BFSP2 (beaded filament structural protein 2) - Rat Genome Database

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Gene: BFSP2 (beaded filament structural protein 2) Canis lupus familiaris
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Symbol: BFSP2
Name: beaded filament structural protein 2
RGD ID: 12301079
Description: ENCODES a protein that exhibits structural constituent of eye lens (inferred); structural molecule activity (inferred); INVOLVED IN cell maturation (ortholog); cytoskeleton organization (ortholog); intermediate filament cytoskeleton organization (ortholog); ASSOCIATED WITH alkaptonuria (ortholog); cataract (ortholog); cataract 12 multiple types (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred); intermediate filament (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phakinin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12330,334,080 - 30,394,202 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2329,992,021 - 30,396,840 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2330,313,068 - 30,373,020 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02330,853,777 - 30,913,731 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2330,853,717 - 30,916,377 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12330,547,685 - 30,607,662 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02330,605,760 - 30,665,697 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02330,852,922 - 30,912,879 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BFSP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12330,334,080 - 30,394,202 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2329,992,021 - 30,396,840 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2330,313,068 - 30,373,020 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02330,853,777 - 30,913,731 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2330,853,717 - 30,916,377 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12330,547,685 - 30,607,662 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02330,605,760 - 30,665,697 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02330,852,922 - 30,912,879 (+)NCBIUU_Cfam_GSD_1.0
BFSP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383133,400,056 - 133,475,208 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3133,400,056 - 133,475,222 (+)EnsemblGRCh38hg38GRCh38
GRCh373133,118,900 - 133,194,052 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363134,601,480 - 134,676,746 (+)NCBINCBI36Build 36hg18NCBI36
Build 343134,601,487 - 134,676,754NCBI
Celera3131,545,338 - 131,620,496 (+)NCBICelera
Cytogenetic Map3q22.1NCBI
HuRef3130,499,190 - 130,574,278 (+)NCBIHuRef
CHM1_13133,082,138 - 133,157,359 (+)NCBICHM1_1
T2T-CHM13v2.03136,142,708 - 136,220,306 (+)NCBIT2T-CHM13v2.0
Bfsp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399103,302,123 - 103,357,608 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9103,302,123 - 103,357,619 (-)EnsemblGRCm39 Ensembl
GRCm389103,424,924 - 103,480,405 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9103,424,924 - 103,480,420 (-)EnsemblGRCm38mm10GRCm38
MGSCv379103,327,254 - 103,382,658 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369103,283,074 - 103,338,478 (-)NCBIMGSCv36mm8
Celera9102,975,927 - 103,032,126 (-)NCBICelera
Cytogenetic Map9F1NCBI
cM Map955.37NCBI
Bfsp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88112,885,087 - 112,942,246 (-)NCBIGRCr8
mRatBN7.28104,006,226 - 104,063,399 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8104,006,226 - 104,063,399 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8109,665,688 - 109,722,204 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08107,864,851 - 107,921,377 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08105,707,540 - 105,764,074 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08111,908,614 - 111,965,889 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8111,908,614 - 111,965,889 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08111,300,027 - 111,356,813 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48108,464,778 - 108,522,722 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera8103,381,967 - 103,438,712 (-)NCBICelera
Cytogenetic Map8q32NCBI
Bfsp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555015,083,456 - 5,145,256 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555015,083,456 - 5,145,256 (-)NCBIChiLan1.0ChiLan1.0
BFSP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22131,348,153 - 131,422,812 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13131,352,881 - 131,427,540 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03130,470,362 - 130,543,610 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13137,946,886 - 138,019,642 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3137,946,969 - 138,016,584 (+)Ensemblpanpan1.1panPan2
Bfsp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560269,871,832 - 69,939,471 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365296,632,197 - 6,699,998 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365296,632,292 - 6,699,968 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BFSP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1374,558,297 - 74,639,455 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11374,557,878 - 74,639,459 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21382,022,622 - 82,103,833 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BFSP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11556,854,537 - 56,920,987 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1556,855,060 - 56,918,760 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604129,840,900 - 29,906,937 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bfsp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247309,685,568 - 9,772,984 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247309,685,568 - 9,772,984 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in BFSP2
791 total Variants

Expression


Sequence


RefSeq Acc Id: ENSCAFT00000010363   ⟹   ENSCAFP00000009608
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2330,303,908 - 30,330,159 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000010379   ⟹   ENSCAFP00000009622
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2330,334,020 - 30,396,840 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000046081   ⟹   ENSCAFP00000037867
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2329,992,021 - 30,330,159 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000066538   ⟹   ENSCAFP00000044456
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2330,171,307 - 30,330,159 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000071346   ⟹   ENSCAFP00000045955
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2329,992,093 - 30,368,218 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845052707   ⟹   ENSCAFP00845041372
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2330,853,717 - 30,916,377 (+)Ensembl
RefSeq Acc Id: XM_038432361   ⟹   XP_038288289
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02330,853,777 - 30,913,731 (+)NCBI
RefSeq Acc Id: XM_038507659   ⟹   XP_038363587
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12330,547,685 - 30,607,662 (+)NCBI
RefSeq Acc Id: XM_038570900   ⟹   XP_038426828
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02330,852,922 - 30,912,879 (+)NCBI
RefSeq Acc Id: XM_038635093   ⟹   XP_038491021
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02330,605,760 - 30,665,697 (+)NCBI
RefSeq Acc Id: XM_846506   ⟹   XP_851599
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12330,334,080 - 30,394,202 (+)NCBI
Dog10K_Boxer_Tasha2330,313,068 - 30,373,020 (+)NCBI
Sequence:
RefSeq Acc Id: XP_851599   ⟸   XM_846506
- UniProtKB: A0A8P0SBT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000009622   ⟸   ENSCAFT00000010379
RefSeq Acc Id: ENSCAFP00000009608   ⟸   ENSCAFT00000010363
RefSeq Acc Id: ENSCAFP00000044456   ⟸   ENSCAFT00000066538
RefSeq Acc Id: ENSCAFP00000037867   ⟸   ENSCAFT00000046081
RefSeq Acc Id: ENSCAFP00000045955   ⟸   ENSCAFT00000071346
RefSeq Acc Id: XP_038363587   ⟸   XM_038507659
RefSeq Acc Id: XP_038491021   ⟸   XM_038635093
RefSeq Acc Id: XP_038288289   ⟸   XM_038432361
- UniProtKB: A0A8C0TFD5 (UniProtKB/TrEMBL),   A0A8C0LT24 (UniProtKB/TrEMBL),   A0A8I3Q457 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038426828   ⟸   XM_038570900
- UniProtKB: A0A8C0LT24 (UniProtKB/TrEMBL),   A0A8C0TFD5 (UniProtKB/TrEMBL),   A0A8I3Q457 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845041372   ⟸   ENSCAFT00845052707
Protein Domains
IF rod


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006414 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00000056661 UniProtKB/TrEMBL
  ENSCAFG00030007265 UniProtKB/TrEMBL
  ENSCAFG00040022001 UniProtKB/TrEMBL
  ENSCAFG00040022106 UniProtKB/TrEMBL
  ENSCAFG00845029760 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000010379.5 UniProtKB/TrEMBL
  ENSCAFT00000066538.2 UniProtKB/TrEMBL
  ENSCAFT00030013324.1 UniProtKB/TrEMBL
  ENSCAFT00040040884.1 UniProtKB/TrEMBL
  ENSCAFT00040041009.1 UniProtKB/TrEMBL
  ENSCAFT00845052707 ENTREZGENE
  ENSCAFT00845052707.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  Single helix bin UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
InterPro IF_rod_dom UniProtKB/TrEMBL
  Keratin_I UniProtKB/TrEMBL
  TMEM108 UniProtKB/TrEMBL
KEGG Report cfa:608938 UniProtKB/TrEMBL
NCBI Gene BFSP2 ENTREZGENE
PANTHER PTHR23239 UniProtKB/TrEMBL
  PTHR23239:SF32 UniProtKB/TrEMBL
  PTHR28673 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 108 UniProtKB/TrEMBL
Pfam Filament UniProtKB/TrEMBL
  TMEM108 UniProtKB/TrEMBL
PRINTS TYPE1KERATIN UniProtKB/TrEMBL
PROSITE IF_ROD_2 UniProtKB/TrEMBL
SMART Filament UniProtKB/TrEMBL
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/TrEMBL
UniProt A0A8C0LT24 ENTREZGENE
  A0A8C0TDR1_CANLF UniProtKB/TrEMBL
  A0A8C0TFD5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q457 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SBT2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:38441 ENTREZGENE