSCAFT00000010605

RefSeq Acc Id:

ENSCAFP00000057158 ⟸ ENSCAFT00000066441

RefSeq Acc Id:

ENSCAFP00000044074 ⟸ ENSCAFT00000080573

RefSeq Acc Id:

ENSCAFP00000053544 ⟸ ENSCAFT00000079931

RefSeq Acc Id:	XP_038356325 ⟸ XM_038500397
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038356324 ⟸ XM_038500396
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038356323 ⟸ XM_038500395
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038483008 ⟸ XM_038627080
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038483007 ⟸ XM_038627079
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038483006 ⟸ XM_038627078
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038279966 ⟸ XM_038424038
- Peptide Label:	isoform X3
- UniProtKB:	A0A8P0SBZ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038279965 ⟸ XM_038424037
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0SE58 (UniProtKB/TrEMBL), A0A8I3NTI3 (UniProtKB/TrEMBL), A0A8P0SBZ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038279964 ⟸ XM_038424036
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SG65 (UniProtKB/TrEMBL), A0A8I3NY01 (UniProtKB/TrEMBL), A0A8C0SG08 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038310328 ⟸ XM_038454400
- Peptide Label:	isoform X3
- UniProtKB:	A0A8P0SBZ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038310327 ⟸ XM_038454399
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SG65 (UniProtKB/TrEMBL), A0A8I3NY01 (UniProtKB/TrEMBL), A0A8C0SG08 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038418887 ⟸ XM_038562959
- Peptide Label:	isoform X3
- UniProtKB:	A0A8P0SBZ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038418886 ⟸ XM_038562958
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0SE58 (UniProtKB/TrEMBL), A0A8I3NTI3 (UniProtKB/TrEMBL), A0A8P0SBZ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038418885 ⟸ XM_038562957
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SG08 (UniProtKB/TrEMBL), A0A8C0SG65 (UniProtKB/TrEMBL), A0A8I3NY01 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845024233 ⟸ ENSCAFT00845030922

RefSeq Acc Id:

ENSCAFP00845024363 ⟸ ENSCAFT00845031107

RefSeq Acc Id:

ENSCAFP00845024310 ⟸ ENSCAFT00845031026

Protein Domains

MYND-type SAND

Promoters

RGD ID:

13686469

Promoter ID:

EPDNEW_C4535

Type:

single initiation site

Name:

DEAF1_1

Description:

DEAF1, transcription factor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	18	25,733,067 - 25,733,127	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000006569	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00040012458	UniProtKB/TrEMBL
	ENSCAFG00845017450	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000010605.6	UniProtKB/TrEMBL
	ENSCAFT00000079931.2	UniProtKB/TrEMBL
	ENSCAFT00000080573.2	UniProtKB/TrEMBL
	ENSCAFT00040022937.1	UniProtKB/TrEMBL
	ENSCAFT00040022969.1	UniProtKB/TrEMBL
	ENSCAFT00040022999.1	UniProtKB/TrEMBL
	ENSCAFT00040023064.1	UniProtKB/TrEMBL
	ENSCAFT00040023154.1	UniProtKB/TrEMBL
	ENSCAFT00040023223.1	UniProtKB/TrEMBL
	ENSCAFT00845030922	ENTREZGENE
	ENSCAFT00845030922.1	UniProtKB/TrEMBL
	ENSCAFT00845031026.1	UniProtKB/TrEMBL
	ENSCAFT00845031107	ENTREZGENE
	ENSCAFT00845031107.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.390.10	UniProtKB/TrEMBL
	6.10.140.2220	UniProtKB/TrEMBL
InterPro	SAND-like_dom_sf	UniProtKB/TrEMBL
	SAND_dom	UniProtKB/TrEMBL
	Znf_MYND	UniProtKB/TrEMBL
NCBI Gene	DEAF1	ENTREZGENE
PANTHER	DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG	UniProtKB/TrEMBL
	PTHR10237	UniProtKB/TrEMBL
Pfam	SAND	UniProtKB/TrEMBL
	zf-MYND	UniProtKB/TrEMBL
PROSITE	SAND	UniProtKB/TrEMBL
	ZF_MYND_1	UniProtKB/TrEMBL
	ZF_MYND_2	UniProtKB/TrEMBL
SMART	SAND	UniProtKB/TrEMBL
Superfamily-SCOP	HIT/MYND zinc finger-like	UniProtKB/TrEMBL
	SSF63763	UniProtKB/TrEMBL
UniProt	A0A8C0SE38_CANLF	UniProtKB/TrEMBL
	A0A8C0SE58	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0SFL6_CANLF	UniProtKB/TrEMBL
	A0A8C0SG08	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0SG65	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0YWW5_CANLF	UniProtKB/TrEMBL
	A0A8I3NTI3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NY01	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3RZX7_CANLF	UniProtKB/TrEMBL
	A0A8P0SBZ7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0T5W9_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:39870	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-08-21	DEAF1	DEAF1 transcription factor		DEAF1, transcription factor	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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